# Immusmol --- ## Pages - [Worry-free warranty](https://www.immusmol.com/worry-free-warranty/): Last updated: 28/07/2025 IMMUSMOL offers warranties on purchased products (worry-free warranty): 30-Day Free Return & Refund Customer may return any... - [Metanephrines ELISA kits](https://www.immusmol.com/shop/metanephrines-elisa-kits/): Our Metanephrines ELISA kits enable fast & easy measurement of Metanephrine (metadrenaline) and Normetanephrine (Normetadrenaline) in plasma and urine samples. Other catecholamines, such as Epinephrine, Norepinephrine, and Dopamine, can be quantified with the same product range. - [Kynurenine pathway ELISA kits:  Easy & Fast quantification of Tryptophan metabolites](https://www.immusmol.com/shop/kynurenine-pathway-elisa-kits-easy-fast-quantification-tryptophan-metabolites/): We have developed a unique range of ELISA kits to assess Tryptophan metabolism along the Kynurenine pathway. Highly sensitive, featuring low minimal sample volumes, and easy-to-use, our Kynurenines ELISA kits constitute an alternative to LC/MS for the quantification of L-Tryptophan, L-Kynurenine, Kynurenic acid, and Quinolinic acid in biological fluids: cell culture supernatants, serum, plasma, and urine. - [Arginine metabolism ELISA kits](https://www.immusmol.com/shop/arginine-metabolism-elisa-kits-sensitive-fast-easy-to-use-research-assays/): Our range of ELISA kits for arginine and its metabolites enables rapid and easy measurements in cell culture supernatant, serum, and plasma samples. The quantitative assays require low minimal sample volumes (20 to 50 μL). An ELISA pack is available to measure the Arginine/Ornithine ratio, as well as ELISA kits to quantify polyamines. - [ELISA kits for the measurement of hormones](https://www.immusmol.com/shop/elisa-kits-for-the-measurement-of-hormones/): Our ELISA kits enable the quantification of Thyroid hormones, Androgens, Progestogens, Estrogens, Corticoids, and Neuroendocrine tumor markers in plasma, urine and saliva. - [ELISA kits for the measurement of catecholamines](https://www.immusmol.com/shop/catecholamines-elisa-kits-fast-easy-quantification-of-adrenaline-noradrenaline-and-dopamine/): Our catecholamine ELISA kits permit easy and accurate measurements of Epinephrine (Adrenaline), Norepinephrine (Noradrenaline), and Dopamine levels in preclinical samples such as 2D cell culture and 3D organoid supernatants, microdialysates, as well as fast testing of clinical samples such as plasma, serum, and urine. - [ELISA kits for the Measurement of Thyroid Function Markers in Serum and Plasma](https://www.immusmol.com/shop/elisa-kits-for-the-measurement-of-thyroid-function-markers-in-serum-and-plasma/): Immusmol provides a comprehensive range of robust and reliable ELISA kits for the precise quantification of thyroid hormones. Our assays facilitate accurate diagnosis of thyroid disorders, including hypothyroidism, hyperthyroidism, thyroiditis, Graves’ disease, and Hashimoto’s thyroiditis. Additionally, our kits support investigations into thyroid hormone metabolism abnormalities such as non-thyroidal illness syndrome (euthyroid sick syndrome) and elevated reverse T3 levels. They are also ideally suited for assessing thyroid function across diverse research fields, including cardiovascular, neurological, reproductive, and developmental biology. - [ELISA kits for the Measurement of Androgens and Steroid Hormone Markers](https://www.immusmol.com/shop/elisa-kits-for-the-measurement-of-androgen-and-steroid-hormone-markers-in-serum-plasma-and-saliva/): Immusmol offers a comprehensive portfolio of ELISA kits for accurate measurement of essential androgens and steroid hormones. Our assays facilitate the diagnosis of endocrine disorders, such as polycystic ovary syndrome (PCOS), adrenal hyperplasia, adrenal tumors, and androgen-secreting tumors. They are also valuable tools for assessing male reproductive health—including hypogonadism and infertility—as well as evaluating androgen excess in females. Additionally, our immunoassays support the monitoring of hormone replacement therapies, including androgen supplementation and anti-androgen treatments in prostate cancer, and enable the detection of steroid use in sports medicine and anti-doping research. - [ELISA kits for the Measurement of Progestogens](https://www.immusmol.com/shop/elisa-kits-for-the-measurement-of-progestogens/): Explore ELISA kits for fast and accurate measurement of progestogens like Progesterone,17-OH-Progesterone, and Pregnenolone in saliva, serum & plasma. - [Corticoid ELISA kits for the Measurement of Adrenal Hormones & Stress Biomarkers](https://www.immusmol.com/shop/corticoid-elisa-kits-for-the-measurement-of-adrenal-hormones-stress-biomarkers-in-serum-plasma-urine-and-saliva/): Immusmol provides an extensive portfolio of ELISA kits designed for precise quantification of adrenal hormones and stress biomarkers. Our assays support accurate diagnosis of adrenal disorders, including Addison’s disease, Cushing’s syndrome, adrenal insufficiency, adrenal adenoma and carcinoma, as well as Conn’s syndrome (primary hyperaldosteronism). Additionally, these immunoassays facilitate research in stress biology and circadian rhythm, encompassing psychobiology, psychosocial stress, cortisol regulation, and chronic stress studies. They also offer valuable insights for endocrinology and metabolic disorder research. - [ELISA kits for the Measurement of Estrogens](https://www.immusmol.com/shop/elisa-kits-for-the-measurement-of-estrogens-female-sex-steroids-in-serum-plasma-and-saliva/): Immusmol provides rigorously validated ELISA kits for precise quantification of female sex steroid hormones, including estrogens. Our immunoassays facilitate the accurate diagnosis of female reproductive disorders such as polycystic ovary syndrome (PCOS), ovarian insufficiency, menopause-related conditions, amenorrhea, and infertility. These kits are also valuable for monitoring high-risk pregnancies and detecting hormone-dependent malignancies, including breast, ovarian, and endometrial cancers. Furthermore, our assays effectively support the monitoring of hormone replacement therapies and fertility treatments. - [ELISA kits for the Measurement of Neuroendocrine Tumor Markers](https://www.immusmol.com/shop/elisa-kits-for-the-measurement-of-neuroendocrine-tumor-markers/): Fast & robust ELISA kits for the measurement of neuroendocrine tumors: Chromogranin A, 5-HIAA, Metanephrines, ... in urine and plasma samples - [Validated antibodies for neurotransmitter imaging (IF or IHC staining)](https://www.immusmol.com/shop/validated-antibodies-for-neurotransmitter-imaging-if-or-ihc-staining/): We developed and validated a full range of antibodies for neurotransmitter imaging. Combined with the STAINperfect immuno-staining kit, our antibodies enable the visualization of neuromediators by immunofluorescence (IF) or ImmunoHistoChemistry (IHC) in cell cultures, tissue sections, and whole mounts. A range of research ELISA kits for easy quantification of neurotransmitters is also available. - [Validated antibodies for amino acid imaging](https://www.immusmol.com/shop/validated-antibodies-amino-acid-imaging/): We developed and validated a range of antibodies for the visualization of amino acids and their metabolites in biological samples, with a focus on arginine and tryptophan metabolism. Combined with the STAINperfect immuno-staining kit, our primary antibodies allow for high-quality IF and IHC imaging. A range of research ELISA kits for the quantification of amino acids is also available. - [Primary antibodies to assess arginine metabolism](https://www.immusmol.com/shop/antibodies-to-assess-arginine-metabolism/): ImmuSmol developed a unique range of antibodies to visualize amino acid L-Arginine and its key metabolites, such as L-Ornithine and L-Citrulline, as well as polyamines like N1-Acetyl-Spermidine and N8-Acetyl-Spermidine, and related amino acids such as L-Lysine and Homoarginine. A range of research ELISA kits for easy measurements of Arginine metabolism is also available. - [Validated Antibodies to Tryptophan Metabolites (Kynurenines)](https://www.immusmol.com/shop/validated-antibodies-to-tryptophan-metabolites-kynurenines/): ImmuSmol developed and validated a unique range of antibodies to visualize L-Tryptophan metabolites along the kynurenine pathway. Available as mouse monoclonals or rabbit polyclonals, our antibodies to kynurenines were tested for IF and IHC, mainly in mouse and human tissues. A range of research ELISA kits for easy measurements of tryptophan metabolism is also available. - [Antibodies for catecholamine imaging (including dopamine & its metabolites)](https://www.immusmol.com/shop/antibodies-to-dopamine-its-metabolites-catecholamines/): We developed and validated a range of antibodies to evidence dopamine, its precursors, and downstream metabolites in cell cultures and tissue samples (IF or IHC). Combined with the STAINperfect immuno-staining kit, our primary antibodies accurately reach their targets. A range of research ELISA kits for catecholamine quantification is also available. - [ELISA kits for the quantification of amino acids​](https://www.immusmol.com/shop/elisa-kits-quantification-amino-acids/): Our range of highly sensitive research ELISA kits enables fast & easy quantification of amino acids in cell supernatant, plasma, serum, and urine samples. Additional ELISA kits for the analysis of downstream metabolic pathways are also available, including glutamine metabolites, polyamines, catecholamines, and kynurenines. - [Contact us](https://www.immusmol.com/contact-us/): Contact us Write to our team Please enable JavaScript in your browser to complete this form. Please enable JavaScript in... - [Knowledge base](https://www.immusmol.com/knowledge-base/) - [Cart](https://www.immusmol.com/cart/): You may be interested in... Your cart is currently empty! New in store - [ELISA kits for neurotransmitter quantification](https://www.immusmol.com/shop/elisa-kits-for-neurotransmitter-quantification/): Our range of ELISA kits for neurotransmitter analysis provide a fast, easy-to-use and accurate alternative to HPLC/Mass-Spec approaches for the measurement of neuromediators. Our ultra-sensitive kits are designed to fit any prelinical sample, with a very low minimal sample volume, thus allowing the quantification of neurotransmitter release in cell culture and organoid supernatant, as well as rodent microdyalisates. In addition, we offer a range of fast ELISA kits design for rapid measurements in urine and plasma samples. - [Support Portal](https://www.immusmol.com/support-portal/) - [Login-email](https://www.immusmol.com/login-email/): Enter your email address to join or login - [Password](https://www.immusmol.com/password/): What’s your password ? - [Signup page](https://www.immusmol.com/signup-page/): Welcome! - [Password reset](https://www.immusmol.com/password-reset/): Check your email and enter your new password. Minimum 8 characters Uppercase letters, lowercase letters, and at least one number... - [Immusmol Terms & Conditions](https://www.immusmol.com/immusmol-terms-conditions/): Welcome to Immusmol’s website and thank you for your interest in our company. To use www. immusmol. com and purchase Immusmol... - [Immusmol Terms & Conditions of Use](https://www.immusmol.com/immusmol-terms-conditions-of-use/): Last updated : September 18, 2018 Article 1. Website operator The present terms and conditions of use (“terms” or “conditions”)... - [Terms & Conditions of Sale](https://www.immusmol.com/terms-conditions-of-sale/): Last updated: April 14 ,2018 Article 1 – Definition, scope, and acceptance of terms & conditions The present terms and... - [Immusmol Terms & Conditions of Service](https://www.immusmol.com/immusmol-terms-conditions-of-service/): Last updated: May 19th, 2018 Article 1. Definition, scop,e and acceptance of terms & conditions The present terms and conditions... - [Immusmol Distributors](https://www.immusmol.com/immusmol-distributors/) - [Careers at Immusmol](https://www.immusmol.com/careers-at-immusmol/): We’re a human-size company, which brings together biochemists, cell biologists, immunologists, medical oncologists and data scientists under the same roof (learn about our CRO activity). - [Custom mouse monoclonal antibodies against small molecules](https://www.immusmol.com/custom-small-molecule-antibody-services-anti-hapten-antibodies/custom-mouse-monoclonal-antibodies-against-small-molecules/): Immusmol develops mouse monoclonal antibodies (mAbs) for small molecule detection (amino acid metabolites, lipids, saccharids, toxins, steroids, etc.) by IHC or ELISA. Highly reliable, small molecule mAbs are particularly suited to diagnostic & theranostic applications. - [Custom rabbit polyclonal antibodies against small molecules](https://www.immusmol.com/custom-small-molecule-antibody-services-anti-hapten-antibodies/custom-rabbit-polyclonal-antibodies-against-small-molecules/): Immusmol develops rabbit polyclonal antibodies (pAbs) against any molecule under 900 Daltons: steroids, nucleotides, small molecule drugs, chemical pollutants, pesticide residues, etc. Compatible with ELISA and IHC technologies, our pAbs represent inexpensive and easy-to-implement tools, allowing accurate and robust detection of small molecules in cells, tissues, and biological fluids. - [Credits](https://www.immusmol.com/credits/): Graphics : Immusmol Web design and development : Kipdev. io - [Custom small molecule antibody services](https://www.immusmol.com/custom-small-molecule-antibody-services-anti-hapten-antibodies/): Based on our expertise in antigen design, we design custom small molecule antibodies against a large variety of targets, such as Amino acid metabolites, Lipids, Saccharids, Steroids, Nucleotides, Small molecule drugs, Toxins, Drug residues, Pesticides residues, Chemical pollutants - [Immusmol I Antibodies & ELISA kits for Small Molecules](https://www.immusmol.com/): Immusmol develops antibodies and immunoassays (ELISA & staining kits) to help scientists detect and quantify small molecules. - [Product Category](https://www.immusmol.com/product-category/): Surgical Pharmacy Personal Independent Living - [Return Policy](https://www.immusmol.com/return-policy/): Returns As of March 1, all PPE, disinfectants, and Corona Virus-related products can’t be returned or refunded per our terms... - [Shipping Options](https://www.immusmol.com/shipping-options/): Your choice In the contiguous United States, our standard shipping fee is $19. 99 for all orders $199. 99 and... - [Small Molecule Detection Blog](https://www.immusmol.com/small-molecule-detection-blog-latest-news/): Latest news about Immusmol : new products, publications, upcoming webinars and meetings, and press releases. - [About Immusmol](https://www.immusmol.com/about-immusmol-company/): While traditional antibodies only recognize large molecules such as proteins, Immusmol designs and develops antibodies capable of targeting low molecular weight entities, below 900 Daltons, that can be used for conventional staining applications as well as in the scope of novel immunoassays development - [Purchase Guide](https://www.immusmol.com/purchase-guide/): Accepted Currency All the prices of courses are in US dollars. We mainly accept payments in US dollars, meanwhile other... - [Terms of Service](https://www.immusmol.com/terms-of-service/): Legal Disclaimer Seller hereby expressly disclaims all warranties either expressed or implied warranty of merchantability or fitness for a particular... - [Shop](https://www.immusmol.com/shop/) - [Checkout](https://www.immusmol.com/checkout-2/) - [My account](https://www.immusmol.com/my-account-2/) - [Privacy Policy](https://www.immusmol.com/privacy-policy-2/): We are committed to protect the security and privacy of your data, as a visitor and as a customer. In compliance with French law n°78-17 and its amendments, as well as Regulations (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on the protection of natural persons with regard to the processing of Personal Data and on the free movement of such data, known as the General Data Protection Regulation (GDPR) for users in the European data region, we thus want to ensure you can access, modify or delete any personal information collected by us. --- ## Posts - [New ELISA kit for the Quantification of D-Serine!](https://www.immusmol.com/new-elisa-kit-for-the-quantification-of-d-serine/): Two years after the launch of our L-Serine ELISA kit (already cited in two peer-reviewed publications), our R&D team has... - [Immuno-Oncology: A Practical Toolbox for Quantifying Amino Acid Metabolism](https://www.immusmol.com/immuno-oncology-a-practical-toolbox-for-quantifying-amino-acid-metabolism/): Cancer cells aggressively reprogram amino acid metabolism to sustain their rapid proliferation and survival. By doing so, they deplete the... - [New product: Highly Sensitive Citrulline ELISA kit validated for plasma samples](https://www.immusmol.com/new-product-highly-sensitive-citrulline-elisa-kit-validated-for-plasma-samples/): Just released, our Citrulline ELISA kit completes our range of ELISA kits designed to assess arginine metabolism and nitric oxide... - [Amino acids in brain health & disease: why and how to measure them easily ?](https://www.immusmol.com/amino-acids-in-brain-health-disease-why-and-how-to-measure-them-easily/): Amino acids are critical for brain function. They serve as building blocks for neurotransmitter and protein synthesis, supply energy, detoxify... - [Measuring the Kynurenine to Tryptophan ratio by ELISA: Highlights from our customers’ research](https://www.immusmol.com/measuring-the-kynurenine-to-tryptophan-ratio-by-elisa-highlights-from-our-customers-research/): Ten years ago, we introduced the first research ELISA kits designed to easily measure Kynurenine (Kyn) and Tryptophan (Trp) concentrations... - [New product: Highly sensitive Melatonin ELISA kit for serum and plasma samples](https://www.immusmol.com/new-product-highly-sensitive-melatonin-elisa-kit-for-serum-and-plasma-samples/): Our range of ELISA kits for quantifying tryptophan metabolites welcomes a new addition: Melatonin. This highly sensitive ELISA kit enables... - [WEBINAR on July 17th: Dive into Highly Multiplexed 3D Spatial Biology with the INSIHGT approach.](https://www.immusmol.com/webinar-on-july-17th-dive-into-highly-multiplexed-3d-spatial-biology-with-the-insihgt-approach/): Over the past decade, the team of Hei Ming LAI, MD, at The Chinese University of Hong Kong has developed... - [Serotonin ELISA kits for research applications: a short literature review](https://www.immusmol.com/serotonin-elisa-kits-for-research-applications-a-literature-review/): Anxiety and depression, autism, cognitive decline, gut motility and intestinal inflammation disorders, ... Abnormal serotonin levels are detected in a... - [Dopamine quantification: a webinar on midbrain organoid models of Parkinson's disease](https://www.immusmol.com/dopamine-quantification-a-webinar-on-midbrain-organoid-models-of-parkinsons-disease/): On June 19th, Immusmol hosted a webinar about midbrain organoid models of Parkinson’s disease. Prof. Jens Christian Schwamborn (LCSB /... - [Back from ISTRY 2024 !](https://www.immusmol.com/back-from-istry-2024/): Alban, our CEO, was in Germany on April 24-26th to attend the 16th meeting of the International Society for Tryptophan... - [Imaging neurotransmitters, not enzymes, receptors, or transporters](https://www.immusmol.com/imaging-neurotransmitters-not-enzymes-receptors-or-transporters/): Dopamine, Serotonin, GABA, Glutamate, Histamine, Norepinephrine, Serine, Octopamine, ... To generate spatial information about key neuromodulators and neurotransmitters, neurobiologists typically... - [Beyond TH: Imaging Dopamine Content in Midbrain Organoids for Parkinson’s Disease Modeling](https://www.immusmol.com/beyond-th-imaging-dopamine-content-in-midbrain-organoids-for-parkinsons-disease-modeling/): TH expression does not necessarily indicate that neurons are metabolically active and produce dopamine. Therefore, several groups interested in organoid-based modeling of Parkinson’s disease have combined standard markers of dopaminergic neurons, such as TH and GIRK2, with direct staining of dopamine using anti-hapten antibodies, as well as ELISA kits for quantifying dopamine release in supernatant. - [Reveal serotonin in your samples using our dedicated tools](https://www.immusmol.com/reveal-serotonin-in-your-samples/): Serotonin (5HT) is one of the most potent monoamine neurotransmitters and peripheral signaling molecules. Therefore, tools allowing for the evaluation of serotonergic systems are valuable to approach the complex 5HT activities in physiological and pathological situations, but also to investigate mechanisms of action of novel disease-targeting therapies. For this purpose, we have set up and validated a series of experimental immunoassays specifically raised against 5HT. - [Assessing the polyamine pathway through immunoassays!](https://www.immusmol.com/assessing-the-polyamine-pathway-through-immunoassays/): Polyamines are molecules derived from ornithine (putrescine, spermine, spermidine, etc.) or arginine (agmatine, etc.). Given the importance of polyamine metabolism in cancer progression and resistance to treatment, robust tools are needed to investigate this pathway. To this aim, we developed and validated the first ELISA kits able to quantify ornithine, N1-acetylspermidine and N8-acetylspermidine in samples of different natures (plasma, cell culture supernatants) and different species (mouse, human). - [A newcomer to our antibodies portfolio for Serotonin imaging on FFPE samples](https://www.immusmol.com/a-newcomer-to-our-antibodies-portfolio-for-serotonin-imaging-on-ffpe-samples/): Serotonin (5-HT) is one of the most potent monoamine neurotransmitters and peripheral signaling molecules. Physiologically, 5-HT has complex and diverse effects on the central and peripheral nervous systems, neuroendocrine regulation, and immunological responses. We recently developed and added to our catalog a novel antibody raised against 5-HT, compatible with formalin-fixed biological materials. - [Assessing Arginase activity through an easy-to-use immunoassay now possible!](https://www.immusmol.com/assessing-arginase-activity-through-an-easy-to-use-immuno-assay-now-possible/): Given the importance of the Arginase pathway in pathophysiological processes, we have developed and validated a robust and easy-to-use immunoassay for the simultaneous detection and quantification of both L-Arginine and L-Ornithine in plasma / serum - [Quantification of L-Arginine in various samples made simple!](https://www.immusmol.com/quantification-of-l-arginine-in-various-samples-made-simple/): L-Arginine is a key amino acid in the immune regulation and can be targeted as part of an anti-tumor response.... - [Antibodies to neurotransmitters as tools to evaluate the transmission network/function by immunofluorescence](https://www.immusmol.com/antibodies-to-neurotransmitters-as-tools-to-evaluate-the-transmission-network-function-by-immunofluorescence/): Glutamate (Glu) and gamma-aminobutyric acid (GABA) are the major neurotransmitters (NTs) in the brain and work together through balanced interactions... - [L-Histidine, a newcomer to our ELISA kits portfolio!](https://www.immusmol.com/l-histidine-a-newcomer-to-our-elisa-kits-portfolio/): We developed and validated a new L-Histidine ELISA kit (#IS-I-1300R) which allows for L-His quantitation in plasma samples. The assay... - [Plasma L-Arginine levels assessed by ELISA predict response of cancer patients to immune checkpoint blockers](https://www.immusmol.com/spotlight-from-annals-of-oncology/): New highlight in Annals of Oncology! In this study, Peyraud at al. show that plasmatic level of L-Arginine (Arg) is... - [Comprehensive and easy-to-access evaluation of the Kynurenine pathway by ELISA!](https://www.immusmol.com/get-a-comprehensive-and-easy-to-access-evaluation-of-the-kynurenine-pathway-by-elisa/): Among mechanisms associated with cancer immune evasion, the activation of the Kynurenine Pathway (KP) is known to play a key... - [New arrival in our Amino Acid ELISA kits portfolio! L-Asparagine quantification made easy](https://www.immusmol.com/new-arrival-in-our-amino-acid-elisa-kits-portfolio-l-asparagine-quantification-made-easy/): We developed and validated a new L-Asparagine ELISA kit (#IS-I-1600R) which allows for L-Asn quantitation in plasma samples. The assay... - [Kynurenine / Tryptophan ELISA pack recently cited in Cancer Discovery](https://www.immusmol.com/126-news-kynurenine-tryptophan-elisa-pack-recently-cited-in-cancer-discovery-html/): Our Kynurenine/Tryptophan ELISA pack recently cited in Cancer Discovery in a publication written by Marta Galan-Diez et al. In this... - [ImmuSmol products trusted by scientists and highlighted in recent publications!](https://www.immusmol.com/124-news-immusmol-products-trusted-by-scientists-and-highlighted-in-recent-publications-html/): ImmuSmol products trusted by scientists and highlighted in recent publications! Discover the recent studies where some of our top products... - [Serum or Plasma samples? it matters for Amino Acid levels!](https://www.immusmol.com/123-news-sera-or-plasma-samples-it-matters-for-amino-acid-levels-html/): Using our ELISA kits, we quantified several amino acids in matched plasma-serum samples. The results highlights the importance of the... - [Our products increasingly referenced in 2021!](https://www.immusmol.com/122-news-our-products-increasingly-referenced-in-2021-html/): Discover the scientific publications written in 2021 that cite Immusmol products! Antibodies, STAINperfect and ELISA kits were used and referenced... - [L-Serine quantification by ELISA? It's now possible!](https://www.immusmol.com/118-news-l-serine-quantification-by-elisa-now-possible-html/): We developed and validated a newSerine ELISA kit (#IS-I-1200) which allows for L-Ser quantitation in biological samples including plasma, sera... - [New L-Glutamine ELISA as tool to address metabolic features in cell culture supernatants](https://www.immusmol.com/116-news-elisa-based-quantification-of-glutamine-cancer-cell-lines-html/): Glutamine metabolism is an attractive therapeutic path in immuno-oncology. Glutamine level should rely mainly on Glutamine quantification, which can now... - [Arginine level by ELISA as a surrogate for Arginase activity](https://www.immusmol.com/115-news-arginine-level-by-elisa-as-a-surrogate-for-arginase-activity-html/): New therapeutic options in immuno-oncology consist in manipulating metabolic pathways. Whatever the mechanism of action of drug candidates Arginine remains... - [Validated antibodies cited in many recent publications](https://www.immusmol.com/114-news-neurotransmitter-imaging-validated-antibodies-cited-in-many-recent-publications-html/): We have set up and validated a series of antibodies targeting key neurotransmitters, including among others dopamine, serotonin, glutamate, noradrenaline.... - [Our products increasingly referenced!](https://www.immusmol.com/111-news-our-products-increasingly-cited-html/): Our products were hilighted in 2020 in these scientific publication. Antibodies, STAINperfect and ELISA kits were used and referenced. - [Identification of IDO modulators using Kynurenine & Tryptophan as surrogate markers](https://www.immusmol.com/108-news-kynurenine-tryptophan-as-surrogate-markers-for-innovative-ido-modulators-screening-html/): Novel therapeutic options in immuno-oncology consist in manipulating – directly or indirectly - metabolic pathways such as the one of... - [Newly-released ELISA kit for Arginine (ARG)!](https://www.immusmol.com/107-news-newly-released-elisa-kit-for-arginine-arg-html/): Arginine (ARG) is a basic non-essential amino acid well known to participate in physiological functions such as i) vascular tone... - [Newly-released ELISA pack for Kynurenic / Quinolinic Acids](https://www.immusmol.com/106-news-newly-released-elisa-pack-for-kynurenic-quinolinic-acids-html/): Through the degradation of L-Tryptophan, the Kynurenine pathway (KP) generates a series of catabolites collectively known as Kynurenines, which can... - [Homoarginine (hARG) ELISA kit out now!](https://www.immusmol.com/105-news-homoarginine-harg-elisa-kit-out-now-html/): HomoArginine (hArg) is a basic non-essential amino acid that exerts beneficial effects on vascular homeostasis, more likely through the increase... - [New ELISA Kit out now for Kynurenic Acid!](https://www.immusmol.com/101-news-new-elisa-kit-out-now-for-kynurenic-acid-html/): New ELISA Kit out now for Kynurenic Acid! - [Reveal Dopamine in your samples using our dedicated tools](https://www.immusmol.com/100-blog-reveal-dopamine-in-your-samples-using-our-dedicated-tools-html/): Reveal Dopamine in your samples using our dedicated tools - [Dopamine antibody: Imaging dopaminergic neurons of the Substantia Nigra pars compacta (SNc) in coronal rat brain sections](https://www.immusmol.com/98-blog-take-the-opportunity-of-a-special-offer-to-try-our-dopamine-ab-html/): Take the opportunity of a special offer to try our Dopamine Ab - [Quinolinic Acid ELISA kit: NOW OUT!](https://www.immusmol.com/93-blog-quinolinic-acid-elisa-kit-now-out-html/): Quinolinic Acid ELISA kit: NOW OUT! 96-w plate format / Low volume samples / Sensitive, easy-to-implement / Cross-validated with LC/MS - [Kynurenine and tryptophan as surrogate immune suppression tumor biomarkers](https://www.immusmol.com/90-blog-versatile-quantification-of-kynurenine-tryptophan-levels-by-elisa-html/): Kynurenine and tryptophan as surrogate immune suppression tumor biomarkers - [Validated monoclonal anti-GABA antibody to evaluate GABAergic system network/function by immunofluorescence](https://www.immusmol.com/87-blog-validated-monoclonal-antibody-to-assess-gaba-by-immunofluorescence-if-and-immunohistochemistry-ihc-html/): Validated monoclonal anti-GABA antibody to evaluate GABAergic system network/function by immunofluorescence - [Validated antibody to assess L-Kynurenine by IHC](https://www.immusmol.com/86-blog-validated-antibody-to-assess-l-kynurenine-by-ihc-html/): Validated antibody to assess L-Kynurenine by IHC - [Kynurenine levels measured by ELISA](https://www.immusmol.com/84-blog-kynurenine-levels-measured-by-elisa-html/): Kynurenine levels measured by ELISA - Special offer - [Effect of IDO1 inhibition on  Kynurenine levels measured by ELISA](https://www.immusmol.com/82-blog-effect-of-ido1-inhibition-on-kynurenine-levels-measured-by-elisa-html/): Effect of IDO1 inhibition on Kynurenine levels measured by ELISA - [Quantitative analysis of neurite outgrowth using IS1006 GABA antibody](https://www.immusmol.com/quantitative-analysis-of-neurite-outgrowth-using-is1006-gaba-antibody/): Quantitative analysis of neurite outgrowth using IS1006 GABA antibody - [ImmuSmol highlighted in two recent scientific publications!](https://www.immusmol.com/70-blog-immusmol-highlighted-in-two-recent-scientific-publications-html/): ImmuSmol's antibodies targeting small molecules, such as the neurotoxic amino-acid BMAA, were used and highlighted in two recent publications. - [Meet us at the NEUROFRANCE 2017 in Bordeaux](https://www.immusmol.com/69-blog-meet-us-at-the-neurofrance-2017-in-bordeaux-html/): Meet us at the NEUROFRANCE 2017 in Bordeaux - [New antibody for Noradrenaline now available using STAINperfect immunostaining kit](https://www.immusmol.com/66-blog-new-antibody-for-noradrenaline-now-available-using-stainperfect-immunostaining-kit-html/): New antibody for Noradrenaline now available using STAINperfect immunostaining kit - [Challenge Serotonin and its precursor L-Tryptophan using STAINperfect immunostaining kit](https://www.immusmol.com/65-blog-challenge-serotonin-and-its-precursor-l-tryptophan-using-stainperfect-immunostaining-kit-html/): Challenge Serotonin and its precursor L-Tryptophan using STAINperfect immunostaining kit - [Get access to the Dopamine and Serotonin crosstalk using STAINperfect immunostaining kit](https://www.immusmol.com/64-blog-get-access-to-the-dopamine-and-serotonin-crosstalk-using-stainperfect-immunostaining-kit-html/): Get access to the Dopamine and Serotonin crosstalk using STAINperfect immunostaining kit - [Launch of Explicyte Immuno-Oncology!](https://www.immusmol.com/63-blog-launch-of-explicyte-immuno-oncology-html/): ImmuSmol is launching Explicyte Immuno-Oncology: a brand-new range of preclinical services in the field of cancer immunotherapy. - [Neurotransmitter imaging: Differential organization of two key neurotransmitters within ne ...](https://www.immusmol.com/62-blog-neurotransmitter-imaging-differential-organization-of-two-key-neurotransmitters-within-neurons-revealed-by-stainperfect-kit-html/): Neurotransmitter imaging: Differential organization of two key neurotransmitters within neurons revealed by STAINperfect kit - [Neurotransmitter imaging protocols: Standard procedure versus STAINperfect immunostaining ...](https://www.immusmol.com/neurotransmitter-imaging-protocols-standard-procedure-versus-stainperfect-immunostaining-kit-html/): Why using the STAINperfect immunostaining kit ? We compared the standard immunostaining procedure to the optimized STAINperfect protocol for cell... - [The L-Kynurenine ELISA: A cell-based assay to screen IDO/TDO inhibitors](https://www.immusmol.com/ido-tdo-inhibitor-screening-cell-based-assay-l-kynurenine-elisa-html/): Our L-Kynurenine ELISA can be used to screen IDO/TDO inhibitors in cell lines. See our data with IDO inhibitor 1-Methyl-L-Tryptophan. - [PICTURE OF THE WEEK: L-Glutamate in crayfish brain](https://www.immusmol.com/l-glutamate-antibody-staining-brain-crayfish-html/): L-Glutamate antibody highlights the presence of glutamatergic cells in a crayfish brain. - [PICTURE OF THE WEEK: Serotonin in primary mesencephalic cells](https://www.immusmol.com/5-ht-serotonin-antibody-primary-cell-culture-rat-html/): Serotonin antibody combined with STAINperfect immunostaining kit highlights the presence of Serotonin (in green) in rat primary mesencephalic cells (in... - [PICTURE OF THE WEEK: Dopamine staining in embryonic mouse brain](https://www.immusmol.com/dopamine-staining-in-embryonic-mouse-brain-html/): Dopamine antibody combined with STAINperfect immunostaining kit highlights dopaminergic fibers in embryonic mouse brain (E13. 5) - [ISTRY 2015 : Congratulations to the winners of our quizz](https://www.immusmol.com/istry-2015-congratulations-to-the-winners-of-our-quizz/): Back from the 2015 ISTRY conference, we would like to thanks the organizers for this fruitful event and congratulate the... - [ImmuSmol sponsors the 2015 ISTRY conference](https://www.immusmol.com/istry-2015-conference-immusmol-congratulations-winners-quizz-html/): ImmuSmol is sponsoring the 2015 conference of the International Society for Tryptophan Research, taking place on September 16-18, at the... - [New article! Characterization of Kynurenine pathway in human obesity](https://www.immusmol.com/the-kynurenine-pathway-is-activated-in-human-obesity-html/): ImmuSmol CEO Alban Bessede has contributed to a recent paper in Obesity : "The kynurenine pathway is activated in human... - [L-Kynurenine monoclonal antibody in PLOS ONE](https://www.immusmol.com/l-kynurenine-monoclonal-antibody-cancer-ido1-plos-one-html/): A recent PLOS ONE article shows that ImmuSmol's anti-L-Kynurenine-antibody can serve to stratify cancer patients for kynurenine pathway activity. Access... - [The immune-brain axis: from molecules to behavior](https://www.immusmol.com/immune-brain-axis-from-molecules-to-behavior-html/): ImmuSmol is sponsoring the Symposium "The immune-brain axis: from molecules to behavior", held at the Hasselt University, Campus Diepenbeek, Belgium,... - [ImmuSmol's Small Molecule Antibodies in the Press](https://www.immusmol.com/immusmol-small-molecule-antibodies-highlighted-in-press-html/): Discover ImmuSmol's story, featured in the 2015 winter edition of the European Biotechnology Magazine. - [ImmuSmol raises 500 000 € to advance cancer immunotherapy programme](https://www.immusmol.com/immusmol-raises-500-000-for-cancer-immunotherapy-in-vivo-proof-of-concept-html/): ImmuSmol is pleased to announce it has raised 500 000 € to progress its monoclonal antibodies for cancer immunotherapy to... - [Nature Article](https://www.immusmol.com/nature-article-alban-bessede-html/): Access latest article by ImmuSmol CEO Alban Bessède - [Polyclonal antibodies to TRP/KYN metabolites](https://www.immusmol.com/polyclonal-antibodies-to-tryptophan-kynurenine-metabolites-rabbit-pab-ihc-validated-html/): NEW! ImmuSmol releases rabbit polyclonal antibodies against Tryptophan / Kynurenine metabolites, all validated for IHC in human samples. Picture: L-Kynurenine... - [Antibodies against small molecules](https://www.immusmol.com/antibodies-against-small-molecules-html/): A short overview of ImmuSmol's services for the development of antibodies against small molecules, and their subsequent validation for small... - [Small molecule detection](https://www.immusmol.com/small-molecule-detection-antibodies-html/): Small molecule antibodies constitute a powerful alternative to mass spec and aptamer-based technologies for small molecule detection, building on the... - [Anti-hapten antibodies](https://www.immusmol.com/anti-hapten-antibodies-small-molecule-detection-html/): Anti-hapten antibodies enable the detection of small molecules using robust and rapid immunodetection technologies, such as ELISA and IHC/IF. Either raised against endogenous small molecules (amino acid metabolites, lipids, saccharids, nucleotides, steroids, ...) or exogenous compounds (drug and pesticide residues, chemical pollutants,...), anti-hapten antibodies constitute attractive detection tools in the field of human health, for diagnostic and theranostic applications, but also in areas such as food safety and environmental monitoring. --- ## Products - [L-Threonine Antibody- Rabbit Polyclonal](https://www.immusmol.com/product/l-threonine-antibody-rabbit-polyclonal/): The anti-L-Threonine antibody IS1078 allows the detection of the proteinogenic amino acid L-Threonine in biological samples. Our team demonstrated the affinity and specificity of this polyclonal antibody, and we're currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. - [L-Leucine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-leucine-antibody-rabbit-polyclonal/): The anti-L-Leucine antibody IS1076 enables the detection of the essential amino acid L-Leucine in biological samples. Our team has validated the affinity and specificity of this polyclonal antibody. Compatible with STAINperfect immunostaining kit A, the antibody can be used for IF/ICC/IHC imaging applications. - [L-Alanine Antibody- Rabbit Polyclonal](https://www.immusmol.com/product/l-alanine-antibody-rabbit-polyclonal/): Highly affine and specific, the anti-L-Alanine antibody IS1075 enables the detection of non-essential amino acid α-alanine in biological samples. Combined with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody can stain L-Alanine in cells and tissues (IF/ICC/IHC protocols available). - [3-Hydroxykynurenine antibody - Rabbit Polyclonal](https://www.immusmol.com/product/3-hydroxykynurenine-antibody-rabbit-polyclonal/): The anti-3-Hydroxykynurenine antibody IS1083 allows the detection of neurotoxic kynurenine metabolite 3-HK in biological samples. Our team developed and cross-validated by LC-MS an ELISA kit for 3-HK, based on this antibody. We're currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. - [L-Tryptophan antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-tryptophan-antibody-rabbit-polyclonal/): The anti-L-Tryptophan antibody IS1069 enables the detection of L-Tryptophan in biological samples. This rabbit polyclonal antibody can be combined with our range of mouse monoclonal antibodies to tryptophan downstream metabolites for multiplexed imaging. Requiring the use of the STAINperfect immunostaining kit A, the antibody is supplied with ready-to-use protocols for IF, ICC, and IHC applications. - [3-Hydroxy-Kynurenine ELISA kit](https://www.immusmol.com/product/3-hydroxy-kynurenine-elisa-kit/): The 3-Hydroxy-Kynurenine (3-HK) ELISA Kit provides a simple, highly sensitive method for quantifying 3-HK in just 50 µL of plasma from any species. - [D-Serine ELISA kit](https://www.immusmol.com/product/d-serine-elisa-kit-plasma-serum-supernatant/): The D-Serine ELISA Kit enables the easy and sensitive quantification of D-Serine (D-Ser) in plasma, serum, cerebrospinal fluid (CSF), and cell culture supernatants. Validated in human plasma samples, the assay requires only 50 μL of sample, making it suitable for both in vitro, preclinical, and clinical research applications. This kit is particularly relevant for studies investigating neurological disorders related to NMDA receptor and glutamatergic pathway dysfunctions, as well as for research into chronic kidney disease. - [Fast Histamine Tests (ELISA) - Any Fish Sample - HistaSure™ XL](https://www.immusmol.com/product/fast-histamine-elisa-kit-histasure-xl/): Our XL ELISA pack of fast histamine tests for fish (fresh or frozen) and fish-derived products (canned fish, fish meal, etc.) allows the determination of histamine levels in 480 fish samples. Validated and certified by the AOAC Research Institute, our rapid assays can detect histamine levels between 0.44ppm and 300ppm within 25 minutes. - [STAINperfect™ - Trial pack](https://www.immusmol.com/product/stainperfect-trial-pack/): Test the STAINperfect™ immunostaining kit in combination with 2 primary antibodies targeting neurotransmitters, amino acids, kynurenines, catecholamines, polyamines, etc... - [L-Histidine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-histidine-antibody-rabbit-polyclonal/): Highly affine and specific, the IS1066 anti-L-Histidine antibody can be used with the STAINperfect immunostaining kit A to perform ICC/IHC/IF stainings in cell cultures, whole mounts and tissue sections. - [L-Citrulline Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-citrulline-antibody-rabbit-polyclonal/): This anti-L-Citrulline antibody can be used in combination with the STAINperfect immunostaining kit A to visualize L-Citrulline in various types of samples (cell culture, tissue...). - [L-Lysine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-lysine-antibody-rabbit-polyclonal/): This anti-L-Lysine antibody is the first and only antibody to date for the detection of L-Lysine (LYS) in biological samples. Used with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody can stain for L-Lysine in various types of samples (cell culture, tissue...). - [N1-Acetyl-Spermidine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/n1-acetyl-spermidine-antibody-rabbit-polyclonal/): The anti-N1-Acetyl-Spermidine antibody IS1070 is, to date, the first and only antibody that enables the detection of this acetylated derivative of spermidine in biological samples. When used in conjunction with the STAINperfect Immunostaining Kit A, this rabbit polyclonal primary antibody can enable N1-Acetylspermidine imaging in various sample types, including cell cultures and tissues. - [N8-Acetyl-Spermidine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/n8-acetyl-spermidine-antibody-rabbit-polyclonal/): The anti-N8-Acetyl-Spermidine antibody IS071 is the first and only antibody for the detection of the polyamine N8AS, derived from spermidine. Combined with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody can allow direct N8-Acetylspermidine visualization in various types of samples (cell culture, tissue...). - [Serotonin Antibody for FFPE samples - Rabbit Polyclonal](https://www.immusmol.com/product/serotonin-antibody-for-ffpe-samples-rabbit-polyclonal/): This 5-HT antibody was valided on formalin-fixed paraffin-embedded (FFPE) specimens and used for immunochemistry and immunofluorescence applications. - [Pregnenolone ELISA kit - Serum Samples](https://www.immusmol.com/product/pregnenolone-elisa-kit-i-fast-i-serum-samples/): This Pregnenolone ELISA kit is designed for the quantitative measurement of the endogenous steroid pregnenolone in human serum samples. As a crucial downstream product of cholesterol metabolism, pregnenolone is instrumental in confirming the activity of CYP11A1 and 3β-HSD enzymes in both the gonads and adrenal glands. Accurate measurement of pregnenolone can therefore assist in identifying adrenal function disorders, such as congenital adrenal hyperplasia, endocrine tumors, and infertility. Moreover, because pregnenolone is a key precursor in the steroid hormone biosynthesis pathway, this kit is also well-suited for monitoring steroidogenesis—for example, in studies evaluating the impact of endocrine-disrupting chemicals (EDCs). - [Testosterone ELISA kit - Human Saliva](https://www.immusmol.com/product/testosterone-elisa-kit-i-fast-i-human-saliva/): This ELISA kit enables quantitative measurement of testosterone in human saliva samples. It can be used to assess endocrine function, reproductive health, and hormonal variations in behavioral or metabolic studies. Designed for both in vitro diagnostic and research applications, the non-invasive saliva-based assay is provided in a 96-well plate format, allowing for high-throughput testing and efficient turnaround times. - [DHEA-S ELISA kit - Human Saliva](https://www.immusmol.com/product/dhea-s-elisa-kit-i-fast-i-human-saliva/): This DHEA-S ELISA kit provides quantitative measurement of Dehydroepiandrosterone sulfate (DHEA-S) in human saliva samples, supporting the assessment of reproductive health and adrenal function. Suitable for both in vitro diagnostic and research applications, the non-invasive saliva-based assay is offered in a 96-well plate format, enabling high-throughput testing and streamlined turnaround times. - [DHEA ELISA kit - Human Saliva](https://www.immusmol.com/product/dhea-elisa-kit-i-fast-i-human-saliva/): This DHEA ELISA kit provides a quantitative method for measuring Dehydroepiandrosterone (DHEA) in human saliva, facilitating the evaluation of adrenal function and hormonal imbalances in reproductive, metabolic, and endocrine contexts. Designed for both in vitro diagnostic and research use, this non-invasive, saliva-based assay is provided in a 96-well plate format, supporting high-throughput testing and efficient turnaround times. - [Androstenedione ELISA kit - Human Saliva](https://www.immusmol.com/product/androstenedione-elisa-kit-i-fast-i-human-saliva/): This Androstenedione ELISA kit enables quantitative measurement of androstenedione in human saliva, supporting the evaluation of adrenal and gonadal function, as well as the monitoring of hormonal disorders such as polycystic ovary syndrome (PCOS) and hirsutism. Suitable for both in vitro diagnostic and research applications, it uses a non-invasive saliva-based format and comes in a 96-well plate, allowing for high-throughput testing and efficient turnaround times. - [Chromogranin A ELISA (CgA) - Serum Samples](https://www.immusmol.com/product/chromogranin-a-elisa-i-serum-samples/): The Chromogranin A ELISA kit delivers a straightforward, reliable method for quantifying CgA levels in serum samples, facilitating both the diagnosis and therapeutic monitoring of neuroendocrine tumors (NET)—including carcinoid tumors and pancreatic NETs. Beyond oncology, it also serves as a valuable tool in research on cardiovascular diseases and inflammatory disorders. With excellent correlation to Kryptor CgA II and proven diagnostic performance for GEP-NET, this assay supports rapid, high-precision screening for enhanced patient management and scientific investigation. - [Progesterone ELISA kit - Saliva](https://www.immusmol.com/product/progesterone-elisa-kit-fast-saliva/): This ELISA kit enables the measurement of progesterone levels in saliva, which increase significantly after ovulation. Highly relevant for fertility studies, this immunoassay can also be used to monitor early pregnancy, evaluate progesterone-based hormone therapies, and investigate endocrine disorders as well as stress-hormone interactions. Based on a 96-well plate format and offering a non-invasive sampling method, this rapid assay allows for longitudinal progesterone monitoring. - [Progesterone ELISA kit - Serum and Plasma](https://www.immusmol.com/product/progesterone-elisa-kit-i-fast-i-serum-and-plasma/): This ELISA kit enables the measurement of progesterone levels in serum and plasma samples. Progesterone measurement is widely used to confirm ovulation, monitor high-risk pregnancies, and evaluate hormone replacement therapy and IVF protocols. Beyond fertility and reproduction, this progesterone ELISA kit can also be used in the diagnosis of adrenal disorders and hormone-secreting tumors. - [Aldosterone ELISA kit - Human Serum, Plasma, Urine](https://www.immusmol.com/product/aldosterone-elisa-kit-i-fast-i-human-serum-plasma-urine/): This ELISA kit quantitatively measures aldosterone, a mineralocorticoid hormone that regulates blood pressure and electrolyte balance, in human serum, plasma, and urine samples. The kit is relevant to assess endocrine function, renal physiology, and cardiovascular disorders. Designed for both in vitro diagnostic and research use, its 96-well plate format facilitates high-throughput testing and ensures fast turnaround times. - [Corticosterone ELISA kit - Serum and Plasma](https://www.immusmol.com/product/corticosterone-elisa-kit-i-fast-i-serum-and-plasma/): This ELISA kit enables the quantitative measurement of corticosterone in animal plasma and serum samples. Similar to cortisol in humans, corticosterone is a key stress hormone used to assess stress in animal models. Designed for both in vitro diagnostic and research use, its 96-well plate format facilitates high-throughput testing and ensures fast turnaround times. - [25-OH Vitamin D ELISA kit I Fast I Serum and Plasma](https://www.immusmol.com/product/25-oh-vitamin-d-elisa-kit-i-fast-i-serum-and-plasma/): This 25-OH Vitamin D ELISA kit allows for the precise quantification of 25-hydroxyvitamin D in both plasma and serum samples. 25-OH Vitamin D, which is synthesized in the liver from vitamin D, is crucial for evaluating vitamin D deficiency, affecting bone health, immune function, and muscle function. The kit is suitable for both in vitro diagnostic and research purposes, featuring a 96-well plate format that supports high-throughput testing and ensures rapid results. - [17-OH-Progesterone ELISA kit - Human Serum and Plasma](https://www.immusmol.com/product/17-oh-progesterone-elisa-kit-i-fast-i-human-serum-and-plasma/): This 17-OH-Progesterone (17-OHP) ELISA kit enables the measurement of 17-hydroxyprogesterone in serum or plasma samples. As a precursor to cortisol and sex steroids, 17-OHP is typically measured to assess adrenal function and related disorders, such as hormonal imbalances and adrenal tumors. The kit is suitable for both in vitro diagnostic and research purposes, featuring a 96-well plate format that supports high-throughput testing and ensures rapid results. - [17-OH-Progesterone ELISA kit - Saliva](https://www.immusmol.com/product/17-oh-progesterone-elisa-kit-i-fast-i-saliva/): This 17-OH-Progesterone (17-OHP) ELISA kit enables the measurement of active free 17-α-hydroxyprogesterone in saliva. As a precursor to cortisol and sex steroids, 17-OHP is commonly measured to evaluate adrenal function and associated conditions, including hormonal imbalances and adrenal tumors. The kit is designed for both in vitro diagnostic use and research applications, offering a 96-well plate format that facilitates high-throughput testing and delivers quick results. - [Estradiol ELISA kit I Human Saliva](https://www.immusmol.com/product/estradiol-elisa-kit-human-saliva/): This ELISA kit is designed to measure free estradiol levels in human saliva, supporting both research and diagnostic efforts in areas such as menstrual cycle monitoring, pregnancy assessment, menopause evaluation, endocrine disorder investigation, and the study of hormone-dependent cancers. - [Free Estriol ELISA kit - Serum](https://www.immusmol.com/product/free-estriol-elisa-kit-fast-serum/): This Free Estriol ELISA Kit enables precise measurement of unconjugated estriol (E3) in serum samples. Determining estriol levels is relevant for monitoring fetal development and placental function, assessing gynecological and menopausal health, and characterizing estrogen metabolism. Suitable for both in vitro diagnostic and research applications, this rapid ELISA is provided in a 96-well plate format for fast turnaround times. - [Estrone ELISA kit - Serum and Plasma](https://www.immusmol.com/product/estrone-elisa-kit-i-fast-i-serum-and-plasma/): This Estrone ELISA kit provides accurate quantification of Estrone (E1) in serum and plasma. Measuring estrone is vital for evaluating postmenopausal estrogen levels, monitoring hormone replacement therapy (HRT), detecting estrogen-producing tumors, and investigating endocrine disorders. Suitable for both in vitro diagnostic and research applications, this rapid assay is supplied in a 96-well plate format to ensure fast turnaround times. - [Estrone ELISA kit I Fast I Saliva](https://www.immusmol.com/product/estrone-elisa-kit-i-fast-i-saliva/): This Estrone ELISA kit offers precise measurement of Estrone (E1) in saliva. Monitoring estrone levels is key for evaluating postmenopausal estrogen status, overseeing hormone replacement therapy (HRT), identifying estrogen-secreting tumors, and examining endocrine dysfunctions. Provided in a 96-well plate format, this rapid assay supports both in vitro diagnostic and research uses, ensuring swift turnaround times. - [Cortisol ELISA kit - Serum and Plasma](https://www.immusmol.com/product/cortisol-elisa-kit-i-fast-i-serum-and-plasma/): This rapid ELISA kit quantitatively measures cortisol, the primary glucocorticoid in humans, in serum and plasma samples. Measuring stress hormone cortisol is crucial for assessing endocrine function (HPA axis), stress response, circadian rhythm, and disorders related to adrenal insufficiency. Designed for both in vitro diagnostic and research use, its 96-well plate format facilitates high-throughput testing and ensures fast turnaround times. - [Cortisol ELISA kit - Human urine](https://www.immusmol.com/product/cortisol-elisa-kit-fast-urine/): This rapid ELISA kit is designed to quantitatively measure cortisol, a crucial stress hormone, in human urine (for adults). Measuring cortisol is essential for evaluating psychiatric disorders such as stress, depression, and anxiety, as well as sleep disorders and endocrine diseases. Suitable for both in vitro diagnostic and research purposes, the kit's 96-well plate format enables high-throughput testing and ensures quick results. - [Cortisol ELISA kit - Human Saliva](https://www.immusmol.com/product/cortisol-elisa-kit-i-fast-i-human-saliva/): This ELISA kit is designed for quick and precise measurement of cortisol, a vital stress hormone, in human saliva. The determination of cortisol concentrations is relevant to assess stress levels and explore endocrine and metabolic disorders linked to the HPA axis. Suitable for both diagnostic and research use, this kit comes with a 96-well plate format, enabling efficient high-throughput testing and providing fast results. - [Estradiol ELISA kit - Serum and Plasma](https://www.immusmol.com/product/estradiol-elisa-kit-fast-serum-and-plasma/): This ELISA kit is designed to measure estradiol levels in serum and plasma samples, aiding research into menstrual cycles, pregnancy, menopause, endocrine disorders, and hormone-dependent cancers. Suitable for both in vitro diagnostic and research applications, its 96-well plate format facilitates high-throughput testing and rapid results. - [DHEA ELISA kit - Human Serum and Plasma](https://www.immusmol.com/product/dhea-elisa-kit-i-fast-i-serum-and-plasma-samples/): This DHEA ELISA kit provides quantitative measurement of Dehydroepiandrosterone (DHEA) in human serum and plasma, enabling the assessment of adrenal function and hormonal imbalances in reproductive, metabolic, and endocrine conditions. Designed for in vitro diagnostic and research applications, its 96-well plate format supports high-throughput screening and quick turnaround times for large-scale studies. - [Free Testosterone ELISA kit - Human Serum](https://www.immusmol.com/product/free-testosterone-elisa-kit-i-fast-i-serum/): This Free Testosterone ELISA kit quantitatively measures unbound testosterone in serum, offering insights into androgen metabolism in conditions such as hypogonadism and hyperandrogenism. Developed for both in vitro diagnostic and research use, its 96-well plate format supports high-throughput testing and fast turnaround times. - [DHT ELISA kit - Human Serum](https://www.immusmol.com/product/dht-elisa-kit-i-fast-i-human-serum/): This DHT ELISA kit quantitatively measures Dihydrotestosterone in human serum, offering insights into androgen-driven conditions, such as prostate disorders, acne, and alopecia. Developed for both in vitro diagnostic and research use, its 96-well plate format supports high-throughput testing and fast turnaround times. - [DHEA-S ELISA kit - Human serum](https://www.immusmol.com/product/dhea-s-elisa-kit-fast-serum-samples/): This DHEA-S ELISA kit enables the quantitative measurement of steroid hormone Dehydroepiandrosterone sulfate in human serum samples to evaluate reproductive health and adrenal function. Intended for in vitro diagnostics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. - [Testosterone ELISA kit - Serum & plasma](https://www.immusmol.com/product/testosterone-elisa-kit-fast-serum-plasma-samples/): This ELISA kit enables the quantitative measurement of Testosterone in serum and plasma samples to evaluate endocrine functions, reproductive health, and in the context of behavioral and metabolic conditions. Intended for in vitro diagnostics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. - [Androstanediol-Glucuronide ELISA kit - Human Serum](https://www.immusmol.com/product/androstanediol-glucuronide-elisa-kit-i-fast-i-serum/): This Androstanediol-Glucuronide ELISA kit enables the quantitative measurement of C19 steroid 3α-Diol-G in human serum samples to evaluate androgen metabolism. Intended for in vitro diagnostics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. - [FT3 ELISA kit - Serum](https://www.immusmol.com/product/ft3-elisa-kit-fast-serum/): This FT3 ELISA kit is intended for the quantitative determination of Free Triiodothyronine (FT3) in serum, primarily for assessing thyroid function. Designed for both in vitro diagnostic purposes and research applications, this efficient and reliable assay (75 minutes) utilizes a 96-well plate format, making it ideal for high-throughput screening with quick turnaround times. - [FT4 ELISA kit - Serum](https://www.immusmol.com/product/ft4-elisa-kit-fast-serum/): This FT4 ELISA kit is designed for the quantitative measurement of Free Thyroxine (FT4) in serum, primarily to evaluate thyroid function. Suitable for both in vitro diagnostic applications and research purposes, this reliable and efficient assay (75 minutes) features a 96-well plate format, making it optimal for high-throughput screening with fast turnaround times. - [TSH ELISA kit - Serum & Plasma](https://www.immusmol.com/product/tsh-elisa-kit-fast-serum-plasma/): This TSH ELISA kit is designed for the quantitative measurement of thyrotropin (TSH) in serum and heparin-plasma samples, primarily to evaluate thyroid gland function. Suitable for both in vitro diagnostic use and research applications, this fast and reliable assay (120 minutes) employs a 96-well plate format, making it well-suited for high-throughput screening with rapid turnaround times. - [Reverse T3 (rT3) ELISA kit - Serum & Plasma](https://www.immusmol.com/product/reverse-t3-rt3-elisa-kit-fast-serum-plasma/): This Reverse T3 ELISA kit is intended for the quantitative measurement of reverse Triiodothyronine (rT3) in serum and plasma samples (EDTA, lithium heparin, or citrate) to assess thyroid function. Designed for both in vitro diagnostic and research applications, this fast and reliable assay (105 minutes) utilizes a 96-well plate format, making it ideal for high-throughput screening with quick turnaround times. - [T4 ELISA kit - Serum & Plasma](https://www.immusmol.com/product/t4-elisa-kit-fast-serum-plasma/): This T4 ELISA kit is designed for the quantitative determination of total Thyroxine in serum and plasma samples (EDTA, lithium heparin, or citrate) to evaluate thyroid dysfunction. Suitable for both in vitro diagnostic and research purposes, this rapid assay (100 minutes) features a 96-well plate format, enabling efficient screening of large experimental series with minimal turnaround time. - [T3 ELISA kit - Serum & Plasma](https://www.immusmol.com/product/t3-elisa-kit-fast-serum-plasma/): This T3 ELISA kit enables the quantitative measurement of triiodothyronine in serum and plasma (EDTA) samples to assess thyroid function. Intended for in vitro diagnostics and research applications, this fast test (70 min) comes in 96-well plate format, allowing the screening of large experimental series within short lead times. - [Androstenedione ELISA kit - Serum & Plasma](https://www.immusmol.com/product/androstenedione-elisa-kit-fast-serum-plasma/): This Androstenedione ELISA kit enables the quantitative measurement of steroid hormone androstenedione in serum and plasma (EDTA) samples. Intended for in vitro diagnotics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. - [Citrulline-to-Arginine ratio ELISA pack](https://www.immusmol.com/product/citrulline-to-arginine-ratio-elisa-pack-serum-plasma/): Measuring the Citrulline-to-Arginine ratio is indicative of nitric oxide synthase (NOS) activity, which converts Arginine into Citrulline and Nitric Oxide (NO). A decreased plasma CIT-to-ARG ratio thus suggests high NO production, and may serve as a biomarker in metabolic and cardiovascular conditions. - [Global Arginine Bioavailability ratio (GABR) ELISA pack](https://www.immusmol.com/product/global-arginine-bioavailability-ratio-gabr-elisa-pack-serum-plasma/): This ELISA pack provides an easy way to assess the plasma/serum Global Arginine Bioavailability Ratio (GABR), defined as arginine/[ornithine + citrulline]. The GABR indicates the availability of arginine for Nitric Oxide production. Low GABR may serve to assess endothelial dysfunction, atherosclerosis, and cardiovascular disorders. - [Citrulline ELISA kit](https://www.immusmol.com/product/citrulline-elisa-kit-highly-sensitive-plasma/): The Citrulline ELISA kit allows easy and accurate quantification of L-citrulline in plasma samples. Plasma citrulline (CIT) can serve as a biomarker to assess intestinal health (enterocyte function) and disorders related to the urea cycle and nitric oxide biosynthesis (see our L-Arginine ELISA kit). With a minimal sample volume of 20 µL and a detection limit of 1.47 μM, the kit enables working with samples of human and animal origin. - [Melatonin ELISA kit](https://www.immusmol.com/product/melatonin-elisa-kit-highly-sensitive-serum-plasma-samples/): The Melatonin ELISA kit enables the accurate quantification of N-acetyl-5-methoxy-tryptamine (Melatonin) in plasma and serum samples. - [N1-Acetyl-Spermidine ELISA kit](https://www.immusmol.com/product/n1-acetyl-spermidine-elisa-kit/): The N1-Acetyl-Spermidine ELISA Kit enables simple, sensitive, and accurate quantification of the polyamine N1-acetylspermidine in biological fluids, including plasma, serum, and cell culture supernatants. Cross-validated against LC-MS in human plasma, the assay delivers reliable results using just 50 µL of sample. Compatible with samples from any species, this kit is suited for both preclinical research and clinical studies. - [N8-Acetyl-Spermidine ELISA kit](https://www.immusmol.com/product/n8-acetyl-spermidine-elisa-kit/): The N8-Acetyl-Spermidine ELISA Kit enables simple, sensitive, and accurate quantification of the polyamine N8-acetylspermidine in biological fluids, including plasma, serum, and cell culture supernatants. Cross-validated against LC-MS in human plasma, the assay delivers reliable results using just 50 µL of sample. Compatible with samples from any species, this kit is suited for both preclinical research and clinical studies. - [Arginine-to-Ornithine ratio ELISA pack](https://www.immusmol.com/product/arginine-ornithine-elisa-pack/): Arginine-to-Ornithine ratio ELISA: Detection in 20 µL serum or plasma (any species). Sensitivity 2.1 µM / 8.5 µM; range 5–200 µM. - [Ornithine ELISA kit](https://www.immusmol.com/product/ornithine-elisa-kit/): The Ornithine ELISA kit allows the easy and highly sensitive measurement of L-Ornithine (Orn) in biological samples from any species. Cross-validated by LC-MS in human plasma samples, the kit was used in recent papers to determine ornithine levels in human & mouse cell culture supernatants. - [L-Histidine ELISA kit](https://www.immusmol.com/product/l-histidine-elisa-kit/): The IS-I-1300R ELISA kit enables the sensitive and quantitative measurement of L-Histidine (His) in plasma samples from any species. Cross-validated against LC-MS in human plasma, the assay offers high sensitivity and requires only 10 µL of sample, making it fit for both preclinical research and clinical studies. - [L-Asparagine ELISA kit](https://www.immusmol.com/product/l-asparagine-elisa-kit/): Accurate and easy-to-implement ELISA kit for L-Asparagine (Asn) quantitation functions, in plasma samples. Min. sample volume: 20μL. Sensitivity: 2.3µM. - [3-Hydroxyanthranilic acid antibody - Rabbit Polyclonal](https://www.immusmol.com/product/3-hydroxyanthranilic-acid-antibody-pab/): This is the first and only anti-3-Hydroxy-Anthranilic acid (3-HAA) rabbit polyclonal antibody available for research use. Confirmed to be highly specific and affine by competitive ELISA, the antibody is currently being validated for IHC and IF use. - [Xanthurenic acid Antibody - Mouse Monoclonal](https://www.immusmol.com/product/xanthurenic-acid-antibody-mab/): IS009 was the first anti-Xanthurenic acid antibody made available to the scientific community, back in 2014. This mouse mAb was validated for IHC and IF in human midbrain tissues, highlighting cytoplasmic presence of xanthurenic acid. - [Histamine release in whole blood - ELISA kit Add-on](https://www.immusmol.com/product/histamine-release-kit-whole-blood-samples/): Intended for research use, this add-on kit to the BA-E-1000R Histamine ELISA kit enables the measurement of histamine release in heparinized whole blood samples, allowing for instance to determine the sensitivity of basophilic granulocytes to specific allergens. - [Glutamate ELISA kit](https://www.immusmol.com/product/glutamate-elisa-kit-any-sample/): This Glutamate ELISA kit enables the quantitative measurement of L-Glutamic acid in a variety of biological samples, including cell cultures, tissue homogenates, urine, plasma, serum, etc. - [Kynurenine to Tryptophan ratio ELISA pack](https://www.immusmol.com/product/kynurenine-tryptophan-ratio-elisa-pack/): The Kynurenine/Tryptophan ratio ELISA pack enables quantitative measurements of tryptophan catabolism along the kynurenine pathway in large numbers of samples. The two kits included in the pack are ready to use. Highly sensitive, with a minimum sample volume of 20µl, they permit the performance of longitudinal studies in mice. - [Octopamine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/octopamine-antibody-rabbit-pab/): The anti-Octopamine antibody IS1033 was validated for immunofluorescence in crayfish brain tissues, using the STAINperfect immunostaining kit A for sample preparation. In combination with the staining kit, this rabbit polyclonal antibody can label Octopamine in cell cultures and tissues for IF/IHC imaging. - [Dopamine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/dopamine-antibody-validated-if/): The anti-dopamine antibody IS1005 was used in recent papers stain mouse primary neurons, human brain tissues, brain organoids, and C. Elegans. - [Histamine ELISA kit - Any sample](https://www.immusmol.com/product/histamine-elisa-kit-any-sample/): This research kit enables the ultra-sensitve measurement of histamine in any biological sample: tissue homogeneates, cell culture supernatants, body fluids, etc. With a minimal sample volume as low as 10µl, this histamine immunoassay allows longitudinal studies in mice and rat models. - [Serotonin ELISA kit - Serum and Urine](https://www.immusmol.com/product/serotonin-elisa-kit-serum-urine-platelets/): This Serotonin (5-HT) ELISA kit is tailored for the rapid measurement of 5-hydroxytryptamine in serum, urine and platelets. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay enables the determination of serotonin levels in up to 40 samples within 75 minutes. - [Glycine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/glycine-antibody-rabbit-pab/): This rabbit polyclonal anti-glycine antibody was validated for immunofluorescence (IF) in mouse primary cortical neurons using the STAINperfect immunostaining kit A. When combined with the kit, this antibody enables direct visualization of glycine in cell cultures, whole mounts, and tissue sections. - [L-Glutamine ELISA kit](https://www.immusmol.com/product/l-glutamine-elisa-kit/): The IS-I-1100 Gln ELISA kit allows for the determination of L-Glutamine in plasma, serum and cell culture supernatants originating from either preclinical or clinical samples, of a volume as low as 10μL and with a sensitivity of 3µM. - [Serotonin Antibody - Goat Polyclonal](https://www.immusmol.com/product/serotonin-antibody-goat-pab/): The rabbit polyclonal anti-serotonin antibody IS1035 was validated using the STAINperfect immunostaining kit A in mouse primary neurons, mouse brain tissues, and crayfish brain tissues, demonstrating robust and specific labeling of serotonin (5-HT). - [Histamine ELISA kit – Any food or beverage](https://www.immusmol.com/product/histamine-elisa-kit-any-food-or-beverage/): This high-sensitive Histamine ELISA kit is tailored for the monitoring of histamine in food and beverage samples, including fish and fish products, sausages, dairy products and wine. Simple and rapid, the test displays high correlation with HPLC. - [GABA Antibody - Chicken Polyclonal](https://www.immusmol.com/product/gaba-antibody-chicken-pab/): Our team validated the chicken polyclonal anti-GABA antibody IS1036 for immunofluorescence (IF) in mouse primary neurons and crayfish tissues using the STAINperfect immunostaining kit A. This antibody supports multiplex staining with rabbit polyclonal or mouse monoclonal antibodies. In recent papers, it allowed specific visualization of gamma-aminobutyric acid (GABA) in human iPSC-derived neurons, mouse primary neurons, and mouse brain tissues. - [Serotonin ELISA kit, Any sample](https://www.immusmol.com/product/serotonin-elisa-kit-any-sample/): Ultra‑sensitive Serotonin ELISA – detect 5 pg / mL from just 1 µL of any sample • Validated across all species • Cited in 25 papers • Ships same day - [Fast Histamine ELISA kit - HistaSure™ - Any fish sample](https://www.immusmol.com/product/histamine-elisa-kit-any-fish-sample/): This fast Histamine ELISA kit was validated and certified by the AOAC Research Institute as an effective method for the quantitative measurement of histamine in fresh, frozen, canned fish samples and fish meals. Performed within 25 minutes, the assay can detect histamine levels between 0,44 ppm and 300ppm in any fish sample, thus complying with regulatory requirements. Product only available for customers outside of France. - [L-Tryptophan Antibody - Mouse Monoclonal](https://www.immusmol.com/product/l-tryptophan-mab/): The anti-tryptophan antibody IS011 was validated in mouse and crayfish brain tissues using the STAINperfect Immunostaining Kit A. Additionally, this monoclonal antibody has been successfully used in recent scientific publications to stain human cells and mouse kidney tissue sections. - [Kynurenic acid Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/kynurenic-acid-antibody-pab/): The anti-kynurenic acid (KYNA) rabbit polyclonal antibody IS1011 was successfully validated for immunohistochemistry (IHC) on human paraffin-embedded brain tissues. Optimal staining was achieved at a 1:2000 dilution, with a single vial sufficient for approximately 400 stainings. - [L-Phenylalanine ELISA kit](https://www.immusmol.com/product/l-phenylalanine-elisa-kit/): Accurate and easy-to-implement ELISA kit for L-Phenylalanine (Phe) quantification in plasma and sera samples. The assay requires a sample volume as low as 20μL and is characterized by a 1.7µM sensitivity - [Quinaldic acid Antibody - Mouse Monoclonal](https://www.immusmol.com/product/quinaldic-acid-antibody-mab/): Our anti-Quinaldic acid antibody is the only primary antibody available to date to stain for quinaldic acid. This mouse monoclonal antibody was validated by our team for immunohistochemistry (IHC) and immufluorescence (IF) in paraffin-embedded tissues from human caudate-putamen region. - [L-Noradrenaline Antibody (Norepinephrine) - Rabbit Polyclonal](https://www.immusmol.com/product/l-noradrenaline-antibody-norepinephrine-rabbit-ab/): The anti-Noradrenaline (NA) antibody IS1042 was validated for immunofluorescence in mouse brain and spinal cord tissues, in combination with the STAINperfect immunostaining kit A. This anti-Norepinephrine antibody was also used to evidence noradrenergic neurons in spider brain (Jin et al, Nature Ecology & Evolution, 2023). - [Epinephrine ELISA kit (Adrenaline) - Plasma & Urine](https://www.immusmol.com/product/epinephrine-elisa-kit-urine-plasma-samples/): This ELISA kit is tailored for the rapid measurement of Adrenaline (Epinephrine) in urine and plasma samples. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay enables to determine Epinephrine levels in up to 40 samples within 4 hours. - [Serotonin Antibody - Mouse Monoclonal](https://www.immusmol.com/product/serotonin-antibody-mouse-mab/): Anti-Serotonin antibody IS040, in combination with the STAINperfect immunostaining kit A, enables reliable detection of 5-HT in whole mounts, cell cultures, and tissue sections. Our team successfully used this antibody to stain embryonic mouse tissues, and recent studies have demonstrated its effectiveness in visualizing serotonin in human midbrain organoids and mouse brain tissues. - [L-Serine ELISA kit](https://www.immusmol.com/product/l-serine-elisa-kit/): L-Serine ELISA kit for the determination of Ser in cell culture supernatant, serum and plasma samples, with a minimal sample volume of 20μL. The kit is easy to implement and well suited for both preclinical and clinical studies. - [Epinephrine ELISA kit (Adrenaline) - Any sample](https://www.immusmol.com/product/epinephrine-elisa-kit-any-sample/): This ELISA kit enables the ultra-sensitive measurement of Adrenaline (Epinephrine) in any biological sample. Intended for research use only, the assay features a lower limit of detection at 3.3 pg/ml and a minimal sample volume as low as 1µl. - [3-HydroxyAnthranilic acid Antibody - Mouse Monoclonal](https://www.immusmol.com/product/3-hydroxyanthranilic-acid-mab/): The first and only anti-3-HydroxyAnthranilic acid mouse antibody available for research use. This primary mouse monoclonal antibody was validated for IHC both in human tumor and brain tissues. When tested by competitive ELISA, the antibody demonstrated strong affinity and high specificity. - [GABA Antibody - Mouse Monoclonal](https://www.immusmol.com/product/gaba-antibody-mouse-mab/): Used with the STAINperfect immunostaining kit A, the anti-GABA antibody IS039 allows to label Gamma-Aminobutyric acid in cell cultures, whole mounts and tissue sections, evidencing GABAergic systems (cell bodies and neuritic network). We successfully performed GABA stainings in rat primary neurons with this antibody, and a recent publication used this anti-GABA antibody in human iPS-derived midbrain organoids. Our range also includes polyclonal anti-GABA antibodies: Rabbit pAb #IS1006, Chicken pAb#IS1036. - [L-Kynurenine ELISA kit](https://www.immusmol.com/product/l-kynurenine-elisa-kit/): Easy-to-use & highly sensitive assay for the quantification of L-Kynurenine across large series of samples. The KYN ELISA features a lower limit of detection at 45.7ng/ml and a minimal sample volume of 20µl, thus allowing longitudinal studies in mice. It is available in RUO and IVD (In vitro diagnostics) formats. - [5-Hydroxyindoleacetic acid (5-HIAA) ELISA kit](https://www.immusmol.com/product/5-hiaa-elisa-kit-urine-samples/): This 5-hydroxyindoleacetic acid ELISA kit is tailored for the rapid measurement of 5-HIAA in urine samples. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay can be performed within 3 hours. - [Quinolinic acid Antibody - Mouse Monoclonal](https://www.immusmol.com/product/quinolinic-acid-mab/): This mouse monoclonal antibody to Quinolinic acid was validated for IF & IHC in human brain tissues. Recent publications relied on this antibody to stain for neurotoxin Quinolinic acid in mouse brain tissues and human atheroma plaques. - [Quinolinic acid Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/quinolinic-acid-antibody-pab/): Validated for immunohistochemical analysis in paraffin-embedded human parkinsonian brain specimens, this anti-Quinolinic acid (QUIN) rabbit polyclonal antibody was recently employed in scientific publications to confirm the presence of Quinolinic acid in FFPE brain and lung tissues using both immunohistochemistry (IHC) and immunohistofluorescence (IHF). - [Norepinephrine ELISA kit - Plasma & Urine](https://www.immusmol.com/product/norepinephrine-elisa-kit-urine-plasma-samples/): This Norepinephrine ELISA kit is tailored for the rapid measurement of Noradrenaline (Norepinephrine) in urine and plasma samples. Intended for in vitro diagnostics, this fast-track quantitative immunoassay enables to determine Norepinephrine levels in up to 40 samples within 4 hours. - [L-Lysine ELISA kit](https://www.immusmol.com/product/l-lysine-elisa-kit/): Validated ELISA kit for Lysine (Lys) quantitation in plasma samples. Accurate and easy-to-implement. Low minimal sample volume: 20μL. 13µM sensitivity. - [Histamine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/histamine-antibody-rabbit-pab/): The anti-histamine antibody IS1039 is a rabbit polyclonal antibody developed to label Histamine in whole mounts, cell culture and tissue sections. The antibody was validated for IF in mouse and crayfish brain tissues, using the STAINperfect immunostaining kit A. - [Picolinic acid Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/picolinic-acid-pab/): This is the first and only anti-Picolinic acid antibody available for research use. Confirmed to be highly specific and affine by competitive ELISA, this rabbit polyclonal antibody is undergoing validation for IHC and IF use. - [Cinnabarinic acid Antibody - Mouse Monoclonal](https://www.immusmol.com/product/cinnabarinic-acid-mab/): The first and only validated anti-Cinnabarinic acid antibody available for research use. IHC validation of this mouse mAb in human brain and breast tumor tissues revealed the presence, in specific cells, of Cinnabarinic acid, a tryptophan metabolite known for its immunomodulatory role. A 2020 paper also used this anti-cinnabarinic antibody to stain mouse brain tissue sections (immunofluorescence). - [Norepinephrine ELISA kit - Any sample](https://www.immusmol.com/product/norepinephrine-elisa-kit-any-sample/): Ultra-Sensitive Norepinephrine ELISA kit (Noradrenaline). Any species, Any Sample (min. vol. 1µl). LoD: 1.3pg/ml. Cited in 30+ papers - [Xanthurenic acid Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/xanthurenic-acid-pab/): IS1014 was the first anti-Xanthurenic acid cited in the literature, by Roussel et al., in 2016. In this paper, this highly affine rabbit pAb was used to label Xanthurenic acid in mouse brain tissue sections and rat primary neurons. - [Metanephrine ELISA kit - Plasma](https://www.immusmol.com/product/metanephrine-elisa-kit-plasma-samples/): This Metanephrine ELISA kit enables the measurement of free L-metanephrine in plasma samples with high sensitivity. Intended for in vitro diagnostics (EU only) & research use, this quantitative immunoassay is based on a simple and fast sample preparation protocol, and offers a limit of detection below 15pg/ml. - [Epinephrine - Norepinephrine ELISA kit - Any sample](https://www.immusmol.com/product/epinephrine-norepinephrine-elisa-kit-any-sample/): This Epinephrine/Norepinephrine ELISA kit enables the ultra-sensitive measurement of Adrenaline (Epinephrine) and Noradrenaline (Norepinephrine) in any biological sample. Intended for research use, the assay features a lower limit of detection at 6.6pg/ml and a minimal sample volume as low as 1µl. - [3-Methoxytyramine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/3-mt-antibody-3-methoxytyramine-rabbit-pab/): The anti-3-Methoxytyramine (3-MT) antibody IS1019 is a rabbit polyclonal antibody validated for IF in mouse brain tissues (whole mounts, free-floating sections). In samples prepared with the STAINperfect immunostaining kit A, this antibody allows direct 3MT visualization in whole mounts, cell cultures and tissue sections. - [Metanephrine ELISA kit - Urine](https://www.immusmol.com/product/metanephrine-elisa-kit-urine-samples/): This Metanephrine ELISA kit enables to quantify metanephrine in urine samples within 2 hours. Intended for in vitro diagnostics (EU only) & research use, this quantitative immunoassay demonstrated good correlation with HPLC. - [Quinolinic Acid ELISA kit](https://www.immusmol.com/product/quinolinic-acid-elisa-kit/): The Quinolinic Acid ELISA kit is optimized for the quantitation of Quinolinic Acid within serum and plasma samples. Working with a low sample volume of 25µL, this assay enables pre-clinical and clinical sample testing. - [Kynurenic Acid ELISA kit](https://www.immusmol.com/product/kynurenic-acid-elisa-kit/): The Kynurenic Acid ELISA kit is optimized for the quantitation of Kynurenic Acid (KYNA) within serum samples. Working with a 50µL sample volume, this assay enables pre-clinical and clinical sample testing. - [Epinephrine - Norepinephrine ELISA kit - Plasma & Urine](https://www.immusmol.com/product/epinephrine-norepinephrine-elisa-kit-plasma-urine/): This fast-track ELISA kit is tailored for the rapid measurement of Adrenaline (Epinephrine) and Noradrenaline (Norepinephrine) in urine and plasma samples. This quantitative immunoassay enables to determine Epinephrine & Norepinephrine levels in up to 40 samples in duplicate within 4 hours. - [Normetanephrine ELISA kit - Plasma](https://www.immusmol.com/product/normetanephrine-elisa-kit-plasma-samples/): This Normetanephrine ELISA kit enables the fast measurement of free L-Normetanephrine in plasma samples. Intended for in vitro diagnostics (EU only) & research use, this quantitative immunoassay is based on a simple and fast sample preparation protocol, and offers a limit of detection below 18pg/ml. - [Normetanephrine ELISA kit - Urine](https://www.immusmol.com/product/normetanephrine-elisa-kit-urine-samples/): This Normetanephrine ELISA kit enables to quantify normetanephrine in urine samples within 2 hours. Intended for in vitro diagnostics (EU only) & research use, this quantitative immunoassay demonstrated good correlation with HPLC. - [3 Catecholamines ELISA kit - Plasma & Urine](https://www.immusmol.com/product/3-catecholamines-elisa-kit-plasma-urine-samples/): This 3 catecholamines ELISA kit is tailored for the rapid measurement of Adrenaline (Epinephrine), Noradrenaline (Norepinephrine) and Dopamine in urine and plasma samples. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay can be performed in samples from any species within 5 hours. - [Free Metanephrine - Normetanephrine ELISA kit - Plasma](https://www.immusmol.com/product/free-metanephrine-normetanephrine-elisa-kit-plasma-samples/): This Free Metanephrines ELISA kit enables the fast measurement of free L-metanephrine and free L-Normetanephrine in plasma samples. Intended for research use and in vitro diagnostics (EU only), this quantitative immunoassay is based on a simple and fast sample preparation step, and features a limit of detection below 25pg/ml. - [L-DOPA Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-dopa-antibody-rabbit-pab/): The anti-L-DOPA antibody IS1030 was validated for immunofluorescence in crayfish tissues and mouse primary neurons using the STAINperfect immunostaining kit A, demonstrating specific and accurate labeling of L-DOPA. - [3 Catecholamines ELISA kit - Any sample](https://www.immusmol.com/product/3-catecholamines-elisa-kit-any-sample/): This Catecholamine ELISA kit enables the ultra-sensitive measurement of Epinephrine, Norepinephrine and Dopamine in any biological sample. Intended for research use only, the assay features a lower limit of detection at 6.6pg/ml and a minimal sample volume as low as 1µl. - [Metanephrine-Normetanephrine ELISA kit - Urine](https://www.immusmol.com/product/metanephrine-normetanephrine-elisa-kit-urine-samples/): This Metanephrines ELISA kit enables to quantify metanephrine and normetanephrine in urine samples within 2 hours. Intended for in vitro diagnostics & Research, this quantitative immunoassay demonstrated good correlation with HPLC. - [Kynurenine/Kynurenic Acid/Quinolinic Acid ELISA pack (3-KYNs ELISA pack)](https://www.immusmol.com/product/kynurenine-kynurenic-acid-quinolinic-acid-elisa-pack-3-kyns-elisa-pack/): The Kynurenine/Kynurenic Acid/Quinolinic acid ELISA pack enables quantitative measurements of tryptophan catabolism along the kynurenine pathway in large numbers of samples. Highly sensitive, with a minimum sample volume of 25-50µL, they enable pre-clinical and clinical sample testing. - [Normetanephrine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/normetanephrine-antibody-rabbit-pab/): The rabbit polyclonal anti-normetanephrine antibody IS1028 was validated for immunohistofluorescence (IF) in crayfish tissues and mouse brain whole mounts using the STAINperfect immunostaining kit A. In combination with this kit, IS1028 can also enable effective visualization of normetanephrine in cell cultures and tissue sections. - [Kynurenic Acid/Quinolinic Acid ELISA pack](https://www.immusmol.com/product/kynureninic-acid-quinolinic-acid-elisa-pack/): The two kits included in the pack are optimized for the quantitation of Kynurenic Acid (KYNA) and Quinolinic Acid (QA) within serum and plasma samples. Working with a 25-50µL sample volume, these assays enable pre-clinical and clinical sample testing. - [L-Tyrosine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-tyrosine-antibody-rabbit-pab/): The anti-L-Tyrosine antibody IS1037 was validated for immunofluorescence (IF) in mouse midbrain tissues in combination with the STAINperfect immunostaining kit A. Combined with this staining kit, this rabbit polyclonal antibody allows direct L-Tyrosine visualization in cell cultures, whole mounts, tissue sections. - [L-Phenylalanine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-phenylalanine-antibody-rabbit-pab/): Our team validated the rabbit polyclonal anti-L-phenylalanine antibody IS1038 for immunofluorescence (IF) in mouse midbrain tissues using the STAINperfect immunostaining kit A, demonstrating specific and accurate labeling of L-phenylalanine. - [L-Homoarginine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-homoarginine-antibody-pab/): This rabbit polyclonal antibody recognizes L-Homoarginine at a 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors such as Asymetric DiMethyl Arginine (ADMA), Symetric DiMethyl Arginine (SDMA) and L-Arginine. Used with the STAINperfect immunostaining kit A, this antibody could allow direct L-Homoarginine visualization in cell culture and tissue samples (IF or IHC). - [L-Arginine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-arginine-antibody-pab/): Validated by direct and competitive ELISA, this rabbit polyclonal antibody recognizes L-Arginine at 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors such as L-Ornithine, L-Glutamate and L-Homoarginine. Our team is currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. - [GABA Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/gaba-antibody-rabbit-pab/): The anti-GABA antibody IS1006 has been validated by our team for immunofluorescence in primary mouse and rat neurons using the STAINperfect immunostaining kit A. Additionally, recent scientific studies have employed this antibody to highlight GABAergic systems in human stem cell-derived neurons and rabbit olfactory bulb tissues. When combined with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody enables the clear visualization of gamma-aminobutyric acid (GABA) in cell cultures, tissue sections, and whole mounts from any species. - [L-Ornithine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-ornithine-antibody-pab/): This anti-L-Ornithine antibody recognizes its target at a 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors such as L-Glutamine, L-Glutamate and L-Arginine. Our team is currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. - [Serotonin Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/serotonin-antibody-rabbit-pab/): The anti-Serotonin antibody IS1007 allows for accturate labeling of 5-HT in cell cultures, tissue sections, and whole mounts prepared with the STAINperfect immunostaining kit A. Our team has validated this anti-5-HT antibody for immunofluorescence applications in crayfish tissues (whole mounts) as well as in mouse primary neurons and brain tissues (both tissue sections and whole mounts). - [L-Glutamate Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-glutamate-antibody-rabbit-polyclonal/): The anti-L-Glutamate antibody IS1001 has been validated for immunofluorescence applications in rodent primary neurons, mouse brain tissues, and crayfish brain tissues, in combination with the STAINperfect immunostaining kit A. Recent publications have leveraged this antibody to effectively stain glutamatergic systems in both mouse tissues and primary neurons. - [L-Glutamine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-glutamine-antibody-pab/): This rabbit polyclonal antibody recognizes L-Glutamine at a 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors. Using the STAINperfect immunostaining kit A, this primary antibody was used to visualize Glutamine in midbrain organoids (IF) and human tumor tissues (IHC). - [L-Glutamate Antibody - Mouse Monoclonal](https://www.immusmol.com/product/l-glutamate-antibody-mouse-mab/): Anti-L-Glutamate antibody IS018 is a mouse monoclonal Ab used for IF in mouse primary neurons & human iPSC-derived neurons (2019 paper). Combined with the STAINperfect immunostaining kit A, this antibody accurately labels L-GLutamic acid in whole mounts, cell culture and tissue sections. - [L-Asparagine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-asparagine-antibody-pab/): Validated by direct and competitive ELISA, this rabbit polyclonal antibody recognizes L-Asparagine at 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors such as L-Glutamine and L-Aspartate. Combined with the STAINperfect immunostaining kit A, this antibody allows direct L-Asparagine imaging in various types of samples (cell cultures, tissue sections, whole mounts). - [D-Glutamate Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/d-glutamate-antibody/): IS1002 is the only anti-D-Glutamate antibody available to date. This primary rabbit polyclonal antibody allows to stain for D-glutamic acid in cell cultures, whole mounts and tissue section when used in combination with the STAINperfect immunostaining kit A. Our team validated this antibody in mouse primary cortical neurons. - [D-Serine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/d-serine-antibody/): The anti-D-Serine antibody IS1004 is the first and only antibody validated for immunofluorescence (IF) applications to date. When paired with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody enables clear visualization of D-Serine in cell cultures, tissue sections, and whole mounts. Our team successfully used IS1004 to detect D-Serine in mouse brain tissue sections. - [L-Serine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-serine-antibody/): The anti-L-Serine antibody IS1003 is the first and only antibody available specifically for L-Serine detection. When paired with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody enables clear visualization of L-Serine in cell cultures, tissue sections, and whole mounts. Our team successfully employed IS1003 to detect L-Serine in mouse primary neurons and brainstem tissues. - [L-Tryptophan ELISA kit](https://www.immusmol.com/product/l-tryptophan-elisa-kit/): This ELISA kit enables the quantitative measurement of L-Tryptophan in biological fluids and cell culture supernatants. Intended for in vitro diagnotics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. - [HomoArginine ELISA kit](https://www.immusmol.com/product/homoarginine-elisa-kit/): HomoArginine (hArg) ELISA kit for the determination of hArg in serum and plasma samples working with a minimal sample volume of 20μL. Easy to implement and well-suited for both preclinical and clinical studies. - [Dopamine ELISA kit - Plasma & Urine](https://www.immusmol.com/product/dopamine-elisa-kit-urine-plasma-samples/): Dopamine ELISA kit for the rapid measurement of Dopamine (DA) in urine and plasma. samples. 40 samples within 4 hours. Cited in 7 papers - [STAINperfect™ immunostaining kit A](https://www.immusmol.com/product/stainperfect-immunostaining-kit-a/): Achieve high-quality stainings with 30+ antibodies to neurotransmitters, amino-acids, & their metabolites. Cited in 20+ papers. Validated in rodent & human specimens. - [Dopamine ELISA kit - Any sample](https://www.immusmol.com/product/dopamine-elisa-kit-any-sample/): This research Dopamine ELISA kit enables the ultra-sensitive measurement of Dopamine (DA) in any biological sample. 1 µl min. sample volume. - [Arginine ELISA kit](https://www.immusmol.com/product/arginine-elisa-kit/): The Arginine (Arg) ELISA kit for the determination of Arg in serum, plasma, and supernatants, working with a sample volume of 20μL. Easy to implement and well-suited for both preclinical and clinical studies. - [GABA ELISA kit - Any sample](https://www.immusmol.com/product/gaba-elisa-kit-any-sample/): This GABA ELISA kit enables the measurement of Gamma-aminobutyric acid in any biological sample. Intended for in vitro diagnostics, this quantitative assay can be performed in cell cultures, tissue homogenates, urine, plasma, serum, etc. - [L-Kynurenine Antibody - Mouse Monoclonal](https://www.immusmol.com/product/l-kynurenine-mab/): Our anti-L-Kynurenine antibody IS1003 enabled to illustrate, for the first time, the presence of L-kynurenine in human brain and tumor samples by IHC and IF. In the literature, the antibody was used to stain for kynurenine in mouse tissues (tumor, brain, heart) and human samples (cell culture, atheroma plaque, and tumor specimens). This mouse monoclonal antibody can be used in combination with other primary antibodies to kynurenine metabolites (rabbit polyclonals available). - [L-Kynurenine Antibody - Rabbit Polyclonal](https://www.immusmol.com/product/l-kynurenine-pab/): The rabbit polyclonal anti-L-kynurenine antibody IS1012 was validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) human tumor tissues at a 1:500 dilution. Recently, this antibody was successfully used in two studies to stain macaque immune cells and human FFPE lung tissues for L-kynurenine. - [Kynurenic acid Antibody - Mouse Monoclonal](https://www.immusmol.com/product/kynurenic-acid-mab/): The monoclonal IS010 anti-Kynurenic acid (KYNA) antibody was validated for IHC and IF in human caudate putamen tissues. Cited in literature. Highly affine and specific mAb. - [Anthranilic acid Antibody - Mouse Monoclonal](https://www.immusmol.com/product/anthranilic-acid-antibody-mab/): The monoclonal anti-Anthranilic acid antibody 10G1-F1 was validated for immunohistochemistry (IHC) in human brain tissues. Highly specific, as demonstrated by competitive ELISA, the antibody consistently delivered clean and reproducible stainings. - [Histamine ELISA kit - Plasma & Urine](https://www.immusmol.com/product/histamine-elisa-kit-urine-plasma-samples/): In vitro diagnostics & research enzyme immunoassay (ELISA) for the quantitative determination of histamine levels in urine and plasma samples. The immunoassay can be combined with the add-on kit BA-E-1100, to quantify histamine release in whole blood. --- ## Landing Pages - [Validated L-Tryptophan antibodies](https://www.immusmol.com/landing/l-tryptophan-antibodies/): Use our L-Tryptophan antibodies to stain cell cultures, tissue sections, whole mounts. Validated for IF & IHC and cited in peer-reviewed articles. - [Serine antibodies](https://www.immusmol.com/landing/serine-antibodies-imaging/): In combination with the STAINperfect immuno-staining kit, our anti-serine antibodies enable the visualization of L-Serine & D-Serine in biological samples (cell cultures, tissue sections, and whole mounts). L- and D-Serine ELISA kits are also available for rapid measurement of Serine in biological samples. - [L-Kynurenine antibodies](https://www.immusmol.com/landing/l-kynurenine-antibodies-for-ihc-if-imaging/): Our anti-L-Kynurenine antibodies enable the direct labelling of kynurenine in cell cultures, tissue sections, and whole mounts. Validated for IF & IHC and cited in peer-reviewed articles, our kynurenine antibodies (rabbit pAb and mouse mAb) were used in mouse samples (bone marrow, heart) and human specimens (FFPE tumors, brain tissues). - [Kynurenic acid antibodies](https://www.immusmol.com/landing/kynurenic-acid-antibodies-for-ihc-if-imaging/): Our anti-Kynurenic acid antibodies enable the direct labelling of kynurenic acid (KYNA) in cell cultures, tissue sections, and whole mounts. Validated for IF & IHC in paraffin-embedded human brain tissues, our kynurenine antibodies are available as rabbit pAB and mouse mAb for easy multiplex imaging. - [Xanthurenic acid antibodies](https://www.immusmol.com/landing/xanthurenic-acid-antibodies-for-ihc-if-imaging/): Our anti-Xanthurenic acid antibodies enable the direct labelling of Xanthurenic acid in cell cultures, tissue sections, and whole mounts. Validated for IF & IHC in paraffin-embedded human brain tissues, our Xanthurenic acid antibodies are available as rabbit pAB and mouse mAb, allowing co-staining with other primary antibodies. - [3-HydroxyAnthranilic acid (3-HAA) antibodies](https://www.immusmol.com/landing/3-hydroxyanthranilic-acid-antibodies-for-ihc-if-imaging/): Our anti-3-HydroxyAnthranilic acid antibodies enable the direct labelling of 3-HAA in cell cultures, tissue sections, and whole mounts. Validated for IHC in paraffin-embedded human brain and colon tissues, our 3-HydroxyAnthranilic acid antibodies are available as rabbit pAB and mouse mAb, allowing co-staining with other primary antibodies. - [Quinolinic acid antibodies](https://www.immusmol.com/landing/quinolinic-acid-antibodies-for-if-ihc-imaging/): Our anti-Quinolinic acid antibodies enable the visualization of Quinolinate (QUIN) in cell cultures, tissue sections, and whole mounts. Validated for IF & IHC in paraffin-embedded human brain tissues, our Quinolinic acid antibodies were used in 4 papers to evidence the toxin in various pathological contexts: Covid-19, glioblastoma, and atherogenesis. - [STAINperfect immunostaining kits](https://www.immusmol.com/landing/stainperfect-immunostaining-kits/): Visualize neurotransmitters, amino acids, and metabolites in cells, tissues, & whole mounts. Compatible with 30+ primary antibodies. - [5-HT antibodies](https://www.immusmol.com/landing/5-ht-antibodies-immunostaining-kit-serotonin-imaging/): In combination with the STAINperfect immuno-staining kit, our anti-5-HT antibodies enables the visualization of serotonin biological samples (cell cultures, tissues sections and whole mount). We also offer a range of highly sensitive ELISA kits for easy and rapid quantification of 5-HT in any type of sample. - [GABA antibodies](https://www.immusmol.com/landing/gaba-antibodies-immunostaining-kit-gaba-imaging/): Combined with the STAINperfect immuno-staining kit, our anti-GABA antibodies enables the direct imaging of γ-aminobutyric acid in preclinical and clinical samples (cells, tissues sections, whole mounts, …). A GABA ELISA kit is also available for rapid measurements. - [Glutamate antibodies](https://www.immusmol.com/landing/glutamate-antibodies-immunostaining-kit/): In combination with the STAINperfect immuno-staining kit, our anti-glutamate antibodies enable the visualization of L-Glutamate & D-Glutamate in biological samples (cell cultures, tissue sections, and whole mounts). A L-Glutamate ELISA kit is also available for rapid measurements of L-Glutamic acid in biological samples. - [Norepinephrine ELISA kits](https://www.immusmol.com/landing/norepinephrine-elisa-kits-fast-easy-noradrenaline-quantification/): Our Norepinephrine ELISA kits enable fast & easy measurement of Norepinephrine (Noradrenaline) in both preclinical samples (cell culture and organoid supernatant, in vivo samples including microdialysates,...) as well as in body fluids (urine, plasma) in the context of clinical studies. - [Histamine ELISA kits](https://www.immusmol.com/landing/histamine-elisa-kits-high-sensitivity-for-biological-samples-fast-assays-for-food-beverage/): Highly sensitive Histamine ELISA kits for prelinical samples and body fluids (minimal volume = 10µl), and Fast Histamine Tests for Fish, Food and Beverage. - [Dopamine ELISA kits](https://www.immusmol.com/landing/dopamine-elisa-kits-for-fast-easy-dopamine-quantification/): Our range of Dopamine ELISA kits enables easy and accurate quantification of dopamine release in low volume samples such as cell culture and organoid supernatant, microdialysates, and reproducible measurements in clinical samples such as human plasma & urine. - [Epinephrine ELISA kits](https://www.immusmol.com/landing/epinephrine-elisa-kits-for-fast-easy-adrenaline-quantification/): Our range of Epinephrine ELISA kits enables easy and accurate quantification of Epinephrine (Adrenaline), together with other catecholamines such as Norepinephrine, Dopamine, and Metanephrines, in preclinical samples such as cell culture and organoid supernatant, microdialysates, as well as reproducible measurements in clinical samples such as human plasma & urine. - [Serotonin ELISA kits](https://www.immusmol.com/landing/serotonin-elisa-kits-fast-accurate-5-ht-quantification/): We have two Serotonin ELISA kits : an ultra-sensitive kit for 5-HT quantification in any type of prelinical sample (minimal volume = 1µl) and a fast ELISA kit to measure serotonin levels in urine, serum and platelets within 75 minutes. - [5-HT antibodies & immunostaining kit](https://www.immusmol.com/landing/5-ht-antibodies-immunostaining-kit/) --- # # Detailed Content ## Pages - Published: 2025-07-28 - Modified: 2025-07-28 - URL: https://www.immusmol.com/worry-free-warranty/ Last updated: 28/07/2025IMMUSMOL offers warranties on purchased products (worry-free warranty):30-Day Free Return & RefundCustomer may return any product within thirty (30) days of receipt for a full refund, provided that the product is unused, in its original packaging, and in resalable condition. Free Replacement for Shipping DamageIf a product is damaged during shipping, customer must notify IMMUSMOL within five (5) days of receipt, providing evidence of the damage. IMMUSMOL will promptly replace the damaged product at no additional cost. Product Replacement or Refund for Quality IssuesIf a product does not meet quality standards, Customer shall notify IMMUSMOL within thirty (30) days of receipt, providing a detailed description of the defect and any supporting documentation, such as original lab data. Following evaluation by IMMUSMOL's customer support team, IMMUSMOL will, at its discretion, replace the product or issue a full refund. Limitation of LiabilityIMMUSMOL's liability for any claim relating to the products shall be limited to the replacement of the product or the issuance of a refund as outlined above. Claims will only be accepted upon receipt of all necessary details and supporting documentation. . Contact detailsFor any notice or claim, please use the following contact details:Immusmol SAS229 Cours de l'Argonne33000 Bordeaux,France+33 (0)5 6431 1170Contact --- > Our Metanephrines ELISA kits enable fast & easy measurement of Metanephrine (metadrenaline) and Normetanephrine (Normetadrenaline) in plasma and urine samples. Other catecholamines, such as Epinephrine, Norepinephrine, and Dopamine, can be quantified with the same product range. - Published: 2025-06-25 - Modified: 2025-06-26 - URL: https://www.immusmol.com/shop/metanephrines-elisa-kits/ Metanephrines ELISA kits – Quantification of Metanephrine & Normetanephrine in Urine & Plasma samples Target Metanephrine Normetanephrine Samples Plasma Urine About catecholamine ELISAs Sale ! Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Free Metanephrine – Normetanephrine ELISA kit – Plasma Fast, Plasma, IVD (EU only) or Research use €949 €1098 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Metanephrine ELISA kit – Plasma High Sensitive, Fast, Plasma, IVD (EU only) or Research use €549 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Metanephrine ELISA kit – Urine Fast ( --- > We have developed a unique range of ELISA kits to assess Tryptophan metabolism along the Kynurenine pathway. Highly sensitive, featuring low minimal sample volumes, and easy-to-use, our Kynurenines ELISA kits constitute an alternative to LC/MS for the quantification of L-Tryptophan, L-Kynurenine, Kynurenic acid, and Quinolinic acid in biological fluids: cell culture supernatants, serum, plasma, and urine. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/kynurenine-pathway-elisa-kits-easy-fast-quantification-tryptophan-metabolites/ Kynurenine pathway ELISA kits: Easy & Fast quantification of Tryptophan metabolites 100+ citations in the literature Target 5-HIAA Kynurenic Acid Kynurenine Melatonin Quinolinic Acid Serotonin Tryptophan Features Fast High Sensitivity Samples Flexible Plasma Saliva Serum Serum/Plasma Urine Our antibodies against Tryptophan metabolites Select options This product has multiple variants. The options may be chosen on the product page ELISA kits 5-Hydroxyindoleacetic acid (5-HIAA) ELISA kit Fast (3h), Urine (≥50µl), IVD (EU only) and RUO €399 Add to cart / quote ELISA kits Kynurenic Acid ELISA kit High Sensitivity. Serum. Min. vol. 50µL. Cited in 7 papers. €599 -12% Add to cart / quote ELISA kits Kynurenic Acid/Quinolinic Acid ELISA pack High Sensitivity. Plasma, Serum. Min. Vol. 25-50µL. Cited in literature €1049€1198 Sale ! Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Kynurenine to Tryptophan ratio ELISA pack High Sensitive, ≥ 20µL Biological fluids, Cited in 50+ papers €1049 €1198 -17% Add to cart / quote ELISA kits Kynurenine/Kynurenic Acid/Quinolinic Acid ELISA pack (3-KYNs ELISA pack) High Sensitivity. Plasma, Serum. Min. Vol. 25-50µL. Cited in literature €1499€1797 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits L-Kynurenine ELISA kit High Sensitivity, biological fluids (≥ 20µL), cited in 68 papers €599 Select options This product has multiple variants. The options may be chosen on the product page Amino acids L-Tryptophan ELISA kit High sensitivity, biological fluids (≥ 20µL), cited in 50+ papers €599... --- > Our range of ELISA kits for arginine and its metabolites enables rapid and easy measurements in cell culture supernatant, serum, and plasma samples. The quantitative assays require low minimal sample volumes (20 to 50 μL). An ELISA pack is available to measure the Arginine/Ornithine ratio, as well as ELISA kits to quantify polyamines. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/arginine-metabolism-elisa-kits-sensitive-fast-easy-to-use-research-assays/ Arginine metabolism ELISA kits Target Arginine Citrulline Homoarginine N1-Acetyl-Spermidine N8-Acetyl-Spermidine Ornithine Features Fast High Sensitivity Samples Flexible Plasma Saliva Serum Serum/Plasma Urine Arginine metabolism antibodies Add to cart / quote Amino acids Arginine ELISA kit High Sensitivity, Plasma, Serum, Supernatant (≥ 20µL), Cited in 3 papers €599 -12% Add to cart / quote Arginine metabolism Arginine-to-Ornithine ratio ELISA pack High Sensitivity, Plasma & Serum (≥ 20µL) €1049€1198 Add to cart / quote Amino acids Citrulline ELISA kit High Sensitivity, Plasma (≥ 20µL) €599 -12% Add to cart / quote Amino acids Citrulline-to-Arginine ratio ELISA pack High Sensitivity, Plasma & Serum (≥ 20µL) €1049€1198 -17% Add to cart / quote Arginine metabolism Global Arginine Bioavailability ratio (GABR) ELISA pack High Sensitivity, Plasma & Serum (≥ 20µL) €1499€1797 Add to cart / quote Amino acids HomoArginine ELISA kit High Sensitivity, Plasma & Serum (≥ 20µL), Cited in literature €599 Add to cart / quote Arginine metabolism N1-Acetyl-Spermidine ELISA kit High Sensitivity, Serum, Plasma, Cell Culture Supernatant (≥ 50µL) €599 Add to cart / quote Arginine metabolism N8-Acetyl-Spermidine ELISA kit High Sensitivity, Serum, Plasma, Cell Culture Supernatant (≥ 20µL) €599 Add to cart / quote Arginine metabolism Ornithine ELISA kit High Sensitivity, Plasma (≥ 20µL), Cited in literature €599 --- > Our ELISA kits enable the quantification of Thyroid hormones, Androgens, Progestogens, Estrogens, Corticoids, and Neuroendocrine tumor markers in plasma, urine and saliva. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/elisa-kits-for-the-measurement-of-hormones/ ELISA kits for the measurement of hormones 75+ citations in the literature Target Androgens Catecholamines Corticoids Estrogens Metanephrines Progestogens Thyroid hormones Tumor markers Samples Flexible Plasma Saliva Serum Serum/Plasma Urine Select options This product has multiple variants. The options may be chosen on the product page ELISA kits 17-OH-Progesterone ELISA kit – Human Serum and Plasma Fast (90 min), Serum & Plasma, IVD (EU only) or RUO €299 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits 17-OH-Progesterone ELISA kit – Saliva Fast (75 min), Saliva, IVD (EU only) or RUO €289 Select options This product has multiple variants. The options may be chosen on the product page Corticoids 25-OH Vitamin D ELISA kit I Fast I Serum and Plasma Fast (1h45 min), Serum & Plasma, IVD (EU only) or RUO €349 -28% Add to cart / quote Catecholamines 3 Catecholamines ELISA kit – Any sample Ultra-Sensitive, Any sample ≥ 1 µl, Research use only €1299€1797 Sale ! Select options This product has multiple variants. The options may be chosen on the product page Catecholamines 3 Catecholamines ELISA kit – Plasma & Urine Fast (5h), Dopamine / Epinephrine / Norepinephrine in Urine & Plasma, Cited in 5 papers €1099 €1497 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits 5-Hydroxyindoleacetic acid (5-HIAA) ELISA kit Fast (3h), Urine (≥50µl), IVD (EU only) and RUO €399 Select options This product has multiple variants. The... --- > Our catecholamine ELISA kits permit easy and accurate measurements of Epinephrine (Adrenaline), Norepinephrine (Noradrenaline), and Dopamine levels in preclinical samples such as 2D cell culture and 3D organoid supernatants, microdialysates, as well as fast testing of clinical samples such as plasma, serum, and urine. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/catecholamines-elisa-kits-fast-easy-quantification-of-adrenaline-noradrenaline-and-dopamine/ ELISA kits for the measurement of catecholamines 60+ citations in the literature Target Dopamine Epinephrine Norepinephrine Features Fast High Sensitivity Samples Flexible Plasma Saliva Serum Serum/Plasma Urine About antibodies against catecholamines -28% Add to cart / quote Catecholamines 3 Catecholamines ELISA kit – Any sample Ultra-Sensitive, Any sample ≥ 1 µl, Research use only €1299€1797 Sale ! Select options This product has multiple variants. The options may be chosen on the product page Catecholamines 3 Catecholamines ELISA kit – Plasma & Urine Fast (5h), Dopamine / Epinephrine / Norepinephrine in Urine & Plasma, Cited in 5 papers €1099 €1497 Add to cart / quote Catecholamines Dopamine ELISA kit – Any sample Ultra-sensitive, ≥ 1µl sample, Cited in 30+ papers €599 Select options This product has multiple variants. The options may be chosen on the product page Catecholamines Dopamine ELISA kit – Plasma & Urine Fast (4h), Research or In Vitro Diagnostics applications €499 -17% Add to cart / quote Catecholamines Epinephrine – Norepinephrine ELISA kit – Any sample Ultra-Sensitive, Any sample ≥ 1 µl, Research use only €999€1198 Sale ! Select options This product has multiple variants. The options may be chosen on the product page Catecholamines Epinephrine – Norepinephrine ELISA kit – Plasma & Urine Fast (4h), 300µl plasma or 10µl urine, Cited in literature €699 €998 Add to cart / quote Catecholamines Epinephrine ELISA kit (Adrenaline) – Any sample Ultra-Sensitive, Any sample ≥ 1 µl, Research use only €599 Select options This product has multiple variants. The options... --- > Immusmol provides a comprehensive range of robust and reliable ELISA kits for the precise quantification of thyroid hormones. Our assays facilitate accurate diagnosis of thyroid disorders, including hypothyroidism, hyperthyroidism, thyroiditis, Graves’ disease, and Hashimoto’s thyroiditis. Additionally, our kits support investigations into thyroid hormone metabolism abnormalities such as non-thyroidal illness syndrome (euthyroid sick syndrome) and elevated reverse T3 levels. They are also ideally suited for assessing thyroid function across diverse research fields, including cardiovascular, neurological, reproductive, and developmental biology. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/elisa-kits-for-the-measurement-of-thyroid-function-markers-in-serum-and-plasma/ ELISA kits for the Measurement of Thyroid Function Markers Target FT3 FT4 Reverse T3 T3 T4 TSH Samples Flexible Plasma Saliva Serum Serum/Plasma Urine Select options This product has multiple variants. The options may be chosen on the product page ELISA kits FT3 ELISA kit – Serum Fast (75 min), Serum, IVD (EU only) or RUO €249 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits FT4 ELISA kit – Serum Fast (75 min), Serum, IVD (EU only) or RUO €249 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Reverse T3 (rT3) ELISA kit – Serum & Plasma Fast (105 min), Serum & Plasma, IVD (EU only) or RUO €249 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits T3 ELISA kit – Serum & Plasma Fast (70 min), Serum & Plasma, IVD (EU only) or RUO €249 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits T4 ELISA kit – Serum & Plasma Fast (100 min), Serum & Plasma, IVD (EU only) or RUO €249 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits TSH ELISA kit – Serum & Plasma Fast (2h), Serum & Plasma, IVD (EU only) or RUO €249 --- > Immusmol offers a comprehensive portfolio of ELISA kits for accurate measurement of essential androgens and steroid hormones. Our assays facilitate the diagnosis of endocrine disorders, such as polycystic ovary syndrome (PCOS), adrenal hyperplasia, adrenal tumors, and androgen-secreting tumors. They are also valuable tools for assessing male reproductive health—including hypogonadism and infertility—as well as evaluating androgen excess in females. Additionally, our immunoassays support the monitoring of hormone replacement therapies, including androgen supplementation and anti-androgen treatments in prostate cancer, and enable the detection of steroid use in sports medicine and anti-doping research. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/elisa-kits-for-the-measurement-of-androgen-and-steroid-hormone-markers-in-serum-plasma-and-saliva/ ELISA kits for the Measurement of Androgens and Steroid Hormone Markers Target 3α-Diol-G Androstenedione DHEA DHEA-S DHT Testosterone Samples Plasma Saliva Serum Serum/Plasma Urine Select options This product has multiple variants. The options may be chosen on the product page Androgens Androstanediol-Glucuronide ELISA kit – Human Serum Fast (45 min), Serum, IVD (EU only) or RUO €279 Select options This product has multiple variants. The options may be chosen on the product page Androgens Androstenedione ELISA kit – Human Saliva Fast (75 min), Saliva, IVD (EU only) or RUO €309 Select options This product has multiple variants. The options may be chosen on the product page Androgens Androstenedione ELISA kit – Serum & Plasma Fast (90 min), Serum & Plasma, IVD (EU only) or RUO €269 Select options This product has multiple variants. The options may be chosen on the product page Androgens DHEA ELISA kit – Human Saliva Fast (90 min), Saliva, IVD (EU only) or RUO €289 Select options This product has multiple variants. The options may be chosen on the product page Androgens DHEA ELISA kit – Human Serum and Plasma Fast (90 min), Serum & Plasma, IVD (EU only) or RUO €279 Select options This product has multiple variants. The options may be chosen on the product page Androgens DHEA-S ELISA kit – Human Saliva Fast (30 min), Saliva, IVD (EU only) or RUO €289 Select options This product has multiple variants. The options may be chosen on the product page Androgens DHEA-S ELISA kit –... --- > Explore ELISA kits for fast and accurate measurement of progestogens like Progesterone,17-OH-Progesterone, and Pregnenolone in saliva, serum & plasma. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/elisa-kits-for-the-measurement-of-progestogens/ ELISA kits for the Measurement of Progestogens Target 17-OH-Progesterone Pregnenolone Progesterone Samples Flexible Plasma Saliva Serum Serum/Plasma Urine Select options This product has multiple variants. The options may be chosen on the product page ELISA kits 17-OH-Progesterone ELISA kit – Human Serum and Plasma Fast (90 min), Serum & Plasma, IVD (EU only) or RUO €299 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits 17-OH-Progesterone ELISA kit – Saliva Fast (75 min), Saliva, IVD (EU only) or RUO €289 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Pregnenolone ELISA kit – Serum Samples Fast (75 min), Serum, IVD (EU only) or RUO €279 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Progesterone ELISA kit – Saliva Fast (75 min), Saliva, IVD (EU only) or RUO €309 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Progesterone ELISA kit – Serum and Plasma Fast (75 min), Serum & Plasma, IVD (EU only) or RUO €269 --- > Immusmol provides an extensive portfolio of ELISA kits designed for precise quantification of adrenal hormones and stress biomarkers. Our assays support accurate diagnosis of adrenal disorders, including Addison’s disease, Cushing’s syndrome, adrenal insufficiency, adrenal adenoma and carcinoma, as well as Conn’s syndrome (primary hyperaldosteronism). Additionally, these immunoassays facilitate research in stress biology and circadian rhythm, encompassing psychobiology, psychosocial stress, cortisol regulation, and chronic stress studies. They also offer valuable insights for endocrinology and metabolic disorder research. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/corticoid-elisa-kits-for-the-measurement-of-adrenal-hormones-stress-biomarkers-in-serum-plasma-urine-and-saliva/ Corticoid ELISA kits for the Measurement of Adrenal Hormones & Stress Biomarkers Target 25-OH Vitamin D Aldosterone Corticosterone Cortisol Samples Flexible Plasma Saliva Serum Serum/Plasma Urine Select options This product has multiple variants. The options may be chosen on the product page Corticoids 25-OH Vitamin D ELISA kit I Fast I Serum and Plasma Fast (1h45 min), Serum & Plasma, IVD (EU only) or RUO €349 Select options This product has multiple variants. The options may be chosen on the product page Corticoids Aldosterone ELISA kit – Human Serum, Plasma, Urine Fast (2h), Human Serum, Plasma, Urine, IVD or RUO €299 Select options This product has multiple variants. The options may be chosen on the product page Corticoids Corticosterone ELISA kit – Serum and Plasma Fast (75 min), Serum & Plasma, IVD (EU only) or RUO €329 Select options This product has multiple variants. The options may be chosen on the product page Corticoids Cortisol ELISA kit – Human Saliva Fast (90 min), Saliva, IVD (EU only) or RUO €279 Select options This product has multiple variants. The options may be chosen on the product page Corticoids Cortisol ELISA kit – Human urine Fast (75 min), Urine, IVD (EU only) or RUO €299 Select options This product has multiple variants. The options may be chosen on the product page Corticoids Cortisol ELISA kit – Serum and Plasma Fast (75 min), Serum & Plasma, IVD (EU only) or RUO €269 --- > Immusmol provides rigorously validated ELISA kits for precise quantification of female sex steroid hormones, including estrogens. Our immunoassays facilitate the accurate diagnosis of female reproductive disorders such as polycystic ovary syndrome (PCOS), ovarian insufficiency, menopause-related conditions, amenorrhea, and infertility. These kits are also valuable for monitoring high-risk pregnancies and detecting hormone-dependent malignancies, including breast, ovarian, and endometrial cancers. Furthermore, our assays effectively support the monitoring of hormone replacement therapies and fertility treatments. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/elisa-kits-for-the-measurement-of-estrogens-female-sex-steroids-in-serum-plasma-and-saliva/ ELISA kits for the Measurement of Estrogens Target Estradiol Estriol Estrone Samples Plasma Saliva Serum Serum/Plasma Urine Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Estradiol ELISA kit – Serum and Plasma Fast (2h), Serum & Plasma, IVD (EU only) or RUO €269 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Estradiol ELISA kit I Human Saliva Fast (3h), Saliva, IVD (EU only) or RUO €289 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Estrone ELISA kit – Serum and Plasma Fast (75 min), Serum & Plasma, IVD (EU only) or RUO €279 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Estrone ELISA kit I Fast I Saliva Fast (75 min), Saliva, IVD (EU only) or RUO €399 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Free Estriol ELISA kit – Serum Fast (90 min), Serum, IVD (EU only) or RUO €279 – €319 --- > Fast & robust ELISA kits for the measurement of neuroendocrine tumors: Chromogranin A, 5-HIAA, Metanephrines, ... in urine and plasma samples - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/elisa-kits-for-the-measurement-of-neuroendocrine-tumor-markers/ ELISA kits for the Measurement of Neuroendocrine Tumor Markers Target 5-HIAA Chromogranin A Metanephrine Normetanephrine Samples Flexible Plasma Saliva Serum Serum/Plasma Urine Select options This product has multiple variants. The options may be chosen on the product page ELISA kits 5-Hydroxyindoleacetic acid (5-HIAA) ELISA kit Fast (3h), Urine (≥50µl), IVD (EU only) and RUO €399 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Chromogranin A ELISA (CgA) – Serum Samples Fast (2h30), Serum & Plasma, IVD (EU only) or RUO €549 Sale ! Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Free Metanephrine – Normetanephrine ELISA kit – Plasma Fast, Plasma, IVD (EU only) or Research use €949 €1098 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Metanephrine ELISA kit – Plasma High Sensitive, Fast, Plasma, IVD (EU only) or Research use €549 Select options This product has multiple variants. The options may be chosen on the product page ELISA kits Metanephrine ELISA kit – Urine Fast ( --- > We developed and validated a full range of antibodies for neurotransmitter imaging. Combined with the STAINperfect immuno-staining kit, our antibodies enable the visualization of neuromediators by immunofluorescence (IF) or ImmunoHistoChemistry (IHC) in cell cultures, tissue sections, and whole mounts. A range of research ELISA kits for easy quantification of neurotransmitters is also available. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/validated-antibodies-for-neurotransmitter-imaging-if-or-ihc-staining/ Validated antibodies for neurotransmitter imaging (IF or IHC staining) 20+ citations in the literature Target D-Glutamate D-serine Dopamine GABA Glycine Histamine L-Glutamate L-Serine Norepinephrine Octopamine Serotonin Host species Chicken Goat Mouse Rabbit Staining procedure STAINperfect kit Standard staining Neurotransmitter ELISA kits Add to cart / quote Amino acids D-Glutamate Antibody – Rabbit Polyclonal Only anti-D-glutamate antibody, Validated for IF in mouse primary neurons. €449 Add to cart / quote Amino acids D-Serine Antibody – Rabbit Polyclonal First and only D-Serine antibody validated for IF (brain tissues) €449 Read more Antibodies Dopamine Antibody – Rabbit Polyclonal Used for IF in primary & iPS-derived neurons, organoids & brain tissues. Cited in 10+... €449 Add to cart / quote Antibodies GABA Antibody – Chicken Polyclonal Validated for IF in primary & iPS-derived neurons, and brain tissues. Cited in literature €449 Add to cart / quote Antibodies GABA Antibody – Mouse Monoclonal Validated IF in primary neurons & brain organoids. Cited in literature €449 Add to cart / quote Antibodies GABA Antibody – Rabbit Polyclonal Used for IF in primary & iPSC-derived neurons, and brain tissues. Cited in literature €449 Add to cart / quote Amino acids Glycine Antibody – Rabbit Polyclonal Validated for IF in primary neurons. Cited in literature €449 Add to cart / quote Antibodies Histamine Antibody – Rabbit Polyclonal Validated for IF in mouse & crayfish brain tissues €449 Add to cart / quote Amino acids L-Glutamate Antibody – Mouse Monoclonal Validated for IF in primary neurons & iPSC-derived neurons.... --- > We developed and validated a range of antibodies for the visualization of amino acids and their metabolites in biological samples, with a focus on arginine and tryptophan metabolism. Combined with the STAINperfect immuno-staining kit, our primary antibodies allow for high-quality IF and IHC imaging. A range of research ELISA kits for the quantification of amino acids is also available. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/validated-antibodies-amino-acid-imaging/ Validated antibodies for amino acid imaging Target Arginine Asparagine Citrulline D-Glutamate D-serine Glutamine Glycine Histidine Homoarginine L-Glutamate L-Serine Lysine Ornithine Phenylalanine Tryptophan Tyrosine Host species Chicken Goat Mouse Rabbit Staining procedure STAINperfect kit Standard staining ELISA kits for Amino Acids Add to cart / quote Amino acids D-Glutamate Antibody – Rabbit Polyclonal Only anti-D-glutamate antibody, Validated for IF in mouse primary neurons. €449 Add to cart / quote Amino acids D-Serine Antibody – Rabbit Polyclonal First and only D-Serine antibody validated for IF (brain tissues) €449 Add to cart / quote Amino acids Glycine Antibody – Rabbit Polyclonal Validated for IF in primary neurons. Cited in literature €449 Add to cart / quote Amino acids L-Arginine Antibody – Rabbit Polyclonal High Specificity & Affinity. IF / IHC / ICC €449 Add to cart / quote Amino acids L-Asparagine Antibody – Rabbit Polyclonal High affinity & specificity, IF / IHC / ICC €449 Add to cart / quote Amino acids L-Citrulline Antibody – Rabbit Polyclonal High specificity & affinity, IF / IHC / ICC €449 Add to cart / quote Amino acids L-Glutamate Antibody – Mouse Monoclonal Validated for IF in primary neurons & iPSC-derived neurons. Cited in literature €449 Add to cart / quote Amino acids L-Glutamate Antibody – Rabbit Polyclonal Validated for IF in primary neurons & brain tissues. Cited in literature €449 Add to cart / quote Amino acids L-Glutamine Antibody – Rabbit Polyclonal Validated for IF & IHC in human organoids and tumor specimens, cited in 2... --- > ImmuSmol developed a unique range of antibodies to visualize amino acid L-Arginine and its key metabolites, such as L-Ornithine and L-Citrulline, as well as polyamines like N1-Acetyl-Spermidine and N8-Acetyl-Spermidine, and related amino acids such as L-Lysine and Homoarginine. A range of research ELISA kits for easy measurements of Arginine metabolism is also available. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/antibodies-to-assess-arginine-metabolism/ Primary antibodies to assess arginine metabolism Target Arginine Citrulline Homoarginine N1-Acetyl-Spermidine N8-Acetyl-Spermidine Ornithine Arginine metabolism ELISA kits Add to cart / quote Amino acids L-Arginine Antibody – Rabbit Polyclonal High Specificity & Affinity. IF / IHC / ICC €449 Add to cart / quote Amino acids L-Citrulline Antibody – Rabbit Polyclonal High specificity & affinity, IF / IHC / ICC €449 Add to cart / quote Amino acids L-Homoarginine Antibody – Rabbit Polyclonal High Specificity & Affinity I IF / IHC / ICC €449 Add to cart / quote Amino acids L-Ornithine Antibody – Rabbit Polyclonal High specificity & affinity, IF / IHC / ICC €449 Add to cart / quote Antibodies N1-Acetyl-Spermidine Antibody – Rabbit Polyclonal High specificity & affinity, IF / IHC / ICC €449 Add to cart / quote Antibodies N8-Acetyl-Spermidine Antibody – Rabbit Polyclonal High specificity & affinity, IF / IHC / ICC €449 -37% Add to cart / quote Amino acids STAINperfect™ – Trial pack Try the STAINperfect kit with 2 antibodies among 30 (neurotransmitters, amino acids, metabolites... ). €389€620 Sale ! Read more Amino acids STAINperfect™ – Trial pack (Copy) Try the STAINperfect kit with 2 antibodies among 30 (neurotransmitters, amino acids, metabolites... ). €620 Original price was: €620. €387Current price is: €387. -12% Add to cart / quote Amino acids STAINperfect™ immunostaining kit A Compatible with 30+ antibodies. Cell culture/Whole mounts/Tissue sections. Cited in 18 papers €299€340 --- > ImmuSmol developed and validated a unique range of antibodies to visualize L-Tryptophan metabolites along the kynurenine pathway. Available as mouse monoclonals or rabbit polyclonals, our antibodies to kynurenines were tested for IF and IHC, mainly in mouse and human tissues. A range of research ELISA kits for easy measurements of tryptophan metabolism is also available. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/validated-antibodies-to-tryptophan-metabolites-kynurenines/ Validated Antibodies to Tryptophan Metabolites (Kynurenines) 20+ citations in the literature Target 3-Hydroxyanthranilic acid Anthranilic acid Cinnabarinic acid Kynurenic Acid Kynurenine Picolinic acid Quinolinic Acid Serotonin Tryptophan Xanthurenic acid Host species Chicken Goat Mouse Rabbit Staining procedure STAINperfect kit Standard staining Tryptophan metabolism ELISA kits Add to cart / quote Antibodies 3-HydroxyAnthranilic acid Antibody – Mouse Monoclonal Used for IHC in FFPE brain, lung, tumor tissues. Only 3-HAA mAb available. Cited in... €449 Add to cart / quote Antibodies 3-Hydroxyanthranilic acid antibody – Rabbit Polyclonal Only rabbit pAb available to 3-HAA €449 Add to cart / quote Antibodies Anthranilic acid Antibody – Mouse Monoclonal Validated for IHC in FFPE brain tissues €449 Add to cart / quote Antibodies Cinnabarinic acid Antibody – Mouse Monoclonal Used for IF & IHC in brain & cancer tissues I Cited in literature €449 Add to cart / quote Antibodies Kynurenic acid Antibody – Mouse Monoclonal Used for IHC/IF in FFPE brain tissues. Cited in literature €449 Add to cart / quote Antibodies Kynurenic acid Antibody – Rabbit Polyclonal Validated for IHC in FFPE human brain tissues €449 Add to cart / quote Antibodies L-Kynurenine Antibody – Mouse Monoclonal Used for IF & IHC in brain, heart, and tumor tissues I Cited in 10+... €449 Add to cart / quote Antibodies L-Kynurenine Antibody – Rabbit Polyclonal Used for IHC in FFPE lung & tumor tissues. Cited in literature €449 Add to cart / quote Amino acids L-Tryptophan Antibody – Mouse Monoclonal Used for IF in... --- > We developed and validated a range of antibodies to evidence dopamine, its precursors, and downstream metabolites in cell cultures and tissue samples (IF or IHC). Combined with the STAINperfect immuno-staining kit, our primary antibodies accurately reach their targets. A range of research ELISA kits for catecholamine quantification is also available. - Published: 2025-06-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/antibodies-to-dopamine-its-metabolites-catecholamines/ Antibodies for catecholamine imaging (including dopamine & its metabolites) 15+ citations in the literature Target 3-Methoxytyramine Dopamine L-DOPA Norepinephrine Phenylalanine Tyrosine Host species Chicken Goat Mouse Rabbit Staining procedure STAINperfect kit Standard staining Catecholamine ELISA kits Add to cart / quote Antibodies 3-Methoxytyramine Antibody – Rabbit Polyclonal Validated for IF in brain tissues €449 Read more Antibodies Dopamine Antibody – Rabbit Polyclonal Used for IF in primary & iPS-derived neurons, organoids & brain tissues. Cited in 10+... €449 Add to cart / quote Antibodies L-DOPA Antibody – Rabbit Polyclonal Validated for IF in primary neurons & tissues €449 Add to cart / quote Antibodies L-Noradrenaline Antibody (Norepinephrine) – Rabbit Polyclonal Validated for IF brain & spinal cord tissues I Cited in literature €449 Add to cart / quote Amino acids L-Phenylalanine Antibody – Rabbit Polyclonal Validated for IF in mouse brain tissues €449 Add to cart / quote Amino acids L-Tyrosine Antibody – Rabbit Polyclonal Validated for IF in mouse midbrain tissues €449 Add to cart / quote Antibodies Normetanephrine Antibody – Rabbit Polyclonal Valided for IF in ganglia & midbrain tissues €449 -37% Add to cart / quote Amino acids STAINperfect™ – Trial pack Try the STAINperfect kit with 2 antibodies among 30 (neurotransmitters, amino acids, metabolites... ). €389€620 Sale ! Read more Amino acids STAINperfect™ – Trial pack (Copy) Try the STAINperfect kit with 2 antibodies among 30 (neurotransmitters, amino acids, metabolites... ). €620 Original price was: €620. €387Current price is: €387. -12% Add to cart / quote... --- > Our range of highly sensitive research ELISA kits enables fast & easy quantification of amino acids in cell supernatant, plasma, serum, and urine samples. Additional ELISA kits for the analysis of downstream metabolic pathways are also available, including glutamine metabolites, polyamines, catecholamines, and kynurenines. - Published: 2025-06-16 - Modified: 2025-06-23 - URL: https://www.immusmol.com/shop/elisa-kits-quantification-amino-acids/ ELISA kits for the quantification of amino acids 60+ citations in the literature Target Arginine Asparagine D-serine Glutamine Histamine Histidine Homoarginine L-Glutamate L-Serine Lysine Phenylalanine Tryptophan Features Fast High Sensitivity Samples Flexible Plasma Saliva Serum Serum/Plasma Urine About amino acid antibodies Add to cart / quote Amino acids Arginine ELISA kit High Sensitivity, Plasma, Serum, Supernatant (≥ 20µL), Cited in 3 papers €599 Add to cart / quote Amino acids Citrulline ELISA kit High Sensitivity, Plasma (≥ 20µL) €599 -12% Add to cart / quote Amino acids Citrulline-to-Arginine ratio ELISA pack High Sensitivity, Plasma & Serum (≥ 20µL) €1049€1198 Add to cart / quote Amino acids D-Serine ELISA kit High Sensitivity, Serum, plasma, CSF, supernatant (≥ 50µL) €599 Select options This product has multiple variants. The options may be chosen on the product page Amino acids Glutamate ELISA kit Any sample, IVD (EU only) or RUO, Cited in 5 papers €599 Add to cart / quote Amino acids HomoArginine ELISA kit High Sensitivity, Plasma & Serum (≥ 20µL), Cited in literature €599 Add to cart / quote Amino acids L-Asparagine ELISA kit High Sensitivity, Plasma (≥ 20µL) €599 Add to cart / quote Amino acids L-Glutamine ELISA kit High Sensitivity, Plasma, Serum, Supernatant (≥ 10µL) €599 Add to cart / quote Amino acids L-Histidine ELISA kit High Sensitivity, Plasma (≥ 10µL) €599 Add to cart / quote Amino acids L-Lysine ELISA kit High Sensitivity, Plasma (≥ 20µL) €599 Add to cart / quote Amino acids L-Phenylalanine ELISA kit High Sensitivity,... --- - Published: 2025-03-21 - Modified: 2025-06-30 - URL: https://www.immusmol.com/contact-us/ Contact us Write to our team Please enable JavaScript in your browser to complete this form. Please enable JavaScript in your browser to complete this form. Tell us what you need: *--- Select Choice ---Request a quoteUpload purchase orderEnquire about a productEnquire about our custom servicesOtherName *FirstLastEmail *Phone (for delivery) * Organization *Your Institution/CompanyBilling Address *Address Line 1Address Line 2CityState / Province / RegionPostal Code--- Select country ---AfghanistanAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia (Plurinational State of)Bonaire, Saint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCabo VerdeCambodiaCameroonCanadaCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo (Democratic Republic of the)Cook IslandsCosta RicaCroatiaCubaCuraçaoCyprusCzech RepublicCôte d'IvoireDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEswatini (Kingdom of)EthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuamGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and McDonald IslandsHondurasHong KongHungaryIcelandIndiaIndonesiaIran (Islamic Republic of)IraqIreland (Republic of)Isle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea (Democratic People's Republic of)Korea (Republic of)KosovoKuwaitKyrgyzstanLao People's Democratic RepublicLatviaLebanonLesothoLiberiaLibyaLiechtensteinLithuaniaLuxembourgMacaoMadagascarMalawiMalaysiaMaldivesMaliMaltaMarshall IslandsMartiniqueMauritaniaMauritiusMayotteMexicoMicronesia (Federated States of)Moldova (Republic of)MonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorth Macedonia (Republic of)Northern Mariana IslandsNorwayOmanPakistanPalauPalestine (State of)PanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalPuerto RicoQatarRomaniaRussian FederationRwandaRéunionSaint BarthélemySaint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwedenSwitzerlandSyrian Arab RepublicTaiwan, Republic of ChinaTajikistanTanzania (United Republic of)ThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkmenistanTurks and Caicos IslandsTuvaluTürkiyeUgandaUkraineUnited Arab EmiratesUnited Kingdom of Great Britain and Northern IrelandUnited States Minor Outlying IslandsUnited States of AmericaUruguayUzbekistanVanuatuVatican City StateVenezuela (Bolivarian Republic of)VietnamVirgin Islands (British)Virgin Islands (U. S. )Wallis and FutunaWestern SaharaYemenZambiaZimbabweÅland IslandsCountryShippingShipping is different than billingShipping AddressAddress Line 1Address Line 2CityState... --- - Published: 2025-02-12 - Modified: 2025-02-12 - URL: https://www.immusmol.com/cart/ You may be interested in... Your cart is currently empty! New in store --- > Our range of ELISA kits for neurotransmitter analysis provide a fast, easy-to-use and accurate alternative to HPLC/Mass-Spec approaches for the measurement of neuromediators. Our ultra-sensitive kits are designed to fit any prelinical sample, with a very low minimal sample volume, thus allowing the quantification of neurotransmitter release in cell culture and organoid supernatant, as well as rodent microdyalisates. In addition, we offer a range of fast ELISA kits design for rapid measurements in urine and plasma samples. - Published: 2025-02-12 - Modified: 2025-06-26 - URL: https://www.immusmol.com/shop/elisa-kits-for-neurotransmitter-quantification/ ELISA kits for neurotransmitter quantification 90+ citations in the literature Target D-Serine Dopamine Epinephrine GABA Histamine L-Glutamate L-Serine Norepinephrine Serotonin Features Fast High Sensitivity Samples Flexible Plasma Saliva Serum Serum/Plasma Urine About neurotransmitter imaging -28% Add to cart / quote Catecholamines 3 Catecholamines ELISA kit – Any sample Ultra-Sensitive, Any sample ≥ 1 µl, Research use only €1299€1797 Sale ! Select options This product has multiple variants. The options may be chosen on the product page Catecholamines 3 Catecholamines ELISA kit – Plasma & Urine Fast (5h), Dopamine / Epinephrine / Norepinephrine in Urine & Plasma, Cited in 5 papers €1099 €1497 Add to cart / quote Amino acids D-Serine ELISA kit High Sensitivity, Serum, plasma, CSF, supernatant (≥ 50µL) €599 Add to cart / quote Catecholamines Dopamine ELISA kit – Any sample Ultra-sensitive, ≥ 1µl sample, Cited in 30+ papers €599 Select options This product has multiple variants. The options may be chosen on the product page Catecholamines Dopamine ELISA kit – Plasma & Urine Fast (4h), Research or In Vitro Diagnostics applications €499 -17% Add to cart / quote Catecholamines Epinephrine – Norepinephrine ELISA kit – Any sample Ultra-Sensitive, Any sample ≥ 1 µl, Research use only €999€1198 Sale ! Select options This product has multiple variants. The options may be chosen on the product page Catecholamines Epinephrine – Norepinephrine ELISA kit – Plasma & Urine Fast (4h), 300µl plasma or 10µl urine, Cited in literature €699 €998 Add to cart / quote Catecholamines Epinephrine ELISA kit (Adrenaline)... --- - Published: 2024-10-10 - Modified: 2024-10-10 - URL: https://www.immusmol.com/login-email/ Enter your email address to join or login --- - Published: 2024-10-10 - Modified: 2024-10-10 - URL: https://www.immusmol.com/password/ What's your password ? --- - Published: 2024-10-10 - Modified: 2024-10-10 - URL: https://www.immusmol.com/signup-page/ Welcome! --- - Published: 2024-10-10 - Modified: 2024-10-10 - URL: https://www.immusmol.com/password-reset/ Check your email and enter your new password. Minimum 8 characters Uppercase letters, lowercase letters, and at least one number Cancel Save password --- - Published: 2022-04-13 - Modified: 2025-07-28 - URL: https://www.immusmol.com/immusmol-terms-conditions/ Welcome to Immusmol’s website and thank you for your interest in our company. To use www. immusmol. com and purchase Immusmol products and services, you must agree to our terms & conditions, together with our online privacy & security policy: Terms & Conditions of Use Terms & Conditions of Sale Worry-free warranty Terms & Conditions of Services Online privacy and security policy Please feel free to contact us for any question. --- - Published: 2022-04-13 - Modified: 2025-06-25 - URL: https://www.immusmol.com/immusmol-terms-conditions-of-use/ Last updated : September 18, 2018 Article 1. Website operator The present terms and conditions of use (“terms” or “conditions”) govern the way the website www. immusmol. com (« website » or « site ») is accessed and used. The website is operated by Immusmol SAS (“Immusmol”, “we”, “our” or “us”), a limited liability company with share capital of 50,000 euros, registered in the Bordeaux Register of Companies under number B 753 232 719. Immusmol is located at 229 Cours de l'Argonne, 33000 Bordeaux, France. Immusmol is represented by Alban Bessede, Chief Executive Officer. The website www. immusmol. com is an informational and merchant website, which has been declared to the CNIL, the French data protection agency, under no. 1746074. Article 2. Scope and acceptance of terms and conditions of use By accessing, browsing or downloading any part of the website, the user (“user”, “users”, “you”, “your”), either logged in or not, agrees to the present terms and conditions of use together with Immusmol's online security and privacy policy. IF YOU DO NOT AGREE TO THE PRESENT TERMS & CONDITIONS, IMMEDIATELY STOP ACCESSING IMMUSMOL. COM. We reserve the right to amend the present terms and conditions at any time and for any reason. Changes to the present terms and conditions will apply immediately. We therefore advise you to read our terms and conditions of use on a regular basis. Additional terms may apply for users contracting distribution, license, sale or service agreements. See our terms & conditions section. We reserve... --- - Published: 2022-04-13 - Modified: 2025-06-25 - URL: https://www.immusmol.com/terms-conditions-of-sale/ Last updated: April 14 ,2018Article 1 – Definition, scope, and acceptance of terms & conditionsThe present terms and conditions of sale (“terms” or “conditions”) govern the way Immusmol SAS (“Immusmol”, “we”, “our” or “us”) sells research products to commercial entities (“client”, “you” or “your”) through the website www. immusmol. com (« website » or « site »). Immusmol SAS is a limited liability company with a share capital of 50,000 euros, registered in the Bordeaux Register of Companies under number B 753 232 719. Immusmol is a business-to-business company. We exclusively serve private companies, liberal professions, public institutions, and more generally any person acting in a professional capacity. Our terms & conditions are available on each and every page of the website. Express acceptance of our terms and conditions of sales is systematically required on the order confirmation page, before proceeding to payment. Therefore, placing a purchase order through our website shall be deemed to constitute unconditional acceptance of the present terms and conditions. We reserve the right to amend the present terms and conditions at any time and for any reason. Changes to the present terms and conditions will apply immediately, except for purchase orders already transmitted. We therefore advise you to read our terms & conditions before placing any order on our website. Unless otherwise expressly agreed to in writing, the present Terms & Conditions shall supersede all prior communications and agreements between parties. When completed with the purchase order, they constitute a Contract of sale between Immusmol... --- - Published: 2022-04-13 - Modified: 2025-06-26 - URL: https://www.immusmol.com/immusmol-terms-conditions-of-service/ Last updated: May 19th, 2018Article 1. Definition, scop,e and acceptance of terms & conditionsThe present terms and conditions (“terms” or “conditions”) govern the way Immusmol SAS (“ImmuSmol”, “we”, “our” or “us”) provides contract research services (“services”) to commercial entities (“client”, “you” or “your”). Immusmol SAS is a limited liability company with a share capital of 50,000 euros, registered in the Bordeaux Register of Companies under number B 753 232 719. Immusmol is a business-to-business company. We exclusively serve private companies, liberal professions, public institutions, and more generally, any person acting in a professional capacity. Our terms of service are available on each and every page of our website and are systematically provided with our service proposals. Written agreement of the service proposal by the client shall therefore be deemed to constitute acceptance of the present terms and conditions. We reserve the right to amend the present terms and conditions at any time and for any reason. Changes to the present terms and conditions will apply immediately, except for contract services already accepted. We therefore advise you to read the present terms and conditions before signing any service proposal. Unless otherwise expressly agreed to in writing, the present terms & conditions shall supersede all prior communications and agreements between parties. When completed with the signed service proposal, they constitute a contract (“service agreement”) between Immusmol and the Client. Changes to the present terms and conditions shall only be considered binding if confirmed by Immusmol in writing in the business proposal. Article... --- - Published: 2022-03-27 - Modified: 2025-06-24 - URL: https://www.immusmol.com/immusmol-distributors/ const clusterStyles = } ]; /* Fonction pour créer un logo circulaire en haute résolution */ function circularLogo(url, size = 40) { return new Promise(resolve => { const img = new Image; img. crossOrigin = 'anonymous'; img. onload = => { const dpr = window. devicePixelRatio || 1; const canvas = document. createElement('canvas'); canvas. width = canvas. height = size * dpr; const ctx = canvas. getContext('2d'); ctx. imageSmoothingEnabled = true; ctx. imageSmoothingQuality = 'high'; ctx. beginPath; ctx. arc(canvas. width / 2, canvas. height / 2, canvas. width / 2, 0, Math. PI * 2); ctx. closePath; ctx. clip; ctx. drawImage(img, 0, 0, canvas. width, canvas. height); resolve(canvas. toDataURL); }; img. src = url; }); } let allMarkers = ; let allEntries = ; let markerCluster; function initImmusmolMap { const map = new google. maps. Map(document. getElementById('immusmol-map'), { zoom: 2, center: { lat: 20, lng: 0 }, }); const listContainer = document. getElementById('immusmol-list'); const searchInput = document. getElementById('country-search'); const geocoder = new google. maps. Geocoder; fetch('https://www. immusmol. com/wp-json/wp/v2/immusmol_store? per_page=100') . then(res => res. json) . then(data => { const geoPromises = data. map((store, index) => new Promise(resolve => { const fields = store. meta || {}; if (! fields. address) return resolve; geocoder. geocode({ address: fields. address }, (results, status) => { if (status ! == 'OK') return resolve; const position = results. geometry. location; circularLogo(fields. logo). then(dataURL => { const marker = new google. maps. Marker({ position, icon: { url: dataURL, scaledSize: new google. maps. Size(40, 40), anchor: new... --- > We’re a human-size company, which brings together biochemists, cell biologists, immunologists, medical oncologists and data scientists under the same roof (learn about our CRO activity). - Published: 2022-03-14 - Modified: 2025-06-26 - URL: https://www.immusmol.com/careers-at-immusmol/ What you'll find at Immusmol 25+ colleaguesWe're a human-size company, which brings together biochemists, cell biologists, immunologists, medical oncologists and data scientists under the same roof (learn about our CRO activity). A lab in the Bergonié Cancer CenterImmusmol operates a 600m² in Bordeaux, at the Institut Bergonié - the Comprehensive Cancer Center of the Nouvelle Aquitaine Region. A house in the city centerIn 2024, we moved our offices to a freshly renovated house next to the Institut Bergonié. It’s a place for work, meetings, lunchtime, and social events. Young parents welcomeWe arrange day-nursery for babies. And we are flexible in terms of working schedules, to make the life of young parents at little bit less challenging. Apply now! Please enable JavaScript in your browser to complete this form. Please enable JavaScript in your browser to complete this form. First name *Last name *Email *Your phone * Single Line Text *Your motivations *Your resume (pdf, 10 Mo max size) * Click or drag a file to this area to upload. Submit --- > Immusmol develops mouse monoclonal antibodies (mAbs) for small molecule detection (amino acid metabolites, lipids, saccharids, toxins, steroids, etc.) by IHC or ELISA. Highly reliable, small molecule mAbs are particularly suited to diagnostic & theranostic applications. - Published: 2022-02-01 - Modified: 2025-06-20 - URL: https://www.immusmol.com/custom-small-molecule-antibody-services-anti-hapten-antibodies/custom-mouse-monoclonal-antibodies-against-small-molecules/ Immusmol develops mouse monoclonal antibodies (mAbs) for small molecule detection (amino acid metabolites, lipids, saccharids, toxins, steroids, etc. ) by IHC or ELISA. Highly reliable, small molecule mAbs are particularly suited to diagnostic & theranostic applications. Advantages of small molecule monoclonal antibodies High specificity & affinity – Internal selection protocols are implemented to ensure our mAbs translate into robust and accurate immunoassays. Cross-species reactivity – Unlike proteins, small molecules are conserved throughout phylogenesis. A single small molecule mAb can thus be applied to virtually any biological sample. High reproducibility & availability – Produced in vitro by a single immortalized cell clone, our monoclonal antibodies meet industrial standards for quality and scalability. Our approach for the development of small molecule mAbs A personalized strategy for antigen design, based on an in-depth analysis of the physico-chemical properties, immunogenicity and potential competitors of the small molecule target to address, tailored to your intended use of the antibody. Quality controls, deliverables, Go/No-Go decision points at the end of each phase, to ensure transparent projects with limited risk and deferred costs. Full ownership of the antibody-producing clone is granted to the client at the end of the study, together with at least 2mg of purified monoclonal immunoglobulin. Meeting your project requirements To meet your specific needs, we can complement our standard mAb production process with additional services, such as:Custom molecule synthesisAntigen coupling validation by NMRMeasurement of antibody binding affinity by surface plasmon resonance (Biacore)Complementary antibody production and purificationAntibody validation for IHC, IF, ICC, ELISA, ...... --- > Immusmol develops rabbit polyclonal antibodies (pAbs) against any molecule under 900 Daltons: steroids, nucleotides, small molecule drugs, chemical pollutants, pesticide residues, etc. Compatible with ELISA and IHC technologies, our pAbs represent inexpensive and easy-to-implement tools, allowing accurate and robust detection of small molecules in cells, tissues, and biological fluids. - Published: 2022-02-01 - Modified: 2025-06-20 - URL: https://www.immusmol.com/custom-small-molecule-antibody-services-anti-hapten-antibodies/custom-rabbit-polyclonal-antibodies-against-small-molecules/ Immusmol develops rabbit polyclonal antibodies (pAbs) against any molecule under 900 Daltons: steroids, nucleotides, small molecule drugs, chemical pollutants, pesticide residues, etc. Compatible with ELISA and IHC technologies, our pAbs represent inexpensive and easy-to-implement tools, allowing accurate and robust detection of small molecules in cells, tissues, and biological fluids. Advantages of small molecule polyclonal antibodies High affinity: rabbits generate highly affine polyclonal antibodies, thus maximizing the overall sensitivity of immunoassays. Cross-species reactivity: small molecules are conserved throughout species. Polyclonal antibodies raised against small molecules are thus applicable to biological samples of any origin. Low cost & rapid production: directly purified from rabbit serum, polyclonal antibodies represent a cost- and time-efficient alternative to monoclonal antibodies for research and diagnostic applications. Small molecule pAbs: Immusmol’s added-value A core expertise in antigen design: combining over 25 years of experience in the design of small molecule/protein carrier conjugates, our team develops cross-linking strategies to optimize immune response and subsequent antibody quality. A standard 12-week production process: 2 rabbits, 4 immunizations, 2 bleeds. Quality-controlled deliverables: each bleed is characterized by ELISA for titer, affinity and specificity. Based on ELISA results, the client determines the bleeds to be purified. We deliver 10 to 30 ml of purified lyophilized serum, other crude antisera and preimmune serum (control). Meeting your project requirements Our standard polyclonal antibody production process can be customized to meet your specific needs. Complementary services include:Additional rabbits for larger quantitiesAntibody purification by antigen-specific affinity or protein A/G affinityAntibody validation for IHC, ICC, IF, ELISA, ...... --- - Published: 2022-01-19 - Modified: 2025-06-26 - URL: https://www.immusmol.com/credits/ Graphics : Immusmol Web design and development : Kipdev. io --- > Based on our expertise in antigen design, we design custom small molecule antibodies against a large variety of targets, such as Amino acid metabolites, Lipids, Saccharids, Steroids, Nucleotides, Small molecule drugs, Toxins, Drug residues, Pesticides residues, Chemical pollutants - Published: 2022-01-18 - Modified: 2025-06-20 - URL: https://www.immusmol.com/custom-small-molecule-antibody-services-anti-hapten-antibodies/ Based on our expertise in antigen design, we develop custom small molecule antibodies against a large variety of targets, such as: Amino acid metabolites Lipids Saccharids Steroids Nucleotides Toxins Small molecule drugs Drug residues Pesticides residues Chemical pollutants (carcinogens, neurotoxins, endocrine disruptors) Different clonalities & hosts to fit your application Mouse monoclonal antibodies High reproducibility & availability – Produced in vitro by a single immortalized cell clone, our monoclonal antibodies meet industrial standards for quality and scalability. More about mAbs Rabbit polyclonal antibodies High-affinity, reduced cost & rapid production: directly purified from rabbit serum, polyclonal antibodies represent a cost- and time-efficient alternative to mAbs. More about pAbs Applications of small molecule antibodies Research, diagnostics, theranostics, food safety, or even environmental monitoring... Small molecule antibodies can be used in a wide range of applications. More precisely, they allow: Small molecule visualization by immunohistochemistry (IHC) or immunofluorescence (IF) using standard procedure or the STAINperfect kit. Small molecule quantification using ELISA/EIA assays, an easy, cost- and time-efficient alternative to LC-MS and aptamer-based technologies. Our added value A one-to-one approach: starting from your desired application, we assess and discuss with you the addressability, immunogenicity and potential competitors of your target. Production of polyclonal or monoclonal small molecule antibodies: we fully master each process from antigen design up to antibody validation and purification. Expertise in immunoassay applications: immunohistochemistry, immunofluorescence, ELISA, etc. Contact us Please enable JavaScript in your browser to complete this form. Please enable JavaScript in your browser to complete this form. Your name... --- > Immusmol develops antibodies and immunoassays (ELISA & staining kits) to help scientists detect and quantify small molecules. - Published: 2020-09-22 - Modified: 2025-07-25 - URL: https://www.immusmol.com/ Imaging focus Quick Read Imaging neurotransmitters, not enzymes, receptors, or transporters SR7. PMH ? ? ={}; SR7. PMH = {cn:100,state:false,fn: function { if (_tpt! ==undefined && _tpt. prepareModuleHeight ! == undefined) { _tpt. prepareModuleHeight({id:"SR7_9_3",el:,type:'standard',shdw:'0',gh:,gw:,vpt:,size:{fullWidth:true, fullHeight:false},mh:'0',onh:0,onw:0,bg:{color:'{"orig":"transparent","type":"solid","string":"transparent"}'},plType:'3',plColor:'#4e97fd'}); SR7. PMH. state=true;} else if(SR7. PMH. cn-->0) setTimeout( SR7. PMH. fn,19);}};SR7. PMH. fn; News June 3, 2025New ELISA kit for the Quantification of D-Serine! February 3, 2025Immuno-Oncology: A Practical Toolbox for Quantifying Amino Acid MetabolismNovember 3, 2024New product: Highly Sensitive Citrulline ELISA kit validated for plasma samplesNovember 2, 2024Amino acids in brain health & disease: why and how to measure them easily ? Product highlights New Add to cart / quote ELISA kits 3-Hydroxy-Kynurenine ELISA kit High Sensitivity, Plasma samples (≥ 50µL) € 599 Add to cart / quote ELISA kits D-Serine ELISA kit High Sensitivity, Serum, plasma, CSF, supernatant (≥ 50µL) € 599 -17% Add to cart / quote ELISA kits Global Arginine Bioavailability ratio (GABR) ELISA pack High Sensitivity, Plasma & Serum (≥ 20µL) € 1. 499€ 1. 797 -12% Add to cart / quote ELISA kits Citrulline-to-Arginine ratio ELISA pack High Sensitivity, Plasma & Serum (≥ 20µL) € 1. 049€ 1. 198 Add to cart / quote ELISA kits N8-Acetyl-Spermidine ELISA kit High Sensitivity, Serum, Plasma, Cell Culture Supernatant (≥ 20µL) € 599 Add to cart / quote ELISA kits N1-Acetyl-Spermidine ELISA kit High Sensitivity, Serum, Plasma, Cell Culture Supernatant (≥ 50µL) € 599 -12% Add to cart / quote ELISA kits Arginine-to-Ornithine ratio ELISA pack High Sensitivity, Plasma & Serum (≥ 20µL) € 1. 049€ 1. 198 Add to cart /... --- - Published: 2020-07-03 - Modified: 2020-07-03 - URL: https://www.immusmol.com/product-category/ Surgical Pharmacy Personal Independent Living --- - Published: 2020-04-29 - Modified: 2020-04-29 - URL: https://www.immusmol.com/return-policy/ ReturnsAs of March 1, all PPE, disinfectants, and Corona Virus-related products can't be returned or refunded per our terms of service. These orders are not cancellable with the manufacturers due to high demand. Returns are subject to our acceptance and approval. If an item you received is not the item you ordered, is damaged, or incomplete (missing parts), or defective due to defects in manufacturing please notify is within 7 days by phone, fax, or email to request replacement or refund. If you notify us after 7 days we may accept the return but you will be subject to a 25% restocking fee. If you wish to return an item because it is no longer needed or wanted please contact us in 7 days and subject to our acceptance, we will issue an Return Merchandise Authorization, and you will be refunded minus 25% restocking fee. Shipping fees are not refundable. Fulfillment mistakes that we make resulting in the shipment of incorrect product(s) to you will also be accepted for return 14 days from the date of purchase. Items must be returned in the condition in which they arrived and in their original packaging. Before returning, you must first obtain a Return Merchandise Authorization code within the return period stated above. A 25% restocking fee will apply to all returns that are not defective or fulfillment mistakes. Please be advised that if you discover an error prior to receiving an item purchased or upon receipt you determine an item ordered is... --- - Published: 2020-04-29 - Modified: 2020-04-29 - URL: https://www.immusmol.com/shipping-options/ Your choice In the contiguous United States, our standard shipping fee is $19. 99 for all orders $199. 99 and less. Orders $200. 00 and more, with standard size and standard weight products, have free shipping. Our standard shipping fees only applies to products that are standard size, standard weight, and non-hazardous materials. Hazardous materials products have specific shipping assigned to them or it is calculated after the order based on the fee from the shipping company. Products that are oversized, heavy, or require a freight shipping are excluded from our free shipping offer. Products that are oversized, heavy, or require a freight shipping are: 1) designated outside of our standard shipping fees and have a specific shipping fee assigned to them which shows in the checkout cart or 2) they are designated a product that requires freight shipping. Freight shipping fees are calculated by the freight shipper and are passed on without any increases. Freight shipping is normally calculated based on several variables such as weight, size, delivery method, and delivery location. Standard shipping in the contiguous United States will be provided by Fed Ex Ground or UPS. For additional states and territories in the United States, we have a standard shipping fee of $75. 00. The shipping fee could be higher or lower based on the size and weight of the order. We ship items Monday - Friday within 24 hours of payment provided the product ordered is in stock. Orders are not processed or shipped on Saturday,... --- > While traditional antibodies only recognize large molecules such as proteins, Immusmol designs and develops antibodies capable of targeting low molecular weight entities, below 900 Daltons, that can be used for conventional staining applications as well as in the scope of novel immunoassays development - Published: 2020-04-17 - Modified: 2025-07-11 - URL: https://www.immusmol.com/about-immusmol-company/ About Immusmol Immusmol was initially founded in 2012 in Bordeaux by immunologist Dr. Alban Bessède, to develop anti-hapten antibodies targeting kynurenines for diagnostic and therapeutic applications. Over the past decade, Immusmol speciliazed in the development of antibodies against low molecular weight compounds ( --- - Published: 2020-04-17 - Modified: 2020-04-17 - URL: https://www.immusmol.com/purchase-guide/ Accepted Currency All the prices of courses are in US dollars. We mainly accept payments in US dollars, meanwhile other major currencies are possible but the total amount will vary based on the target exchange rates and tax policies of each country. Account Registering In order to buy any course or become a member of our center, customers/ learners must first register with a personal account providing the following information: Name (required) Age (required) Date of birth (required) Passport/ ID no. (required) Current career (required) Mobile phone numbers (required) Email address (required) Hobbies & interests (optional) Social profiles (optional) Membership Policy Once successfully registered to be a member of our center, users can log in to their account at any time to enjoy hundreds of free & useful lessons. When they purchase a course, their account will be credited with some points. These points will be accumulated to rank users among our membership system. Each level are rewarded with different privileges and discounts. You can check your membership level here. How to Purchase a Course? Click on the Buy this course button, then provide your credit card information to complete the purchase. If you have chosen to save this information, it will automatically be filled out for you to proceed with check-out in just 1 click only. Accepted Credit Cards Visa Mastercards American Express Discover *Taxes are calculated by your local bank and location. Why to Buy our Course? Updated content on a regular basis Secure & hassle-free payment 1-click... --- - Published: 2020-04-17 - Modified: 2020-04-17 - URL: https://www.immusmol.com/terms-of-service/ Legal Disclaimer Seller hereby expressly disclaims all warranties either expressed or implied warranty of merchantability or fitness for a particular purpose. This disclaimer by the seller in no way affects the terms of the manufacturer's warranty if any. Title to goods herein being purchased is retained by the seller until goods are paid for in full by the purchaser and at that time title passes to purchaser. If goods herein being purchased are being purchased for purposes of export, purchaser must obtain from the Federal Government certain export documentation before shipping to a foreign country. In addition, manufacturers' warranties for exported goods may vary or even be null and void. If you have questions, please inquire. Any and all liability is only for the products purchased. Terms & Policies: Basic terms For all prices and products, we reserve the right to make adjustments due to errors, changing market conditions, product discontinuation or typographical errors in advertisements. Allegro is not responsible for manufacturer price changes, which may occur at any time without notice. The product images on this web site may not exactly reflect the product you receive. Design revisions and color variations may exist. Please keep all packing material and documentation in the event that your equipment has to be serviced or returned. Before returning any product, you must obtain a Return Merchandise Authorization (RMA) number. NO returns, of any type, will be accepted without an RMA number. Please have the following information on hand when calling for an RMA... --- > We are committed to protect the security and privacy of your data, as a visitor and as a customer. In compliance with French law n°78-17 and its amendments, as well as Regulations (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on the protection of natural persons with regard to the processing of Personal Data and on the free movement of such data, known as the General Data Protection Regulation (GDPR) for users in the European data region, we thus want to ensure you can access, modify or delete any personal information collected by us. - Published: 2020-04-10 - Modified: 2025-06-26 - URL: https://www.immusmol.com/privacy-policy-2/ Last update: May 23, 2018. Thank you for your interest in Immusmol. We are committed to protecting the security and privacy of your data, as a visitor and as a customer. In compliance with French law n°78-17 and its amendments, as well as Regulations (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on the protection of natural persons concerning the processing of Personal Data and on the free movement of such data, known as the General Data Protection Regulation (GDPR) for users in the European data region, we thus want to ensure you can access, modify or delete any personal information collected by us. This Privacy Policy aims to explain our practices regarding the collection and use of information/data received from you and/or your company. Immusmol website provides prospects, possible customers, and any other people with information regarding our company, activities, and products. The use of the website is subject to this Privacy Policy, which you may at any time print or download. We reserve the right to change this Privacy Policy at any time by updating the revised policy at this location. Information collected and useWe may collect, record, and analyze information about visitors to our website. We may record your IP address and use cookies as well as gather data about visits to the website, including the number of visitors, visits, geo-location data, length of time spent on the site, pages clicked on, or where visitors have come. Furthermore, we may collect... --- --- ## Posts - Published: 2025-06-03 - Modified: 2025-06-20 - URL: https://www.immusmol.com/new-elisa-kit-for-the-quantification-of-d-serine/ Two years after the launch of our L-Serine ELISA kit (already cited in two peer-reviewed publications), our R&D team has now developed a D-Serine ELISA kit, validated for use in human plasma samples. Compatible with any species, and featuring detection limit of 0. 1 µM and a dynamic range of 0. 4 µM to 15. 63 µM, this assay is also well-suited for the quantification of D-Serine in other matrices, including serum, cerebrospinal fluid (CSF), and cell culture supernatants. The D-enantiomer of serine is primarily found in the brain and kidneys. Acting as a co-agonist at NMDA (N-methyl-D-aspartate) receptors, D-Serine plays a key role in synaptic plasticity, memory formation, learning, and neurodevelopment. D-Serine levels are typically reduced in conditions such as schizophrenia (associated with NMDA receptor hypofunction) and elevated in neurodegenerative diseases like Alzheimer’s disease, multiple sclerosis, and amyotrophic lateral sclerosis (ALS). Abnormal D-Serine concentrations have also been observed as potential biomarkers in epilepsy and autism spectrum disorders. In the periphery, D-Serine is metabolized and cleared by the kidneys. Consequently, elevated plasma levels may be indicative of chronic kidney disease (CKD), making it a promising marker for monitoring renal function. In addition to this D-Serine ELISA kit, 2 primary antibodies for each Serine enantiomer are available for imaging applications. Add to cart / quote Amino acids D-Serine Antibody – Rabbit Polyclonal First and only D-Serine antibody validated for IF (brain tissues) €449 New Add to cart / quote Amino acids D-Serine ELISA kit – Plasma, Serum, Supernatant High Sensitivity &... --- - Published: 2025-02-03 - Modified: 2025-06-03 - URL: https://www.immusmol.com/immuno-oncology-a-practical-toolbox-for-quantifying-amino-acid-metabolism/ Cancer cells aggressively reprogram amino acid metabolism to sustain their rapid proliferation and survival. By doing so, they deplete the tumor microenvironment (TME) of essential nutrients—thereby suppressing immune cell function—and generate immunosuppressive metabolites. Over the past decade, Immusmol has developed ELISA kits and primary antibodies targeting key amino acids involved in cancer metabolism and immune modulation, to support research in immuno-oncology. Circulating amino acids as biomarkers in immuno-oncologyFluctuations in amino acids levels in blood or tumor tissues can serve as biomarkers for cancer diagnosis, prognosis or treatment monitoring. To facilitate large-scale studies, we developed a suite of easy-to-use ELISA kits to quantify critical amino acids in plasma and serum samples. Our immunoassays, which were systematically cross-validated by mass-spectrometry, include Glutamine and Glutamate, Tryptophan, Arginine, L-Serine, D-Serine, Asparagine, Lysine, Histidine, and Phenylalanine. In a 2022 Annals of Oncology paper titled “Circulating L-arginine predicts the survival of cancer patients treated with immune checkpoint inhibitors”, our L-Arginine ELISA kit was for instance used to process plasma samples from 77 cancer patients treated with immune-checkpoint blockers. > Explore our amino acid ELISA kitsFocus: assessing Tryptophan metabolism along the kynurenine pathwayEnhanced conversion of Tryptophan to Kynurenine by IDO/TDO enzymes is a hallmark of malignant tumors. This metabolic route is crucial for NAD⁺ synthesis—vital for cancer cell metabolism. Simultaneously, the depletion of Tryptophan and the accumulation of Kynurenine in the TME impair T cell function while promoting immunosuppressive Tregs. To date, over 13 papers have employed Kynurenine-to-Trytpophan ratio ELISA pack to investigate tumor proliferation, immune escape... --- - Published: 2024-11-03 - Modified: 2025-06-04 - URL: https://www.immusmol.com/new-product-highly-sensitive-citrulline-elisa-kit-validated-for-plasma-samples/ Just released, our Citrulline ELISA kit completes our range of ELISA kits designed to assess arginine metabolism and nitric oxide production. Highly sensitive and requiring only a minimal sample volume of 20 µL, the kit has been validated for the quantification of Citrulline in plasma samples. Citrulline is a non-essential amino acid primarily produced in the small intestine by enterocytes, from glutamine and proline. Upon release in the bloodstream, citrulline is transported to the kidneys, where it can be converted into arginine to maintain arginine homeostasis. Citrulline is also synthesized in the liver from ornithine and carbamoyl phosphate, where it participates in the urea cycle (conversion of ammonia into urea for excretion). Finally, citrulline is synthesized by endothelial cells, neurons, and immune cells during the conversion of arginine into nitric oxide, a process that regulates vascular tone, blood flow, neurotransmission, and modulates inflammation. Baseline levels of Citrulline in human plasma range from 20 to 40 μmol/L. With a limit of detection of 1. 47 μmol, cross-validated by LC-MS, our Citrulline ELISA kit constitutes an easy and accurate solution to assess citrulline levels in a wide array of contexts: Diagnosis of Urea Cycle Disorders: Elevated or reduced plasma levels of Citrulline can pinpoint specific enzyme deficiencies within the urea cycle. In certain pathological conditions, elevated citrulline levels are associated with ammonia accumulation, which can alter brain function (confusion, seizures). Biomarker of Gut Integrity: Low plasma levels of citrulline may indicate intestinal failure or damage. In patients with intestinal resections, citrulline can be... --- - Published: 2024-11-02 - Modified: 2025-06-04 - URL: https://www.immusmol.com/amino-acids-in-brain-health-disease-why-and-how-to-measure-them-easily/ Amino acids are critical for brain function. They serve as building blocks for neurotransmitter and protein synthesis, supply energy, detoxify ammonia, modulate synaptic function, and regulate gene expression. Measuring amino acids and their byproducts in blood, urine, or CSF is therefore critical for assessing neurodegenerative diseases, psychiatric disorders, brain tumors, traumatic injury, stroke, as well as rare neurological diseases. Over the past 10 years, our team at Immusmol has developed a range of ELISA kits enabling easy quantification of amino acids in research samples. Highly accurate and specific, our ELISA kits have been cross-validated by LC-MS (data available for each kit). In addition, our team has validated a range of primary antibodies for their visualization in cell cultures, tissue sections, and whole mounts. Here, we provide a quick overview of the role of key amino acids in brain health and disease, and how our tools can help scientists in their detection: L-Arginine (and L-Homoarginine, L-Citrulline, L-Ornithine) Role in Neurobiology Nitric Oxide (NO) production: precursor for nitric oxide (NO), a critical neurotransmitter and vasodilatator, influencing cerebral blood flow, synaptic plasticity, learning, and memoryPolyamine synthesis (putrescine, spermidine, spermine): regulating neural growth & differentiation Brain pathologies Neurodegenerative diseases: dysregulated NO leads to oxidative stress in Alzheimer’s and Parkinson’sStroke: excessive NO exacerbates neuronal damage during ischemiaUrea cycle disorders: elevated levels or metabolic deficiencies in arginine metabolites (Citrullinemia, Ornithine Transcarbamylase Deficiency) lead to hyperammonemia, causing lethargy, seizures, and cognitive impairmentBrain tumors: excess of NO and polyamines often correlates with brain tumor malignancy (angiogenesis, aggressiveness, resistance... --- - Published: 2024-08-04 - Modified: 2025-06-04 - URL: https://www.immusmol.com/measuring-the-kynurenine-to-tryptophan-ratio-by-elisa-highlights-from-our-customers-research/ Ten years ago, we introduced the first research ELISA kits designed to easily measure Kynurenine (Kyn) and Tryptophan (Trp) concentrations in biological fluids. With a minimal sample volume requirement of just 20 µL, our kits have been widely used to calculate the kynurenine/tryptophan ratio in various sample types, including cell culture supernatants, blood samples, and tissue homogenates from both animal and human origins. Here, we highlight key applications and research achievements made by our customers using our ELISA kits. Infectious diseasesInfluenza: In 2021, a US team documented the reduction of kynurenine pathway metabolism in the plasma of critically ill patients, as well as in the lungs of aged mice infected with influenza. Read paperTuberculosis/HIV co-infection: In 2020, Gascua Adu-Gyamfi et al. established plasma kynurenine/tryptophan ratio as a diagnostic biomarker of pulmonary tuberculosis in both HIV-infected and uninfected individuals. The team compared our ELISA kit to MS, and recommended the ELISA approach for frontline clinical diagnosis. Results were confirmed in a 2021 study in pregnant women living with HIV. Venezuelan equine encephalitis virus: In 2024 paper, a team from the University of Texas measured the KYN/TRP ratio in brain homogenates of mice infected with Venezuelan equine encephalitis virus (VEEV), demonstrating elevated IDO1 activity correlated with cognitive impairment. HIV & diffuse large B-cell lymphoma: A 2024 study in 76 patients with Diffuse large B-cell lymphoma (DLBCL) reported elevated plasma Kynurenine to Tryptophan ratio, especially in patients with HIV. Neurological & psychiatric disordersSchizophrenia: in 2021, a Spanish team investigated tryptophan metabolism along the... --- - Published: 2024-08-01 - Modified: 2025-06-04 - URL: https://www.immusmol.com/new-product-highly-sensitive-melatonin-elisa-kit-for-serum-and-plasma-samples/ Our range of ELISA kits for quantifying tryptophan metabolites welcomes a new addition: Melatonin. This highly sensitive ELISA kit enables the measurement of melatonin levels in plasma and serum samples both during daytime and nighttime. Primarily synthesized from Serotonin in the pineal gland during nighttime, Melatonin is then released in the bloodstream. During the day, Melatonin concentrations in the blood range from 0 to 20 pg/mL. They peak at night, reaching 40 to 100 pg/mL. With a limit of detection of 1. 6 pg/ml, and a range of 0/3 to 300 pg/ml, our Melatonin ELISA kit is thus suitable for most applications. Obviously of interest for the study of circadian rhythm disorders, the measurement of Melatonin concentrations in blood is relevant in other scientific areas:Aging: Melatonin secretion progressively declines with age. Research suggests that melatonin have protective effects against aging and its associated symptoms, including cardiovascular and neurodegenerative disorders. Mood disorders: Melatonin secretion can be altered in depressive and bipolar disorders, affecting the onset, duration, and offset of synthesis. Reproductive health: Melatonin levels influence menstrual cycles, fertility, and fetal development during pregnancy. Immuno-Oncology: Melatonin displays anti-cancer effects by modulating the immune system, acting on various immune cells within the tumor microenvironment (T cells, Tregs, NK cells, and macrophages). Metabolic Disorders: Low plasma concentrations of melatonin are often found in diabetes and obesity. The hormone has shown beneficial effects on metabolic, inflammatory, and neuropsychiatric symptoms. Learn more about our Melatonin ELISA kit --- - Published: 2024-07-08 - Modified: 2025-06-04 - URL: https://www.immusmol.com/webinar-on-july-17th-dive-into-highly-multiplexed-3d-spatial-biology-with-the-insihgt-approach/ Over the past decade, the team of Hei Ming LAI, MD, at The Chinese University of Hong Kong has developed next-gen 3D histology methods for clinical and research use, published in Nature Methods, Nature Communications, ACS Applied Nano Materials, and Neuropathology and Applied Neurobiology. In this 30-minute webinar, Dr Hei Ming LAI presents a newly developed method for highly multiplexed 3D histology – INSIHGT. His team tested 323 antibodies (including Immusmol antibodies to neurotransmitters), 21 lectins, and fluorescence in situ hybridization (FISH) with INSIHGT. Read their paper on BioRxivhttps://youtu. be/l1OJ9p1rU5A --- - Published: 2024-07-05 - Modified: 2025-06-04 - URL: https://www.immusmol.com/serotonin-elisa-kits-for-research-applications-a-literature-review/ Anxiety and depression, autism, cognitive decline, gut motility and intestinal inflammation disorders, ... Abnormal serotonin levels are detected in a wide range of pathophysiological conditions. Over the past 10 years, researchers have been using our Serotonin ELISA kits to assess 5-hydroxytryptamine (5-HT) concentrations in various types of samples: cell culture supernatant, gut and brain homogenates, as well as serum and plasma samples. Here's a short review of the papers released by our customers: Low Plasma & Brain Serotonin Levels in Autism, Anxiety & Depression Carpita et al. reported in 2023 reduced plasma levels of 5-HT in adults with Autism Spectrum Disorder (ASD). Letenneur et al. described in 2023 a drop in serum serotonin levels and higher Kynurenine-to-Tryptophan ratio in a mouse model of chronic stress-induced anxiety. This situation wasn't observed in mice supplemented with a mix of Lactobacillus strains, which were better able to cope with chronic stress. Sabti et al. found in 2019 that antidepressant compounds increase serotonin levels in the brain in the TST stress-induced mouse model. In 2021, Sasaki et al. obtained the same results. This secretion profile was also measured via intracerebral in vivo microdialysis. Measurement of Serotonin Concentrations in the Brain to Assess Cognitive Decline In 2023, Aktar et al. measured hippocampal concentrations of serotonin, dopamine, and noradrenaline in the senescence-accelerated mouse model SAMP8. Low neurotransmitter levels were associated with age-related memory and spatial impairment. The oral administration of a plant alkaloid elevated neurotransmitter release and improved cognitive parameters. In 2020, Iwata et al. had... --- - Published: 2024-06-10 - Modified: 2024-06-10 - URL: https://www.immusmol.com/dopamine-quantification-a-webinar-on-midbrain-organoid-models-of-parkinsons-disease/ On June 19th, Immusmol hosted a webinar about midbrain organoid models of Parkinson's disease. Prof. Jens Christian Schwamborn (LCSB / OrganoTherapeutics) presented his team's recently published work, describing a novel patient-derived organoid model of Parkinson's disease. In this 30-minute webinar, Prof. Schwamborn discussed this publication, explaining how this model was generated and which endpoints were examined — including dopamine release measured by ELISA — to assess physiological relevance. https://youtu. be/UgcbK8wBOTg Learn more: About the work of Jens Christian Schwamborn: LSCB team / OrganoTherapeutics (co-founded in 2019) Immusmol's dopamine ELISA kit used to quantify dopamine release in midbrain organoids About neurotransmitter imaging with Immusmol's primary antibodies to dopamine, serotonin, GABA, Glutamate, and more. --- - Published: 2024-04-30 - Modified: 2025-06-05 - URL: https://www.immusmol.com/back-from-istry-2024/ Alban, our CEO, was in Germany on April 24-26th to attend the 16th meeting of the International Society for Tryptophan Research! This biennial conference brought together research teams interested in the degradation of tryptophan, along the kynurenine and serotonin pathways, in Jena. Generally linked to immunology, the disciplines represented at ISTRY 2024 included oncology, virology, psychiatry, nutrition, aging, and neurodegeneration. A longtime member and sponsor of the ISTRY, Alban went to the conference with a special T-shirt : ELISA kits to quantify Tryptophan metabolism Antibodies to visualize Tryptophan metabolites --- - Published: 2024-04-10 - Modified: 2025-06-05 - URL: https://www.immusmol.com/imaging-neurotransmitters-not-enzymes-receptors-or-transporters/ Dopamine, Serotonin, GABA, Glutamate, Histamine, Norepinephrine, Serine, Octopamine, ... To generate spatial information about key neuromodulators and neurotransmitters, neurobiologists typically perform stainings against enzymes (e.g. TH for dopamine, GAD65-67 for GABA), receptors (e.g. Glutamate) or transporters (e.g. Norepinephrine, Glutamate). Why? Dopamine, Serotonin, GABA, Glutamate, Histamine, Norepinephrine, Serine, Octopamine, ... To generate spatial information about key neuromodulators and neurotransmitters, neurobiologists typically perform stainings against enzymes (e. g. TH for dopamine, GAD65-67 for GABA), receptors (e. g. Glutamate) or transporters (e. g. Norepinephrine, Glutamate). Why? Simply because highly specific antibodies against neuromediators weren’t available until recently. Our team developed and IF/IHC-validated 17 primary antibodies to key neurotransmitters. These antibodies were already used in 20+ papers. Take a look below. And for easy quantification, see our ELISA kits to neurotransmitters. Staining for neurotransmitters: a few pictures Dopamine (green) & Serotonin (red) in embryonic mouse brain (whole mount) Immunostaining in the CNS of embryonic mouse E13. 5 using STAINperfect kit and primary antibodies to Dopamine (IS1005 – green) and Serotonin (IS1035 -red) GABA (green) & MAP2 (red) in adult mouse primary cortical neurons Immunodetection of MAP2 (red) and GABA (green) mouse primary cortical cultures, using anti-GABA IS1006 antibody and the STAINperfect immunostaining kit. L-Glutamate (green) & MAP2 (red) in mouse cortical primary neurons Immunodetection of L-Glutamate (green) and MAP2- (red) positive neurons in mouse primary cortical culture reveals the presence of L-Glutamate within fibers and soma of neurons (IS1001 anti-glutamate rabbit pAb) L-Serine (green) & GABA (red) in primary cortical neurons (mouse) Primary mouse cortical neurons were stained using anti-L-Serine (green) polyclonal rabbit antibody (IS1003) and anti-GABA (red) chicken polyclonal antibody (IS1036) using the STAINperfect immunostaining kit A. Octopamine (green) & Serotonin (red) in crayfish eyestalk Immunostaining of crayfish eyestalk using anti-octopamine rabbit polyclonal... --- > TH expression does not necessarily indicate that neurons are metabolically active and produce dopamine. Therefore, several groups interested in organoid-based modeling of Parkinson’s disease have combined standard markers of dopaminergic neurons, such as TH and GIRK2, with direct staining of dopamine using anti-hapten antibodies, as well as ELISA kits for quantifying dopamine release in supernatant. - Published: 2024-03-12 - Modified: 2025-06-05 - URL: https://www.immusmol.com/beyond-th-imaging-dopamine-content-in-midbrain-organoids-for-parkinsons-disease-modeling/ TH expression does not necessarily indicate that neurons are metabolically active and produce dopamine. Therefore, several groups interested in organoid-based modeling of Parkinson’s disease have combined standard markers of dopaminergic neurons, such as TH and GIRK2, with direct staining of dopamine using anti-hapten antibodies, as well as ELISA kits for quantifying dopamine release in supernatant. Since the early papers describing the generation of stem cell-derived midbrain organoids in 2016-2017, research teams have aimed to demonstrate the presence of functional dopaminergic neurons in these 3D microtissues. One widely trusted and accepted marker for dopaminergic function is tyrosine hydroxylase (TH) – the enzyme converting L-Tyrosine into L-Dopa, the precursor of Dopamine. However, TH expression does not necessarily indicate that neurons are metabolically active and produce dopamine. Therefore, several groups interested in organoid-based modeling of Parkinson’s disease have combined standard markers of dopaminergic neurons, such as TH and GIRK2, with direct staining of dopamine using anti-hapten antibodies, as well as ELISA kits for quantifying dopamine release in supernatant. Five selected articles demonstrating dopamine biosynthesis in human midbrain organoids Seminal paper (>350 citations) describing the 3D differentiation of human neuroepithelial stem cells into midbrain-specific organoids containing dopamine-producing neurons at day 50 post-differentiation In 2017, the group of Jens Schwamborn from the Luxembourg Centre for Systems Biomedicine (LCSB) released one of the first protocol to generate stem-cell derived midbrain organoids. The team demonstrated the presence of midbrain-specific dopaminergic neurons at day 50 post-differentiation, using markers such as TH, TUJ1, GIRK2, CALBINDIN, Dopamine transporter, as well as dopamine itself, using the IS1005 antibody. See picture Monzel et al. Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells. Stem Cell Reports. 2017 May 9;8(5):1144-1154. doi: 10. 1016/j. stemcr. 2017. 03. 010. Epub 2017 Apr 13. Midbrain organoid whole mount stainings of TH & dopamine, and quantification of dopamine release at day 70... --- > Serotonin (5HT) is one of the most potent monoamine neurotransmitters and peripheral signaling molecules. Therefore, tools allowing for the evaluation of serotonergic systems are valuable to approach the complex 5HT activities in physiological and pathological situations, but also to investigate mechanisms of action of novel disease-targeting therapies. For this purpose, we have set up and validated a series of experimental immunoassays specifically raised against 5HT. - Published: 2023-10-03 - Modified: 2025-06-05 - URL: https://www.immusmol.com/reveal-serotonin-in-your-samples/ Serotonin (5HT) is one of the most potent monoamine neurotransmitters and peripheral signaling molecules. Therefore, tools allowing for the evaluation of serotonergic systems are valuable to approach the complex 5HT activities in physiological and pathological situations, but also to investigate mechanisms of action of novel disease-targeting therapies. For this purpose, we have set up and validated a series of experimental immunoassays specifically raised against 5HT. Scientific backgroundSerotonin (5-hydroxytryptamine, 5HT) is one of the most potent monoamine neurotransmitters and peripheral signaling molecules able to act as a paracrine, endocrine, and exocrine messenger. While blood platelets only rely upon 5HT uptake for their stores, serotonergic neurons and gastrointestinal enterochromaffin cells can both uptake and synthesize 5HT from its amino acid precursor - L-tryptophan. Serotonin is also synthesized in the pineal gland as a precursor of melatonin. Physiologically, 5HT has complex and diverse effects on the central and peripheral nervous systems, as well as on neuroendocrine regulation and immunological responses. However, it is also involved in the biochemistry of several pathophysiological conditions including many neurological disorders, gastrointestinal dysregulations, and cancer. Our antibodies and ELISA kitsTherefore, tools allowing for the evaluation of serotonergic systems might be valuable to approach the complex 5HT activities in physiological and pathological situations, but also to investigate mechanisms of action of novel disease-targeting therapies. For this purpose, we have set up and validated a series of experimental immunoassays specifically raised against 5HT; either ELISA kits for the determination of 5HT content (#BA-E-8900, #BA-E-8900R), or antibodies to approach its localization and functional networks (#IS1086, #IS1035, #IS040, #IS1007). Our tools are compatible with varied types and natures of samples, originating from different species. Illustrative data Cancer cell lines display a differential serotonin production activity. (A) To characterize their ability to synthesize serotonin, a series of human tumor cell lines were seeded and left untreated or treated with the tryptophan hydroxylase 1 inhibitor – telotristat. Culture supernatants... --- > Polyamines are molecules derived from ornithine (putrescine, spermine, spermidine, etc.) or arginine (agmatine, etc.). Given the importance of polyamine metabolism in cancer progression and resistance to treatment, robust tools are needed to investigate this pathway. To this aim, we developed and validated the first ELISA kits able to quantify ornithine, N1-acetylspermidine and N8-acetylspermidine in samples of different natures (plasma, cell culture supernatants) and different species (mouse, human). - Published: 2023-09-07 - Modified: 2025-06-05 - URL: https://www.immusmol.com/assessing-the-polyamine-pathway-through-immunoassays/ Given the importance of the polyamine pathway in cancer progression and resistance to treatment, investigating it requires robust tools. To this aim, we developed and validated the first ELISA kits to quantify ornithine, N1-acetylspermidine, and N8-acetylspermidine in samples of different natures (plasma, cell culture supernatants) and different species (mouse, human). Scientific backgroundPolyamines are molecules derived from ornithine (Orn) (i. e. , putrescine, spermine, spermidine) or arginine (Arg) (i. e. , agmatine). They are present in mammalian cells at millimolar concentrations1. Key regulatory steps of their metabolism are represented by ornithine decarboxylase (ODC), acetyl-CoA:spermidine/spermine N1-acetyltransferase (cSAT), acetylCoA:spermidine-N8-acetyltransferase (nSAT), and membrane transport systems. While ODC is responsible for ornithine degradation and spermidine production, cSAT and nSAT transform spermidine to N1- and N8-acetylspermidine (N1- and N8-AcSpdn), respectively. These molecules are involved in many critical processes such as cell proliferation, nucleic acid synthesis, and cytoprotection from oxidative stress2. Several studies have evidenced that polyamine metabolism is frequently increased in cancer3, which can fuel tumor progression4 and favor immune escape5. Elevated levels of polyamines in sera of cancer patients have been demonstrated to correlate with poor prognosis6. Our new ELISA kitsGiven the importance of this metabolic pathway in cancer progression4 and resistance to treatment7, investigating it requires robust tools. To this aim, we developed and validated the first ELISA kits to quantify ornithine (#IS-I-1000R), N1-acetylspermidine (#IS-I-2400R), and N8-acetylspermidine (#IS-I-2500R) in samples of different natures (plasma, cell culture supernatants) and species (mouse, human). Illustrative dataOur immunoassay specifications were first determined by comparing quantified analyte levels, in the same plasma samples, using conventional mass spectrometry and our ELISA kits (Figure 1), thus validating the technological platform. Finally, using these immunoassays, we evaluated the levels of the three analytes in cell culture supernatants from MC38 (mouse, colon), 4T1 (mouse, breast), HCT116 (human, colon) and BT549 (human, breast) tumor... --- > Serotonin (5-HT) is one of the most potent monoamine neurotransmitters and peripheral signaling molecules. Physiologically, 5-HT has complex and diverse effects on the central and peripheral nervous systems, neuroendocrine regulation, and immunological responses. We recently developed and added to our catalog a novel antibody raised against 5-HT, compatible with formalin-fixed biological materials. - Published: 2023-06-22 - Modified: 2025-06-05 - URL: https://www.immusmol.com/a-newcomer-to-our-antibodies-portfolio-for-serotonin-imaging-on-ffpe-samples/ Serotonin (5-HT) is one of the most potent monoamine neurotransmitters and peripheral signaling molecules. Physiologically, 5-HT has complex and diverse effects on the central and peripheral nervous systems, neuroendocrine regulation, and immunological responses. We recently developed and added to our catalog a novel antibody raised against 5-HT, compatible with formalin-fixed biological materials. Serotonin (5-hydroxytryptamine, 5-HT) is one of the most potent monoamine neurotransmitters and peripheral signaling molecules able to act as paracrine, endocrine, and exocrine messenger, and found stored in three main cell types. While serotonergic neurons in the nervous system and intestinal myenteric plexus, and enterochromaffin cells in the mucosa of the gastrointestinal tract can both uptake and synthesize 5-HT from its precursor “L-tryptophan”, blood platelets only rely upon 5-HT uptake for their stores. Serotonin is also synthesized in the pineal gland as a precursor of melatonin. Physiologically, 5-HT has complex and diverse effects on central and peripheral neromodulation, neuroendocrine regulation, and immunological responses. In addition, it also plays an important part in the biochemistry of many pathophysiological conditions including depression, migraine, bipolar disorder, anxiety, gastrointestinal dysregulations, and cancer. Therefore, evaluating serotonergic contents and their functional expression is critical to approach the complex 5-HT activities and requires compatible experimental tools. We thus recently developed and added to our catalog a novel antibody raised against 5-HT (#IS1086, polyclonal), compatible with formalin-fixed biological materials. While allowing for the specific immunodetection of the serotonergic systems, our antibody has been validated for its use through immunochemistry and immunofluorescence applications on formalin-fixed paraffin-embedded (FFPE) samples originating from different species. Figure 1 – Serotonergic neurons of the Raphe nucleus through a FFPE mouse brainstem coronal section revealed by anti-serotonin (5-HT, rabbit polyclonal antibody #IS1086) and Microtubule-Associated Protein-2 (MAP2) immunohistofluorescence. 5-HT immunoreactivity highlights well the 5-HT-containing neurons of the dorsal and median Raphe nuclei (DRN and MRN, respectively).... --- > Given the importance of the Arginase pathway in pathophysiological processes, we have developed and validated a robust and easy-to-use immunoassay for the simultaneous detection and quantification of both L-Arginine and L-Ornithine in plasma / serum - Published: 2023-05-22 - Modified: 2025-06-05 - URL: https://www.immusmol.com/assessing-arginase-activity-through-an-easy-to-use-immuno-assay-now-possible/ Given the importance of the Arginase pathway in pathophysiological processes, we have developed and validated a robust and easy-to-use immunoassay for the simultaneous detection and quantification of both L-Arginine and L-Ornithine in plasma / serum. Free L-Arginine (Arg) is provided by the diet, de novo synthesis, and protein turnover. De novo synthesis is important enough not to consider Arg as an essential amino acid. However, in some circumstances – e. g. early development, infection, and inflammation – de novo synthesis is not sufficient and requires dietary Arg, which is thus classified as a conditionally-essential amino acid. Whatever the source, Arg can be metabolized through different degrading pathways which include i) the nitric oxide synthase (NOS) pathway providing Citrulline and NO, as well as ii) the well-known Arginase pathway leading to the production of Urea and L-Ornithine (Orn). In mammals, through a limited amount of Arg and the concomitant production of Orn, elevated Arginase activity has been linked to dysfunctions and pathologies of the cardiovascular system, kidneys, and central nervous system as well as to dysfunction of the immune system and cancer (1). In the context of oncology, Arginase – types 1 & 2 – can be expressed by tumor cells or immune cell subsets including Myeloid Derived Suppressive Cells (MDSCs), and, through its metabolic activity, creates an immunosuppressive milieu. As to restore an effective anti-tumor immune response, blocking the Arginase pathway has been considered an attractive immunotherapeutic strategy (2). Given the importance of this metabolic pathway in pathophysiological processes and in particular in immune regulation, we have developed and validated a robust and easy-to-use immunoassay (#ISE-0410R) for the simultaneous detection and quantification of both Arg and Orn in plasma / serum from multiple species. Immuno-assay... --- - Published: 2022-12-01 - Modified: 2025-06-05 - URL: https://www.immusmol.com/quantification-of-l-arginine-in-various-samples-made-simple/ L-Arginine is a key amino acid in the immune regulation and can be targeted as part of an anti-tumor response. We have thus developed and validated an ELISA kit for the detection and quatification of L-Arginine in biological samples. Immunometabolism is known to play a key role in shaping the immune system. Amino acid degradation by tumor and/or suppressive immune cell subsets has been shown to limit anti-tumor immune response (1) and, in this era, L-Arginine (Arg) figures as one of the keystones (2). Indeed, Arg can be degraded within the tumor microenvironment (TME) via Arginase (types 1 & 2) expressed by tumor cells or immune cell subsets including Myeloid Derived Suppressive Cells (MDSCs), which catabolize it into Ornithine plus Urea. Thus, blocking Arginase represents an attractive therapeutic strategy to restore Arg level within the TME and favor the initiation of an effective anti-tumor immune response (3). Given the importance of this amino acid in immune regulation, we developed and validated a robust and easy-to-use immunoassay (#IS-I-0400R) for the detection and quantification of Arg in several biological sample types, eg. plasma, cell culture supernatants and tumor interstitial fluid (TIF). Using a syngeneic MC38 mouse colorectal tumor model along with our immunoassay, we evaluated Arg level within sera and TIFs upon animal treatment with the prototypical Arginase inhibitor, ie. INCB-1158, or with its respective vehicle solution for one or five days. In line with the literature (4), this assay revealed the ability of INCB-1158 to restore Arg level in the periphery (sera) and within the tumor (TIFs), an effect more visible with a longer treatment period. This dataset confirms the robustness of our ELISA kit to quantify Arg in complex biological samples and enlighten Arg metabolism-modulating effects. Figure 1 –... --- - Published: 2022-10-18 - Modified: 2025-06-10 - URL: https://www.immusmol.com/antibodies-to-neurotransmitters-as-tools-to-evaluate-the-transmission-network-function-by-immunofluorescence/ Glutamate (Glu) and gamma-aminobutyric acid (GABA) are the major neurotransmitters (NTs) in the brain and work together through balanced interactions to control many processes. Imbalanced interactions can cause diseases, that impair intracellular contents of Glu and GABA as well as their anatomical and functional network. Glutamate (Glu) and gamma-aminobutyric acid (GABA) are the major neurotransmitters (NTs) in the brain. Being respectively the most common excitatory and the chief inhibitory NTs, Glu and GABA work together through balanced interactions to control many processes, e. g. the overall brain excitation level, and thus maintain homeostasis. However, while prolonged imbalance in glutamatergic and/or GABAergic signaling transmissions is often associated to diseases, such as autism spectrum disorders, neuropsychiatric and mood disorders, and schizophrenia, NT levels can also be affected by external factors and by autoimmunity and genetic disorders. In those diseased conditions, intracellular contents of Glu and GABA as well as their anatomical and functional network are found impaired. Therefore, evaluating anatomo-phenotypic and functional Glu and GABA transmission is critical to address these networks, and thus requires appropriate experimental tools. To this end, we thus developed and validated antibodies directed against Glu (#IS1001, polyclonal) and GABA (#IS039, monoclonal, and #IS1006, polyclonal). While allowing for the selective immunocytochemical visualization of the putative glutamatergic and GABAergic system networks, our antibodies are perfectly suitable to evaluate these NT-related networks / functions. Figure 1: GABAergic neuronal network in a mature rat cortical culture revealed through GABA immunoreactivity detection using either our mouse monoclonal GABA antibody (#IS039) in green or rabbit polyclonal GABA antibody (#IS1006) in red, with the STAINperfect immunostaining kit A. GABAergic network is identically revealed by both antibodies (yellow on the overlay) which evidence the cortical GABAergic neurons as well as their rich and dense neuritic extensions. Figure 2: GABAergic network... --- - Published: 2022-09-29 - Modified: 2025-06-10 - URL: https://www.immusmol.com/l-histidine-a-newcomer-to-our-elisa-kits-portfolio/ We developed and validated a new L-Histidine ELISA kit (#IS-I-1300R) which allows for L-His quantitation in plasma samples. The assay requires a low sample volume of 10μL and is characterized by a 1.4µM sensitivity. L-Histidine (His) is an essential amino acid displaying a unique properties profile, involved in a number of biological activities, e. g. in pH buffering, in metal ion chelation, and in oxidative species scavenging, which confer it many physiological properties as antioxidant, anti-inflammatory, and in erythropoiesis and immune system regulation (1). While there are several pathways of His degradation, most catabolism is directed to protein turnover and glutamate production and begins with histidase-dependent deamination. Also, the minor pathways of His as a precursor of histamine and His-rich proteins and peptides make it unique among other amino acids (1). As a nutritionally essential amino acid, a deficiency of His has been shown to reduce protein levels in plasma, which in turn reduced the immunity defense (2). In contrast, dietary His supplementation has recently been reported for its role in the immune system homeostasis (3), and for many demonstrable potential benefits in various clinical conditions, including cognitive and neurological disorders, metabolic and inflammatory syndromes, and malignancies (1). Plasma His levels have even been shown as specific biomarkers for intestinal mucosal damage in calves (4). Interestingly, His supplementation was recently shown to increase chemotherapeutic sensitivity in pediatric leukemia-bearing mice, an effect mediated by an increase of histidine degradation flux (5), thus suggesting that His supplementation may improve the effectiveness of therapeutic treatments in cancer patients (6, 7). As relevant to the above, His emerges as a key amino acid whose level measurements would be valuable in many pathophysiological conditions. We have thus developed and... --- - Published: 2022-09-06 - Modified: 2025-06-10 - URL: https://www.immusmol.com/spotlight-from-annals-of-oncology/ New highlight in Annals of Oncology! In this study, Peyraud at al. show that plasmatic level of L-Arginine (Arg) is associated with clinical outcome of patients treated with immune checkpoint blockers (ICB). Using an ELISA approach for Arg quantification (#IS-I-0400R) applied on two independent cohorts, authors demonstrated that low plasmatic level of Arg was associated with a worse clinical outcome. In the era of immuno-oncology, identification of reliable predictive biomarkers – that can help for a better selection of cancer patients who might respond to Immune Checkpoint Blockers (ICB) – remains crucial. Expression of PD-L1 on cancer cells, high micro satellite instability, and tumor mutational burden are, to date, the only predictors of ICB response while still being imperfect (1). Even though tumor tissue profiling is key for biomarker discovery, insights from the periphery are needed in order to allow an easy-to-implement clinical practice. Immunometabolism is known to play a key role in shaping the immune response. Amino Acid degradation by tumor and/or suppressive immune cells has been shown to limit anti-tumor immune response (2, 3). In a recent study – supervised by Antoine Italiano and conducted in collaboration between teams from Explicyte (Bordeaux, France), Institut Bergonié (Bordeaux, France), and Institut Gustave Roussy (Villejuif, France), and published in Annals of Oncology (4)- plasmatic level of L-Arginine (Arg) has been found to be associated with clinical outcome of advanced cancer patients treated with ICB. Using an ELISA approach for Arg quantification (#IS-I-0400R) applied on two independent cohorts, Peyraud et al. demonstrated that low plasmatic level of Arg was associated with a worse clinical outcome. As a new product on the market, our novel ELISA kit for Arg quantification (#IS-I-0400R) requires as little as 20µL plasma sample volume and therefore offers a valuable and easy approach to predicting sensitivity of patients to ICB before treatment onset. Arg metabolism is predictive of anti-PD(L)1... --- - Published: 2022-06-23 - Modified: 2025-06-10 - URL: https://www.immusmol.com/get-a-comprehensive-and-easy-to-access-evaluation-of-the-kynurenine-pathway-by-elisa/ Among mechanisms associated with cancer immune evasion, the activation of the Kynurenine Pathway (KP) is known to play a key role and has thus been proposed as a therapeutic target to improve current immune checkpoint blockade-based immunotherapies. Among mechanisms associated with cancer immune evasion, the activation of the Kynurenine Pathway (KP) is known to play a key role and has thus been proposed as a therapeutic target to improve current immune checkpoint blockade-based immunotherapies (Peyraud et al. , 2022). The first step of this pathway relies on the activation by inflammatory stimuli (eg. IFNg, IL6, ... ) of Tryptophan degrading enzymes including IDO1/2 (indoleamine 2,3 dioxygenase) and TDO2 (Tryptophan 2,3 dioxygenase). L-Kynurenine is the first stable metabolite of the KP and can be transformed into a series of metabolites collectively known as Kynurenines and which include among others 3-OH Kynurenine, Kynurenic (KynA), Xanthurenic and Quinolinic (Quin) acids. While the quantification of Kynurenine (Kyn), Tryptophan (Trp) and their related ratio has been widely evaluated in samples from cancer patients, little is known for the other metabolites. We developed and validated new and easy-to-use immunoassays for the quantification of KynA and Quin, and evaluated their respective abundance in plasma from cancer patients and healthy subjects – KynA to Quin ratio was also calculated. While plasmatic contents of both KynA and Quin were increased in cancer patients compared to healthy subjects, the ratio did not differ thus arguing for the whole KP activation instead of a preferred axis. Plasma samples from healthy subjects (n=49) and cancer patients (n=106) were processed for the quantification, through immunoassays, of Kyn (BA-E-2200R), Trp (BA-E-2700R), KynA (IS-I-0200R) and Quin (IS-I-0100R). Each metabolites and ratios – Kyn/Trp & KynA/Quin – are presented as both individual values... --- - Published: 2022-05-05 - Modified: 2025-06-10 - URL: https://www.immusmol.com/new-arrival-in-our-amino-acid-elisa-kits-portfolio-l-asparagine-quantification-made-easy/ We developed and validated a new L-Asparagine ELISA kit (#IS-I-1600R) which allows for L-Asn quantitation in plasma samples. The assay requires a low sample volume of 20μL and is characterized by a 2.3µM sensitivity. L-Asparagine is a conditionally non-essential amino acid that can be produced in our body. However, Asparagine (Asn) is essential for the growth of highly proliferative cells such as cancers and it must be provided by the environment. Targeting Asparagine using recombinant Asparaginase – as to deprive tumor cells of an important energetic source – thus represents an attractive target and has been for instance approved for the treatment of Acute Lymphoblastic Leukemia (1). Also, while targeting Asn metabolism figures as an attractive therapeutic avenue, Asn level constitutes a valuable biomarker. Indeed, among other evidences, it has been shown that quantification of Asn nicely discriminates healthy subjects from patients with Epithelial Ovarian Cancer (2). More recently, increased Asn level has been linked to poor survival in female patients with colorectal cancer (3). Altogether, this set of information motivated our interest in developing a robust immuno-assay to accurately quantify Asn in biological fluids. We finally developed and validated a novel ELISA kit (#IS-I-1600R) for Asn quantitation in plasma samples – an assay requiring a sample volume as low as 20μL and characterized by a limit of detection of 2. 3µM and a limit of quantification 4. 4µM. Sensitive & easy-to-implement Typical standard curve obtained with the Asn ELISA kit (#IS-I-1600R) where the optical density is inversely correlated with Asn concentration within a range of 4. 4µM – 375µM. Cross-validated with LC/MS Asn was quantified in human EDTA plasma samples from 40 subjects using IS-I-1600R ELISA kit and by LC/MS. Correlation between both... --- - Published: 2022-03-30 - Modified: 2025-06-10 - URL: https://www.immusmol.com/126-news-kynurenine-tryptophan-elisa-pack-recently-cited-in-cancer-discovery-html/ Our Kynurenine/Tryptophan ELISA pack recently cited in Cancer Discovery in a publication written by Marta Galan-Diez et al. In this occasion, benefit from the spring sale on our Kynurenine / Tryptophan ELISA pack until April 30! Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia Cancer Discovery, Jan 19, 2022 Marta Galan-Diez, Florence Borot, Abdullah Mahmood Ali, Junfei Zhao, Eva Gil-Iturbe, Xiaochuan Shan, Na Luo, Yongfeng Liu, Xi-Ping Huang, Brygida Bisikirska, Rossella Labella, Irwin Kurland, Bryan L Roth, Matthias Quick, Siddhartha Mukherjee, Raul Rabadan, Martin Carroll, Azra Raza, Stavroula KousteniIn this study, Authors highlight the role of the bone marrow niche in the pathogenesis, maintenance and resistance to treatment of hematologic malignancies through both the Kynurenine and Serotonin pathways. In particular, Kynurenine secreted by Acute Myeloid Leukemia (AML) promotes, via the activation of 5HTR1B expressed in osteoblasts, a pro-inflammatory state associated with the production of Serum Amyloid A (SAA), which in turns entertains IDO1 expression and activity thereby promoting AML progression. This outstanding work underlines a new KYN–5HTR1B–SAA– IDO axis participating in AML progression and figures as an innovative therapeutic target. In this study, Tryptophan and Kynurenine levels were measured in plasma samples using ImmuSmol ELISA kits (# ISE-2227). Shop Kynurenine-to-Tryptophan ratio ELISA pack --- - Published: 2022-03-10 - Modified: 2025-06-10 - URL: https://www.immusmol.com/124-news-immusmol-products-trusted-by-scientists-and-highlighted-in-recent-publications-html/ ImmuSmol products trusted by scientists and highlighted in recent publications! Discover the recent studies where some of our top products have been used and have helped advance research. Always more publications citing our products ! Here below brief descriptions of recent features studies where some of our top products have been used and have helped advance research. Indoleamine 2,3-dioxygenase (IDO)-1 and IDO-2 activity and severe course of COVID-19Guo et al. , Journal of Pathology, 2022In this work, the authors demonstrated the engagement of the Kynurenine pathway – through IDO2 – in heart, lung and brain from COVID-19 patients. In particular, they demonstrated through the use of ImmuSmol antibodies and immunohistochemistry, the accumulation of key metabolites including 3OH-Anthranilic Acid (# IS001) and Quinolinic Acid (# IS1010). Endogenous produced catecholamines improve the regulatory function of TLR9-activated B cellsHonke et al. , Plos Biology, 2022Authors nicely presented the ability of B cells to produce catecholamines upon Toll Like Receptor 9 (TLR9) stimulation by CpG. Indeed, TLR9 activation was associated with an increased expression of Tyrosine Hydroxylase – an enzyme converting L-Tyrosine to L-DOPA – as well as Beta adrenergic receptors. These findings were supported through the use of our ELISA kits enabling detection of Dopamine and Noradrenaline (# BA-E-5500). Finally, the authors highlighted the suppressive function of catecholamines via an autocrine/paracrine mechanism. Tryptophan metabolism is associated with BMI and adipose tissue mass and linked to metabolic disease in pediatric obesityLischka et al. , Nutrients, 2022In this prospective study, the objective was to evaluate the impact of pediatric obesity on the Tryptophan catabolism through both the Kynurenine and Serotonin pathways. Tryptophan and Kynurenine levels were measured in plasma samples using ImmuSmol ELISA... --- - Published: 2022-02-07 - Modified: 2025-06-10 - URL: https://www.immusmol.com/123-news-sera-or-plasma-samples-it-matters-for-amino-acid-levels-html/ Using our ELISA kits, we quantified several amino acids in matched plasma-serum samples. The results highlights the importance of the sample matrix for the quantification of amino acids, which must be considered for clinical investigations. While amino acids play essential roles in several metabolic pathways, the quantification of free amino acids in biological fluids has provided important information in many pathophysiological contexts, including metabolic deficiencies, liver (1) and renal (2) failures, cancer (3), diabetes (4), muscle dysfunction, and Alzheimer’s disease (5). Nevertheless, because amino acid quantification in serum or plasma and its translation at the clinical stage, particularly, can be challenging due to the complexities of these matrices, it’s critical to master the assay robustness as well as to consider the importance of the nature of the sample matrix. Taking advantage of our robust and easy-to-implement ELISA kits, we quantified several amino acids, namely L-Arginine (#IS-I-0400), L-Glutamine (#IS-I-1100), L-Lysine (#IS-I-1400), L-Phenylalanine (#IS-I-1700), L-Serine (#IS-I-1200) and L-Tryptophan (#BA-E-2700) in matched plasma-serum samples obtained from eight healthy donors. Interestingly, while for two amino acids – Glutamine and Tryptophan – levels are similar in both matrices, Arginine, Lysine and Serine have lower levels in plasma than in serum. Conversely, Phenylalanine is higher in plasma than in serum. Altogether, this dataset highlights the importance of the sample matrix for the quantification of amino acids and derivatives, which must be considered for clinical investigations(1) https://doi. org/10. 1097/00075197-199901000-00009(2) https://doi. org/10. 1016/s0272-6386(12)80371-4(3) https://doi. org/10. 1371/journal. pone. 0024143(4) https://doi. org/10. 1007/s12603-018-1108-3(5) https://doi. org/10. 1093/ajcn/80. 2. 483 --- - Published: 2021-12-22 - Modified: 2021-12-22 - URL: https://www.immusmol.com/122-news-our-products-increasingly-referenced-in-2021-html/ Discover the scientific publications written in 2021 that cite Immusmol products! Antibodies, STAINperfect and ELISA kits were used and referenced in these recent articles that we have selected. For more informations check out our product page! Our antibodies, STAINperfect and ELISA kits were used and cited in many scientific publications in 2021, review a short selection! Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Can Extensively Differentiate to Tyrosine-Hydroxylase-Expressing Dopamine-Secreting Neurons, Cells IS1005 Dopamine and STAINperfect Improvement of loperamide-induced slow transit constipation by Bifidobacterium bifidum G9-1 is mediated by the correction of butyrate production and neurotransmitter profile due to improvement in dysbiosis, PLoS One BA-E-5300 Dopamine ELISA kit and BA-E5900 Serotonin ELISA kit Alkyne-Tagged Dopamines as Versatile Analogue Probes for Dopaminergic System Analysis, Analytical Chemistry IS1005 Dopamine and STAINperfect Paliperidone Reversion of Maternal Immune Activation-Induced Changes on Brain Serotonin and Kynurenine Pathways, Front Pharmacol. ISE-2227 Kynurenine/Tryptophan ELISA pack Deep learning model enables the discovery of a novel immunotherapeutic agent regulating the kynurenine pathway, Oncoimmunology BA-E-2200 Kynurenine ELISA kit and BA-E-2700 Tryptophan ELISA kit Quantification of normetanephrine in canine urine using ELISA: evaluation of factors affecting results, J Vet Diagn Invest BA-E-8600 Metanephrine-Normetanephrine ELISA kit Methoxphenidine (MXP) induced abnormalities: Addictive and schizophrenia-related behaviours based on imbalance of neurochemicals in the brain, British Journal of Pharmacology BA-E-2400 Glutamate ELISA Circulating concentrations of citrulline, neopterin, kynurenine, and tryptophan during chemoradiation in patients with cervical carcinoma, Pteridines BA-E-2200 Kynurenine ELISA kit and BA-E-2700 Tryptophan ELISA kit Early-life experiences altered the maturation of the lateral habenula in mouse models, resulting in behavioural disorders in adulthood, J Psychiatry Neurosci IS1006 GABA and STAINperfect Mood Disorder in Systemic Lupus Erythematosus Induced by Antiribosomal P Protein Antibodies Associated with Decreased Serum and Brain Tryptophan, J Immunol. BA-E-2700... --- - Published: 2021-09-08 - Modified: 2025-06-10 - URL: https://www.immusmol.com/118-news-l-serine-quantification-by-elisa-now-possible-html/ We developed and validated a newSerine ELISA kit (#IS-I-1200) which allows for L-Ser quantitation in biological samples including plasma, sera as well as cell culture supernatants. The assay requires a low sample volume of 10μL and is characterized by a 2.4µM sensitivity. L-Serine (L-Ser) is a non-essential amino acid which becomes conditionally essential – in certain circumstances – particularly when it cannot be synthesized in a sufficient amount to meet the cellular demands. L-Ser may be derived from different sources including dietary intake, the glycolytic intermediate 3-phosphoglycerate, glycine as well as protein and phospholipid degradation. It’s worth noting that enzymes involved in L-Ser biosynthesis are upregulated in highly proliferating cells, including cancer cells, to limit L-Ser over-consumption. Besides its essential role in cell proliferation, L-Ser is important for brain development and functions which are especially sustained by i) altered L-Ser levels in psychiatric disorders and ii) occurrence of severe neurological abnormalities in patients with defects in L-Ser biosynthesis. Given its roles in such critical functions, L-Ser quantification in biological samples is critical. We thus developed and validated a novel Serine ELISA kit (#IS-I-1200) which allows for L-Ser quantitation in biological samples including plasma, sera as well as cell culture supernatants. The assay requires a low sample volume of 10μL and is characterized by a 2. 4µM sensitivity. Shop L-Serine ELISA kit --- - Published: 2021-05-19 - Modified: 2025-06-10 - URL: https://www.immusmol.com/116-news-elisa-based-quantification-of-glutamine-cancer-cell-lines-html/ Glutamine metabolism is an attractive therapeutic path in immuno-oncology. Glutamine level should rely mainly on Glutamine quantification, which can now be addressed by ELISA! L-Glutamine (Gln) - a conditionally essential amino acid - is the most abundant free amino acid in human blood. As a source of carbon and nitrogen, Gln supplies many intermediates required for multiple metabolic functions including, among others, purine, pyrimidine, and glutathione synthesis pathways. In addition, one of the important functions of Gln - once deaminated into Glutamate by Glutaminase (Gls1 & Gls2) - is to fuel the citric acid cycle (TCA), which represents a major energy-producing process, especially for highly proliferating cells e. g. T lymphocytes and cancer cells. Hence, because of the cohabitation of both cell types within tumors and the high rate of tumoral glutaminolysis, immune cells are likely to be often deprived of Gln, a condition which can severely limit their functions. Given its pleiotropic role, targeting Gln metabolism thus represents an attractive druggable therapeutic avenue in immuno-oncology. For instance, Gls1 can be directly targeted through Glutaminase inhibitors such as CB-839 (under clinical development in various type of cancers). Overall, assessing novel therapeutic molecules aiming at restoring Gln level should rely, mainly, on Gln quantification, which can now be addressed by ELISA! Tumor cell lines from both murine and human origins degrade Glutamine to support their high proliferating rate in a Gls1 dependent manner. A. Mouse 4T1 breast and CT26 colorectal cancer cell lines were treated with increasing concentrations of Gls1 inhibitor (CB-839) for 48 hours and at the end of the treatment period, cell culture supernatants were collected for Glutamine quantification using our ELISA kit... --- - Published: 2021-03-30 - Modified: 2025-06-10 - URL: https://www.immusmol.com/115-news-arginine-level-by-elisa-as-a-surrogate-for-arginase-activity-html/ New therapeutic options in immuno-oncology consist in manipulating metabolic pathways. Whatever the mechanism of action of drug candidates Arginine remains a suitable surrogate biomarker of Arginase activity. Its quantification can be approached by ELISA! Arginine metabolism is involved in many cell functions and plays an important role among others in the regulation of immune cell reactivity and carcinogenesis. For instance, while Arginine is essential for T cell activity, TAMs and MDSCs – through the expression and activity of Arginase – favor its degradation thereby participating in immunosuppression. Novel therapeutic options in immuno-oncology consist in manipulating such a metabolic pathway to relieve the function of immunosuppressive macrophages. For instance, Arginase 1 can be targeted directly through the use of Arginase inhibitors (eg. INCB-001158) or indirectly through the modulation of specific signaling pathways (eg. PI3K). Finally, whatever the mechanism of action of drug candidates, Arginine remains a suitable surrogate biomarker of Arginase activity and its quantification can now be approached by ELISA! Shop Arginine ELISA kit --- - Published: 2021-02-25 - Modified: 2021-02-25 - URL: https://www.immusmol.com/114-news-neurotransmitter-imaging-validated-antibodies-cited-in-many-recent-publications-html/ We have set up and validated a series of antibodies targeting key neurotransmitters, including among others dopamine, serotonin, glutamate, noradrenaline. Besides antibodies, and for appropriate biological sample preparation, we developed an immunostaining kit that allows for immunofluorescence staining of various types of biological materials, as illustrated in these recent publications. Serving as chemical messengers, neurotransmitters play a key role in several physiological processes. Neurotransmitter imbalance can be specifically associated with diseases, e. g. dopamine production default in Parkinson’s disease or altered level of serotonin in depression. Also, different drug development programs have been conducted in order to alleviate such an imbalance and ultimately even stop the disease progression. Tools allowing for the determination of neurotransmitter content and localization might be valuable to delineate more in depth neuronal biology in both physiological and pathological situations, as well as to investigate mechanisms of action of novel disease-targeting pharmacological approaches. For this purpose, we have set up and validated a series of antibodies targeting key neurotransmitters, including among others dopamine, serotonin, glutamate, noradrenaline. Besides antibodies, and for appropriate biological sample preparation, we developed an immunostaining kit that allows for immunofluorescence staining of varied types of biological materials, as illustrated in some recent publications. Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids Smits et al. , Cell and Tissue Research, 2020. Dopamine (#IS1005), Serotonin (#IS040), L-Glutamine (#IS1060), GABA (#IS039). hiPS Cell-Derived Neurons for High-Throughput Screening Traub and Heilker, Methods in Molecular Biology, 2019. GABA (#IS039), L-Glutamate (#IS1001). Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson’s disease Nickels et al. , Stem Cell Research, 2020. Dopamine (#IS1005). --- - Published: 2021-01-07 - Modified: 2021-01-07 - URL: https://www.immusmol.com/111-news-our-products-increasingly-cited-html/ Our products were hilighted in 2020 in these scientific publication. Antibodies, STAINperfect and ELISA kits were used and referenced. Our antibodies, STAINperfect and ELISA kits were used and cited many times in scientific publications in 2020, review a short selection! Serum kynurenine levels are a novel biomarker to predict the prognosis of patients with hepatocellular carcinoma, PLos One. BA-E-2200 Kynurenine ELISA kit Diagnostic accuracy of plasma kynurenine/tryptophan ratio, measured by enzyme-linked immunosorbent assay, for pulmonary tuberculosis, Int J Infect. Dis. ISE-2227 Kynurenine/Tryptophan ELISA pack Gut microbiota-induced changes in b-hydroxybutyrate metabolism are linked to altered sociability and depression in alcohol use disorder, Cell Rep. BA-E-2400 Glutamate and BA-E-2500 GABA ELISA kits Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids, Cell Tissue Res. SP-A-1000 STAINperfect immunostaning kit IS1005 Dopamine / IS040 Serotonin / IS039 GABA antibodies Apple polyphenols induce browning of white adipose tissue, The Journal of Nutritional Biochemistry BA-E-5200 Norepinephrine ELISA kit IDO targeting in sarcoma: biological and clinical implications, Front Immunol. ISE-2227 Kynurenine/Tryptophan ELISA pack Clioquinol inhibits dopamine-β-hydroxylase secretion and noradrenaline synthesis by affecting the redox status of ATOX1 and copper transport in human neuroblastoma SH-SY5Y cells, Archives of Toxicology BA-E-5200 Norepinephrine ELISA kit Prognostic value of indoleamine 2,3 dioxygenase in patients with higher-risk myelodysplastic syndromes treated with azacytidine, British Journal of Haematology ISE-2227 Kynurenine/Tryptophan ELISA pack Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis, Cancers BA-E-2200 Kynurenine ELISA kit Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson’s disease, Stem Cell Research BA-E-5300 Dopamine ELISA kit --- - Published: 2020-09-23 - Modified: 2025-06-10 - URL: https://www.immusmol.com/108-news-kynurenine-tryptophan-as-surrogate-markers-for-innovative-ido-modulators-screening-html/ Novel therapeutic options in immuno-oncology consist in manipulating – directly or indirectly - metabolic pathways such as the one of IDO to relieve the immunosupressive functions of M2 macrophages. As to investigate innovative direct or indirect modulators of IDO activity, Kynurenine and Tryptophan represent valuable biomarkers to be measured and can easily be adressed through ELISA kits which thus offer screening capacities. Macrophages represent a wide group of functionally-different subpopulations involved in several immunological functions. In contrast to M1 macrophages which favor a pro-inflammatory response, M2 macrophages trigger inflammation resolution and suppress T cell activation via several mechanisms including release of anti-inflammatory cytokines, immune checkpoint engagement, and metabolic activities such as indoleamine 2,3-dioxygenase (IDO), which concomitantly promotes Tryptophan degradation and Kynurenines production. Novel therapeutic options in immuno-oncology consist in manipulating – directly or indirectly – such a metabolic pathway to relieve the immunosupressive functions of M2 macrophages. Indeed, IDO can be modulated directly through conventional pharmacological inhibition (eg. Epacadostat) or indirectly through modulation of specific signaling pathways (eg. PI3K). As to investigate innovative direct or indirect modulators of IDO activity, Kynurenine and Tryptophan represent valuable biomarkers to be measured and can easily be adressed through ELISA kits which thus offer screening capacities. IDO activity of M2 polarized macrophages is decreased by its pharmacological blockade but also through PI3K signaling pathway inhibition. M2-macrophages were treated during the polarization with increasing concentrations of Epacadostat – as a prototypical IDO inhibitor – or LY294002 – a reference PI3K inhibitor. ELISA-based quantification of L-Tryptophan and L-Kynurenine levels in the supernatants (using BA-E-2700 and BA-E-2200 kits, respectively) revealed a dose-dependent inhibition of activated IDO as highlighted by the increase and decrease of Tryptophan and Kynurenine, respectively. Kynurenine and Tryptophan ELISA pack --- - Published: 2020-06-22 - Modified: 2025-06-10 - URL: https://www.immusmol.com/107-news-newly-released-elisa-kit-for-arginine-arg-html/ Arginine (ARG) is a basic non-essential amino acid well known to participate in physiological functions such as i) vascular tone homeostasis as contributing to the production of nitric oxide (NO) and ii) immune response control, through NO synthase (NOS) and Arginase enzymes, respectively. Our new validated IS-I-0400 ELISA kit allows for the determination of ARG in serum and plasma samples of a volume as low as 20μL and with a sensitivity of 2.1µM. Arginine (ARG) is a basic non-essential amino acid well known to participate in physiological functions such as i) vascular tone homeostasis as contributing to the production of nitric oxide (NO) and ii) immune response control, through NO synthase (NOS) and Arginase enzymes, respectively. A dysregulation in ARG catabolism has been already linked to tumor progression and immune escape. Indeed, overexpression of Arginase in tumor and immunosuppressive cells (eg. Myeloid Derived Suppressor Cells) contributes to an excessive use of ARG thereby limiting its availability for effector immune cells. Arginase represents therefore an attractive therapeutic target to restore anti-tumor immunity and inhibitors (eg. INCB001158) are currently under clinical development in several cancer indications. ARG measurement in biological samples such as plasma or serum thus represents a suitable surrogate marker for novel Arginase inhibitors. Our new validated IS-I-0400 ELISA kit allows for the determination of ARG in serum and plasma samples of a volume as low as 20μL and with a sensitivity of 2. 1µM. (A) ARG was quantified in human plasma samples from 19 healthy donors and 46 cancer patients from several histotypes using IS-I-0400 Arginine ELISA kit. As depicted, ARG level was lower in cancer patients than in healthy subjects thus arguing for an exagerated Arginase activity in cancer patients. (B) Microdialysis was performed in MCA205-sarcoma tumor-bearing mice in both tumor and non-tumor regions and collected microdialysates were subjected to ARG quantification using IS-I-0400 ELISA kit. As expected, Arginine level was lower in the tumor compartment when compared to the subcutaneous... --- - Published: 2020-05-14 - Modified: 2025-06-10 - URL: https://www.immusmol.com/106-news-newly-released-elisa-pack-for-kynurenic-quinolinic-acids-html/ Through the degradation of L-Tryptophan, the Kynurenine pathway (KP) generates a series of catabolites collectively known as Kynurenines, which can exert immunomodulatory and/or neuroactive properties. Known to respectively harbor neuroprotective and neurotoxic functions, Kynurenic (KYNA) and Quinolinic (QA) acids are found to be dysregulated in several neuroinflammatory disorders including Parkinson and Alzheimer disease but also Amyotrophic Lateral Sclerosis and Multiple Sclerosis. We developed novel ELISA detection kits to monitor the imbalance between KYNA and QA levels in neurological diseases and evaluate the ability of novel KMO inhibitors to restore equilibrium within the KP and mitigate neurodegeneration. Through the degradation of L-Tryptophan, the Kynurenine pathway (KP) generates a series of catabolites collectively known as Kynurenines, which can exert immunomodulatory and/or neuroactive properties. Known to respectively harbor neuroprotective and neurotoxic functions, Kynurenic (KYNA) and Quinolinic (QA) acids are found to be dysregulated in several neuroinflammatory disorders including Parkinson and Alzheimer disease but also Amyotrophic Lateral Sclerosis and Multiple Sclerosis. Manipulating the Kynurenine Monoamine Oxygenase (KMO) – an enzyme at the crossroads of KYNA and QA - has been proposed as a valuable therapeutic approach to shift Kynurenine degradation towards the formation of KYNA. We developed novel ELISA detection kits to monitor the imbalance between KYNA and QA levels in neurological diseases and evaluate the ability of novel KMO inhibitors to restore equilibrium within the KP and mitigate neurodegeneration. Measurement of plasma levels of both KYNA and QA in mice treated with KMO inhibitors. Mice were treated with two selective KMO inhibitors – Ro-618048 & UPF648 – at two different doses each. Plasma samples were collected before treatment and at 1h30 and 6h post-treatment. KYNA and QA levels were then quantified by mean of ELISA (IS-I-0200 and IS-I-0100). As depicted above, blockade of KMO time- and dose-dependently favors the degradation of Kynurenine into KYNA. Interestingly, no major effect is observed on QA level thus suggesting compensatory mechanism to maintain stable circulating QA level. More about the ELISA pack for Kynurenic / Quinolinic Acids --- - Published: 2020-04-23 - Modified: 2025-06-10 - URL: https://www.immusmol.com/105-news-homoarginine-harg-elisa-kit-out-now-html/ HomoArginine (hArg) is a basic non-essential amino acid that exerts beneficial effects on vascular homeostasis, more likely through the increase of nitric oxide (NO) that can be explained through two mechanisms since hArg i) serves as a precursor of NO and ii) favors the elevation of L-Arg - main substrate of NO synthase - by inhibiting the enzyme Arginase. Our IS-I-0500 ELISA kit allows for the determination of hArg in serum and plasma samples in a minimal sample volume of 20μL and with a sensitivity of 125nM. HomoArginine (hArg) is a basic non-essential amino acid that exerts beneficial effects on vascular homeostasis, more likely through the increase of nitric oxide (NO) that can be explained through two mechanisms since hArg i) serves as a precursor of NO and ii) favors the elevation of L-Arg – main substrate of NO synthase – by inhibiting the enzyme Arginase. Our IS-I-0500 ELISA kit allows for the determination of hArg in serum and plasma samples in a minimal sample volume of 20μL and with a sensitivity of 125nM. (A) Typical standard curve obtained with the hArg ELISA kit where the optical density is inversely correlated with hArg levels within a linear range of 0. 32 – 12. 5μM. (B) hArg was quantified in human serum samples from 40 healthy subjects using IS-I-0500 ELISA kit or by liquid chromatography–mass spectrometry (LC/MS). Correlation study showed R2=0. 9642, thereby confirming the accuracy of the immunoassay. More about the Homoarginine ELISA kit --- - Published: 2020-03-12 - Modified: 2025-06-10 - URL: https://www.immusmol.com/101-news-new-elisa-kit-out-now-for-kynurenic-acid-html/ New ELISA Kit out now for Kynurenic Acid! Kynurenic acid (KYNA) is a downstream metabolite produced along the Kynurenine Pathway well-known to possess several neuromodulatory functions, as well as immuno-modulatory properties. Measurement of KYNA in biological samples has been presented as a possible biomarker in several diseases including neurological or psychiatric disorders. The Kynurenic Acid ELISA kit is optimized for the quantitation of Kynurenic Acid (KYNA) within serum samples. This easy-to-use competitive assay is well-suited for both small and large series of samples. Working with a 50µL sample volume, this assay enables pre-clinical and clinical sample testings. 96-w plate formatLow volume samplesSensitive, easy-to-implementCross-validated with LC/MS Assay specifications Format96-well kitSpecies reactivityAny speciesSamplesSerumSample volume50μLSensitivity0. 53 ng/mLAssay range1. 40 - 74 ng/mLAssay timeSample derivatization 90min ; ELISA: Overnight More about the Kynurenic Acid ELISA kit --- - Published: 2020-01-28 - Modified: 2025-06-10 - URL: https://www.immusmol.com/100-blog-reveal-dopamine-in-your-samples-using-our-dedicated-tools-html/ Reveal Dopamine in your samples using our dedicated tools Levels of dopamine highlighted by ELISA in the afferent and efferent dopaminergic systemsFigure 1: Mouse brain tissue levels of dopamine quantified and shown in different areas using a specific dopamine ELISA kit (BA-E-5300). As expected, high levels of dopamine were detected in the afferent and efferent dopaminergic systems, i. e. putamen, midbrain, and olfactory bulbs. More about the Dopamine ELISA kit Dopaminergic nigral neurons identified by IS1005 Dopamine antibody that colocalizes with TH stainingFigure 2: Dopaminergic nigral neurons in coronal rat brain sections revealed by anti-dopamine (DA, rabbit polyclonal antibody #IS1005) and Tyrosine Hydroxylase (TH, #MAB5280, reference catecholaminergic neuron immunostaining). As highlighted in the overlay, DA immunoreactivity localizes with TH staining in the Substantia nigra pars compacta, thus showing that our antibody against the DA neurotransmitter - used with the STAINperfect immunostaining kit A – is a validated tool to directly highlight DAergic system networks. More about our dopamine antibody --- - Published: 2019-12-20 - Modified: 2025-06-10 - URL: https://www.immusmol.com/98-blog-take-the-opportunity-of-a-special-offer-to-try-our-dopamine-ab-html/ Take the opportunity of a special offer to try our Dopamine Ab Dopaminergic neurons of the Substantia Nigra pars compacta (SNc) in coronal rat brain sections revealed by anti-dopamine (DA, rabbit polyclonal antibody #IS1005) and Tyrosine Hydroxylase (TH, #MAB5280, reference catecholaminergic neuron immunostaining). As highlighted in the overlay, DA immunoreactivity well correlates with TH immunoreactivity in the SNc, thus showing that our antibody against the DA neurotransmitter – used with the STAINperfect immunostaining kit A – is a validated tool to directly highlight DAergic systems rather than through biosynthesis enzyme immunostaining, expressed in all catecholaminergic cell populations. --- - Published: 2019-10-31 - Modified: 2025-06-10 - URL: https://www.immusmol.com/93-blog-quinolinic-acid-elisa-kit-now-out-html/ Quinolinic Acid ELISA kit: NOW OUT! 96-w plate format / Low volume samples / Sensitive, easy-to-implement / Cross-validated with LC/MS The Quinolinic acid (QUIN or QA) ELISA kit is an easy-to-use assay tailored for the quantification of QA across large series of samples. Optimized for the analysis of serum samples, the QA ELISA features a lower limit of detection at (6ng/mL) and a minimal sample volume (25μL), thus allowing human ancillary studies. 96-w plate formatLow volume samplesSensitive, easy-to-implementCross-validated with LC/MSAssay specifications Format96-well kitSpecies reactivityAny speciesSamplesSerumSample volume25μLSensitivity< 6ng/mLAssay range25 - 2000 ng/mLAssay timeSample preparation: 2h ELISA: OvernightScientific backgroundQuinolinic acid (QA) is a metabolite produced along the Kynurenine Pathway, which converts the aminoacid Tryptophan to NAD+, a co-factor of many enzymatic reactions. It has been described to share several neurotoxic functions particularly through the activation of the N-Methyl-D-Aspartate receptor. Its production occurring in myeloid cells (macrophages, microglia, etc. ) is mainly driven by inflammatory stress and is therefore suspected to play a key role in neuroinflammatory disorders such as Alzheimer and Parkinson diseases but also Multiple Sclerosis, Amyotrophic Lateral Sclerosis. Hence, while QA has been proposed as a biomarker in these indications, it might certainly warrant further investigation to serve as a surrogate in other “inflammation” related diseases such as cancer, metabolic disorders, etc. More about the Quinolinic Acid ELISA kit --- - Published: 2019-09-10 - Modified: 2025-06-10 - URL: https://www.immusmol.com/90-blog-versatile-quantification-of-kynurenine-tryptophan-levels-by-elisa-html/ Kynurenine and tryptophan as surrogate immune suppression tumor biomarkers While being neglected for decades, tumor immune escape is now considered as a new paradigm that promotes tumor growth and evasion. Besides the prototypical PD1 / PDL1 axis, several mechanisms have been identified as important actors in immune editing process. Indoleamine 2,3 dioxygenase (IDO1), a first rate-limiting enzyme of the Kynurenine pathway, has been described to favor tolerance and immune escape through the production of a series of metabolites, including L-Kynurenine. In this context, our ISE-2227 Kynurenine/tryptophan ELISA pack represents a powerfull tool to adress these metabolites. Versatile Kynurenine/tryptophan level measurement and characterization of IDO1 inhibition. A. Microdialysates were collected from intratumoral vs. non-tumoral regions of tumor-bearing mice inoculated with the indicated tumor cell lines, for the determination of kynurenine to tryptophan ratio (KTR). As illutsrated, KTR is higher in tumor regions when compared to their respective non-tumor regions thus highlighting the participation of this pathway in tumor progression and eventually in immunotherapy resistance. Interestingly, MCA205-tumor bearing mice treated with an IDO inhibitor (Navoximod) displayed a significant decrease in KTR within the tumor. B. Mature human dendritic cells (mDCS) were cultured together with HLA-mismatched CD4+ T cells (mixed lymphocyte reaction context) and exposed for 72 hours with increasing concentrations of a reference IDO1 inhibitor. Supernatants were then collected for kynurenine and tryptophan content measurement by mean of ELISA (ISE-2227 Kynurenine/tryptophan ELISA pack). Kynurenine content (through KTR) is dose-dependently decreased by IDO inhibition. Assessment of plasmatic kynurenine/tryptophan levels in cancer patients. A cohort of patients with various types of sarcomas were... --- - Published: 2019-06-13 - Modified: 2025-06-10 - URL: https://www.immusmol.com/87-blog-validated-monoclonal-antibody-to-assess-gaba-by-immunofluorescence-if-and-immunohistochemistry-ihc-html/ Validated monoclonal anti-GABA antibody to evaluate GABAergic system network/function by immunofluorescence Gamma-AminoButyric Acid (GABA) is the major inhibitory neurotransmitter in the developmentally mature vertebrate central nervous system, which binds GABAA and GABAB receptors thereby causing hyperpolarization and neuronal activity inhibition. GABA system/function alterations are known to be associated with many psychiatric and neurological disorders, e. g. anxiety, depression, schizophrenia, sleep disorders, insomnia... The 7F5. 2B4. 1B4 monoclonal antibody has been developed and validated to directly react with and label GABA, thereby making it a suitable tool to evaluate GABAergic system networks / function by immunofluorescence (IF) and immunohistochemistry (IHC), on varied types of biological materials. GABAergic neuronal network in a mature rat cortical culture revealed through GABA immunoreactivity detection using either our mouse monoclonal GABA antibody (#IS039) in green or rabbit polyclonal GABA antibody (#IS1006) in red, with the STAINperfect immunostaining kit A. GABAergic network is identically revealed by both antibodies (yellow on the overlay) which evidence the cortical GABAergic neurons as well as their rich and dense neuritic extensions. GABAergic network and glutamatergic cell populations in a mature rat cortical culture revealed by GABA (mouse monoclonal antibody #IS039) and L-glutamate (rabbit polyclonal antibody #IS1001) immunoreactivity. As expected, our antibodies, appropriately used with the STAINperfect immunostaining kit A, highlight the rich cortical GABAergic system (cell bodies and branches – displaying a punctiform staining) as well as the glutamate-positive cell population. While GABA neurons are also glutamate-positive (some are pointed by the arrows), arrowheads point glutamate-positive GABA-negative cells, which can be either astrocytes or glutamatergic neurons. Image field micrographs of mature (12... --- - Published: 2019-05-10 - Modified: 2025-06-10 - URL: https://www.immusmol.com/86-blog-validated-antibody-to-assess-l-kynurenine-by-ihc-html/ Validated antibody to assess L-Kynurenine by IHC The 3D4-F2 monoclonal antibody has been developped to react with L-Kynurenine, the first stable metabolite of the Kynurenine Pathway which is known to be induced upon inflammatory situations including cancer, neurodegerenative diseases, infections, etc. This antibody is a suitable immunohistochemistry (IHC) / immunohistofluorescence (IHF) dedicated tool to evaluate Kynurenine levels in varied types of samples. (Top image) Immunohistochemical analysis reveals accumulation of L-Kynurenine in tumor cells of human colorectal cancer tissue. Paraffin-embedded tissue section was subjected to antigen retrieval, and incubation with primary IS003 anti-KYN monoclonal antibody. DAB imunostainng revelation was performed using DiscoveryUltra™ autostaining platform. Image (x40 magnification) was acquired using Polaris Vectra (Perkin Elmer) automated slide scanner. Our L-Kynurenineantibodies were also cited in the liitterature for other applications ... See publication Quintana et al. 2019 - See publication Mehra et al. , 2017 --- - Published: 2019-04-09 - Modified: 2025-06-10 - URL: https://www.immusmol.com/84-blog-kynurenine-levels-measured-by-elisa-html/ Kynurenine levels measured by ELISA - Special offer Effect of IDO1 inhibition on kynurenine levels measured in cell culture supernatants or in mouse plasma samples. A. Human sarcoma tumor cell line was cultured and stimulated with human IFNgamma for 48 hours in the presence of increasing concentrations of reference IDO1 inhibitors - either Epacadostat or Navoximod. Supernatants were then collected for kynurenine content measurement by mean of ELISA (BA-E-2200 Kynurenine ELISA kit). IFNgamma-induced kynurenine production is dose dependently reversed by both IDO1 inhibitors with a more potent inhibitory activity observed for Epacadostat B. C57BL/6 mice were exposed to LPS (5mg/kg) with and without Navoximod IDO1 inhibitor at 100mg/kg or 200mg/kg. Mice were bleeded on Days 1, 3 and 5 and kynurenine was measured in plasma by ELISA (BA-E-2200 Kynurenine ELISA kit). IDO1 inhibition using Navoximod limits both basal and LPS-stimulated plasmatic level of kynurenine. More about the L-Kynurenine ELISA kit --- - Published: 2019-02-26 - Modified: 2025-06-10 - URL: https://www.immusmol.com/82-blog-effect-of-ido1-inhibition-on-kynurenine-levels-measured-by-elisa-html/ Effect of IDO1 inhibition on Kynurenine levels measured by ELISA Effect of IDO1 inhibition on kynurenine levels measured in cell culture supernatants or in mouse plasma samples. A. Human sarcoma tumor cell line was cultured and stimulated with human IFNgamma for 48 hours in the presence of increasing concentrations of reference IDO1 inhibitors - either Epacadostat or Navoximod. Supernatants were then collected for kynurenine content measurement by mean of ELISA (BA-E-2200 Kynurenine ELISA kit). IFNgamma-induced Kynurenine production is dose dependently reversed by both IDO1 inhibitors with a more potent inhibitory activity observed for Epacadostat B. C57BL/6 mice were exposed to LPS (5mg/kg) with and without Navoximod IDO1 inhibitor at 100mg/kg or 200mg/kg. Mice were bleeded on Days 1, 3 and 5 and kynurenine was measured in plasma by ELISA (BA-E-2200 Kynurenine ELISA kit). IDO1 inhibition using Navoximod limits both basal and LPS-stimulated plasmatic level of Kynurenine. Try our Kynurenine ELISA kit ! --- - Published: 2019-01-22 - Modified: 2025-06-10 - URL: https://www.immusmol.com/quantitative-analysis-of-neurite-outgrowth-using-is1006-gaba-antibody/ Quantitative analysis of neurite outgrowth using IS1006 GABA antibody Glutamate toxicity on GABAergic network of rat cortical primary neurons. 10 DIV-old rat cortical cultures were exposed for 96h to increasing glutamate concentrations in the presence & absence of MK801 (NMDA-R antagonist). GABAergic neuronal network was revealed by GABA immunostaining using ImmuSmol IS1006 rabbit GABA antibody and STAINperfect kit A. Representative images are shown in (A). Images were segmented and analyzed to quantitfy GABAergic neurite outgrowth as endpoint (B). Glutamate decreases the GABAergic neurite length in dose-dependent manner, an effect reversed by the NMDA-R antagonist. Try our GABA antibody --- - Published: 2017-09-20 - Modified: 2025-06-12 - URL: https://www.immusmol.com/70-blog-immusmol-highlighted-in-two-recent-scientific-publications-html/ ImmuSmol's antibodies targeting small molecules, such as the neurotoxic amino-acid BMAA, were used and highlighted in two recent publications. ImmuSmol's antibodies targeting small molecules, such as the neurotoxic amino-acid BMAA, were used and highlighted in two recent publications. To learn more about our small molecule antibodies, visit our product page and feel free to contact us! --- - Published: 2017-05-11 - Modified: 2017-05-11 - URL: https://www.immusmol.com/69-blog-meet-us-at-the-neurofrance-2017-in-bordeaux-html/ Meet us at the NEUROFRANCE 2017 in Bordeaux Visit our booth #34 at NeuroFrance 2017! and learn about our ELISA kits and antibody offers ImmuSmol will be present at NeuroFrance 2017 Our team will be glad to welcome you at our booth (#34) and have a chat about our range of products & services that could serve your projects! --- - Published: 2016-05-24 - Modified: 2025-06-12 - URL: https://www.immusmol.com/66-blog-new-antibody-for-noradrenaline-now-available-using-stainperfect-immunostaining-kit-html/ New antibody for Noradrenaline now available using STAINperfect immunostaining kit Using STAINperfect immunostaining kit A, Noradrenaline (norepinephrine) was specificaly detected in the CNS of embryonic mouse (E13. 5). Noradrenergic soma and fibers were detected in the pons (left image), while in the spinal cord only fibers were revealed (right image). Staining was obtained following the protocol optimized for whole mount samples and using polyclonal antibody targeting L-Noradrenaline (ImmuSmol, ref: IS1042). Fluorescent conjugated secondary antibody was used and images obtained by confocal imaging. --- - Published: 2016-05-03 - Modified: 2025-06-12 - URL: https://www.immusmol.com/65-blog-challenge-serotonin-and-its-precursor-l-tryptophan-using-stainperfect-immunostaining-kit-html/ Challenge Serotonin and its precursor L-Tryptophan using STAINperfect immunostaining kit Using STAINperfect immunostaining kit A, Tryptophan was detected within the hindbrain of embryonic mouse E15. 5 following the protocol for whole mount samples (image on left, red). Serotonin, a tryptophan metabolite, was detected in the raphe nucleus from adult mice on floating sections prepared with the STAINperfect immunostaining kit A. Stainings were performed using anti-Tryptophan Mouse monoclonal Ab (IS011) and Serotonin Rabbit polyclonal Ab (IS1007). Fluorescent conjugated secondary antibodies were used and images acquired by confocal imaging. --- - Published: 2016-04-12 - Modified: 2025-06-12 - URL: https://www.immusmol.com/64-blog-get-access-to-the-dopamine-and-serotonin-crosstalk-using-stainperfect-immunostaining-kit-html/ Get access to the Dopamine and Serotonin crosstalk using STAINperfect immunostaining kit Using STAINperfect immunostaining kit A, Dopamine and Serotonin are detected either into the CNS of embryonic mouse E13. 5 following the protocol for whole mount samples (upper images) or in mouse primary neuronal culture (midbrain) following the protocol for cell culture (lower images) and using Dopamine Rabbit pAb (IS1005) and Serotonin Goat pAb (IS0135). Fluorescent conjugated secondary antibodies were used and images acquired by confocal imaging. --- - Published: 2016-03-24 - Modified: 2025-06-12 - URL: https://www.immusmol.com/63-blog-launch-of-explicyte-immuno-oncology-html/ ImmuSmol is launching Explicyte Immuno-Oncology: a brand-new range of preclinical services in the field of cancer immunotherapy. ImmuSmol is launching today a range of preclinical services in the field of cancer immunotherapy under the brand Explicyte Immuno-Oncology. Explicyte Immuno-Oncology currently offers to test innovative cancer immunotherapies in vivo, using syngeneic mouse tumor models treated with immune checkpoint inhibitors (eg. anti-CTLA-4 and anti-PD1/PD-L1 antibodies). In addition, Explicyte is setting up an in vitro platform for the identification and optimization of novel immunomodulators. Equipped with high-content analysis technologies, the platform will focus on live phenotypic screening in co-cultures of immune and cancer cells, as well as molecular cell-based assays for the assessment of immune checkpoint inhibitors. www. explicyte. com/immuno-oncology/ --- - Published: 2016-03-22 - Modified: 2025-06-12 - URL: https://www.immusmol.com/62-blog-neurotransmitter-imaging-differential-organization-of-two-key-neurotransmitters-within-neurons-revealed-by-stainperfect-kit-html/ Neurotransmitter imaging: Differential organization of two key neurotransmitters within neurons revealed by STAINperfect kit Using STAINperfect immunostaining kit A, GABA and L-Glutamate were stained in mouse culture of primary cortical neurons. This staining highlights a differential organization of these two key neuromediators. Co-stainings were obtained following the protocol optimized for cell culture and using IS1006 rabbit polyclonal antibody against GABA and IS018 mouse monoclonal antibody targeting L-Glutamate. Fluorescent conjugated secondary antibodies were then used and images captured by confocal imaging. --- - Published: 2016-02-15 - Modified: 2025-06-12 - URL: https://www.immusmol.com/neurotransmitter-imaging-protocols-standard-procedure-versus-stainperfect-immunostaining-kit-html/ Why using the STAINperfect immunostaining kit ? We compared the standard immunostaining procedure to the optimized STAINperfect protocol for cell cullture staining. Primary mouse embryonic cortical neurons were stained according to standard prodecudure or using the STAINperfect immunostaining kit to reveal both GABA (rabbit polyclonal antibody IS1006 from ImmuSmol) and the neuronal marker MAP2 (from Abcam). --- - Published: 2015-11-17 - Modified: 2015-11-17 - URL: https://www.immusmol.com/ido-tdo-inhibitor-screening-cell-based-assay-l-kynurenine-elisa-html/ Our L-Kynurenine ELISA can be used to screen IDO/TDO inhibitors in cell lines. See our data with IDO inhibitor 1-Methyl-L-Tryptophan. ImmuSmol's L-Kynurenine ELISA kit BA-E-2200 can be used to screen IDO/TDO inhibitors in cell lines. Below an example with IDO inhibitor 1-Methyl-L-Tryptophan. Measurement of IDO inhibition by 1-Methyl-L-Tryptophan in cancer cell line. IDO+ CT26 colorectal cancer cell line was exposed to increasing concentrations of 1-Methyl-L-Tryptophan. Kynurenine levels were measured in 20µL cell culture supernatant using ImmuSmol's ELISA kit BA-E-2200. --- - Published: 2015-11-03 - Modified: 2015-11-03 - URL: https://www.immusmol.com/l-glutamate-antibody-staining-brain-crayfish-html/ L-Glutamate antibody highlights the presence of glutamatergic cells in a crayfish brain. Using STAINperfect immunostaining kit A, the anti-L-Glutamate antibody (IS1001) highlights the presence of glutamatergic cells into a crayfish brain. Staining was obtained following the protocol for whole mounts samples. Alexa Fluor® 488 conjugated secondary antibody was used and images obtained by confocal imaging at high magnification. >>> GET YOUR STAINperfect TRIAL PACK ! --- - Published: 2015-10-27 - Modified: 2015-10-27 - URL: https://www.immusmol.com/5-ht-serotonin-antibody-primary-cell-culture-rat-html/ Serotonin antibody combined with STAINperfect immunostaining kit highlights the presence of Serotonin (in green) in rat primary mesencephalic cells (in red, MAP2). Using STAINperfect immunostaining kit A, the anti-Serotonin rabbit polyclonal antibody (Ref: IS1007) highlights Serotonin presence in soma and neurons projections within primary rat mesencephalic cell culture. The staining was performed according to the optimized protocol for cell culture and was revealed using Alexa Fluor® 488-conjugated secondary antibody. MAP2 was simultaneously stained and revealed using Alexa Fluor® 555-conjugated secondary antibody. >>> GET YOUR STAINperfect TRIAL PACK ! --- - Published: 2015-10-20 - Modified: 2015-10-20 - URL: https://www.immusmol.com/dopamine-staining-in-embryonic-mouse-brain-html/ Dopamine antibody combined with STAINperfect immunostaining kit highlights dopaminergic fibers in embryonic mouse brain (E13.5) Using STAINperfect immunostaining kit A, the anti-Dopamine rabbit polyclonal antibody (Ref: IS1005) highlights dopaminergic fibers in embryonic mouse brain (E13. 5). The staining was performed following the optimized protocol for whole-mount samples and was revealed using Alexa Fluor® 488-conjugated secondary antibody. >>> GET YOUR STAINperfect TRIAL PACK ! --- - Published: 2015-09-28 - Modified: 2015-09-28 - URL: https://www.immusmol.com/istry-2015-congratulations-to-the-winners-of-our-quizz/ Back from the 2015 ISTRY conference, we would like to thanks the organizers for this fruitful event and congratulate the winners of our quizz. Back from the 2015 ISTRY conference, we would like to thanks the organizers for this fruitful event and congratulate the winners of our quizz: Valérie Autier (prize : Bordeaux Margaux 2012) Lena Brundin (prize : Champagne Ruinart) Rouba Kozak (prize : Burgundy - Gevrey Chambertin 2008) The products we presented at the 2015 conference of the International Society of Tryptophan Research (ISTRY): Kynurenine/Tryptophan ratio ELISA pack (download datasheeet) IHC-validated anti-Kynurenine primary antibody (view PLOS One article) --- - Published: 2015-09-16 - Modified: 2025-06-12 - URL: https://www.immusmol.com/istry-2015-conference-immusmol-congratulations-winners-quizz-html/ ImmuSmol is sponsoring the 2015 conference of the International Society for Tryptophan Research, taking place on September 16-18, at the Van Andel Research Institute in Grand Rapids, Michigan, USA. ImmuSmol is sponsoring the 2015 conference of the International Society for Tryptophan Research, taking place on September 16-18, at the Van Andel Research Institute in Grand Rapids, Michigan, USA. Meet Alban Bessède, CEO of ImmuSmol, there ! He will give a speech and run a booth. Please feel free to contact him before to arrange a meeting. --- - Published: 2015-09-16 - Modified: 2015-09-16 - URL: https://www.immusmol.com/the-kynurenine-pathway-is-activated-in-human-obesity-html/ ImmuSmol CEO Alban Bessede has contributed to a recent paper in Obesity : "The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation." ImmuSmol CEO Alban Bessede has contributed to a recent paper in Obesity : "The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation. " >>> Access the article on pubmed --- - Published: 2015-04-20 - Modified: 2015-04-20 - URL: https://www.immusmol.com/l-kynurenine-monoclonal-antibody-cancer-ido1-plos-one-html/ A recent PLOS ONE article shows that ImmuSmol's anti-L-Kynurenine-antibody can serve to stratify cancer patients for kynurenine pathway activity. Access the article... Recent data published in PLOS ONE demonstrate that ImmuSmol's anti-L-Kynurenine antibody can serve to stratify cancer patients for kynurenine pathway activity. Among key findings, data collected from human colorectal and breast cancer tissues highlights that IDO1 expression does not strictly match L-Kynurenine production. The article thus suggests that in situ detection of L-Kynurenine constitutes a powerful biomarker of IDO-1/-2 or TDO2 activity. Useful links: >>> Open-access PLOS ONE article >>> L-Kynurenine monoclonal antibody --- - Published: 2015-03-02 - Modified: 2025-06-12 - URL: https://www.immusmol.com/immune-brain-axis-from-molecules-to-behavior-html/ ImmuSmol is sponsoring the Symposium "The immune-brain axis: from molecules to behavior", held at the Hasselt University, Campus Diepenbeek, Belgium, on March 12th and 13th, 2015. ImmuSmol is supporting the Symposium "The immune-brain axis: from molecules to behavior", organized by the Hasselt University (Belgium) on March 12-13, 2015 ImmuSmol will be introducing to the scientific community 3 range products: High-sensisitve ELISA kits for neurotransmitters: Dopamine ELISA, Serotonin ELISA, Adrenaline ELISA, Noradrenaline ELISA The Kynurenine/Trytophan ratio ELISA pack Validated research antibodies to kynurenine pathway metabolites --- - Published: 2015-01-12 - Modified: 2025-06-12 - URL: https://www.immusmol.com/immusmol-small-molecule-antibodies-highlighted-in-press-html/ Discover ImmuSmol's story, featured in the 2015 winter edition of the European Biotechnology Magazine. The European Biotechnology Magazine dedicated a full-page article to ImmuSmol in its winter edition. Learn about the genesis of the company and its current lines of research based on small molecule antibodies. Access the article in pdf --- - Published: 2014-09-23 - Modified: 2025-06-12 - URL: https://www.immusmol.com/immusmol-raises-500-000-for-cancer-immunotherapy-in-vivo-proof-of-concept-html/ ImmuSmol is pleased to announce it has raised 500 000 € to progress its monoclonal antibodies for cancer immunotherapy to in vivo proof-of-concept (POC). ImmuSmol is pleased to announce it has raised 500 000 € to progress its monoclonal antibodies for cancer immunotherapy to in vivo proof-of-concept (POC). A fifty-fifty public/private financing This initial financing was supported by the Aquitaine Regional Council, Bpifrance, as well as private investors. ImmuSmol CEO Alban Bessede commented: "Small molecules have not yet been exploited as drug targets in the field of cancer immunotherapy. Our first in vivo results have confirmed the potency of our antibodies. With this additional funding, our goal is to establish a solid preclinical proof-of-concept, to set up new industrial or financial partnerships in 2015". Novel therapeutic & diagnostic tools for cancer immunotherapy While current antibody-based cancer immunotherapies concentrate on protein targets such as CTLA-4, PD-1 and PDL-1, ImmuSmol is targeting small molecules involved in tumor immune escape. « Over the last years, immune checkpoint inhibitors yielded exciting results, with unprecedented anti-tumor response on a long-term basis. Unfortunately, only a fraction of patients responds to these treatments” explains Alban Bessede. “With our small molecule antibodies, we aim at tackling two key challenges: to identify patients who might benefit from current cancer immunotherapies and to enhance their efficacy». Besides preclinical studies, ImmuSmol is thus currently collaborating with teams from Bordeaux’s comprehensive cancer center – the Institut Bergonié – to validate its biomarker approach in clinical samples. --- - Published: 2014-06-15 - Modified: 2014-06-15 - URL: https://www.immusmol.com/nature-article-alban-bessede-html/ Access latest article by ImmuSmol CEO Alban Bessède Access latest article by ImmuSmol CEO Alban Bessède: http://www. nature. com/nature/journal/vaop/ncurrent/full/nature13323. html --- - Published: 2014-06-13 - Modified: 2014-06-13 - URL: https://www.immusmol.com/polyclonal-antibodies-to-tryptophan-kynurenine-metabolites-rabbit-pab-ihc-validated-html/ NEW! ImmuSmol releases rabbit polyclonal antibodies against Tryptophan / Kynurenine metabolites, all validated for IHC in human samples. Picture: L-Kynurenine detection by IHC in human colorectal cancer tissue using anti-L-Kynurenine rabbit pAb. ImmuSmol is complementing its range of antibodies against kynurenine metabolites with a series of rabbit polyclonal antibodies (pAbs): Core advantages of rabbit pAbs Higher dilution: 1 vial generally caters for several hundred stainings Murine samples: no need for mouse on mouse kits Co-stainings: pAbs can be combined with mouse monoclonal antibodies to kynurenine metabolites Available rabbit polyclonal antibodies, validated for IHC: Anti L-Kynurenine rabbit polyclonal antibody Anti Quinolinic acid rabbit polyclonal antibody Anti Kynurenic acid rabbit polyclonal antibody Rabbit polyclonal antibodies under IHC validation: Anti Picolinic acid rabbit pAb Anti Quinaldic acid rabbit pAb Anti 3-Hydroxyanthranilic acid rabbit pAb Anti Xanthurenic acid rabbit pAb --- - Published: 2014-03-03 - Modified: 2014-03-03 - URL: https://www.immusmol.com/antibodies-against-small-molecules-html/ A short overview of ImmuSmol's services for the development of antibodies against small molecules, and their subsequent validation for small molecule detection by ELISA or IHC. Antibodies against small molecules constitute an easy, fast and cost-efficient alternative to HPLC and mass spectrometry when it comes to small molecule detection. ImmuSmol, in addition to developping antibodies against small molecule targets, offers to validate immunodetection protocols for small molecule visualization by IHC/IF, or quantification by ELISA. Core advantages of antibodies to small molecules Qualitative data: imaging of small molecules by IHC/IF in cells or tissues Fast quantification: 96-well plate ELISA format, 4-hour leadtime Ease of use & cost: - compatibility with routine immunodetection technologies >>> See case study on L-Kynurenine Applications and small molecule targets Small molecule biomarker detection: IHC or ELISA detection of amino acid metabolites, saccharids, lipids, steroids, nucleotides, ... Small molecule drug biovailability: assessment of drug penetration in tumor tissues by IHC or ability of drug compounds to cross the blood-brain barrier by IF or ELISA. Food safety and environmental diagnotics: fast ELISA detection of toxins, pollutants, drug and pesticide residues, ... 2 custom service offers Rabbit polyclonal antibodies against small molecules: Fast & cost-efficient development for research and diagnostic applications Mouse monoclonal antibodies against small molecules: Highly reproducible and scalable diagnostic tools for industrial applications --- - Published: 2014-02-20 - Modified: 2014-02-20 - URL: https://www.immusmol.com/small-molecule-detection-antibodies-html/ Small molecule antibodies constitute a powerful alternative to mass spec and aptamer-based technologies for small molecule detection, building on the advantages of existing immunodetection methods such as ELISA and IHC. Overview... Small molecule detection is traditionally associated with complex, time- and resource-consuming technologies. Here's an overview of how small molecule antibodies can facilitate research and diagnostic applications in the fields of human health, food safety and environemental monitoring. 1: A technology applicable to a wide range of small molecules Amino acid derivatives, saccharids, nucleotides, steroids, lipids... Antibodies can be raised against a variety of endogenous small molecules involved in pathological processes, thus opening up new avenues in research, diagnostics and theranostics. In the context of food safety and environemental monitoring, antibodies can also serve to detect small molecules such as drugs, pesticides residues and chemical pollutants. 2: A single antibody for any type of biological sample Unlike large molecules such as proteins, small molecules are conserved throughout species. Whether raised in mice or rabbit, a single small molecule antibody can thus detect its target in biological samples of any origin. Furthermore, small molecule antibodies are compatible with existing immunodetection technologies (IHC, IF, ELISA, WB, FACS, ... ), thus enabling the analysis of virtually any type of biological sample. 3: Qualitative and quantitative methods for small molecule detection In the context of an ELISA or EIA, antibodies raised against small molecules constitute an attractive alternative to mass spectrometry for small molecule quantification. Robust and highly sensitive, the immunoassay can be performed in almost any condition, while results, easily interpretable, are available within a few hours. The key application small molecule antibodies is undoubtly IHC/IF, allowing the visualization of small molecules in cell... --- > Anti-hapten antibodies enable the detection of small molecules using robust and rapid immunodetection technologies, such as ELISA and IHC/IF. Either raised against endogenous small molecules (amino acid metabolites, lipids, saccharids, nucleotides, steroids, ...) or exogenous compounds (drug and pesticide residues, chemical pollutants,...), anti-hapten antibodies constitute attractive detection tools in the field of human health, for diagnostic and theranostic applications, but also in areas such as food safety and environmental monitoring. - Published: 2014-02-15 - Modified: 2014-02-15 - URL: https://www.immusmol.com/anti-hapten-antibodies-small-molecule-detection-html/ A brief overview of ImmuSmol's antibody development services for the detection of small molecules in biological samples... Anti-hapten antibodies enable the detection of small molecules using robust and rapid immunodetection technologies, such as ELISA and IHC/IF. Either raised against endogenous small molecules (amino acid metabolites, lipids, saccharids, nucleotides, steroids, ... ) or exogenous compounds (drug and pesticide residues, chemical pollutants,... ), anti-hapten antibodies constitute attractive detection tools in the field of human health, for diagnostic and theranostic applications, but also in areas such as food safety and environmental monitoring. Specialized the development of anti-hapten antibodies, ImmuSmol offers custom services for the detection of small molecules in biological samples. Custom development of polyclonal or monoclonal anti-hapten antibodies 1: Antigen design Haptens are non-immunogenic small molecules which can only induce the production of antibodies when attached to a protein carrier. Based on the immuno-chemical properties of your target small molecule (chemical structure and composition, immunogenicity, competitors), our team develops specific "presentation strategies": cross-linking between the hapten and its protein carrier must expose the small molecule in a way that triggers the desired antibody response. 2: Anti-hapten antibody production Once synthesized, the hapten-carrier conjugate it is injected into a living animal for antibody production. ImmuSmol can either produce monoclonal or polyclonal antibodies: Anti-hapten mouse monoclonal antibodies - produced in vitro by a single immortalized cell clone, monoclonal antibodies are tailored for industrial applications, ensuring high reproducibility, availability and scalability. More about this service... Anti-hapten rabbit polyclonal antibodies - directly purified from rabbit serum 6 weeks after the first injection, polyclonals antibodies represent a fast and cost-effective approach, particularly suited for... --- --- ## Products > The anti-L-Threonine antibody IS1078 allows the detection of the proteinogenic amino acid L-Threonine in biological samples. Our team demonstrated the affinity and specificity of this polyclonal antibody, and we're currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. - Published: 2025-07-15 - Modified: 2025-07-15 - URL: https://www.immusmol.com/product/l-threonine-antibody-rabbit-polyclonal/ - SKU: IS1078 - Price: 449.00 EUR High specificity & affinity, IF / IHC / ICC The anti-L-Threonine antibody IS1078 allows the detection of the proteinogenic amino acid L-Threonine in biological samples. Our team demonstrated the affinity and specificity of this polyclonal antibody, and we're currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. --- > The anti-L-Leucine antibody IS1076 enables the detection of the essential amino acid L-Leucine in biological samples. Our team has validated the affinity and specificity of this polyclonal antibody. Compatible with STAINperfect immunostaining kit A, the antibody can be used for IF/ICC/IHC imaging applications. - Published: 2025-07-15 - Modified: 2025-07-16 - URL: https://www.immusmol.com/product/l-leucine-antibody-rabbit-polyclonal/ - SKU: IS1076 - Price: 449.00 EUR High specificity & affinity, IF / IHC / ICC The anti-L-Leucine antibody IS1076 enables the detection of the essential amino acid L-Leucine in biological samples. Our team has validated the affinity and specificity of this polyclonal antibody. Compatible with STAINperfect immunostaining kit A, the antibody can be used for IF/ICC/IHC imaging applications. --- > Highly affine and specific, the anti-L-Alanine antibody IS1075 enables the detection of non-essential amino acid α-alanine in biological samples. Combined with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody can stain L-Alanine in cells and tissues (IF/ICC/IHC protocols available). - Published: 2025-07-15 - Modified: 2025-07-23 - URL: https://www.immusmol.com/product/l-alanine-antibody-rabbit-polyclonal/ - SKU: IS1075 - Price: 449.00 EUR High specificity & affinity, IF / IHC / ICC Highly affine and specific, the anti-L-Alanine antibody IS1075 enables the detection of non-essential amino acid α-alanine in biological samples. Combined with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody can stain L-Alanine in cells and tissues (IF/ICC/IHC protocols available). --- > The anti-3-Hydroxykynurenine antibody IS1083 allows the detection of neurotoxic kynurenine metabolite 3-HK in biological samples. Our team developed and cross-validated by LC-MS an ELISA kit for 3-HK, based on this antibody. We're currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. - Published: 2025-07-15 - Modified: 2025-07-18 - URL: https://www.immusmol.com/product/3-hydroxykynurenine-antibody-rabbit-polyclonal/ - SKU: IS1083 - Price: 449.00 EUR High specificity & affinity, IF / IHC / ICC The anti-3-Hydroxykynurenine antibody IS1083 allows the detection of neurotoxic kynurenine metabolite 3-HK in biological samples. Our team developed and cross-validated by LC-MS an ELISA kit for 3-HK, based on this antibody. We're currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. --- > The anti-L-Tryptophan antibody IS1069 enables the detection of L-Tryptophan in biological samples. This rabbit polyclonal antibody can be combined with our range of mouse monoclonal antibodies to tryptophan downstream metabolites for multiplexed imaging. Requiring the use of the STAINperfect immunostaining kit A, the antibody is supplied with ready-to-use protocols for IF, ICC, and IHC applications. - Published: 2025-07-15 - Modified: 2025-07-23 - URL: https://www.immusmol.com/product/l-tryptophan-antibody-rabbit-polyclonal/ - SKU: IS1069 - Price: 449.00 EUR High specificity & affinity, IF / IHC / ICC The anti-L-Tryptophan antibody IS1069 enables the detection of L-Tryptophan in biological samples. This rabbit polyclonal antibody can be combined with our range of mouse monoclonal antibodies to tryptophan downstream metabolites for multiplexed imaging. Requiring the use of the STAINperfect immunostaining kit A, the antibody is supplied with ready-to-use protocols for IF, ICC, and IHC applications. --- > The 3-Hydroxy-Kynurenine (3-HK) ELISA Kit provides a simple, highly sensitive method for quantifying 3-HK in just 50 µL of plasma from any species. - Published: 2025-07-07 - Modified: 2025-07-24 - URL: https://www.immusmol.com/product/3-hydroxy-kynurenine-elisa-kit/ - SKU: IS-I-2900R - Price: 599.00 EUR High Sensitivity, Plasma samples (≥ 50µL) The 3-Hydroxy-Kynurenine (3-HK) ELISA Kit provides a simple, highly sensitive method for quantifying 3-HK in just 50 µL of plasma from any species. Cross-validated against LC-MS in human plasma, the kit is well-suited for in vitro, preclinical, and clinical studies. This kit is especially valuable for research into neurodegenerative and neuroinflammatory conditions—where neurotoxic, pro-oxidant 3-HK accumulates—such as Alzheimer’s, Huntington’s, and Parkinson’s diseases, as well as in major depressive disorder and schizophrenia. --- > The D-Serine ELISA Kit enables the easy and sensitive quantification of D-Serine (D-Ser) in plasma, serum, cerebrospinal fluid (CSF), and cell culture supernatants. Validated in human plasma samples, the assay requires only 50 μL of sample, making it suitable for both in vitro, preclinical, and clinical research applications. This kit is particularly relevant for studies investigating neurological disorders related to NMDA receptor and glutamatergic pathway dysfunctions, as well as for research into chronic kidney disease. - Published: 2025-05-15 - Modified: 2025-07-24 - URL: https://www.immusmol.com/product/d-serine-elisa-kit-plasma-serum-supernatant/ - SKU: IS-I-3400R - Price: 599.00 EUR High Sensitivity, Serum, plasma, CSF, supernatant (≥ 50µL) The D-Serine ELISA Kit enables the easy and sensitive quantification of D-Serine (D-Ser) in plasma, serum, cerebrospinal fluid (CSF), and cell culture supernatants. Validated in human plasma samples, the assay requires only 50 μL of sample, making it suitable for both in vitro, preclinical, and clinical research applications. This kit is particularly relevant for studies investigating neurological disorders related to NMDA receptor and glutamatergic pathway dysfunctions, as well as for research into chronic kidney disease. --- > Our XL ELISA pack of fast histamine tests for fish (fresh or frozen) and fish-derived products (canned fish, fish meal, etc.) allows the determination of histamine levels in 480 fish samples. Validated and certified by the AOAC Research Institute, our rapid assays can detect histamine levels between 0.44ppm and 300ppm within 25 minutes. - Published: 2025-05-13 - Modified: 2025-06-25 - URL: https://www.immusmol.com/product/fast-histamine-elisa-kit-histasure-xl/ - SKU: FC-E-3900 - Price: 1,799.00 EUR 480 determinations, Fast (30 min), Any fish sample (10g), Certified by the AOAC Our XL pack of fast histamine ELISA tests for fish (fresh or frozen) and fish-derived products (canned fish, fish meal, etc. ) allows the determination of histamine levels in 480 fish samples. Validated and certified by the AOAC Research Institute, our rapid tests can detect histamine levels between 0. 44 ppm and 300 ppm within 25 minutes. Product only available for customers outside of France. --- > Test the STAINperfect™ immunostaining kit in combination with 2 primary antibodies targeting neurotransmitters, amino acids, kynurenines, catecholamines, polyamines, etc... - Published: 2025-04-03 - Modified: 2025-07-23 - URL: https://www.immusmol.com/product/stainperfect-trial-pack/ - SKU: SP-T-0001 - Price: 387.00 EUR Try the STAINperfect kit with 2 antibodies among 30 (neurotransmitters, amino acids, metabolites...). The trial pack STAINperfect™ allows testing the STAINperfect™ immunostaining kit A in combination with 2 primary antibodies to key neurotransmitters and small molecules. The kit is provided with all necessary reagents and protocols to test the STAINperfect™ procedure in cell cultures, whole mounts, and tissue sections. --- > Highly affine and specific, the IS1066 anti-L-Histidine antibody can be used with the STAINperfect immunostaining kit A to perform ICC/IHC/IF stainings in cell cultures, whole mounts and tissue sections. - Published: 2025-03-17 - Modified: 2025-07-23 - URL: https://www.immusmol.com/product/l-histidine-antibody-rabbit-polyclonal/ - SKU: IS1066 - Price: 449.00 EUR High Specificity & Affinity, IF / IHC / ICC Highly affine and specific, the IS1066 anti-L-Histidine antibody can be used with the STAINperfect immunostaining kit A to perform ICC/IHC/IF stainings in cell cultures, whole mounts and tissue sections. --- > This anti-L-Citrulline antibody can be used in combination with the STAINperfect immunostaining kit A to visualize L-Citrulline in various types of samples (cell culture, tissue...). - Published: 2025-03-17 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-citrulline-antibody-rabbit-polyclonal/ - SKU: IS1067 - Price: 449.00 EUR High specificity & affinity, IF / IHC / ICC Validated by direct and competitive ELISA, this anti-L-Citrulline antibody is meant for IF/ICC/IHC use. Our team is currently working on the immunostaining protocol for optimal results with the STAINperfect immunostaining kit A. --- > This anti-L-Lysine antibody is the first and only antibody to date for the detection of L-Lysine (LYS) in biological samples. Used with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody can stain for L-Lysine in various types of samples (cell culture, tissue...). - Published: 2025-03-17 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-lysine-antibody-rabbit-polyclonal/ - SKU: IS1068 - Price: 449.00 EUR High specificity & affinity, IF / IHC / ICC This anti-L-Lysine antibody is the first and only antibody to date for the detection of L-Lysine (LYS) in biological samples. Our team is currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. --- > The anti-N1-Acetyl-Spermidine antibody IS1070 is, to date, the first and only antibody that enables the detection of this acetylated derivative of spermidine in biological samples. When used in conjunction with the STAINperfect Immunostaining Kit A, this rabbit polyclonal primary antibody can enable N1-Acetylspermidine imaging in various sample types, including cell cultures and tissues. - Published: 2025-03-17 - Modified: 2025-07-15 - URL: https://www.immusmol.com/product/n1-acetyl-spermidine-antibody-rabbit-polyclonal/ - SKU: IS1070 - Price: 449.00 EUR High specificity & affinity, IF / IHC / ICC The anti-N1-Acetyl-Spermidine antibody IS1070 is, to date, the first and only antibody that enables the detection of this acetylated derivative of spermidine in biological samples. Our team is currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. --- > The anti-N8-Acetyl-Spermidine antibody IS071 is the first and only antibody for the detection of the polyamine N8AS, derived from spermidine. Combined with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody can allow direct N8-Acetylspermidine visualization in various types of samples (cell culture, tissue...). - Published: 2025-03-17 - Modified: 2025-07-15 - URL: https://www.immusmol.com/product/n8-acetyl-spermidine-antibody-rabbit-polyclonal/ - SKU: IS1071 - Price: 449.00 EUR High specificity & affinity, IF / IHC / ICC The anti-N8-Acetyl-Spermidine antibody IS1071 is to date the first and only antibody that allows the detection of the polyamine N8AS in biological samples. Our team is currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. --- > This 5-HT antibody was valided on formalin-fixed paraffin-embedded (FFPE) specimens and used for immunochemistry and immunofluorescence applications. - Published: 2025-03-17 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/serotonin-antibody-for-ffpe-samples-rabbit-polyclonal/ - SKU: IS1086 - Price: 449.00 EUR Used for IF & IHC in FFPE samples of mouse brain & human colon tissues (manual & automated staining) This novel antibody raised against Serotonin (5-hydroxytryptamine, 5-HT) (#IS1086, polyclonal) is compatible with formalin-fixed biological materials. While allowing for the specific immunodetection of the serotonergic systems, our antibody has been validated for its use through immunochemistry and immunofluorescence applications on formalin-fixed paraffin-embedded (FFPE) samples originating from different species. --- > This Pregnenolone ELISA kit is designed for the quantitative measurement of the endogenous steroid pregnenolone in human serum samples. As a crucial downstream product of cholesterol metabolism, pregnenolone is instrumental in confirming the activity of CYP11A1 and 3β-HSD enzymes in both the gonads and adrenal glands. Accurate measurement of pregnenolone can therefore assist in identifying adrenal function disorders, such as congenital adrenal hyperplasia, endocrine tumors, and infertility. Moreover, because pregnenolone is a key precursor in the steroid hormone biosynthesis pathway, this kit is also well-suited for monitoring steroidogenesis—for example, in studies evaluating the impact of endocrine-disrupting chemicals (EDCs). - Published: 2025-02-19 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/pregnenolone-elisa-kit-i-fast-i-serum-samples/ - SKU: FR-E-2700 - Price: 279.00 EUR Fast (75 min), Serum, IVD (EU only) or RUO This Pregnenolone ELISA kit is designed for the quantitative measurement of the endogenous steroid pregnenolone in human serum samples. As a crucial downstream product of cholesterol metabolism, pregnenolone is instrumental in confirming the activity of CYP11A1 and 3β-HSD enzymes in both the gonads and adrenal glands. Accurate measurement of pregnenolone can therefore assist in identifying adrenal function disorders, such as congenital adrenal hyperplasia, endocrine tumors, and infertility. Moreover, because pregnenolone is a key precursor in the steroid hormone biosynthesis pathway, this kit is also well-suited for monitoring steroidogenesis—for example, in studies evaluating the impact of endocrine-disrupting chemicals (EDCs). --- > This ELISA kit enables quantitative measurement of testosterone in human saliva samples. It can be used to assess endocrine function, reproductive health, and hormonal variations in behavioral or metabolic studies. Designed for both in vitro diagnostic and research applications, the non-invasive saliva-based assay is provided in a 96-well plate format, allowing for high-throughput testing and efficient turnaround times. - Published: 2025-02-19 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/testosterone-elisa-kit-i-fast-i-human-saliva/ - SKU: SA-E-6100 - Price: 279.00 EUR Fast (90 min), Saliva, IVD (EU only) or RUO This ELISA kit enables quantitative measurement of testosterone in human saliva samples. It can be used to assess endocrine function, reproductive health, and hormonal variations in behavioral or metabolic studies. Designed for both in vitro diagnostic and research applications, the non-invasive saliva-based assay is provided in a 96-well plate format, allowing for high-throughput testing and efficient turnaround times. --- > This DHEA-S ELISA kit provides quantitative measurement of Dehydroepiandrosterone sulfate (DHEA-S) in human saliva samples, supporting the assessment of reproductive health and adrenal function. Suitable for both in vitro diagnostic and research applications, the non-invasive saliva-based assay is offered in a 96-well plate format, enabling high-throughput testing and streamlined turnaround times. - Published: 2025-02-19 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/dhea-s-elisa-kit-i-fast-i-human-saliva/ - SKU: SA-E-6500 - Price: 289.00 EUR Fast (30 min), Saliva, IVD (EU only) or RUO This DHEA-S ELISA kit provides quantitative measurement of Dehydroepiandrosterone sulfate (DHEA-S) in human saliva samples, supporting the assessment of reproductive health and adrenal function. Suitable for both in vitro diagnostic and research applications, the non-invasive saliva-based assay is offered in a 96-well plate format, enabling high-throughput testing and streamlined turnaround times. --- > This DHEA ELISA kit provides a quantitative method for measuring Dehydroepiandrosterone (DHEA) in human saliva, facilitating the evaluation of adrenal function and hormonal imbalances in reproductive, metabolic, and endocrine contexts. Designed for both in vitro diagnostic and research use, this non-invasive, saliva-based assay is provided in a 96-well plate format, supporting high-throughput testing and efficient turnaround times. - Published: 2025-02-19 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/dhea-elisa-kit-i-fast-i-human-saliva/ - SKU: SA-E-7000 - Price: 289.00 EUR Fast (90 min), Saliva, IVD (EU only) or RUO This DHEA ELISA kit provides a quantitative method for measuring Dehydroepiandrosterone (DHEA) in human saliva, facilitating the evaluation of adrenal function and hormonal imbalances in reproductive, metabolic, and endocrine contexts. Designed for both in vitro diagnostic and research use, this non-invasive, saliva-based assay is provided in a 96-well plate format, supporting high-throughput testing and efficient turnaround times. --- > This Androstenedione ELISA kit enables quantitative measurement of androstenedione in human saliva, supporting the evaluation of adrenal and gonadal function, as well as the monitoring of hormonal disorders such as polycystic ovary syndrome (PCOS) and hirsutism. Suitable for both in vitro diagnostic and research applications, it uses a non-invasive saliva-based format and comes in a 96-well plate, allowing for high-throughput testing and efficient turnaround times. - Published: 2025-02-19 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/androstenedione-elisa-kit-i-fast-i-human-saliva/ - SKU: SA-E-6700 - Price: 309.00 EUR Fast (75 min), Saliva, IVD (EU only) or RUO This Androstenedione ELISA kit enables quantitative measurement of androstenedione in human saliva, supporting the evaluation of adrenal and gonadal function, as well as the monitoring of hormonal disorders such as polycystic ovary syndrome (PCOS) and hirsutism. Suitable for both in vitro diagnostic and research applications, it uses a non-invasive saliva-based format and comes in a 96-well plate, allowing for high-throughput testing and efficient turnaround times. --- > The Chromogranin A ELISA kit delivers a straightforward, reliable method for quantifying CgA levels in serum samples, facilitating both the diagnosis and therapeutic monitoring of neuroendocrine tumors (NET)—including carcinoid tumors and pancreatic NETs. Beyond oncology, it also serves as a valuable tool in research on cardiovascular diseases and inflammatory disorders. With excellent correlation to Kryptor CgA II and proven diagnostic performance for GEP-NET, this assay supports rapid, high-precision screening for enhanced patient management and scientific investigation. - Published: 2025-02-18 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/chromogranin-a-elisa-i-serum-samples/ - SKU: TM-E-9000 - Price: 549.00 EUR Fast (2h30), Serum & Plasma, IVD (EU only) or RUO The Chromogranin A ELISA kit delivers a straightforward, reliable method for quantifying CgA levels in serum samples, facilitating both the diagnosis and therapeutic monitoring of neuroendocrine tumors (NET)—including carcinoid tumors and pancreatic NETs. Beyond oncology, it also serves as a valuable tool in research on cardiovascular diseases and inflammatory disorders. With excellent correlation to Kryptor CgA II and proven diagnostic performance for GEP-NET, this assay supports rapid, high-precision screening for enhanced patient management and scientific investigation. --- > This ELISA kit enables the measurement of progesterone levels in saliva, which increase significantly after ovulation. Highly relevant for fertility studies, this immunoassay can also be used to monitor early pregnancy, evaluate progesterone-based hormone therapies, and investigate endocrine disorders as well as stress-hormone interactions. Based on a 96-well plate format and offering a non-invasive sampling method, this rapid assay allows for longitudinal progesterone monitoring. - Published: 2025-02-14 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/progesterone-elisa-kit-fast-saliva/ - SKU: SA-E-6300 - Price: 309.00 EUR Fast (75 min), Saliva, IVD (EU only) or RUO This ELISA kit enables the measurement of progesterone levels in saliva, which increase significantly after ovulation. Highly relevant for fertility studies, this immunoassay can also be used to monitor early pregnancy, evaluate progesterone-based hormone therapies, and investigate endocrine disorders as well as stress-hormone interactions. Based on a 96-well plate format and offering a non-invasive sampling method, this rapid assay allows for longitudinal progesterone monitoring. --- > This ELISA kit enables the measurement of progesterone levels in serum and plasma samples. Progesterone measurement is widely used to confirm ovulation, monitor high-risk pregnancies, and evaluate hormone replacement therapy and IVF protocols. Beyond fertility and reproduction, this progesterone ELISA kit can also be used in the diagnosis of adrenal disorders and hormone-secreting tumors. - Published: 2025-02-14 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/progesterone-elisa-kit-i-fast-i-serum-and-plasma/ - SKU: FR-E-2500 - Price: 269.00 EUR Fast (75 min), Serum & Plasma, IVD (EU only) or RUO This ELISA kit enables the measurement of progesterone levels in serum and plasma samples. Progesterone measurement is widely used to confirm ovulation, monitor high-risk pregnancies, and evaluate hormone replacement therapy and IVF protocols. Beyond fertility and reproduction, this progesterone ELISA kit can also be used in the diagnosis of adrenal disorders and hormone-secreting tumors. --- > This ELISA kit quantitatively measures aldosterone, a mineralocorticoid hormone that regulates blood pressure and electrolyte balance, in human serum, plasma, and urine samples. The kit is relevant to assess endocrine function, renal physiology, and cardiovascular disorders. Designed for both in vitro diagnostic and research use, its 96-well plate format facilitates high-throughput testing and ensures fast turnaround times. - Published: 2025-02-13 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/aldosterone-elisa-kit-i-fast-i-human-serum-plasma-urine/ - SKU: MS-E-5200 - Price: 299.00 EUR Fast (2h), Human Serum, Plasma, Urine, IVD or RUO This ELISA kit quantitatively measures aldosterone, a mineralocorticoid hormone that regulates blood pressure and electrolyte balance, in human serum, plasma, and urine samples. The kit is relevant to assess endocrine function, renal physiology, and cardiovascular disorders. Designed for both in vitro diagnostic and research use, its 96-well plate format facilitates high-throughput testing and ensures fast turnaround times. --- > This ELISA kit enables the quantitative measurement of corticosterone in animal plasma and serum samples. Similar to cortisol in humans, corticosterone is a key stress hormone used to assess stress in animal models. Designed for both in vitro diagnostic and research use, its 96-well plate format facilitates high-throughput testing and ensures fast turnaround times. - Published: 2025-02-13 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/corticosterone-elisa-kit-i-fast-i-serum-and-plasma/ - SKU: MS-E-5400 - Price: 329.00 EUR Fast (75 min), Serum & Plasma, IVD (EU only) or RUO This ELISA kit enables the quantitative measurement of corticosterone in animal plasma and serum samples. Similar to cortisol in humans, corticosterone is a key stress hormone used to assess stress in animal models. Designed for both in vitro diagnostic and research use, its 96-well plate format facilitates high-throughput testing and ensures fast turnaround times. --- > This 25-OH Vitamin D ELISA kit allows for the precise quantification of 25-hydroxyvitamin D in both plasma and serum samples. 25-OH Vitamin D, which is synthesized in the liver from vitamin D, is crucial for evaluating vitamin D deficiency, affecting bone health, immune function, and muscle function. The kit is suitable for both in vitro diagnostic and research purposes, featuring a 96-well plate format that supports high-throughput testing and ensures rapid results. - Published: 2025-02-13 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/25-oh-vitamin-d-elisa-kit-i-fast-i-serum-and-plasma/ - SKU: MS-E-5800 - Price: 349.00 EUR Fast (1h45 min), Serum & Plasma, IVD (EU only) or RUO This 25-OH Vitamin D ELISA kit allows for the precise quantification of 25-hydroxyvitamin D in both plasma and serum samples. 25-OH Vitamin D, which is synthesized in the liver from vitamin D, is crucial for evaluating vitamin D deficiency, affecting bone health, immune function, and muscle function. The kit is suitable for both in vitro diagnostic and research purposes, featuring a 96-well plate format that supports high-throughput testing and ensures rapid results. --- > This 17-OH-Progesterone (17-OHP) ELISA kit enables the measurement of 17-hydroxyprogesterone in serum or plasma samples. As a precursor to cortisol and sex steroids, 17-OHP is typically measured to assess adrenal function and related disorders, such as hormonal imbalances and adrenal tumors. The kit is suitable for both in vitro diagnostic and research purposes, featuring a 96-well plate format that supports high-throughput testing and ensures rapid results. - Published: 2025-02-13 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/17-oh-progesterone-elisa-kit-i-fast-i-human-serum-and-plasma/ - SKU: FR-E-2800 - Price: 299.00 EUR Fast (90 min), Serum & Plasma, IVD (EU only) or RUO This 17-OH-Progesterone (17-OHP) ELISA kit enables the measurement of 17-hydroxyprogesterone in serum or plasma samples. As a precursor to cortisol and sex steroids, 17-OHP is typically measured to assess adrenal function and related disorders, such as hormonal imbalances and adrenal tumors. The kit is suitable for both in vitro diagnostic and research purposes, featuring a 96-well plate format that supports high-throughput testing and ensures rapid results. --- > This 17-OH-Progesterone (17-OHP) ELISA kit enables the measurement of active free 17-α-hydroxyprogesterone in saliva. As a precursor to cortisol and sex steroids, 17-OHP is commonly measured to evaluate adrenal function and associated conditions, including hormonal imbalances and adrenal tumors. The kit is designed for both in vitro diagnostic use and research applications, offering a 96-well plate format that facilitates high-throughput testing and delivers quick results. - Published: 2025-02-13 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/17-oh-progesterone-elisa-kit-i-fast-i-saliva/ - SKU: SA-E-6400 - Price: 289.00 EUR Fast (75 min), Saliva, IVD (EU only) or RUO This 17-OH-Progesterone (17-OHP) ELISA kit enables the measurement of active free 17-α-hydroxyprogesterone in saliva. As a precursor to cortisol and sex steroids, 17-OHP is commonly measured to evaluate adrenal function and associated conditions, including hormonal imbalances and adrenal tumors. The kit is designed for both in vitro diagnostic use and research applications, offering a 96-well plate format that facilitates high-throughput testing and delivers quick results. --- > This ELISA kit is designed to measure free estradiol levels in human saliva, supporting both research and diagnostic efforts in areas such as menstrual cycle monitoring, pregnancy assessment, menopause evaluation, endocrine disorder investigation, and the study of hormone-dependent cancers. - Published: 2025-02-13 - Modified: 2025-07-28 - URL: https://www.immusmol.com/product/estradiol-elisa-kit-human-saliva/ - SKU: SA-E-6200 - Price: 289.00 EUR Fast (3h), Saliva, IVD (EU only) or RUO This ELISA kit is designed to measure free estradiol levels in human saliva, supporting both research and diagnostic efforts in areas such as menstrual cycle monitoring, pregnancy assessment, menopause evaluation, endocrine disorder investigation, and the study of hormone-dependent cancers. --- > This Free Estriol ELISA Kit enables precise measurement of unconjugated estriol (E3) in serum samples. Determining estriol levels is relevant for monitoring fetal development and placental function, assessing gynecological and menopausal health, and characterizing estrogen metabolism. Suitable for both in vitro diagnostic and research applications, this rapid ELISA is provided in a 96-well plate format for fast turnaround times. - Published: 2025-02-13 - Modified: 2025-06-28 - URL: https://www.immusmol.com/product/free-estriol-elisa-kit-fast-serum/ - SKU: FR-E-2100 - Price: 279.00 EUR Fast (90 min), Serum, IVD (EU only) or RUO This Free Estriol ELISA Kit enables precise measurement of unconjugated estriol (E3) in serum samples. Determining estriol levels is relevant for monitoring fetal development and placental function, assessing gynecological and menopausal health, and characterizing estrogen metabolism. Suitable for both in vitro diagnostic and research applications, this rapid ELISA is provided in a 96-well plate format for fast turnaround times. --- > This Estrone ELISA kit provides accurate quantification of Estrone (E1) in serum and plasma. Measuring estrone is vital for evaluating postmenopausal estrogen levels, monitoring hormone replacement therapy (HRT), detecting estrogen-producing tumors, and investigating endocrine disorders. Suitable for both in vitro diagnostic and research applications, this rapid assay is supplied in a 96-well plate format to ensure fast turnaround times. - Published: 2025-02-13 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/estrone-elisa-kit-i-fast-i-serum-and-plasma/ - SKU: FR-E-2300 - Price: 279.00 EUR Fast (75 min), Serum & Plasma, IVD (EU only) or RUO This Estrone ELISA kit provides accurate quantification of Estrone (E1) in serum and plasma. Measuring estrone is vital for evaluating postmenopausal estrogen levels, monitoring hormone replacement therapy (HRT), detecting estrogen-producing tumors, and investigating endocrine disorders. Suitable for both in vitro diagnostic and research applications, this rapid assay is supplied in a 96-well plate format to ensure fast turnaround times. --- > This Estrone ELISA kit offers precise measurement of Estrone (E1) in saliva. Monitoring estrone levels is key for evaluating postmenopausal estrogen status, overseeing hormone replacement therapy (HRT), identifying estrogen-secreting tumors, and examining endocrine dysfunctions. Provided in a 96-well plate format, this rapid assay supports both in vitro diagnostic and research uses, ensuring swift turnaround times. - Published: 2025-02-13 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/estrone-elisa-kit-i-fast-i-saliva/ - SKU: SA-E-7100 - Price: 399.00 EUR Fast (75 min), Saliva, IVD (EU only) or RUO This Estrone ELISA kit offers precise measurement of Estrone (E1) in saliva. Monitoring estrone levels is key for evaluating postmenopausal estrogen status, overseeing hormone replacement therapy (HRT), identifying estrogen-secreting tumors, and examining endocrine dysfunctions. Provided in a 96-well plate format, this rapid assay supports both in vitro diagnostic and research uses, ensuring swift turnaround times. --- > This rapid ELISA kit quantitatively measures cortisol, the primary glucocorticoid in humans, in serum and plasma samples. Measuring stress hormone cortisol is crucial for assessing endocrine function (HPA axis), stress response, circadian rhythm, and disorders related to adrenal insufficiency. Designed for both in vitro diagnostic and research use, its 96-well plate format facilitates high-throughput testing and ensures fast turnaround times. - Published: 2025-02-12 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/cortisol-elisa-kit-i-fast-i-serum-and-plasma/ - SKU: MS-E-5000 - Price: 269.00 EUR Fast (75 min), Serum & Plasma, IVD (EU only) or RUO This rapid ELISA kit quantitatively measures cortisol, the primary glucocorticoid in humans, in serum and plasma samples. Measuring stress hormone cortisol is crucial for assessing endocrine function (HPA axis), stress response, circadian rhythm, and disorders related to adrenal insufficiency. Designed for both in vitro diagnostic and research use, its 96-well plate format facilitates high-throughput testing and ensures fast turnaround times. --- > This rapid ELISA kit is designed to quantitatively measure cortisol, a crucial stress hormone, in human urine (for adults). Measuring cortisol is essential for evaluating psychiatric disorders such as stress, depression, and anxiety, as well as sleep disorders and endocrine diseases. Suitable for both in vitro diagnostic and research purposes, the kit's 96-well plate format enables high-throughput testing and ensures quick results. - Published: 2025-02-12 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/cortisol-elisa-kit-fast-urine/ - SKU: MS-E-5100 - Price: 299.00 EUR Fast (75 min), Urine, IVD (EU only) or RUO This rapid ELISA kit is designed to quantitatively measure cortisol, a crucial stress hormone, in human urine (for adults). Measuring cortisol is essential for evaluating psychiatric disorders such as stress, depression, and anxiety, as well as sleep disorders and endocrine diseases. Suitable for both in vitro diagnostic and research purposes, the kit's 96-well plate format enables high-throughput testing and ensures quick results. --- > This ELISA kit is designed for quick and precise measurement of cortisol, a vital stress hormone, in human saliva. The determination of cortisol concentrations is relevant to assess stress levels and explore endocrine and metabolic disorders linked to the HPA axis. Suitable for both diagnostic and research use, this kit comes with a 96-well plate format, enabling efficient high-throughput testing and providing fast results. - Published: 2025-02-12 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/cortisol-elisa-kit-i-fast-i-human-saliva/ - SKU: SA-E-6000 - Price: 279.00 EUR Fast (90 min), Saliva, IVD (EU only) or RUO This ELISA kit is designed for quick and precise measurement of cortisol, a vital stress hormone, in human saliva. The determination of cortisol concentrations is relevant to assess stress levels and explore endocrine and metabolic disorders linked to the HPA axis. Suitable for both diagnostic and research use, this kit comes with a 96-well plate format, enabling efficient high-throughput testing and providing fast results. --- > This ELISA kit is designed to measure estradiol levels in serum and plasma samples, aiding research into menstrual cycles, pregnancy, menopause, endocrine disorders, and hormone-dependent cancers. Suitable for both in vitro diagnostic and research applications, its 96-well plate format facilitates high-throughput testing and rapid results. - Published: 2025-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/estradiol-elisa-kit-fast-serum-and-plasma/ - SKU: FR-E-2000 - Price: 269.00 EUR Fast (2h), Serum & Plasma, IVD (EU only) or RUO This ELISA kit is designed to measure estradiol levels in serum and plasma samples, aiding research into menstrual cycles, pregnancy, menopause, endocrine disorders, and hormone-dependent cancers. Suitable for both in vitro diagnostic and research applications, its 96-well plate format facilitates high-throughput testing and rapid results. --- > This DHEA ELISA kit provides quantitative measurement of Dehydroepiandrosterone (DHEA) in human serum and plasma, enabling the assessment of adrenal function and hormonal imbalances in reproductive, metabolic, and endocrine conditions. Designed for in vitro diagnostic and research applications, its 96-well plate format supports high-throughput screening and quick turnaround times for large-scale studies. - Published: 2025-01-31 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/dhea-elisa-kit-i-fast-i-serum-and-plasma-samples/ - SKU: AA-E-1600 - Price: 279.00 EUR Fast (90 min), Serum & Plasma, IVD (EU only) or RUO This DHEA ELISA kit provides quantitative measurement of Dehydroepiandrosterone (DHEA) in human serum and plasma, enabling the assessment of adrenal function and hormonal imbalances in reproductive, metabolic, and endocrine conditions. Designed for in vitro diagnostic and research applications, its 96-well plate format supports high-throughput screening and quick turnaround times for large-scale studies. --- > This Free Testosterone ELISA kit quantitatively measures unbound testosterone in serum, offering insights into androgen metabolism in conditions such as hypogonadism and hyperandrogenism. Developed for both in vitro diagnostic and research use, its 96-well plate format supports high-throughput testing and fast turnaround times. - Published: 2025-01-31 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/free-testosterone-elisa-kit-i-fast-i-serum/ - SKU: AA-E-1800 - Price: 279.00 EUR Fast (75 min), Serum, IVD (EU only) or RUO This Free Testosterone ELISA kit quantitatively measures unbound testosterone in serum, offering insights into androgen metabolism in conditions such as hypogonadism and hyperandrogenism. Developed for both in vitro diagnostic and research use, its 96-well plate format supports high-throughput testing and fast turnaround times. --- > This DHT ELISA kit quantitatively measures Dihydrotestosterone in human serum, offering insights into androgen-driven conditions, such as prostate disorders, acne, and alopecia. Developed for both in vitro diagnostic and research use, its 96-well plate format supports high-throughput testing and fast turnaround times. - Published: 2025-01-31 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/dht-elisa-kit-i-fast-i-human-serum/ - SKU: AA-E-1900 - Price: 279.00 EUR Fast (2h), Human serum, IVD (EU only) or RUO This DHT ELISA kit quantitatively measures Dihydrotestosterone in human serum, offering insights into androgen-driven conditions, such as prostate disorders, acne, and alopecia. Developed for both in vitro diagnostic and research use, its 96-well plate format supports high-throughput testing and fast turnaround times. --- > This DHEA-S ELISA kit enables the quantitative measurement of steroid hormone Dehydroepiandrosterone sulfate in human serum samples to evaluate reproductive health and adrenal function. Intended for in vitro diagnostics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. - Published: 2025-01-28 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/dhea-s-elisa-kit-fast-serum-samples/ - SKU: AA-E-1100 - Price: 269.00 EUR Fast (60 min), Serum, IVD (EU only) or RUO This DHEA-S ELISA kit enables the quantitative measurement of steroid hormone Dehydroepiandrosterone sulfate in human serum samples to evaluate reproductive health and adrenal function. Intended for in vitro diagnostics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. --- > This ELISA kit enables the quantitative measurement of Testosterone in serum and plasma samples to evaluate endocrine functions, reproductive health, and in the context of behavioral and metabolic conditions. Intended for in vitro diagnostics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. - Published: 2025-01-28 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/testosterone-elisa-kit-fast-serum-plasma-samples/ - SKU: AA-E-1300 - Price: 269.00 EUR Fast (75 min), Serum & Plasma, IVD (EU only) or RUO This ELISA kit enables the quantitative measurement of Testosterone in serum and plasma samples to evaluate endocrine functions, reproductive health, and in the context of behavioral and metabolic conditions. Intended for in vitro diagnostics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. --- > This Androstanediol-Glucuronide ELISA kit enables the quantitative measurement of C19 steroid 3α-Diol-G in human serum samples to evaluate androgen metabolism. Intended for in vitro diagnostics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. - Published: 2025-01-28 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/androstanediol-glucuronide-elisa-kit-i-fast-i-serum/ - SKU: AA-E-1500 - Price: 279.00 EUR Fast (45 min), Serum, IVD (EU only) or RUO This Androstanediol-Glucuronide ELISA kit enables the quantitative measurement of C19 steroid 3α-Diol-G in human serum samples to evaluate androgen metabolism. Intended for in vitro diagnostics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. --- > This FT3 ELISA kit is intended for the quantitative determination of Free Triiodothyronine (FT3) in serum, primarily for assessing thyroid function. Designed for both in vitro diagnostic purposes and research applications, this efficient and reliable assay (75 minutes) utilizes a 96-well plate format, making it ideal for high-throughput screening with quick turnaround times. - Published: 2025-01-27 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/ft3-elisa-kit-fast-serum/ - SKU: TF-E-2100 - Price: 249.00 EUR Fast (75 min), Serum, IVD (EU only) or RUO This FT3 ELISA kit is intended for the quantitative determination of Free Triiodothyronine (FT3) in serum, primarily for assessing thyroid function. Designed for both in vitro diagnostic purposes and research applications, this efficient and reliable assay (75 minutes) utilizes a 96-well plate format, making it ideal for high-throughput screening with quick turnaround times. --- > This FT4 ELISA kit is designed for the quantitative measurement of Free Thyroxine (FT4) in serum, primarily to evaluate thyroid function. Suitable for both in vitro diagnostic applications and research purposes, this reliable and efficient assay (75 minutes) features a 96-well plate format, making it optimal for high-throughput screening with fast turnaround times. - Published: 2025-01-27 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/ft4-elisa-kit-fast-serum/ - SKU: TF-E-2200 - Price: 249.00 EUR Fast (75 min), Serum, IVD (EU only) or RUO This FT4 ELISA kit is designed for the quantitative measurement of Free Thyroxine (FT4) in serum, primarily to evaluate thyroid function. Suitable for both in vitro diagnostic applications and research purposes, this reliable and efficient assay (75 minutes) features a 96-well plate format, making it optimal for high-throughput screening with fast turnaround times. --- > This TSH ELISA kit is designed for the quantitative measurement of thyrotropin (TSH) in serum and heparin-plasma samples, primarily to evaluate thyroid gland function. Suitable for both in vitro diagnostic use and research applications, this fast and reliable assay (120 minutes) employs a 96-well plate format, making it well-suited for high-throughput screening with rapid turnaround times. - Published: 2025-01-27 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/tsh-elisa-kit-fast-serum-plasma/ - SKU: TF-E-2000 - Price: 249.00 EUR Fast (2h), Serum & Plasma, IVD (EU only) or RUO This TSH ELISA kit is designed for the quantitative measurement of thyrotropin (TSH) in serum and heparin-plasma samples, primarily to evaluate thyroid gland function. Suitable for both in vitro diagnostic use and research applications, this fast and reliable assay (120 minutes) employs a 96-well plate format, making it well-suited for high-throughput screening with rapid turnaround times. --- > This Reverse T3 ELISA kit is intended for the quantitative measurement of reverse Triiodothyronine (rT3) in serum and plasma samples (EDTA, lithium heparin, or citrate) to assess thyroid function. Designed for both in vitro diagnostic and research applications, this fast and reliable assay (105 minutes) utilizes a 96-well plate format, making it ideal for high-throughput screening with quick turnaround times. - Published: 2025-01-24 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/reverse-t3-rt3-elisa-kit-fast-serum-plasma/ - SKU: TF-E-2500 - Price: 249.00 EUR Fast (105 min), Serum & Plasma, IVD (EU only) or RUO This Reverse T3 ELISA kit is intended for the quantitative measurement of reverse Triiodothyronine (rT3) in serum and plasma samples (EDTA, lithium heparin, or citrate) to assess thyroid function. Designed for both in vitro diagnostic and research applications, this fast and reliable assay (105 minutes) utilizes a 96-well plate format, making it ideal for high-throughput screening with quick turnaround times. --- > This T4 ELISA kit is designed for the quantitative determination of total Thyroxine in serum and plasma samples (EDTA, lithium heparin, or citrate) to evaluate thyroid dysfunction. Suitable for both in vitro diagnostic and research purposes, this rapid assay (100 minutes) features a 96-well plate format, enabling efficient screening of large experimental series with minimal turnaround time. - Published: 2025-01-23 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/t4-elisa-kit-fast-serum-plasma/ - SKU: TF-E-2400 - Price: 249.00 EUR Fast (100 min), Serum & Plasma, IVD (EU only) or RUO This T4 ELISA kit is designed for the quantitative determination of total Thyroxine in serum and plasma samples (EDTA, lithium heparin, or citrate) to evaluate thyroid dysfunction. Suitable for both in vitro diagnostic and research purposes, this rapid assay (100 minutes) features a 96-well plate format, enabling efficient screening of large experimental series with minimal turnaround time. --- > This T3 ELISA kit enables the quantitative measurement of triiodothyronine in serum and plasma (EDTA) samples to assess thyroid function. Intended for in vitro diagnostics and research applications, this fast test (70 min) comes in 96-well plate format, allowing the screening of large experimental series within short lead times. - Published: 2025-01-09 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/t3-elisa-kit-fast-serum-plasma/ - SKU: TF-E-2300 - Price: 249.00 EUR Fast (70 min), Serum & Plasma, IVD (EU only) or RUO This T3 ELISA kit enables the quantitative measurement of triiodothyronine in serum and plasma (EDTA) samples to assess thyroid function. Intended for in vitro diagnostics and research applications, this fast test (70 min) comes in 96-well plate format, allowing the screening of large experimental series within short lead times. --- > This Androstenedione ELISA kit enables the quantitative measurement of steroid hormone androstenedione in serum and plasma (EDTA) samples. Intended for in vitro diagnotics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. - Published: 2025-01-06 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/androstenedione-elisa-kit-fast-serum-plasma/ - SKU: AA-E-1000 - Price: 269.00 EUR Fast (90 min), Serum & Plasma, IVD (EU only) or RUO This Androstenedione ELISA kit enables the quantitative measurement of steroid hormone androstenedione in serum and plasma (EDTA) samples. Intended for in vitro diagnotics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. --- > Measuring the Citrulline-to-Arginine ratio is indicative of nitric oxide synthase (NOS) activity, which converts Arginine into Citrulline and Nitric Oxide (NO). A decreased plasma CIT-to-ARG ratio thus suggests high NO production, and may serve as a biomarker in metabolic and cardiovascular conditions. - Published: 2024-09-23 - Modified: 2025-06-30 - URL: https://www.immusmol.com/product/citrulline-to-arginine-ratio-elisa-pack-serum-plasma/ - SKU: ISE-0510R - Price: 1,049.00 EUR High Sensitivity, Plasma & Serum (≥ 20µL) Measuring the Citrulline-to-Arginine ratio is indicative of nitric oxide synthase (NOS) activity, which converts Arginine into Citrulline and Nitric Oxide (NO). A decreased plasma CIT-to-ARG ratio thus suggests high NO production, and may serve as a biomarker in metabolic and cardiovascular conditions. --- > This ELISA pack provides an easy way to assess the plasma/serum Global Arginine Bioavailability Ratio (GABR), defined as arginine/[ornithine + citrulline]. The GABR indicates the availability of arginine for Nitric Oxide production. Low GABR may serve to assess endothelial dysfunction, atherosclerosis, and cardiovascular disorders. - Published: 2024-09-23 - Modified: 2025-07-02 - URL: https://www.immusmol.com/product/global-arginine-bioavailability-ratio-gabr-elisa-pack-serum-plasma/ - SKU: ISE-451000R - Price: 1,499.00 EUR High Sensitivity, Plasma & Serum (≥ 20µL) This ELISA pack provides an easy way to assess the plasma/serum Global Arginine Bioavailability Ratio (GABR), defined as arginine/. The GABR indicates the availability of arginine for Nitric Oxide production. Low GABR may serve to assess endothelial dysfunction, atherosclerosis, and cardiovascular disorders. --- > The Citrulline ELISA kit allows easy and accurate quantification of L-citrulline in plasma samples. Plasma citrulline (CIT) can serve as a biomarker to assess intestinal health (enterocyte function) and disorders related to the urea cycle and nitric oxide biosynthesis (see our L-Arginine ELISA kit). With a minimal sample volume of 20 µL and a detection limit of 1.47 μM, the kit enables working with samples of human and animal origin. - Published: 2024-09-20 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/citrulline-elisa-kit-highly-sensitive-plasma/ - SKU: IS I-1500R - Price: 599.00 EUR High Sensitivity, Plasma (≥ 20µL) The Citrulline ELISA kit allows easy and accurate quantification of L-citrulline in plasma samples. Plasma citrulline (CIT) can serve as a biomarker to assess intestinal health (enterocyte function) and disorders related to the urea cycle and nitric oxide biosynthesis (see our L-Arginine ELISA kit). With a minimal sample volume of 20 µL and a detection limit of 1. 47 μM, the kit enables working with samples of human and animal origin. --- > The Melatonin ELISA kit enables the accurate quantification of N-acetyl-5-methoxy-tryptamine (Melatonin) in plasma and serum samples. - Published: 2024-08-21 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/melatonin-elisa-kit-highly-sensitive-serum-plasma-samples/ - SKU: BA-E-3300R - Price: 599.00 EUR High sensitivity, 500µl plasma or serum The Melatonin ELISA kit allows for the easy and accurate quantification of N-acetyl-5-methoxy-tryptamine (melatonin) in plasma and serum samples. With a detection limit of 1. 6 pg/mL, the kit enables the measurement of melatonin in blood during both daytime (0 to 20 pg/mL) and nighttime (40 to 100 pg/mL). --- > The N1-Acetyl-Spermidine ELISA Kit enables simple, sensitive, and accurate quantification of the polyamine N1-acetylspermidine in biological fluids, including plasma, serum, and cell culture supernatants. Cross-validated against LC-MS in human plasma, the assay delivers reliable results using just 50 µL of sample. Compatible with samples from any species, this kit is suited for both preclinical research and clinical studies. - Published: 2023-09-07 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/n1-acetyl-spermidine-elisa-kit/ - SKU: IS-I-2400R - Price: 599.00 EUR High Sensitivity, Serum, Plasma, Cell Culture Supernatant (≥ 50µL) The N1-Acetyl-Spermidine ELISA Kit enables simple, sensitive, and accurate quantification of the polyamine N1-acetylspermidine in biological fluids, including plasma, serum, and cell culture supernatants. Cross-validated against LC-MS in human plasma, the assay delivers reliable results using just 50 µL of sample. Compatible with samples from any species, this kit is suited for both preclinical research and clinical studies. --- > The N8-Acetyl-Spermidine ELISA Kit enables simple, sensitive, and accurate quantification of the polyamine N8-acetylspermidine in biological fluids, including plasma, serum, and cell culture supernatants. Cross-validated against LC-MS in human plasma, the assay delivers reliable results using just 50 µL of sample. Compatible with samples from any species, this kit is suited for both preclinical research and clinical studies. - Published: 2023-09-07 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/n8-acetyl-spermidine-elisa-kit/ - SKU: IS-I-2500R - Price: 599.00 EUR High Sensitivity, Serum, Plasma, Cell Culture Supernatant (≥ 20µL) The first and only ELISA kit for the quantification of N8-Acetyl-Spermidine (N8-AcSpdn) in plasma, serum, tissue homogenates and cell supernatants. Highly sensitive, compatible with any species, this kit enables accurate measurements of N8-AcSpdn in low-volume samples (>20µL). --- > Arginine-to-Ornithine ratio ELISA: Detection in 20 µL serum or plasma (any species). Sensitivity 2.1 µM / 8.5 µM; range 5–200 µM. - Published: 2023-05-22 - Modified: 2025-07-30 - URL: https://www.immusmol.com/product/arginine-ornithine-elisa-pack/ - SKU: ISE-0410R - Price: 1,049.00 EUR High Sensitivity, Plasma & Serum (≥ 20µL) With the Arginine‑to‑Ornithine Ratio ELISA Pack, quantify L‑Arginine and L‑Ornithine from just 20 µL of serum or plasma (any species) in one overnight assay, delivering fast, accurate insight into arginine‑pathway activity and immune regulation without relying on LC‑MS. --- > The Ornithine ELISA kit allows the easy and highly sensitive measurement of L-Ornithine (Orn) in biological samples from any species. Cross-validated by LC-MS in human plasma samples, the kit was used in recent papers to determine ornithine levels in human & mouse cell culture supernatants. - Published: 2023-05-17 - Modified: 2025-07-11 - URL: https://www.immusmol.com/product/ornithine-elisa-kit/ - SKU: IS-I-1000R - Price: 599.00 EUR High Sensitivity, Plasma (≥ 20µL), Cited in literature The Ornithine ELISA kit allows the easy and highly sensitive measurement of L-Ornithine (Orn) in biological samples from any species. Cross-validated by LC-MS in human plasma samples, the kit was used in recent papers to determine ornithine levels in human & mouse cell culture supernatants. --- > The IS-I-1300R ELISA kit enables the sensitive and quantitative measurement of L-Histidine (His) in plasma samples from any species. Cross-validated against LC-MS in human plasma, the assay offers high sensitivity and requires only 10 µL of sample, making it fit for both preclinical research and clinical studies. - Published: 2022-09-21 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/l-histidine-elisa-kit/ - SKU: IS-I-1300R - Price: 599.00 EUR High Sensitivity, Plasma (≥ 10µL) The IS-I-1300R ELISA kit enables the sensitive and quantitative measurement of L-Histidine (His) in plasma samples from any species. Cross-validated against LC-MS in human plasma, the assay offers high sensitivity and requires only 10 µL of sample, making it fit for both preclinical research and clinical studies. --- > Accurate and easy-to-implement ELISA kit for L-Asparagine (Asn) quantitation functions, in plasma samples. Min. sample volume: 20μL. Sensitivity: 2.3µM. - Published: 2022-05-04 - Modified: 2025-07-21 - URL: https://www.immusmol.com/product/l-asparagine-elisa-kit/ - SKU: IS-I-1600R - Price: 599.00 EUR High Sensitivity, Plasma (≥ 20µL) The L-Asparagine (Asn) ELISA kit enables the quantitative measurement of the conditionally non-essential amino acid L-Asparagine in plasma samples. Validated in human plasma with a strong correlation to LC-MS data, the assay is highly sensitive, user-friendly, and requires only 20 µL of sample. Its ease of use and low sample volume make it ideally suited for both preclinical research and clinical studies. --- > This is the first and only anti-3-Hydroxy-Anthranilic acid (3-HAA) rabbit polyclonal antibody available for research use. Confirmed to be highly specific and affine by competitive ELISA, the antibody is currently being validated for IHC and IF use. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/3-hydroxyanthranilic-acid-antibody-pab/ - SKU: IS1008 - Price: 449.00 EUR Only rabbit pAb available to 3-HAA This is the first and only anti-3-Hydroxy-Anthranilic acid (3-HAA) rabbit polyclonal antibody available for research use. Confirmed to be highly specific and affine by competitive ELISA, the antibody is currently being validated for IHC and IF use. --- > IS009 was the first anti-Xanthurenic acid antibody made available to the scientific community, back in 2014. This mouse mAb was validated for IHC and IF in human midbrain tissues, highlighting cytoplasmic presence of xanthurenic acid. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/xanthurenic-acid-antibody-mab/ - SKU: IS009 - Price: 449.00 EUR First primary mAb available, Validated for IF & IHC in FFPE brain tissues IS009 was the first anti-Xanthurenic acid antibody made available to the scientific community, back in 2014. This mouse mAb was validated for IHC and IF in human midbrain tissues, highlighting cytoplasmic presence of xanthurenic acid. --- > Intended for research use, this add-on kit to the BA-E-1000R Histamine ELISA kit enables the measurement of histamine release in heparinized whole blood samples, allowing for instance to determine the sensitivity of basophilic granulocytes to specific allergens. - Published: 2022-02-11 - Modified: 2025-06-25 - URL: https://www.immusmol.com/product/histamine-release-kit-whole-blood-samples/ - SKU: BA-E-1100R - Price: 149.00 EUR Add-on kit for histamine release measurement in whole blood (640µL) Intended for research use, this add-on to the BA-E-1000R histamine ELISA kit enables the measurement of histamine release in heparinized whole blood samples, allowing for instance to determine the sensitivity of basophilic granulocytes to specific allergens. --- > This Glutamate ELISA kit enables the quantitative measurement of L-Glutamic acid in a variety of biological samples, including cell cultures, tissue homogenates, urine, plasma, serum, etc. - Published: 2022-02-11 - Modified: 2025-07-15 - URL: https://www.immusmol.com/product/glutamate-elisa-kit-any-sample/ - SKU: BA-E-2400 - Price: 599.00 EUR Any sample, IVD (EU only) or RUO, Cited in 5 papers Intended for in vitro diagnostics & research use, this Glutamate ELISA kit enables the quantitative measurement of L-Glutamic acid in a variety of biological samples, including cell cultures, tissue homogenates, urine, plasma, serum, etc. --- > The Kynurenine/Tryptophan ratio ELISA pack enables quantitative measurements of tryptophan catabolism along the kynurenine pathway in large numbers of samples. The two kits included in the pack are ready to use. Highly sensitive, with a minimum sample volume of 20µl, they permit the performance of longitudinal studies in mice. - Published: 2022-02-11 - Modified: 2025-07-17 - URL: https://www.immusmol.com/product/kynurenine-tryptophan-ratio-elisa-pack/ - SKU: ISE-2227R - Price: 1,049.00 EUR High Sensitive, ≥ 20µL Biological fluids, Cited in 50+ papers This Kynurenine to Tryptophan ratio ELISA pack provides a reliable, quantitative method for measuring tryptophan catabolism via the kynurenine pathway across a large number of samples. The pack includes two ready-to-use, highly sensitive kits that require only 20 µL of sample per test. Compatible with any species, the kit allows the performance of longitudinal studies in small animals, such as mice. --- > The anti-Octopamine antibody IS1033 was validated for immunofluorescence in crayfish brain tissues, using the STAINperfect immunostaining kit A for sample preparation. In combination with the staining kit, this rabbit polyclonal antibody can label Octopamine in cell cultures and tissues for IF/IHC imaging. - Published: 2022-02-11 - Modified: 2025-07-22 - URL: https://www.immusmol.com/product/octopamine-antibody-rabbit-pab/ - SKU: IS1033 - Price: 449.00 EUR Validated for IF in brain tissues The anti-Octopamine antibody IS1033 was validated for immunofluorescence in crayfish brain tissues, using the STAINperfect immunostaining kit A for sample preparation. In combination with the staining kit, this rabbit polyclonal antibody can label Octopamine in cell cultures and tissues for IF/IHC imaging. --- > The anti-dopamine antibody IS1005 was used in recent papers stain mouse primary neurons, human brain tissues, brain organoids, and C. Elegans. - Published: 2022-02-11 - Modified: 2025-07-28 - URL: https://www.immusmol.com/product/dopamine-antibody-validated-if/ - SKU: IS1005 - Price: 449.00 EUR Used for IF in primary & iPS-derived neurons, organoids & brain tissues. Cited in 10+ papers The anti-dopamine antibody IS1005 is a rabbit polyclonal antibody that binds dopamine (3,4‑dihydroxy‑phenethylamine) with high affinity and no detectable cross‑reactivity to L‑DOPA or tyramine. Validated for whole‑mount, cell‑culture and tissue‐section immunofluorescence when paired with STAINperfect™ kit A, it lets researchers map dopamine across species, see for instance recent publications in mouse primary neurons, rodent & human brain tissues, human iPS-derived brain organoids, and whole animals (C. elegans). --- > This research kit enables the ultra-sensitve measurement of histamine in any biological sample: tissue homogeneates, cell culture supernatants, body fluids, etc. With a minimal sample volume as low as 10µl, this histamine immunoassay allows longitudinal studies in mice and rat models. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/histamine-elisa-kit-any-sample/ - SKU: BA-E-5800R - Price: 599.00 EUR Ultra-Sensitive, ≥10µl samples, Cited in 6 papers This research Histamine ELISA kit enables the ultra-sensitive measurement of histamine in any biological sample: tissue homogenates, cell culture supernatants, body fluids, etc. With a minimal sample volume as low as 10µl, this histamine immunoassay allows longitudinal studies in mice and rat models. --- > This Serotonin (5-HT) ELISA kit is tailored for the rapid measurement of 5-hydroxytryptamine in serum, urine and platelets. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay enables the determination of serotonin levels in up to 40 samples within 75 minutes. - Published: 2022-02-11 - Modified: 2025-07-23 - URL: https://www.immusmol.com/product/serotonin-elisa-kit-serum-urine-platelets/ - SKU: BA-E-8900 - Price: 429.00 EUR Fast (75 min), Min. vol. ≥25µL, Cited in literature The Fast Serotonin ELISA Kit is a reliable assay (LC-MS cross-validation) designed for the quantitative measurement of 5-hydroxytryptamine (serotonin) in serum, urine, and platelet samples within 75 minutes. Applicable to any species, the kit has been cited in peer-reviewed publications for quantifying serotonin in human samples, for instance in the context of autism and post-traumatic stress disorder (PTSD). With low minimal sample volume of 25µL, it has also been successfully applied to mouse and chicken samples. --- > This rabbit polyclonal anti-glycine antibody was validated for immunofluorescence (IF) in mouse primary cortical neurons using the STAINperfect immunostaining kit A. When combined with the kit, this antibody enables direct visualization of glycine in cell cultures, whole mounts, and tissue sections. - Published: 2022-02-11 - Modified: 2025-07-23 - URL: https://www.immusmol.com/product/glycine-antibody-rabbit-pab/ - SKU: IS1034 - Price: 449.00 EUR Validated for IF in primary neurons. Cited in literature This rabbit polyclonal anti-glycine antibody was validated for immunofluorescence (IF) in mouse primary cortical neurons using the STAINperfect immunostaining kit A. When combined with the kit, this antibody enables direct visualization of glycine in cell cultures, whole mounts, and tissue sections. --- > The IS-I-1100 Gln ELISA kit allows for the determination of L-Glutamine in plasma, serum and cell culture supernatants originating from either preclinical or clinical samples, of a volume as low as 10μL and with a sensitivity of 3µM. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/l-glutamine-elisa-kit/ - SKU: IS-I-1100R - Price: 599.00 EUR High Sensitivity, Plasma, Serum, Supernatant (≥ 10µL) The IS-I-1100R Glutamine ELISA kit enables the sensitive and quantitative determination of L-Glutamine (Gln) in plasma, serum, and cell culture supernatants. Cross-validated against LC-MS in human plasma samples, the assay has also been successfully applied to both human and mouse cell culture models (see supporting data). Species-independent and requiring as little as 10 µL of sample, the kit combines high sensitivity with ease of use, making it an ideal tool for both preclinical research and clinical studies. --- > The rabbit polyclonal anti-serotonin antibody IS1035 was validated using the STAINperfect immunostaining kit A in mouse primary neurons, mouse brain tissues, and crayfish brain tissues, demonstrating robust and specific labeling of serotonin (5-HT). - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/serotonin-antibody-goat-pab/ - SKU: IS1035 - Price: 449.00 EUR Validated for IF in primary neurons & brain tissues The rabbit polyclonal anti-serotonin antibody IS1035 was validated using the STAINperfect immunostaining kit A in mouse primary neurons, mouse brain tissues, and crayfish brain tissues, demonstrating robust and specific labeling of serotonin (5-HT). --- > This high-sensitive Histamine ELISA kit is tailored for the monitoring of histamine in food and beverage samples, including fish and fish products, sausages, dairy products and wine. Simple and rapid, the test displays high correlation with HPLC. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/histamine-elisa-kit-any-food-or-beverage/ - SKU: FC-E-3100 - Price: 349.00 EUR Fast (75 min), for fish, meat, cheese, milk, wine, ... This highly sensitive Histamine ELISA kit is tailored for the measurement of histamine in food and beverage samples, including fish and fish products, sausages, dairy products and wine. Simple and rapid, the test displays high correlation with HPLC. This product is only available for customers outside of France. --- > Our team validated the chicken polyclonal anti-GABA antibody IS1036 for immunofluorescence (IF) in mouse primary neurons and crayfish tissues using the STAINperfect immunostaining kit A. This antibody supports multiplex staining with rabbit polyclonal or mouse monoclonal antibodies. In recent papers, it allowed specific visualization of gamma-aminobutyric acid (GABA) in human iPSC-derived neurons, mouse primary neurons, and mouse brain tissues. - Published: 2022-02-11 - Modified: 2025-07-15 - URL: https://www.immusmol.com/product/gaba-antibody-chicken-pab/ - SKU: IS1036 - Price: 449.00 EUR Validated for IF in primary & iPS-derived neurons, and brain tissues. Cited in literature Our team validated the chicken polyclonal anti-GABA antibody IS1036 for immunofluorescence (IF) in mouse primary neurons and crayfish tissues using the STAINperfect immunostaining kit A. This antibody supports multiplex staining with rabbit polyclonal or mouse monoclonal antibodies. In recent papers, it allowed specific visualization of gamma-aminobutyric acid (GABA) in human iPSC-derived neurons, mouse primary neurons, and mouse brain tissues. --- > Ultra‑sensitive Serotonin ELISA – detect 5 pg / mL from just 1 µL of any sample • Validated across all species • Cited in 25 papers • Ships same day - Published: 2022-02-11 - Modified: 2025-07-29 - URL: https://www.immusmol.com/product/serotonin-elisa-kit-any-sample/ - SKU: BA-E-5900R - Price: 599.00 EUR Ultra-Sensitive, Min. Vol. ≥1µL, Cited in 25 papers This Serotonin (5-HT) ELISA kit enables the ultra-sensitive measurement of 5-hydroxytryptamine (5-HT) in any biological sample. Intended for research use only, the assay features a lower limit of detection at 5pg/ml and a minimal sample volume as low as 1µl. --- > This fast Histamine ELISA kit was validated and certified by the AOAC Research Institute as an effective method for the quantitative measurement of histamine in fresh, frozen, canned fish samples and fish meals. Performed within 25 minutes, the assay can detect histamine levels between 0,44 ppm and 300ppm in any fish sample, thus complying with regulatory requirements. Product only available for customers outside of France. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/histamine-elisa-kit-any-fish-sample/ - SKU: FC-E-3600 - Price: 269.00 EUR 48 determinations, Fast (30 min), Any fish sample (10g), Certified by the AOAC This fast Histamine ELISA kit was validated and certified by the AOAC Research Institute as an effective method for the quantitative measurement of histamine in fresh, frozen, canned fish samples and fish meals. Performed within 25 minutes, the assay can detect histamine levels between 0,44 ppm and 300ppm in any fish sample, thus complying with regulatory requirements. Product only available for customers outside of France. --- > The anti-tryptophan antibody IS011 was validated in mouse and crayfish brain tissues using the STAINperfect Immunostaining Kit A. Additionally, this monoclonal antibody has been successfully used in recent scientific publications to stain human cells and mouse kidney tissue sections. - Published: 2022-02-11 - Modified: 2025-07-18 - URL: https://www.immusmol.com/product/l-tryptophan-mab/ - SKU: IS011 - Price: 449.00 EUR Used for IF in rodent brain & renal tissues, and human cell cultures. Cited in literature The anti-tryptophan antibody IS011 was validated in mouse and crayfish brain tissues using the STAINperfect Immunostaining Kit A. Additionally, this monoclonal antibody has been successfully used in recent scientific publications to stain human cells and mouse kidney tissue sections. --- > The anti-kynurenic acid (KYNA) rabbit polyclonal antibody IS1011 was successfully validated for immunohistochemistry (IHC) on human paraffin-embedded brain tissues. Optimal staining was achieved at a 1:2000 dilution, with a single vial sufficient for approximately 400 stainings. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/kynurenic-acid-antibody-pab/ - SKU: IS1011 - Price: 449.00 EUR Validated for IHC in FFPE human brain tissues The anti-kynurenic acid (KYNA) rabbit polyclonal antibody IS1011 was successfully validated for immunohistochemistry (IHC) on human paraffin-embedded brain tissues. Optimal staining was achieved at a 1:2000 dilution, with a single vial sufficient for approximately 400 stainings. --- > Accurate and easy-to-implement ELISA kit for L-Phenylalanine (Phe) quantification in plasma and sera samples. The assay requires a sample volume as low as 20μL and is characterized by a 1.7µM sensitivity - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/l-phenylalanine-elisa-kit/ - SKU: IS-I-1700R - Price: 599.00 EUR High Sensitivity, Plasma & Serum (≥ 20µL), Cited in literature The L-Phenylalanine ELISA kit enables the sensitive and quantitative measurement of the essential amino acid L-Phenylalanine (Phe) in biological fluids. Validated in human plasma with strong concordance to LC-MS data, the assay has also been successfully applied to alternative matrices such as human sweat. Species-independent, highly sensitive, and requiring only 20 µL of sample, the kit is user-friendly and well-suited for a broad range of research applications—from preclinical to clinical studies. --- > Our anti-Quinaldic acid antibody is the only primary antibody available to date to stain for quinaldic acid. This mouse monoclonal antibody was validated by our team for immunohistochemistry (IHC) and immufluorescence (IF) in paraffin-embedded tissues from human caudate-putamen region. - Published: 2022-02-11 - Modified: 2025-07-23 - URL: https://www.immusmol.com/product/quinaldic-acid-antibody-mab/ - SKU: IS004 - Price: 449.00 EUR Only Quinaldic acid antibody on the market. Validated for IF and IHC in FFPE brain tissues Our anti-Quinaldic acid antibody is the only primary antibody available to date to stain for quinaldic acid. This mouse monoclonal antibody was validated by our team for immunohistochemistry (IHC) and immufluorescence (IF) in paraffin-embedded tissues from human caudate-putamen region. --- > The anti-Noradrenaline (NA) antibody IS1042 was validated for immunofluorescence in mouse brain and spinal cord tissues, in combination with the STAINperfect immunostaining kit A. This anti-Norepinephrine antibody was also used to evidence noradrenergic neurons in spider brain (Jin et al, Nature Ecology & Evolution, 2023). - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-noradrenaline-antibody-norepinephrine-rabbit-ab/ - SKU: IS1042 - Price: 449.00 EUR Validated for IF brain & spinal cord tissues I Cited in literature The anti-Noradrenaline (NA) antibody IS1042 was validated for immunofluorescence in mouse brain and spinal cord tissues, in combination with the STAINperfect immunostaining kit A. This anti-Norepinephrine antibody was recently used to evidence noradrenergic neurons in spider brain (Jin et al, Nature Ecology & Evolution, 2023). --- > This ELISA kit is tailored for the rapid measurement of Adrenaline (Epinephrine) in urine and plasma samples. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay enables to determine Epinephrine levels in up to 40 samples within 4 hours. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/epinephrine-elisa-kit-urine-plasma-samples/ - SKU: BA-E-6100 - Price: 499.00 EUR Fast (4h), 300µl plasma / 10µl urine, In vitro diagnostics & Research This Epinephrine ELISA kit is tailored for the rapid measurement of Adrenaline (Epinephrine) in urine and plasma samples. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay enables to determine Epinephrine levels in up to 40 samples in duplicate within 4 hours. --- > Anti-Serotonin antibody IS040, in combination with the STAINperfect immunostaining kit A, enables reliable detection of 5-HT in whole mounts, cell cultures, and tissue sections. Our team successfully used this antibody to stain embryonic mouse tissues, and recent studies have demonstrated its effectiveness in visualizing serotonin in human midbrain organoids and mouse brain tissues. - Published: 2022-02-11 - Modified: 2025-07-08 - URL: https://www.immusmol.com/product/serotonin-antibody-mouse-mab/ - SKU: IS040 - Price: 449.00 EUR Used for IF in brain organoids and tissues. Cited in literature Anti-Serotonin antibody IS040, in combination with the STAINperfect immunostaining kit A, enables reliable detection of 5-HT in whole mounts, cell cultures, and tissue sections. Our team successfully used this antibody to stain embryonic mouse tissues, and recent studies have demonstrated its effectiveness in visualizing serotonin in human midbrain organoids and mouse brain tissues. --- > L-Serine ELISA kit for the determination of Ser in cell culture supernatant, serum and plasma samples, with a minimal sample volume of 20μL. The kit is easy to implement and well suited for both preclinical and clinical studies. - Published: 2022-02-11 - Modified: 2025-07-17 - URL: https://www.immusmol.com/product/l-serine-elisa-kit/ - SKU: IS-I-1200R - Price: 599.00 EUR High Sensitivity, Serum, Plasma, Supernatant (≥ 20µL) The L-Serine ELISA Kit enables the quantitative determination of the amino acid and neurotransmitter L-Serine (Ser) in cell culture supernatants, serum, and plasma samples, requiring only 20 μL of sample. Easy to use, this reseach assay is optimized for both preclinical research and clinical studies. --- > This ELISA kit enables the ultra-sensitive measurement of Adrenaline (Epinephrine) in any biological sample. Intended for research use only, the assay features a lower limit of detection at 3.3 pg/ml and a minimal sample volume as low as 1µl. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/epinephrine-elisa-kit-any-sample/ - SKU: BA-E-5100R - Price: 599.00 EUR Ultra-Sensitive, Any sample ≥ 1 µl, Research use only This research Epinephrine ELISA kit enables the ultra-sensitive measurement of Adrenaline (Epinephrine) in any biological sample from any species. Intended for research use, the assay features a lower limit of detection at 3. 3 pg/ml and a minimal sample volume as low as 1µL. --- > The first and only anti-3-HydroxyAnthranilic acid mouse antibody available for research use. This primary mouse monoclonal antibody was validated for IHC both in human tumor and brain tissues. When tested by competitive ELISA, the antibody demonstrated strong affinity and high specificity. - Published: 2022-02-11 - Modified: 2025-07-29 - URL: https://www.immusmol.com/product/3-hydroxyanthranilic-acid-mab/ - SKU: IS001 - Price: 449.00 EUR Used for IHC in FFPE brain, lung, tumor tissues. Only 3-HAA mAb available. Cited in 3 papers The first and only anti-3-HydroxyAnthranilic acid mouse antibody available for research use. This primary mouse monoclonal antibody was validated for IHC in human tumor and brain tissues. When tested by competitive ELISA, the antibody demonstrated strong affinity and high specificity. --- > Used with the STAINperfect immunostaining kit A, the anti-GABA antibody IS039 allows to label Gamma-Aminobutyric acid in cell cultures, whole mounts and tissue sections, evidencing GABAergic systems (cell bodies and neuritic network). We successfully performed GABA stainings in rat primary neurons with this antibody, and a recent publication used this anti-GABA antibody in human iPS-derived midbrain organoids. Our range also includes polyclonal anti-GABA antibodies: Rabbit pAb #IS1006, Chicken pAb#IS1036. - Published: 2022-02-11 - Modified: 2025-07-17 - URL: https://www.immusmol.com/product/gaba-antibody-mouse-mab/ - SKU: IS039 - Price: 449.00 EUR Validated IF in primary neurons & brain organoids. Cited in literature Used with the STAINperfect immunostaining kit A, the anti-GABA antibody IS039 allows to label Gamma-Aminobutyric acid in cell cultures, whole mounts and tissue sections, evidencing GABAergic systems (cell bodies and neuritic network). We successfully performed GABA stainings in rat primary neurons with this antibody, and a recent publication used this anti-GABA antibody in human iPS-derived midbrain organoids. Our range also includes polyclonal anti-GABA antibodies: Rabbit pAb #IS1006, Chicken pAb#IS1036. --- > Easy-to-use & highly sensitive assay for the quantification of L-Kynurenine across large series of samples. The KYN ELISA features a lower limit of detection at 45.7ng/ml and a minimal sample volume of 20µl, thus allowing longitudinal studies in mice. It is available in RUO and IVD (In vitro diagnostics) formats. - Published: 2022-02-11 - Modified: 2025-07-28 - URL: https://www.immusmol.com/product/l-kynurenine-elisa-kit/ - SKU: BA-E-2200 - Price: 599.00 EUR High Sensitivity, biological fluids (≥ 20µL), cited in 68 papers The L-Kynurenine ELISA kit is a user-friendly and highly sensitive assay designed for reliable quantification of kynurenine in a wide range of biological samples. Optimized for use with plasma, serum, and cell culture supernatants, this assay requires only 20 µL of sample and offers a low detection limit of 45. 7 ng/mL—ideal for longitudinal studies, even in small animal models such as mice. Validated across multiple species, the KYN ELISA has been successfully used in peer-reviewed studies to measure kynurenine levels in human, monkey, dog, pig, mouse, rat, rabbit, cattle, and insect samples. Whether you're conducting basic research, preclinical studies, or clinical investigations, this versatile kit ensures accurate and reproducible results across large sample sets. --- > This 5-hydroxyindoleacetic acid ELISA kit is tailored for the rapid measurement of 5-HIAA in urine samples. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay can be performed within 3 hours. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/5-hiaa-elisa-kit-urine-samples/ - SKU: BA-E-1900 - Price: 399.00 EUR Fast (3h), Urine (≥50µl), IVD (EU only) and RUO This 5-hydroxyindoleacetic acid (5-HIAA) ELISA kit is tailored for the rapid measurement of 5-HIAA in urine samples. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay can be performed within 3 hours. --- > This mouse monoclonal antibody to Quinolinic acid was validated for IF & IHC in human brain tissues. Recent publications relied on this antibody to stain for neurotoxin Quinolinic acid in mouse brain tissues and human atheroma plaques. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/quinolinic-acid-mab/ - SKU: IS002 - Price: 449.00 EUR Validated for IF & IHC in FFPE brain tissues I Cited in literature This mouse monoclonal antibody to Quinolinic acid was validated for IF & IHC in human brain tissues. Recent publications relied on this antibody to stain for neurotoxin Quinolinic acid in mouse brain tissues and human atheroma plaques. --- > Validated for immunohistochemical analysis in paraffin-embedded human parkinsonian brain specimens, this anti-Quinolinic acid (QUIN) rabbit polyclonal antibody was recently employed in scientific publications to confirm the presence of Quinolinic acid in FFPE brain and lung tissues using both immunohistochemistry (IHC) and immunohistofluorescence (IHF). - Published: 2022-02-11 - Modified: 2025-07-08 - URL: https://www.immusmol.com/product/quinolinic-acid-antibody-pab/ - SKU: IS1010 - Price: 449.00 EUR Validated for IHC in human brain & lung FFPE samples, Cited in literature Validated for immunohistochemical analysis in paraffin-embedded human parkinsonian brain specimens, this anti-Quinolinic acid (QUIN) rabbit polyclonal antibody was recently employed in scientific publications to confirm the presence of Quinolinic acid in FFPE brain and lung tissues using both immunohistochemistry (IHC) and immunohistofluorescence (IHF). --- > This Norepinephrine ELISA kit is tailored for the rapid measurement of Noradrenaline (Norepinephrine) in urine and plasma samples. Intended for in vitro diagnostics, this fast-track quantitative immunoassay enables to determine Norepinephrine levels in up to 40 samples within 4 hours. - Published: 2022-02-11 - Modified: 2025-07-30 - URL: https://www.immusmol.com/product/norepinephrine-elisa-kit-urine-plasma-samples/ - SKU: BA-E-6200 - Price: 499.00 EUR Fast assay (4h), Cited in 8 papers This Norepinephrine ELISA kit is tailored to rapidly measure Noradrenaline (Norepinephrine) in urine and plasma samples. Intended for in vitro diagnostics & research use, this fast-track quantitative immunoassay enables to determine Norepinephrine levels in up to 40 samples within 4 hours. --- > Validated ELISA kit for Lysine (Lys) quantitation in plasma samples. Accurate and easy-to-implement. Low minimal sample volume: 20μL. 13µM sensitivity. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/l-lysine-elisa-kit/ - SKU: IS-I-1400R - Price: 599.00 EUR High Sensitivity, Plasma (≥ 20µL) The IS-I-1400R ELISA kit enables the sensitive and quantitative determination of the essential amino acid L-Lysine (Lys) in plasma samples from any species. Cross-validated against LC-MS in human plasma, the assay combines high sensitivity with low sample volume requirements (20 µL), making it ideally suited for both preclinical research and clinical applications. --- > The anti-histamine antibody IS1039 is a rabbit polyclonal antibody developed to label Histamine in whole mounts, cell culture and tissue sections. The antibody was validated for IF in mouse and crayfish brain tissues, using the STAINperfect immunostaining kit A. - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/histamine-antibody-rabbit-pab/ - SKU: IS1039 - Price: 449.00 EUR Validated for IF in mouse & crayfish brain tissues The anti-histamine antibody IS1039 is a rabbit polyclonal antibody developed to label Histamine in whole mounts, cell culture and tissue sections. The antibody was validated for IF in mouse and crayfish brain tissues, using the STAINperfect immunostaining kit A. --- > This is the first and only anti-Picolinic acid antibody available for research use. Confirmed to be highly specific and affine by competitive ELISA, this rabbit polyclonal antibody is undergoing validation for IHC and IF use. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/picolinic-acid-pab/ - SKU: IS1015 - Price: 449.00 EUR First & Only anti-Picolinic acid antibody This is the first and only anti-Picolinic acid antibody available for research use. Confirmed to be highly specific and affine by competitive ELISA, this rabbit polyclonal antibody is undergoing validation for IHC and IF use. --- > The first and only validated anti-Cinnabarinic acid antibody available for research use. IHC validation of this mouse mAb in human brain and breast tumor tissues revealed the presence, in specific cells, of Cinnabarinic acid, a tryptophan metabolite known for its immunomodulatory role. A 2020 paper also used this anti-cinnabarinic antibody to stain mouse brain tissue sections (immunofluorescence). - Published: 2022-02-11 - Modified: 2025-07-29 - URL: https://www.immusmol.com/product/cinnabarinic-acid-mab/ - SKU: IS005 - Price: 449.00 EUR Used for IF & IHC in brain & cancer tissues I Cited in literature The first and only validated anti-Cinnabarinic acid antibody available for research use. IHC validation of this mouse mAb in human brain and breast tumor tissues revealed the presence, in specific cells, of Cinnabarinic acid, a tryptophan metabolite known for its immunomodulatory role. A 2020 paper also used this anti-cinnabarinic antibody to stain mouse brain tissue sections (immunofluorescence). --- > Ultra-Sensitive Norepinephrine ELISA kit (Noradrenaline). Any species, Any Sample (min. vol. 1µl). LoD: 1.3pg/ml. Cited in 30+ papers - Published: 2022-02-11 - Modified: 2025-07-31 - URL: https://www.immusmol.com/product/norepinephrine-elisa-kit-any-sample/ - SKU: BA-E-5200R - Price: 599.00 EUR Ultra Sensitive, Any sample ≥ 1µL, Use Research use This research Norepinephrine ELISA kit enables the ultra-sensitive measurement of Noradrenaline (Norepinephrine, NE) in any biological sample. Intended for research use only, the assay features a lower limit of detection at 1. 3 pg/mL and a minimal sample volume as low as 1µL. --- > IS1014 was the first anti-Xanthurenic acid cited in the literature, by Roussel et al., in 2016. In this paper, this highly affine rabbit pAb was used to label Xanthurenic acid in mouse brain tissue sections and rat primary neurons. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/xanthurenic-acid-pab/ - SKU: IS1014 - Price: 449.00 EUR Used for IF in primary neurons & brain tissues I Cited in literature IS1014 was the first anti-Xanthurenic acid cited in the literature, by Roussel et al. , in 2016. In this paper, this highly affine rabbit pAb was used to label Xanthurenic acid in mouse brain tissue sections and rat primary neurons. --- > This Metanephrine ELISA kit enables the measurement of free L-metanephrine in plasma samples with high sensitivity. Intended for in vitro diagnostics (EU only) & research use, this quantitative immunoassay is based on a simple and fast sample preparation protocol, and offers a limit of detection below 15pg/ml. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/metanephrine-elisa-kit-plasma-samples/ - SKU: BA-E-8100 - Price: 549.00 EUR High Sensitive, Fast, Plasma, IVD (EU only) or Research use This Metanephrine ELISA kit enables the measurement of free L-metanephrine in plasma samples with high sensitivity. Intended for in vitro diagnostics (EU only) & research use, this quantitative immunoassay is based on a simple and fast sample preparation protocol, and offers a limit of detection below 15pg/ml. --- > This Epinephrine/Norepinephrine ELISA kit enables the ultra-sensitive measurement of Adrenaline (Epinephrine) and Noradrenaline (Norepinephrine) in any biological sample. Intended for research use, the assay features a lower limit of detection at 6.6pg/ml and a minimal sample volume as low as 1µl. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/epinephrine-norepinephrine-elisa-kit-any-sample/ - SKU: BA-E-5400R - Price: 999.00 EUR Ultra-Sensitive, Any sample ≥ 1 µl, Research use only This research Epinephrine/Norepinephrine ELISA kit enables the ultra-sensitive measurement of Adrenaline (Epinephrine) and Noradrenaline (Norepinephrine) in any biological sample. Intended for research use only, the assay features a lower limit of detection at 6. 6pg/ml and a minimal sample volume as low as 1µl. --- > The anti-3-Methoxytyramine (3-MT) antibody IS1019 is a rabbit polyclonal antibody validated for IF in mouse brain tissues (whole mounts, free-floating sections). In samples prepared with the STAINperfect immunostaining kit A, this antibody allows direct 3MT visualization in whole mounts, cell cultures and tissue sections. - Published: 2022-02-11 - Modified: 2025-07-02 - URL: https://www.immusmol.com/product/3-mt-antibody-3-methoxytyramine-rabbit-pab/ - SKU: IS1019 - Price: 449.00 EUR Validated for IF in brain tissues The anti-3-Methoxytyramine (3-MT) antibody IS1019 is a rabbit polyclonal antibody validated for IF in mouse brain tissues (whole mounts, free-floating sections). In samples prepared with the STAINperfect immunostaining kit A, this antibody allows direct 3MT visualization in whole mounts, cell cultures and tissue sections. --- > This Metanephrine ELISA kit enables to quantify metanephrine in urine samples within 2 hours. Intended for in vitro diagnostics (EU only) & research use, this quantitative immunoassay demonstrated good correlation with HPLC. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/metanephrine-elisa-kit-urine-samples/ - SKU: BA-E-8400 - Price: 499.00 EUR Fast ( This Metanephrine ELISA kit enables to quantify metanephrine in urine samples within 2 hours. Intended for in vitro diagnostics (EU only) & research use, this quantitative immunoassay demonstrated good correlation with HPLC. --- > The Quinolinic Acid ELISA kit is optimized for the quantitation of Quinolinic Acid within serum and plasma samples. Working with a low sample volume of 25µL, this assay enables pre-clinical and clinical sample testing. - Published: 2022-02-11 - Modified: 2025-07-02 - URL: https://www.immusmol.com/product/quinolinic-acid-elisa-kit/ - SKU: IS-I-0100R - Price: 599.00 EUR High Sensitivity, Serum, Plasma (≥ 25µL), Cited in 10 papers. The Quinolinic Acid ELISA kit is optimized for sensitive quantification of the neurotoxin quinolinic acid (QA, also known as QUIN) in serum or plasma. This user‑friendly competitive assay works equally well for small pilot studies and high‑throughput projects. It requires only 25 µL of sample per well and is species‑independent, making it suitable for both pre‑clinical and clinical research. The kit has already been used to measure QA in mouse and human plasma, serum, and cell‑culture supernatants across studies on cancer, cardiovascular disease, and neuroinflammatory conditions such as bipolar disorder, multiple sclerosis, and autism spectrum disorder. --- > The Kynurenic Acid ELISA kit is optimized for the quantitation of Kynurenic Acid (KYNA) within serum samples. Working with a 50µL sample volume, this assay enables pre-clinical and clinical sample testing. - Published: 2022-02-11 - Modified: 2025-07-28 - URL: https://www.immusmol.com/product/kynurenic-acid-elisa-kit/ - SKU: IS-I-0200R - Price: 599.00 EUR High Sensitivity. Serum. Min. vol. 50µL. Cited in 7 papers. The Kynurenic Acid ELISA kit is optimized for sensitive quantification of kynurenic acid (KYNA) in serum. This competitive, user‑friendly assay is species‑independent and requires only 50 µL of sample, making it well-suited for research applications. Researchers have already applied it to human serum, plasma, and cell‑culture supernatants to investigate neuroinflammatory disorders—including Alzheimer’s disease, COVID‑19, multiple sclerosis, bipolar disorder, and autism spectrum disorder—as well as cancer. --- > This fast-track ELISA kit is tailored for the rapid measurement of Adrenaline (Epinephrine) and Noradrenaline (Norepinephrine) in urine and plasma samples. This quantitative immunoassay enables to determine Epinephrine & Norepinephrine levels in up to 40 samples in duplicate within 4 hours. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/epinephrine-norepinephrine-elisa-kit-plasma-urine/ - SKU: BA-E-6500 - Price: 699.00 EUR Fast (4h), 300µl plasma or 10µl urine, Cited in literature This Epinephrine/Norepinephrine ELISA kit is tailored for the rapid measurement of Adrenaline (Epinephrine) and Noradrenaline (Norepinephrine) in urine and plasma samples. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay enables to determine Epinephrine & Norepinephrine levels in up to 40 samples (in duplicate) within 4 hours. --- > This Normetanephrine ELISA kit enables the fast measurement of free L-Normetanephrine in plasma samples. Intended for in vitro diagnostics (EU only) & research use, this quantitative immunoassay is based on a simple and fast sample preparation protocol, and offers a limit of detection below 18pg/ml. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/normetanephrine-elisa-kit-plasma-samples/ - SKU: BA-E-8200 - Price: 549.00 EUR High sensitivity, Fast, Plasma, IVD (EU only) or Research use This Normetanephrine ELISA kit enables the fast measurement of free L-Normetanephrine in plasma samples. Intended for in vitro diagnostics (EU only) & research use, this quantitative immunoassay is based on a simple and fast sample preparation protocol, and offers a limit of detection below 18pg/ml. --- > This Normetanephrine ELISA kit enables to quantify normetanephrine in urine samples within 2 hours. Intended for in vitro diagnostics (EU only) & research use, this quantitative immunoassay demonstrated good correlation with HPLC. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/normetanephrine-elisa-kit-urine-samples/ - SKU: BA-E-8500 - Price: 499.00 EUR Fast ( This Normetanephrine ELISA kit enables to quantify normetanephrine in urine samples within 2 hours. Intended for in vitro diagnostics (EU only) & research use, this quantitative immunoassay demonstrated good correlation with HPLC. --- > This 3 catecholamines ELISA kit is tailored for the rapid measurement of Adrenaline (Epinephrine), Noradrenaline (Norepinephrine) and Dopamine in urine and plasma samples. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay can be performed in samples from any species within 5 hours. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/3-catecholamines-elisa-kit-plasma-urine-samples/ - SKU: BA-E-6600 - Price: 1,099.00 EUR Fast (5h), Dopamine / Epinephrine / Norepinephrine in Urine & Plasma, Cited in 5 papers This 3 catecholamines ELISA kit is tailored for the rapid measurement of Adrenaline (Epinephrine), Noradrenaline (Norepinephrine) and Dopamine in urine and plasma samples. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay can be performed in samples from any species within 5 hours. --- > This Free Metanephrines ELISA kit enables the fast measurement of free L-metanephrine and free L-Normetanephrine in plasma samples. Intended for research use and in vitro diagnostics (EU only), this quantitative immunoassay is based on a simple and fast sample preparation step, and features a limit of detection below 25pg/ml. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/free-metanephrine-normetanephrine-elisa-kit-plasma-samples/ - SKU: BA-E-8300 - Price: 949.00 EUR Fast, Plasma, IVD (EU only) or Research use This Free Metanephrines ELISA kit enables the fast measurement of free L-metanephrine and free L-Normetanephrine in plasma samples. Intended for research use and in vitro diagnostics (EU only), this quantitative immunoassay is based on a simple and fast sample preparation step, and features a limit of detection below 25pg/ml. --- > The anti-L-DOPA antibody IS1030 was validated for immunofluorescence in crayfish tissues and mouse primary neurons using the STAINperfect immunostaining kit A, demonstrating specific and accurate labeling of L-DOPA. - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-dopa-antibody-rabbit-pab/ - SKU: IS1030 - Price: 449.00 EUR Validated for IF in primary neurons & tissues The anti-L-DOPA antibody IS1030 was validated for immunofluorescence in crayfish tissues and mouse primary neurons using the STAINperfect immunostaining kit A, demonstrating specific and accurate labeling of L-DOPA. --- > This Catecholamine ELISA kit enables the ultra-sensitive measurement of Epinephrine, Norepinephrine and Dopamine in any biological sample. Intended for research use only, the assay features a lower limit of detection at 6.6pg/ml and a minimal sample volume as low as 1µl. - Published: 2022-02-11 - Modified: 2025-07-15 - URL: https://www.immusmol.com/product/3-catecholamines-elisa-kit-any-sample/ - SKU: BA-E-5600R - Price: 1,299.00 EUR Ultra-Sensitive, Any sample ≥ 1 µl, Research use only This research Catecholamine ELISA kit enables the ultra-sensitive measurement of Epinephrine, Norepinephrine and Dopamine in any biological sample. Intended for research use only, the assay features a lower limit of detection at 6. 6 pg/mL and a minimal sample volume as low as 1µl. --- > This Metanephrines ELISA kit enables to quantify metanephrine and normetanephrine in urine samples within 2 hours. Intended for in vitro diagnostics & Research, this quantitative immunoassay demonstrated good correlation with HPLC. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/metanephrine-normetanephrine-elisa-kit-urine-samples/ - SKU: BA-E-8600 - Price: 579.00 EUR Fast ( This Metanephrines ELISA kit enables to quantify metanephrine and normetanephrine in urine samples from any species within 2 hours. Intended for in vitro diagnostics & research, this quantitative immunoassay demonstrated good correlation with HPLC. --- > The Kynurenine/Kynurenic Acid/Quinolinic acid ELISA pack enables quantitative measurements of tryptophan catabolism along the kynurenine pathway in large numbers of samples. Highly sensitive, with a minimum sample volume of 25-50µL, they enable pre-clinical and clinical sample testing. - Published: 2022-02-11 - Modified: 2025-07-18 - URL: https://www.immusmol.com/product/kynurenine-kynurenic-acid-quinolinic-acid-elisa-pack-3-kyns-elisa-pack/ - SKU: ISE-220102R - Price: 1,499.00 EUR High Sensitivity. Plasma, Serum. Min. Vol. 25-50µL. Cited in literature The Kynurenine / Kynurenic Acid / Quinolinic Acid ELISA Pack delivers rapid, quantitative insight into tryptophan catabolism across large sample sets. Supplied as three ready-to-use kits for research use only, it combines picogram-level sensitivity with minimal sample requirements (25–50 µL), making it ideal for both pre-clinical and clinical research studies. --- > The rabbit polyclonal anti-normetanephrine antibody IS1028 was validated for immunohistofluorescence (IF) in crayfish tissues and mouse brain whole mounts using the STAINperfect immunostaining kit A. In combination with this kit, IS1028 can also enable effective visualization of normetanephrine in cell cultures and tissue sections. - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/normetanephrine-antibody-rabbit-pab/ - SKU: IS1028 - Price: 449.00 EUR Valided for IF in ganglia & midbrain tissues The rabbit polyclonal anti-normetanephrine antibody IS1028 was validated for immunohistofluorescence (IF) in crayfish tissues and mouse brain whole mounts using the STAINperfect immunostaining kit A. In combination with this kit, IS1028 can also enable effective visualization of normetanephrine in cell cultures and tissue sections. --- > The two kits included in the pack are optimized for the quantitation of Kynurenic Acid (KYNA) and Quinolinic Acid (QA) within serum and plasma samples. Working with a 25-50µL sample volume, these assays enable pre-clinical and clinical sample testing. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/kynureninic-acid-quinolinic-acid-elisa-pack/ - SKU: ISE-0102R - Price: 1,049.00 EUR High Sensitivity. Plasma, Serum. Min. Vol. 25-50µL. Cited in literature Immusmol’s two ready‑to‑use ELISA kits enable the quantification of kynurenic acid (KYNA) and quinolinic acid (QA) in serum or plasma. Requiring only a minimal sample volume (50µL) and compatible with any species, the assays fit seamlessly into both pre‑clinical and clinical workflows. These kits have already helped researchers investigate neuroinflammatory disorders such as bipolar disorder and multiple sclerosis in human plasma and serum samples. --- > The anti-L-Tyrosine antibody IS1037 was validated for immunofluorescence (IF) in mouse midbrain tissues in combination with the STAINperfect immunostaining kit A. Combined with this staining kit, this rabbit polyclonal antibody allows direct L-Tyrosine visualization in cell cultures, whole mounts, tissue sections. - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-tyrosine-antibody-rabbit-pab/ - SKU: IS1037 - Price: 449.00 EUR Validated for IF in mouse midbrain tissues The anti-L-Tyrosine antibody IS1037 was validated for immunofluorescence (IF) in mouse midbrain tissues in combination with the STAINperfect immunostaining kit A. Combined with this staining kit, this rabbit polyclonal antibody allows direct L-Tyrosine visualization in cell cultures, whole mounts, tissue sections. --- > Our team validated the rabbit polyclonal anti-L-phenylalanine antibody IS1038 for immunofluorescence (IF) in mouse midbrain tissues using the STAINperfect immunostaining kit A, demonstrating specific and accurate labeling of L-phenylalanine. - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-phenylalanine-antibody-rabbit-pab/ - SKU: IS1038 - Price: 449.00 EUR Validated for IF in mouse brain tissues Our team validated the rabbit polyclonal anti-L-phenylalanine antibody IS1038 for immunofluorescence (IF) in mouse midbrain tissues using the STAINperfect immunostaining kit A, demonstrating specific and accurate labeling of L-phenylalanine. --- > This rabbit polyclonal antibody recognizes L-Homoarginine at a 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors such as Asymetric DiMethyl Arginine (ADMA), Symetric DiMethyl Arginine (SDMA) and L-Arginine. Used with the STAINperfect immunostaining kit A, this antibody could allow direct L-Homoarginine visualization in cell culture and tissue samples (IF or IHC). - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-homoarginine-antibody-pab/ - SKU: IS1025 - Price: 449.00 EUR High Specificity & Affinity I IF / IHC / ICC This rabbit polyclonal antibody recognizes L-Homoarginine at a 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors such as Asymetric DiMethyl Arginine (ADMA), Symetric DiMethyl Arginine (SDMA) and L-Arginine. Used with the STAINperfect immunostaining kit A, this antibody could allow direct L-Homoarginine visualization in cell culture and tissue samples (IF or IHC). --- > Validated by direct and competitive ELISA, this rabbit polyclonal antibody recognizes L-Arginine at 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors such as L-Ornithine, L-Glutamate and L-Homoarginine. Our team is currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-arginine-antibody-pab/ - SKU: IS1055 - Price: 449.00 EUR High Specificity & Affinity. IF / IHC / ICC Validated by direct and competitive ELISA, this rabbit polyclonal antibody recognizes L-Arginine at 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors such as L-Ornithine, L-Glutamate and L-Homoarginine. Our team is currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. --- > The anti-GABA antibody IS1006 has been validated by our team for immunofluorescence in primary mouse and rat neurons using the STAINperfect immunostaining kit A. Additionally, recent scientific studies have employed this antibody to highlight GABAergic systems in human stem cell-derived neurons and rabbit olfactory bulb tissues. When combined with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody enables the clear visualization of gamma-aminobutyric acid (GABA) in cell cultures, tissue sections, and whole mounts from any species. - Published: 2022-02-11 - Modified: 2025-07-08 - URL: https://www.immusmol.com/product/gaba-antibody-rabbit-pab/ - SKU: IS1006 - Price: 449.00 EUR Used for IF in primary & iPSC-derived neurons, and brain tissues. Cited in literature The anti-GABA antibody IS1006 has been validated by our team for immunofluorescence in primary mouse and rat neurons using the STAINperfect immunostaining kit A. Additionally, recent scientific studies have employed this antibody to highlight GABAergic systems in human stem cell-derived neurons and rabbit olfactory bulb tissues. When combined with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody enables the clear visualization of gamma-aminobutyric acid (GABA) in cell cultures, tissue sections, and whole mounts from any species. --- > This anti-L-Ornithine antibody recognizes its target at a 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors such as L-Glutamine, L-Glutamate and L-Arginine. Our team is currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-ornithine-antibody-pab/ - SKU: IS1059 - Price: 449.00 EUR High specificity & affinity, IF / IHC / ICC This anti-L-Ornithine antibody recognizes its target at a 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors such as L-Glutamine, L-Glutamate and L-Arginine. Our team is currently working on the IF/ICC/IHC protocol for optimal staining in combination with the STAINperfect immunostaining kit A. --- > The anti-Serotonin antibody IS1007 allows for accturate labeling of 5-HT in cell cultures, tissue sections, and whole mounts prepared with the STAINperfect immunostaining kit A. Our team has validated this anti-5-HT antibody for immunofluorescence applications in crayfish tissues (whole mounts) as well as in mouse primary neurons and brain tissues (both tissue sections and whole mounts). - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/serotonin-antibody-rabbit-pab/ - SKU: IS1007 - Price: 449.00 EUR Validated for IF in primary neurons & brain tissues The anti-Serotonin antibody IS1007 allows for accturate labeling of 5-HT in cell cultures, tissue sections, and whole mounts prepared with the STAINperfect immunostaining kit A. Our team has validated this anti-5-HT antibody for immunofluorescence applications in crayfish tissues (whole mounts) as well as in mouse primary neurons and brain tissues (both tissue sections and whole mounts). --- > The anti-L-Glutamate antibody IS1001 has been validated for immunofluorescence applications in rodent primary neurons, mouse brain tissues, and crayfish brain tissues, in combination with the STAINperfect immunostaining kit A. Recent publications have leveraged this antibody to effectively stain glutamatergic systems in both mouse tissues and primary neurons. - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-glutamate-antibody-rabbit-polyclonal/ - SKU: IS1001 - Price: 449.00 EUR Validated for IF in primary neurons & brain tissues. Cited in literature The anti-L-Glutamate antibody IS1001 has been validated for immunofluorescence applications in rodent primary neurons, mouse brain tissues, and crayfish brain tissues, in combination with the STAINperfect immunostaining kit A. Recent publications have leveraged this antibody to effectively stain glutamatergic systems in both mouse tissues and primary neurons. --- > This rabbit polyclonal antibody recognizes L-Glutamine at a 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors. Using the STAINperfect immunostaining kit A, this primary antibody was used to visualize Glutamine in midbrain organoids (IF) and human tumor tissues (IHC). - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-glutamine-antibody-pab/ - SKU: IS1060 - Price: 449.00 EUR Validated for IF & IHC in human organoids and tumor specimens, cited in 2 papers This rabbit polyclonal antibody recognizes L-Glutamine at a 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors. Using the STAINperfect immunostaining kit A, this primary antibody was used to visualize Glutamine in midbrain organoids (IF) and human tumor tissues (IHC). --- > Anti-L-Glutamate antibody IS018 is a mouse monoclonal Ab used for IF in mouse primary neurons & human iPSC-derived neurons (2019 paper). Combined with the STAINperfect immunostaining kit A, this antibody accurately labels L-GLutamic acid in whole mounts, cell culture and tissue sections. - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-glutamate-antibody-mouse-mab/ - SKU: IS018 - Price: 449.00 EUR Validated for IF in primary neurons & iPSC-derived neurons. Cited in literature The anti-L-Glutamate antibody IS018 was validated in mouse primary neurons in combination with the STAINperfect immunostaining kit A. A recent paper also used this mouse monoclonal antibody to stain for L-Glutamate in human iPS-derived neurons. --- > Validated by direct and competitive ELISA, this rabbit polyclonal antibody recognizes L-Asparagine at 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors such as L-Glutamine and L-Aspartate. Combined with the STAINperfect immunostaining kit A, this antibody allows direct L-Asparagine imaging in various types of samples (cell cultures, tissue sections, whole mounts). - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-asparagine-antibody-pab/ - SKU: IS1056 - Price: 449.00 EUR High affinity & specificity, IF / IHC / ICC Validated by direct and competitive ELISA, this rabbit polyclonal antibody recognizes L-Asparagine at 1/10 000 working dilution, while displaying no significant cross-reactivity with competitors such as L-Glutamine and L-Aspartate. Combined with the STAINperfect immunostaining kit A, this antibody allows direct L-Asparagine imaging in various types of samples (cell cultures, tissue sections, whole mounts). --- > IS1002 is the only anti-D-Glutamate antibody available to date. This primary rabbit polyclonal antibody allows to stain for D-glutamic acid in cell cultures, whole mounts and tissue section when used in combination with the STAINperfect immunostaining kit A. Our team validated this antibody in mouse primary cortical neurons. - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/d-glutamate-antibody/ - SKU: IS1002 - Price: 449.00 EUR Only anti-D-glutamate antibody, Validated for IF in mouse primary neurons. IS1002 is the only anti-D-Glutamate antibody available to date. This primary rabbit polyclonal antibody allows to stain for D-glutamic acid in cell cultures, whole mounts and tissue section when used in combination with the STAINperfect immunostaining kit A. Our team validated this antibody in mouse primary cortical neurons. --- > The anti-D-Serine antibody IS1004 is the first and only antibody validated for immunofluorescence (IF) applications to date. When paired with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody enables clear visualization of D-Serine in cell cultures, tissue sections, and whole mounts. Our team successfully used IS1004 to detect D-Serine in mouse brain tissue sections. - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/d-serine-antibody/ - SKU: IS1004 - Price: 449.00 EUR First and only D-Serine antibody validated for IF (brain tissues) The anti-D-Serine antibody IS1004 is the first and only antibody validated for immunofluorescence (IF) applications to date. When paired with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody enables clear visualization of D-Serine in cell cultures, tissue sections, and whole mounts. Our team successfully used IS1004 to detect D-Serine in mouse brain tissue sections. --- > The anti-L-Serine antibody IS1003 is the first and only antibody available specifically for L-Serine detection. When paired with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody enables clear visualization of L-Serine in cell cultures, tissue sections, and whole mounts. Our team successfully employed IS1003 to detect L-Serine in mouse primary neurons and brainstem tissues. - Published: 2022-02-11 - Modified: 2025-06-26 - URL: https://www.immusmol.com/product/l-serine-antibody/ - SKU: IS1003 - Price: 449.00 EUR First & only L-Serine Antibody, validated for IF in primary neurons & brain tissues The anti-L-Serine antibody IS1003 is the first and only antibody available specifically for L-Serine detection. When paired with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody enables clear visualization of L-Serine in cell cultures, tissue sections, and whole mounts. Our team successfully employed IS1003 to detect L-Serine in mouse primary neurons and brainstem tissues. --- > This ELISA kit enables the quantitative measurement of L-Tryptophan in biological fluids and cell culture supernatants. Intended for in vitro diagnotics and research applications, the test comes in 96-well plate format, allowing the screening of large experimental series within short lead times. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/l-tryptophan-elisa-kit/ - SKU: BA-E-2700 - Price: 599.00 EUR High sensitivity, biological fluids (≥ 20µL), cited in 50+ papers The L-Tryptophan ELISA kit offers a robust and sensitive method for the quantitative measurement of L-Tryptophan in biological fluids and cell culture supernatants. Designed for both in vitro diagnostic and research applications, the assay is formatted on a 96-well plate — ideal for the rapid processing of large sample cohorts. This assay enables precise quantification from minimal sample volumes (as low as 20 µL) and has been cross-validated by LC-MS, ensuring excellent analytical performance. Applicable to all species, the kit has been successfully used in peer-reviewed studies involving human, monkey, dog, pig, mouse, rat, rabbit, and insect samples. Whether in basic research, preclinical development, or clinical investigations, this ELISA provides a reliable tool for studying tryptophan metabolism. --- > HomoArginine (hArg) ELISA kit for the determination of hArg in serum and plasma samples working with a minimal sample volume of 20μL. Easy to implement and well-suited for both preclinical and clinical studies. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/homoarginine-elisa-kit/ - SKU: IS-I-0500R - Price: 599.00 EUR High Sensitivity, Plasma & Serum (≥ 20µL), Cited in literature The HomoArginine (hArg) ELISA kit enables sensitive and quantitative measurement of the non-essential amino acid HomoArginine in serum and plasma samples. Validated in human plasma with strong concordance to LC-MS results, this user-friendly assay provides robust performance across a range of study designs. Species-independent and requiring only 20 µL of sample, it is ideally suited for both preclinical and clinical research applications. --- > Dopamine ELISA kit for the rapid measurement of Dopamine (DA) in urine and plasma. samples. 40 samples within 4 hours. Cited in 7 papers - Published: 2022-02-11 - Modified: 2025-06-30 - URL: https://www.immusmol.com/product/dopamine-elisa-kit-urine-plasma-samples/ - SKU: BA-E-6300 - Price: 499.00 EUR Fast (4h), Research or In Vitro Diagnostics applications This Dopamine ELISA kit is tailored for the rapid measurement of Dopamine (DA) in urine and plasma samples. Intended for in vitro diagnostics and research use, this fast-track quantitative immunoassay enables to determine dopamine levels in up to 40 samples within 4 hours. --- > Achieve high-quality stainings with 30+ antibodies to neurotransmitters, amino-acids, & their metabolites. Cited in 20+ papers. Validated in rodent & human specimens. - Published: 2022-02-11 - Modified: 2025-07-28 - URL: https://www.immusmol.com/product/stainperfect-immunostaining-kit-a/ - SKU: SP-A-1000 - Price: 299.00 EUR Compatible with 30+ antibodies. Cell culture/Whole mounts/Tissue sections. Cited in 20+ papers The STAINperfect™ immunostaining kit A provides all necessary reagents and protocols to achieve high-quality stainings with Immusmol’s antibodies. The kit can be combined with over 30 antibodies targeting key neurotransmitters, amino acids, and their downstream metabolites. See compatible antibodies below. --- > This research Dopamine ELISA kit enables the ultra-sensitive measurement of Dopamine (DA) in any biological sample. 1 µl min. sample volume. - Published: 2022-02-11 - Modified: 2025-07-29 - URL: https://www.immusmol.com/product/dopamine-elisa-kit-any-sample/ - SKU: BA-E-5300R - Price: 599.00 EUR Ultra-sensitive, ≥ 1µl sample, Cited in 30+ papers This research Dopamine ELISA kit enables the ultra-sensitive measurement of Dopamine (DA) in any biological sample, from any species. Cross-validated by LC-MS, highly flexible, this dopamine assay features a minimal sample volume as low as 1 µL, with a limit of detection at 3. 3 pg/mL. --- > The Arginine (Arg) ELISA kit for the determination of Arg in serum, plasma, and supernatants, working with a sample volume of 20μL. Easy to implement and well-suited for both preclinical and clinical studies. - Published: 2022-02-11 - Modified: 2025-07-28 - URL: https://www.immusmol.com/product/arginine-elisa-kit/ - SKU: IS-I-0400R - Price: 599.00 EUR High Sensitivity, Plasma, Serum, Supernatant (≥ 20µL), Cited in 3 papers The Arginine (L-Arg) ELISA kit enables the quantitative determination of the non-essential amino acid L-Arginine in serum, plasma, and cell culture supernatants. Validated in human plasma with a high correlation to LC-MS results, the assay has also been successfully applied to mouse serum samples (see supporting data). Designed for versatility, the kit is species-independent and requires only a small sample volume (20 µL), making it well-suited for both preclinical research and clinical studies. --- > This GABA ELISA kit enables the measurement of Gamma-aminobutyric acid in any biological sample. Intended for in vitro diagnostics, this quantitative assay can be performed in cell cultures, tissue homogenates, urine, plasma, serum, etc. - Published: 2022-02-11 - Modified: 2025-07-24 - URL: https://www.immusmol.com/product/gaba-elisa-kit-any-sample/ - SKU: BA-E-2500 - Price: 599.00 EUR in vitro Diagnostics (EU only) or Research use, Cited in 12 papers This GABA ELISA kit enables the measurement of Gamma-aminobutyric acid in any biological sample. Intended for in vitro diagnostics, this quantitative assay can be performed in cell cultures, tissue homogenates, urine, plasma, serum, etc. --- > Our anti-L-Kynurenine antibody IS1003 enabled to illustrate, for the first time, the presence of L-kynurenine in human brain and tumor samples by IHC and IF. In the literature, the antibody was used to stain for kynurenine in mouse tissues (tumor, brain, heart) and human samples (cell culture, atheroma plaque, and tumor specimens). This mouse monoclonal antibody can be used in combination with other primary antibodies to kynurenine metabolites (rabbit polyclonals available). - Published: 2022-02-11 - Modified: 2025-07-23 - URL: https://www.immusmol.com/product/l-kynurenine-mab/ - SKU: IS003 - Price: 449.00 EUR Used for IF & IHC in brain, heart, and tumor tissues I Cited in 10+ papers Our anti-L-Kynurenine antibody IS1003 enabled to illustrate, for the first time, the presence of L-kynurenine in human brain and tumor samples by IHC and IF. In the literature, the antibody was used to stain for kynurenine in mouse tissues (tumor, brain, heart) and human samples (cell culture, atheroma plaque, and tumor specimens). This mouse monoclonal antibody can be used in combination with other primary antibodies to kynurenine metabolites (rabbit polyclonals available). --- > The rabbit polyclonal anti-L-kynurenine antibody IS1012 was validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) human tumor tissues at a 1:500 dilution. Recently, this antibody was successfully used in two studies to stain macaque immune cells and human FFPE lung tissues for L-kynurenine. - Published: 2022-02-11 - Modified: 2025-07-09 - URL: https://www.immusmol.com/product/l-kynurenine-pab/ - SKU: IS1012 - Price: 449.00 EUR Used for IHC in FFPE lung & tumor tissues. Cited in literature The rabbit polyclonal anti-L-kynurenine antibody IS1012 was validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) human tumor tissues at a 1:500 dilution. Recently, this antibody was successfully used in two studies to stain macaque immune cells and human FFPE lung tissues for L-kynurenine. --- > The monoclonal IS010 anti-Kynurenic acid (KYNA) antibody was validated for IHC and IF in human caudate putamen tissues. Cited in literature. Highly affine and specific mAb. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/kynurenic-acid-mab/ - SKU: IS010 - Price: 449.00 EUR Used for IHC/IF in FFPE brain tissues. Cited in literature The monoclonal IS010 anti-Kynurenic acid antibody was validated for IHC and IF in human caudate putamen tissues. Competitive ELISA demonstrated the antibody to be highly affine and specific. --- > The monoclonal anti-Anthranilic acid antibody 10G1-F1 was validated for immunohistochemistry (IHC) in human brain tissues. Highly specific, as demonstrated by competitive ELISA, the antibody consistently delivered clean and reproducible stainings. - Published: 2022-02-11 - Modified: 2025-06-23 - URL: https://www.immusmol.com/product/anthranilic-acid-antibody-mab/ - SKU: IS013 - Price: 449.00 EUR Validated for IHC in FFPE brain tissues The monoclonal anti-Anthranilic acid antibody 10G1-F1 was validated for immunohistochemistry (IHC) in human brain tissues. Highly specific, as demonstrated by competitive ELISA, the antibody consistently delivered clean and reproducible stainings --- > In vitro diagnostics & research enzyme immunoassay (ELISA) for the quantitative determination of histamine levels in urine and plasma samples. The immunoassay can be combined with the add-on kit BA-E-1100, to quantify histamine release in whole blood. - Published: 2022-02-11 - Modified: 2025-06-25 - URL: https://www.immusmol.com/product/histamine-elisa-kit-urine-plasma-samples/ - SKU: BA-E-1000 - Price: 399.00 EUR High sensitivity, Fast (5h), Cited in 2 papers This Histamine ELISA kit is tailored for the quantitative measurement of histamine in urine and plasma samples. Intended for in vitro diagnostics or research use, the immunoassay can be combined with the add-on kit BA-E-1100, to quantify histamine release in whole blood. --- --- ## Landing Pages ---