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Kynurenic acid ELISA kitKynurenic acid (KYNA) is a downstream metabolite of the kynurenine pathway with well‑established neuromodulatory and immunomodulatory properties. Quantifying KYNA in biological samples is increasingly explored as a biomarker strategy for numerous conditions, particularly neurological and psychiatric disorders.
Cross-validation_KYNA_Kynurenic-AcidHuman serum samples (n=40) were processed for Kynurenic Acid measurement by mean of both KYNA ELISA kit and liquid chromatography–mass spectrometry (LC/MS). As depicted, results obtained with ELISA and LC/MS are highly correlated (R Squared=0,9902).
Key features
| Sample type | Serum |
| Capacity | 96 tests |
| Sensitivity | 0.53ng/mL |
| Range | 1.40 – 74ng/mL |
| Assay time | Sample derivatization (90min), overnight incubation, ELISA revelation & read step (1h) |
| Reactivity | Reacts with all species |
| Application | Research use only |
Frequently asked questions
Kynurenic Acid ELISA kit
The Kynurenic Acid ELISA kit is optimized for sensitive quantification of kynurenic acid (KYNA) in serum. This competitive, user‑friendly assay is species‑independent and requires only 50 µL of sample, making it well-suited for research applications. Researchers have already applied it to human serum, plasma, and cell‑culture supernatants to investigate neuroinflammatory disorders—including Alzheimer’s disease, COVID‑19, multiple sclerosis, bipolar disorder, and autism spectrum disorder—as well as cancer.
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IS-I-0200R
Kynurenic Acid ELISA kit
Kynurenic acid ELISA kit – Research test for the detection of Kynurenic Acid
Specifications
| Product name | Kynurenic Acid ELISA kit |
| Description | Competitive ELISA kit for the quantitative measurement of Kynurenic Acid in serum samples. For research use only |
| Format | 96-well plate |
| Samples | Serum |
| Minimal sample volume | 50µL |
| Reactivity | Reacts with all species |
| Standard range | 1.40 – 74ng/mL |
| Sensitivity |
0.53ng/mL |
| Specificity | No significant cross-reactivity was observed with Kynurenic Acid analogs such as Quinolinic Acid, Xanthurenic acid, Kynurenine, Picolinic acid, 3-Hydroxy-Anthranilic Acid |
| Assay time | Sample derivatization (90min), overnight incubation, ELISA revelation & read step (1h) |
Instructions
| Storage | Store at 2-8°C for to 6 months |
| Sample collection & storage | Serum: Do not use lipemic, haemolytic samples, as well as samples containing precipitates or fibrin strands. Store samples at 2-8°C for up to 48h or -20°C for longer period (up to 6 months) |
| Sample preparation | Sample derivatization (90 min) |
| ELISA | Antisera overnight incubation, revelation, and read steps (1h) |
