Kynurenine/Tryptophan ratio ELISA pack

Ref: ISE-2227R
Kynurenine pathwayTryptophan metabolismResearch ELISA kits (RUO)ELISA
DatasheetMSDS TryptophanProtocol TryptophanMSDS KynurenineProtocol Kynurenine

The Kynurenine/Tryptophan ratio ELISA pack enables quantitative measurements of tryptophan catabolism along the kynurenine pathway in large numbers of samples. Intended for research use only, the two kits included in the pack are ready to use. Highly sensitive, with a minimum sample volume of 20µl, they permit the performance of longitudinal studies in mice.

Sample type Plasma, Serum, Cell culture supernatant, (Urine)
Kit capacity 2 x 96 tests
Sensitivity LoD KYN: < 47.5ng/ml
LoD TRP: < 1.2µg/ml
Range KYN: 0/100 – 10000ng/ml
TRP: 2.5 – 250µg/ml
Reactivity Reacts with all species
References Citations in literature

2 x 96 wells


96 in stock



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Product overview

Product name Kynurenine/Tryptophan ratio ELISA pack
Description Two enzyme immunoassays (ELISA) allowing the quantitative determination of L-Kynurenine to L-Tryptophan ratio in urine, plasma and serum samples. For research use only
Labels RUO
Format 2 x 96-well plate
Samples Plasma, serum, cell culture supernatant, (Urine)
Minimum sample volume 20µL
Reactivity Reacts with all species
Standard range KYN: 0/100 – 10000ng/ml
TRP: 2.5 – 250µg/ml

LoD KYN: < 47.5ng/ml
LoD TRP: < 1.2µg/ml

Specificity No significant cross-reactivity was observed with L-Tryptophan and L-Kynurenine analogs. See product pages for L-Kynurenine ELISA and L-Tryptophan ELISA
Storage Store at 2-8°C for to 6 months
Datasheets Instructions for use – TRP kit, Instructions for use -KYN kit


The pack for in-vitro-diagnostic (IVD) use  can be ordered with the catalogue no. ISE-2227

Sample collection & storage Plasma/Serum: EDTA-, Heparin- or Citrate- samples stored at 2-8°C for up to 48h or -20°C for longer period (up to 6 months)
Sample preparation KYN: Sample acylation (90 min)
TRP: Sample precipitation (15 min) and derivatization (2h)
ELISA Antisera overnight incubation, revelation and read steps (1h)
Detailed protocol Instructions for use – TRP kit, Instructions for use – KYN kit

Product citations :

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