L-Serine Polyclonal AntibodyRef: IS1003
The rabbit polyclonal antibody directed against conjugated L-Serine IS1003 is highly affine and specific. In combination with the STAINperfect immunostaining kit A, the antibody directly labels L-serine in whole mounts, cell culture and tissue sections.
|Reactivity||Reacts with all species|
|Tested samples||Whole mounts, cell culture, tissue sections|
|Staining procedure||STAINperfect immunostaining kit A|
|Format||50µL (approx. 40 tissue sections)|
|Product name||L-Serine antibody – Rabbit pAb|
|Synonyms||Anti-L-Serine acid antibody
Anti-(S)-2-amino-3-hydroxypropionic acid antibody
|Specificity||When tested in competitive ELISA, the anti-conjugated L-Serine antibody did not show any significant cross reactivity with L-Serine analogs, including D-Serine and L-Threonine conjugates|
|Storage buffer||Store at +4°C for short term (1-2 monts). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles|
|Material safety datasheet||Download MSDS|
|IF – Cell cultures, Whole mounts, Tissue sections||Dilute antibody with the antibody diluent provided in the STAINperfect immunostaining kit A. Use at 1/250 -1/1000 dilution. Follow the STAINperfect protocol suited to your sample|
|Comments||Optimal working dilutions must be determined by the end-user|
|Restrictions||For research use only|
|Full protocol||Download STAINperfect protocol for L-Serine staining|
Instructions for Use
for cell cultures
for whole mounts
for tissue sections
Antibody not yet cited. Submit an article and get a 10% discount.
Selected publications about L-Serine:
- Pollari S et al. Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis. Breast Cancer Res Treat. 2011 Jan;125(2):421-30. doi: 10.1007/s10549-010-0848-5. Epub 2010 Mar 30.
- Yang JH et al. Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of D-serine, an N-methyl-D-aspartate receptor co-agonist, in adult brain. J Biol Chem. 2010 Dec 31;285(53):41380-90. doi: 10.1074/jbc.M110.187443. Epub 2010 Oct 21.
- Tabatabaie L, Klomp LW, Berger R, de Koning TJ. L-serine synthesis in the central nervous system: a review on serine deficiency disorders. Mol Genet Metab. 2010 Mar;99(3):256-62. doi: 10.1016/j.ymgme.2009.10.012. Epub 2009 Oct 25.