Cinnabarinic acid Monoclonal Antobidy

Ref: IS005
Kynurenine pathwayMonoclonal AntibodiesICCIFIHC
DatasheetMSDS

The first and only validated anti-Cinnabarinic acid antibody available for research use. IHC validation of the 5C5-E10 mAb in human brain and breast tumor tissues revealed the presence, in specific cells, of Cinnabarinic acid, a tryptophan metabolite known for its immunomodulatory role.

Clonality Monoclonal antibody (clone 5C5-E10)
Host Mouse
Valided applications IHC
Reactivity Reacts with all species
References Not yet cited to our knowledge
Submit content and get a 10% discount!
Format 50µL

 

Size

50µl

440.00

100 in stock

Quantity
Total

440.00

Worldwide shipping

Select delivery location

Product overview

Product name Cinnabarinic acid antibody
Synonyms 2-amino- 3-oxo- 3H-phenoxazine-1,9-dicarboxylic acid antibody
Immunogen Conjugated Cinnabarinic acid
Isotype IgG1 k chain
Clone clone 5C5-E10
Specificity When tested in competitive ELISA, the anti-Cinnabarinic acid antibody 5C5-E10 did not cross-react with its precursor, 3-OH-Anthranilic acid conjugates

Storage

Form Liquid
Purity Purified IgG
Concentration 0,5mg/ml
Storage
Store at +4°C for short term (1-2 months). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles
Material safety datasheet Download MSDS

Immunohistochemistry (IHC) Dilute at 1:200-1:2000. Perform heat antigen retrieval (pH=6) before initiating IHC staining protocol on paraffin-embedded and frozen sections
Immunofluorescence (IF) Dilute at 1:100-1:1000 on paraffin-embedded and frozen sections. Perform heat antigen retrieval and incubate with fluorescent secondary antibody conjugate
Comments Optimal working dilutions must be determined by the end-user
Restrictions For research use only

Product citation

  • The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia
    Check the article
    Authors : Ulivieri et al., Schizophrenia Bulletin
    2020-12

You may also like…

3-HydroxyAnthranilic acid Monoclonal Antibody

IS001

Reactivity: All species
Validated applications: IHC
Host: Mouse

440.00
VIEW PRODUCTADD

Kynurenines IHC/IF Starter Pack

KY-ABSP

Special pack to test our Monoclonal and Polyclonal Antibodies against kynurenine pathway metabolites.

3-Hydroxyanthranilic Polyclonal Antibody

IS1008

Reactivity: All species
Validated applications: IHC, IF
Host: Rabbit

440.00
VIEW PRODUCTADD

L-Kynurenine Monoclonal Antibody

IS003

Reactivity: All species
Validated applications: IHC, IF
Host: Mouse

440.00
VIEW PRODUCTADD