Quinolinic acid Antibody – Mouse Monoclonal

Ref: IS002
Kynurenine pathwayTryptophan metabolismToxinsMonoclonal AntibodiesICCIFIHC
DatasheetMSDS

This mouse monoclonal antibody to Quinolinic acid was validated for IF & IHC in human brain tissues. It was recently used in 3 papers to evidence the role of Quinolinic acid in atherogenesis & glioblastoma.

Clonality Monoclonal antibody (clone 4E11-G3)
Host Mouse
Valided applications IHC / IF
Reactivity Reacts with all species
References Not yet cited to our knowledge
Submit content and get a 10% discount!
Format 50µL
References Cited in 3 papers
Size

50µl

440.00

88 in stock

Quantity
Total

440.00

Worldwide shipping

Select delivery location

Product overview

Product name Quinolinic acid antibody
Synonyms Pyridine-2,3-dicarboxylic acid antibody

2,3-pyridinedicarboxylic acid antibody

3,4-Pyridinedicarboxylic acid antibody

Pyridine-3,4-dicarboxylic acid antibody

Immunogen Conjugated quinolinic acid
Isotype IgG1 k chain
Clone clone 4E11-G3
Specificity When tested in competitive ELISA, the anti-Quinolinic acid antibody did not show any significant cross reactivity with Picolinic and Quinaldic acid conjugates
Lot number 140201
Expiration date 2025-02-01

Storage

Form Liquid
Purity Purified IgG
Concentration 0,5mg/ml
Storage
Store at +4°C for short term (1-2 months). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles
Material safety datasheet Download MSDS

Immunohistochemistry (IHC) Dilute at 1:100-1:1000. Perform heat antigen retrieval (pH=9) before initiating IHC staining protocol on paraffin-embedded and frozen sections
Immunofluorescence (IF) Dilute at 1:50-1:500 on paraffin-embedded and frozen sections. Perform heat antigen retrieval and incubate fluorescent dyes conjugated secondary antibody
Comments Optimal working dilutions must be determined by the end-user
Restrictions For research use only

Product citation

  • Atheroma plaque microenvironment stimulates kynurenine production by macrophages to induce endothelial adhesion molecules in the context of atherogenesis
    Check the article
    Authors : Dongen et al., bioRxiv
    2023-07
  • Quinolinate promotes macrophage-induced immune tolerance in glioblastoma through the NMDAR/PPARγ signaling axis
    Check the article
    Authors : Kesarwani et al., Nature Communications
    2023-03
  • Nociceptor-derived Reg3g prevents endotoxic death by targeting kynurenine pathway in microglia
    Check the article
    Authors : Sugisawa et al., Cell reports
    2022-03

You may also like…

Kynurenic acid Antibody – Rabbit Polyclonal

IS1011

Used for IHC in paraffin-embedded human brain tissues

440.00
VIEW PRODUCTADD

Quinolinic acid Antibody – Rabbit Polyclonal

IS1010

Used for IHC in human brain & lung samples
Cited 1 paper

440.00
VIEW PRODUCTADD

L-Kynurenine Antibody – Mouse Monoclonal

IS003

Used for IF & IHC in mouse tissues & human brain, heart, & FFPE tumor tissues
Cited in 9 papers

440.00
VIEW PRODUCTADD

Quinolinic Acid ELISA kit
High Sensitivity, Plasma & Serum

IS-I-0100R

Use Research
Samples Plasma, Serum (25µl)
Feature High Sensitivity

539.00
VIEW PRODUCTADD