Cinnabarinic acid detection by IHC in human breast tumor Cinnabarinic acid detection by IHC in human breast tumor Cinnabarinic acid detection by IHC in human caudate putamen Specificity of anti- Cinnabarinic acid antibody Cinnabarinic acid

Cinnabarinic acid detection by IHC in human breast tumor

Immunohistochemical staining of human breast tumor tissue shows presence of Cinnabarinic acid in cells surrounding a necrotic area. Paraffin-embedded tumor tissue was subjected to pH=6 antigen retrieval before overnight incubation with primary anti-Cinnabarinic antibody (1/500 dilution). A polymer-conjugated secondary Ab was added and immunostaining was revealed using DAB.

Cinnabarinic acid antibody

Ref: IS005


The first and only validated anti-Cinnabarinic acid antibody available for research use. IHC validation of the 5C5-E10 mAb in human brain and breast tumor tissues revealed the presence, in specific cells, of Cinnabarinic acid, a tryptophan metabolite known for its immunomodulatory role.

 

Clonality Monoclonal antibody (clone 5C5-E10)
Host Mouse
Valided applications IHC
Specie reactivity Reacts with all species
References Not yet cited to our knowledge
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Format 50µL


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Product information Protocols References Technical support Reviews

Product overview

 

Product name Cinnabarinic acid antibody
Synonyms

2-amino- 3-oxo- 3H-phenoxazine-1,9-dicarboxylic acid antibody

Immunogen Conjugated Cinnabarinic acid
Isotype IgG1 k chain
Clone clone 5C5-E10
Specificity

When tested in competitive ELISA, the anti-Cinnabarinic acid antibody 5C5-E10 did not cross-react with its precursor, 3-OH-Anthranilic acid conjugates

Lot number

140201

 

 

Storage

 

Form

Liquid

Purity Purified IgG
Concentration

0,5 mg/ml

Storage

Store at +4°C for short term (1-2 months). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles.

Material safety datasheet Download MSDS
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Protocols

Immunohistochemistry (IHC)

Dilute at 1:200-1:2000. Perform heat antigen retrieval (pH=6) before initiating IHC staining protocol on paraffin-embedded and frozen sections

Immunofluorescence (IF)

Dilute at 1:100-1:1000 on paraffin-embedded and frozen sections. Perform heat antigen retrieval and incubate with fluorescent secondary antibody conjugate.

Comments

Optimal working dilutions must be determined by the end-user

Restrictions For research use only
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References

Antibody not yet cited. Submit an article and get a 10% discount.

 

Selected publications on Cinnabarinic acid:

 

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