Assessing the polyamine pathway through immunoassays!
capable of detecting amino acids, saccharides, neurotransmitters and neuromediators, lipids, toxins… and drugs!
Through our range of ELISA kits and immunoglobulins, Immusmol open the way of low molecular weight entities for new set of possibilities in research, diagnostic and therapy.
Standard range: 3.8 – 625µM
LoD: 13µM (2.4µg/mL)
Standard range: 16 – 650µM (3 – 118µg/mL)
Our catalog only features validated small molecule antibodies & ELISA kits. Selected for their specificity and affinity by ELISA, our antibodies enable rapid & robust detection and/or quantification of small molecules in various types of biological materials, including cells and lysates, tissues and homogenates, culture supernatants, plasma and serum samples.
Given the importance of the polyamine pathway in cancer progression and resistance to treatment, investigating it requires robust tools. To this aim, we developed and validated the first ELISA kits to quantify ornithine, N1-acetylspermidine, and N8-acetylspermidine in samples of different natures (plasma, cell culture supernatants) and different species (mouse, human).
Benefit from our current special offer on a range of specific and highly sensitive ELISA kits to obtain valuable quantitative data on monoamine levels in various fluids, including blood and urine.
Serotonin (5-HT) is one of the most potent monoamine neurotransmitters and peripheral signaling molecules. Physiologically, 5-HT has complex and diverse effects on the central and peripheral nervous systems, neuroendocrine regulation, and immunological responses. We recently developed and added to our catalog a novel antibody raised against 5-HT, compatible with formalin-fixed biological materials.
Given the importance of the Arginase pathway in pathophysiological processes, we have developed and validated a robust and easy-to-use immunoassay for the simultaneous detection and quantification of both L-Arginine and L-Ornithine in plasma / serum.
Among mechanisms associated with cancer immune evasion, the activation of the Kynurenine Pathway (KP) is known to play a key role and has thus been proposed as a therapeutic target to improve current immune checkpoint blockade-based immunotherapies.
2023 is near, but there’s still time to check out our best highlights of the second half of 2022! Stay connected, great things are coming next year!
L-Arginine is a key amino acid in the immune regulation and can be targeted as part of an anti-tumor response. We have thus developed and validated an ELISA kit for the detection and quatification of L-Arginine in biological samples.
Don’t miss this offer! Take a tour of our product webpage to select your favorites and benefit from this season’s offer to try them!