Xanthurenic acid detection by IF in human midbrain Xanthurenic acid detection by IF in human midbrain Xanthurenic acid detection by IHC in human midbrain Affinity & specificity of anti-Xanthurenic acid antibody Xanthurenic acid

Xanthurenic acid detection by IF in human midbrain

Xanthurenic acid visualization by immunohistofluorescence in human caudate putamen. Staining highlights cytoplasmic accumulation of Xanthurenic acid in brain cells. Paraffin-embedded brain tissue section was subjected to pH=9 antigen retrieval followed by overnight incubation with primary antibody (dilution 1/500). After incubation with Alexa-488 conjugated secondary Ab, epifluorescence microscopy (100X) was used to capture the staining.

Xanthurenic acid antibody

Ref: IS009


The first and only validated anti-Xanthurenic acid antibody available for research use. Internal validation for IHC and IF of the 6C12-A12 mAb highlighted cytoplasmic presence of xanthurenic acid in human midbrain tissues.

 

Clonality Monoclonal antibody (clone 6C12-A12)
Host Mouse
Valided applications IHC / IF
Specie reactivity Reacts with all species
References Not yet cited to our knowledge
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Product information Protocols References Technical support Reviews

Product overview

 

Product name Xanthurenic acid antibody
Synonyms

Anti- Xanthurenic acid antibody

8-Hydroxy-4-oxo-1H-quinoline-2-carboxylic acid antibody

Xanthuric acid antibody

Xanthurenate antibody

8-Hydroxykynurenic acid antibody

Immunogen Conjugated Xanthurenic acid
Clone clone 6C12-A12
Specificity When tested in competitive ELISA, the anti-conjugated Xanthurenic acid antibody did not show any significant cross-reactivity with competitors Kynurenic acid and Quinaldic acid conujugates.
Lot number

140201

 

 

Storage

 

Form

Liquid

Purity Purified IgG
Concentration

0,5 mg/ml

Storage

Store at +4°C for short term (1-2 months). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles.

Material safety datasheet Download MSDS
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Protocols

Immunohistochemistry (IHC)

Dilute at 1:200-1:2000. Perform heat antigen retrieval (pH=9) before initiating IHC staining protocol on paraffin-embedded and frozen sections

Immunofluorescence (IF)

Dilute at 1:100-1:1000 on paraffin-embedded and frozen sections. Perform heat antigen retrieval and incubate with fluorescent secondary antibody conjugate

Comments

Optimal working dilutions must be determined by the end-user

Restrictions For research use only
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