Quinolinic Acid ELISA kit
High Sensitivity, Plasma & Serum

Ref: IS-I-0100R
ELISAKynurenine pathwayTryptophan metabolismToxinsResearch ELISA kits (RUO)
DatasheetMSDSProtocol

Quinolinic acid (QA) is a metabolite produced along the Kynurenine Pathway, which converts the aminoacid Tryptophan to NAD+, a co-factor of many enzymatic reactions.

The Quinolinic Acid ELISA kit is optimized for the quantitation of Quinolinic Acid (QUIN or QA) within serum and plasma samples. This easy-to-use competitive assay is well-suited for both small and large series of samples. Working with a low sample volume of 25µL, this assay enables pre-clinical and clinical sample testings.

Sample type Serum, Plasma
Capacity 96 tests
Sensitivity 35.9nM
Range 150 – 12150nM
Assay time Sample acylation 120 min, ELISA overnight
Reactivity Reacts with all species
References Cited in 7 papers
Size

1 x 96 wells

539.00

14 in stock

Quantity
Total

539.00

Worldwide shipping

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Product overview

Product name Quinolinic Acid ELISA kit
Description Competitive ELISA kit for the quantitative measurement of Quinolinic Acid levels in serum and plasma samples. For research use only
Format 96-well plate
Samples Serum, Plasma
Minimal sample volume 25µL
Reactivity Reacts with all species
Standard range 25 – 2000ng/mL
Sensitivity

< 6ng/mL

Specificity No significant cross-reactivity was observed with Quinolinic Acid analogs such as Kynurenic acid, Xanthurenic acid, Kynurenine, Picolinic acid, 3-Hydroxy-Anthranilic Acid
Assay time Sample acylation 120 min and ELISA overnight
Storage Store at 2-8°C for up to 6 months
Datasheets Instructions for useMaterial Safety Datasheet

Sample collection & storage Serum: Do not use lipemic, haemolytic samples, as well as samples containing precipitates or fibrin strands

Plasma (Heparin)

Store samples at 2-8°C for up to 48h or -20°C for longer period (up to 6 months)

Sample preparation Sample acylation (120 min)
ELISA Quinolinic acid antiserum overnight incubation, revelation and read steps (1h)
Detailed protocol Download instructions for use

Product citations

  • Advances in kynurenine analysis
    Check the article
    Authors : Mrstna et al., Clinica Chimica Acta
    2023-07
  • Atheroma plaque microenvironment stimulates kynurenine production by macrophages to induce endothelial adhesion molecules in the context of atherogenesis
    Check the article
    Authors : Dongen et al., bioRxiv
    2023-07
  • Unlocking the Secrets: Exploring the Biochemical Correlates of Suicidal Thoughts and Behaviors in Adults with Autism Spectrum Conditions
    Check the article
    Authors : Cremone et al., Biomedicines
    2023-04
  • Nociceptor-derived Reg3g prevents endotoxic death by targeting kynurenine pathway in microglia
    Check the article
    Authors : Sugisawa et al., Cell reports
    2022-03
  • Apathy is not associated with a panel of biomarkers in older adults with HIV disease
    Check the article
    Authors : Wood et al., Journal of psychosomatic research
    2021-11
  • Electrochemical Determination of Kynurenine Pathway Metabolites—Challenges and Perspectives
    Check the article
    Authors : Sadok et al., Sensors
    2021-10
  • Synbiotic Supplementation Improves Obesity Index and Metabolic Biomarkers in Thai Obese Adults: A Randomized Clinical Trial
    Check the article
    Authors : Chaiyasut et al, Foods
    2021-07

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