Quinolinic Acid ELISA kit
High Sensitivity, Plasma & Serum

Ref: IS-I-0100R
ELISAKynurenine pathwayTryptophan metabolismToxinsResearch ELISA kits (RUO)
DatasheetMSDSProtocol

Quinolinic acid (QA) is a metabolite produced along the Kynurenine Pathway, which converts the aminoacid Tryptophan to NAD+, a co-factor of many enzymatic reactions.

The Quinolinic Acid ELISA kit is optimized for the quantitation of Quinolinic Acid (QUIN or QA) within serum and plasma samples. This easy-to-use competitive assay is well-suited for both small and large series of samples. Working with a low sample volume of 25µL, this assay enables pre-clinical and clinical sample testings.

Sample typeSerum, Plasma
Capacity96 tests
Sensitivity35.9nM
Range150 – 12150nM
Assay timeSample acylation 120 min, ELISA overnight
ReactivityReacts with all species
ReferencesCited in 7 papers
Size

1 x 96 wells

539.00

18 in stock

Quantity
Total

539.00

Worldwide shipping

Select delivery location

Product overview

Product nameQuinolinic Acid ELISA kit
DescriptionCompetitive ELISA kit for the quantitative measurement of Quinolinic Acid levels in serum and plasma samples. For research use only
Format96-well plate
SamplesSerum, Plasma
Minimal sample volume25µL
ReactivityReacts with all species
Standard range25 – 2000ng/mL
Sensitivity

< 6ng/mL

SpecificityNo significant cross-reactivity was observed with Quinolinic Acid analogs such as Kynurenic acid, Xanthurenic acid, Kynurenine, Picolinic acid, 3-Hydroxy-Anthranilic Acid
Assay timeSample acylation 120 min and ELISA overnight
StorageStore at 2-8°C for up to 6 months
DatasheetsInstructions for useMaterial Safety Datasheet

Sample collection & storageSerum: Do not use lipemic, haemolytic samples, as well as samples containing precipitates or fibrin strands

Plasma (Heparin)

Store samples at 2-8°C for up to 48h or -20°C for longer period (up to 6 months)

Sample preparationSample acylation (120 min)
ELISAQuinolinic acid antiserum overnight incubation, revelation and read steps (1h)
Detailed protocolDownload instructions for use

Product citations

  • Advances in kynurenine analysis
    Check the article
    Authors : Mrstna et al., Clinica Chimica Acta
    2023-07
  • Atheroma plaque microenvironment stimulates kynurenine production by macrophages to induce endothelial adhesion molecules in the context of atherogenesis
    Check the article
    Authors : Dongen et al., bioRxiv
    2023-07
  • Unlocking the Secrets: Exploring the Biochemical Correlates of Suicidal Thoughts and Behaviors in Adults with Autism Spectrum Conditions
    Check the article
    Authors : Cremone et al., Biomedicines
    2023-04
  • Nociceptor-derived Reg3g prevents endotoxic death by targeting kynurenine pathway in microglia
    Check the article
    Authors : Sugisawa et al., Cell reports
    2022-03
  • Apathy is not associated with a panel of biomarkers in older adults with HIV disease
    Check the article
    Authors : Wood et al., Journal of psychosomatic research
    2021-11
  • Electrochemical Determination of Kynurenine Pathway Metabolites—Challenges and Perspectives
    Check the article
    Authors : Sadok et al., Sensors
    2021-10
  • Synbiotic Supplementation Improves Obesity Index and Metabolic Biomarkers in Thai Obese Adults: A Randomized Clinical Trial
    Check the article
    Authors : Chaiyasut et al, Foods
    2021-07

You may also like…

L-Kynurenine ELISA kit
High Sensitivity

BA-E-2200

Use In Vitro Diagnostics / Research
Samples ≥ 20µL Biological fluids
Key Feature High Sensitivity

L-Kynurenine Antibody – Mouse Monoclonal

IS003

Used for IF & IHC in mouse tissues & human brain, heart, & FFPE tumor tissues
Cited in 9 papers

440.00
VIEW PRODUCTADD

Quinolinic acid Antibody – Mouse Monoclonal

IS002

Used for IF & IHC in mouse & human paraffin-embedded brain tissues
Cited in 3 papers

440.00
VIEW PRODUCTADD

Kynurenine / Tryptophan ratio ELISA pack I High Sensitivity

ISE-2227

Use In Vitro Diagnostics / Research
Samples ≥ 20µL Biological fluids
Key Feature High Sensitivity

Quinolinic acid Antibody – Rabbit Polyclonal

IS1010

Used for IHC in human brain & lung samples
Cited 1 paper

440.00
VIEW PRODUCTADD