





Kynurenine/Tryptophan ratio ELISA in IDOi-treated mice
Plasma samples were collected from MCA205 tumor-bearing mice treated with either vehicle or IDO inhibitor (GDC-0919) and determination of kynurenine to tryptophan ratio (KTR)
Kynurenine/Tryptophan ratio ELISA pack
Ref: ISE-2227The Kynurenine/Tryptophan ratio ELISA pack enables quantitative measurements of tryptophan catabolism along the kynurenine pathway in large numbers of samples. The two kits included in the pack are ready to use. Highly sensitive, with a minimum sample volume of 20µl, they permit the performance of longitudinal studies in mice.
Sample type |
Plasma, Serum, Cell culture supernatant, (Urine) |
Kit capacity | 2 x 96 tests |
Sensitivity |
LoD KYN: < 47.5 ng/ml |
Range |
KYN: 0/100 - 10000 ng/ml |
Species reactivity | Reacts with all species |
References | Citations in literature |

Shipping info :
(for 1 kit) | 81.00€ , 5 days |
Product information | Key steps | References | Technical support | Reviews |
Product overview
Product name |
Kynurenine/Tryptophan ratio ELISA pack |
Description | Two enzyme immunoassays (ELISA) allowing the quantitative determination of L-Kynurenine to L-Tryptophan ratio in urine, plasma and serum samples. |
Labels | CE |
Format | 2 x 96-well plate |
Samples | Plasma, serum, cell culture supernatant, (Urine) |
Minimum sample volume | 20 µL |
Cross specie-reactivity | React with all species |
Standard range | KYN: 0/100 - 10000 ng/ml TRP: 2.5 - 250 µg/ml |
Sensitivity |
LoD KYN: < 47.5 ng/ml |
Specificity |
No significant cross-reactivity was observed with L-Tryptophan and L-Kynurenine analogs. See product pages for L-Kynurenine ELISA and L-Tryptophan ELISA. |
Storage | Store at 2-8°C for to 6 months. |
Datasheets | Instructions for use - TRP kit, Instructions for use -KYN kit |
Key steps
Sample collection & storage |
Plasma/Serum: EDTA-, Heparin- or Citrate- samples stored at 2-8°C for up to 48h or -20°C for longer period (up to 6 months) |
Sample preparation |
KYN: Sample acylation (90 min) |
ELISA | Antisera overnight incubation, revelation and read steps (1h). |
Detailed protocol | Instructions for use - TRP kit, Instructions for use - KYN kit |
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