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Custom development of small molecule monoclonal antibodies

Immusmol develops mouse monoclonal antibodies (mAbs) for small molecule detection (amino acid metabolites, lipids, saccharids, toxins, steroids, etc.) by IHC or ELISA. Highly reliable, small molecule mAbs are particularly suited to diagnostic & theranostic applications.

 

Advantages of small molecule monoclonal antibodies

  • High specificity & affinity – Internal selection protocols are implemented to ensure our mAbs translate into robust and accurate immunoassays.
  • Cross-species reactivity – Unlike proteins, small molecules are conserved throughout phylogenesis. A single small molecule mAb can thus be applied to virtually any biological sample.
  • High reproducibility & availability – Produced in vitro by a single immortalized cell clone, our monoclonal antibodies meet industrial standards for quality and scalability.

Our approach for the development of small molecule mAbs

  • A personalized strategy for antigen design, based on an in-depth analysis of the physico-chemical properties, immunogenicity and potential competitors of the small molecule target to address, tailored to your intended use of the antibody.
  • Quality controls, deliverables, Go/No-Go decision points at the end of each phase, to ensure transparent projects with limited risk and deferred costs.
  • Full ownership of the antibody-producing clone is granted to the client at the end of the study, together with at least 2mg of purified monoclonal immunoglobulin.

Additional options & services

To meet your specific needs, we can complement our standard mAb production process with additional services, such as:

  • Custom molecule synthesis
  • Antigen coupling validation by NMR
  • Measurement of antibody binding affinity by surface plasmon resonance (Biacore)
  • Complementary antibody production and purification
  • Antibody validation for IHC, IF, ICC, ELISA, …
  • …
For any specific request, plese contact us

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