Kynurenine/Kynurenic Acid/Quinolinic Acid  ELISA pack (3-KYNs ELISA pack) Kynurenine/Kynurenic Acid/Quinolinic Acid  ELISA pack (3-KYNs ELISA pack) KYN / KYNA / QA ELISA pack - Standard curves KYN, KYNA and QA along the Kynurenine Pathway

Kynurenine/Kynurenic Acid/Quinolinic Acid ELISA pack (3-KYNs ELISA pack)

The three kits included in the pack are ready to use. Highly sensitive, with a minimum sample volume of 25-50µL, they enable pre-clinical and clinical sample testings.

Kynurenine/Kynurenic Acid/Quinolinic Acid ELISA pack
(3-KYNs ELISA pack)

Ref: ISE-220102

 

The Kynurenine/Kynurenic Acid/Quinolinic acid ELISA pack enables quantitative measurements of tryptophan catabolism along the kynurenine pathway in large numbers of samples. The three kits included in the pack are ready to use. Highly sensitive, with a minimum sample volume of 25-50µL, they enable pre-clinical and clinical sample testings.

 

Sample type
Plasma, Serum
Kit capacity 3 x 96 tests
Sensitivity

LoD KYN: 47.5 ng/ml

LoD KYNA: 0.53 ng/ml

LoD QA: 6 ng/ml

Range

KYN: 100 - 10000 ng/ml

KYNA: 1.40 - 74 ng/ml
QA: 25 - 2000 ng/ml

Species reactivity Reacts with all species
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Product information Key steps References Technical support Reviews

Product overview

Product name

Kynurenine/Kynurenic Acid/Quinolinic Acid ELISA pack

Description Three enzyme immunoassays (ELISA) allowing the quantitative determination of L-Kynurenine, Kynurenic acid and Quinolinic acid in serum samples.
Labels CE
Format 3 x 96-well plate
Samples Serum
Minimum sample volume 20-50 µL
Cross specie-reactivity React with all species
Standard range

KYN: 100 - 10000 ng/ml
KYNA: 1.40 - 74 ng/ml

QA: 200 - 2000 µg/ml

Sensitivity

LoD KYN: 47.5 ng/ml
LoD KYNA: 0.53 ng/ml

LoD QA: 6 ng/ml

Specificity

No significant cross-reactivity was observed analogs for each kit. See product pages for L-Kynurenine ELISAKynurenic acid ELISA and Quinolinic acid ELISA.

Storage Store at 2-8°C for to 6 months.
Datasheets Instructions for use - KYN kitInstructions for use - KYNA kitInstructions for use - QA kit
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Key steps

Sample collection & storage

Serum: Do not use lipemic, haemolytic samples, as well as samples containing precipitates or fibrin strands. Store samples at 2-8°C for up to 48h or -20°C for longer period (up to 6 months).

Sample preparation

KYN: Sample acylation (90 min)

KYNA: Sample derivatization (90 min) 
QA: Sample acylation (120 min)

ELISA Antisera overnight incubation, revelation and read steps (1h).
Detailed protocol Instructions for use - KYN kitInstructions for use - KYNA kitInstructions for use - QA kit
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References

KYN ELISA citations :

 

Selected articles on Kynurenic acid:


Selected articles on Quinolinic acid:

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