Quinolinic Acid ELISA kit
High Sensitivity, Plasma & Serum

Ref: IS-I-0100R
ToxinsResearch ELISA kits (RUO)ELISAKynurenine pathwayTryptophan metabolism
DatasheetMSDSProtocol

Quinolinic acid (QA) is a metabolite produced along the Kynurenine Pathway, which converts the aminoacid Tryptophan to NAD+, a co-factor of many enzymatic reactions.

The Quinolinic Acid ELISA kit is optimized for the quantitation of Quinolinic Acid (QUIN or QA) within serum and plasma samples. This easy-to-use competitive assay is well-suited for both small and large series of samples. Working with a low sample volume of 25µL, this assay enables pre-clinical and clinical sample testings.

Sample typeSerum, Plasma
Capacity96 tests
Sensitivity35.9nM
Range150 – 12150nM
Assay timeSample acylation 120 min, ELISA overnight
ReactivityReacts with all species
ReferencesCited in 7 papers
Size

1 x 96 wells

539.00

18 in stock

Quantity
Total

539.00

Worldwide shipping

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Product overview

Product nameQuinolinic Acid ELISA kit
DescriptionCompetitive ELISA kit for the quantitative measurement of Quinolinic Acid levels in serum and plasma samples. For research use only
Format96-well plate
SamplesSerum, Plasma
Minimal sample volume25µL
ReactivityReacts with all species
Standard range25 – 2000ng/mL
Sensitivity

< 6ng/mL

SpecificityNo significant cross-reactivity was observed with Quinolinic Acid analogs such as Kynurenic acid, Xanthurenic acid, Kynurenine, Picolinic acid, 3-Hydroxy-Anthranilic Acid
Assay timeSample acylation 120 min and ELISA overnight
StorageStore at 2-8°C for up to 6 months
DatasheetsInstructions for useMaterial Safety Datasheet

Sample collection & storageSerum: Do not use lipemic, haemolytic samples, as well as samples containing precipitates or fibrin strands

Plasma (Heparin)

Store samples at 2-8°C for up to 48h or -20°C for longer period (up to 6 months)

Sample preparationSample acylation (120 min)
ELISAQuinolinic acid antiserum overnight incubation, revelation and read steps (1h)
Detailed protocolDownload instructions for use

Product citations

  • Advances in kynurenine analysis
    Check the article
    Authors : Mrstna et al., Clinica Chimica Acta
    2023-07
  • Atheroma plaque microenvironment stimulates kynurenine production by macrophages to induce endothelial adhesion molecules in the context of atherogenesis
    Check the article
    Authors : Dongen et al., bioRxiv
    2023-07
  • Unlocking the Secrets: Exploring the Biochemical Correlates of Suicidal Thoughts and Behaviors in Adults with Autism Spectrum Conditions
    Check the article
    Authors : Cremone et al., Biomedicines
    2023-04
  • Nociceptor-derived Reg3g prevents endotoxic death by targeting kynurenine pathway in microglia
    Check the article
    Authors : Sugisawa et al., Cell reports
    2022-03
  • Apathy is not associated with a panel of biomarkers in older adults with HIV disease
    Check the article
    Authors : Wood et al., Journal of psychosomatic research
    2021-11
  • Electrochemical Determination of Kynurenine Pathway Metabolites—Challenges and Perspectives
    Check the article
    Authors : Sadok et al., Sensors
    2021-10
  • Synbiotic Supplementation Improves Obesity Index and Metabolic Biomarkers in Thai Obese Adults: A Randomized Clinical Trial
    Check the article
    Authors : Chaiyasut et al, Foods
    2021-07

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