Cinnabarinic acid Antibody – Mouse Monoclonal

Ref: IS005
Kynurenine pathwayTryptophan metabolismMonoclonal AntibodiesICCIFIHC
DatasheetMSDS

The first and only validated anti-Cinnabarinic acid antibody available for research use. IHC validation of this mouse mAb in human brain and breast tumor tissues revealed the presence, in specific cells, of Cinnabarinic acid, a tryptophan metabolite known for its immunomodulatory role. A 2020 paper also used this anti-cinnabarinic antibody to stain mouse brain tissue sections (immunofluorescence).

ClonalityMonoclonal antibody (clone 5C5-E10)
HostMouse
Valided applicationsIHC & IF
ReactivityReacts with all species
Format50µL
ReferencesCited in 1 paper

 

Size

50µl

440.00

98 in stock

Quantity
Total

440.00

Worldwide shipping

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Product overview

Product nameCinnabarinic acid antibody
Synonyms2-amino- 3-oxo- 3H-phenoxazine-1,9-dicarboxylic acid antibody
ImmunogenConjugated Cinnabarinic acid
IsotypeIgG1 k chain
Cloneclone 5C5-E10
SpecificityWhen tested in competitive ELISA, the anti-Cinnabarinic acid antibody 5C5-E10 did not cross-react with its precursor, 3-OH-Anthranilic acid conjugates
Lot Number140201
Expiration date2026-01-01

Storage

FormLiquid
PurityPurified IgG
Concentration0,5mg/ml
Storage
Store at +4°C for short term (6 months). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles
Material safety datasheetDownload MSDS

Immunohistochemistry (IHC)Dilute at 1:200-1:2000. Perform heat antigen retrieval (pH=6) before initiating IHC staining protocol on paraffin-embedded and frozen sections
Immunofluorescence (IF)Dilute at 1:100-1:1000 on paraffin-embedded and frozen sections. Perform heat antigen retrieval and incubate with fluorescent secondary antibody conjugate
CommentsOptimal working dilutions must be determined by the end-user
RestrictionsFor research use only

Product citation

  • The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia
    Check the article
    Authors : Ulivieri et al., Schizophrenia Bulletin
    2020-12

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