Kynurenic acid Antibody – Mouse Monoclonal

Ref: IS010
Kynurenine pathwayMonoclonal AntibodiesICCIFIHC
DatasheetMSDS

The monoclonal IS010 anti-Kynurenic acid antibody was validated for IHC and IF in human caudate putamen tissues. Competitive ELISA demonstrated the antibody to be highly affine and specific.

Clonality Monoclonal antibody (clone 4G12-A12)
Host Mouse
Validated applications IHC / IF
Specie reactivity Reacts with all species
References Not yet cited to our knowledge.
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Format 50µL
References Cited in literature
Size

50µl

440.00

88 in stock

Quantity
Total

440.00

Worldwide shipping

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Product overview

Product name Kynurenic acid antibody
Synonyms Kinurenic acid antibody

4-Hydroxyquinoline-2-carboxylic acid antibody

KYNA antibody

Immunogen Conjugated kynurenic acid
Isotype IgG1 k chain
Clone clone 4G12-A12
Specificity When tested in competitive ELISA, the anti-Kynurenic antibody 4G12-A12 did not show any significant cross reactivity with Quinaldic, Xanthurenic, Anthranilic, Picolinic or Quinolinic acid conjugates

Storage

Form Liquid
Purity Purified IgG
Concentration 0,5mg/ml
Storage Store at +4°C for short term (1-2 months). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles
Material safety datasheet Download MSDS

Immunohistochemistry (IHC) Dilute at 1:200-1:2000. Perform heat antigen retrieval (pH=6) before initiating IHC staining protocol on paraffin-embedded and frozen sections
Immunofluorescence (IF) 1:100-1:1000 on paraffin-embedded and frozen sections. Before staining, perform heat antigen retrieval
Comments Optimal working dilutions must be determined by the end-user
Restrictions For research use only

Literature citations

  • Atheroma plaque microenvironment stimulates kynurenine production by macrophages to induce endothelial adhesion molecules in the context of atherogenesis
    Check the article
    Authors : Dongen et al., bioRxiv
    2023-07

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