Cited in 11 papers, the anti-dopamine antibody IS1005 was used to evidence dopamine in mouse primary & iPS-derived neurons, human brain tissues and stem-cell derived brain organoids. Combined with the STAINperfect immunostaining kit A, this rabbit polyclonal antibody enables high-quality dopamine imaging.
When tested in competitive ELISA, the anti-conjugated Dopamine antibody did not show any significant cross reactivity with Tyramine and L-Dopa conjugates
Volume
50 µl
Lot number
140301
Expiration date
2025-08-01
Storage
Form
Liquid
Purity
Purified anti-serum
Storage
Store at +4°C for short term (6 months). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles
Dilute antibody with the antibody diluent provided in the STAINperfect immunostaining kit A. Use at 1/250 -1/1000 dilution. Follow the STAINperfect protocol suited to your sample
Comments
Optimal working dilutions must be determined by the end-user
Treating Parkinson’s Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration Check the article Authors : Mendes-Pinheiro et al., Cells 2023-11
Production of Highly Uniform Midbrain Organoids from Human Pluripotent Stem Cells Check the article Authors : Yao et al., Stem Cells International 2023-09
Dopamine Negatively Regulates Insulin Secretion Through Activation of D1-D2 Receptor Heteromer Check the article Authors : Uefune et al., Diabetes 2022-06
Alkyne-Tagged Dopamines as Versatile Analogue Probes for Dopaminergic System Analysis Check the article Authors : Nuriya et al., Analytical Chemistry 2021-07
Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Can Extensively Differentiate to Tyrosine-Hydroxylase-Expressing Dopamine-Secreting Neurons Check the article Authors : Yamane et al., Cells 2021-04
Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids Check the article Authors : Smits et al., Cell & tissue research 2020-07
Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson’s disease Check the article Authors : Nickels et al., Stem Cell Research 2020-06
Apoptosis signal regulating kinase 1 deletion mitigates α-synuclein pre-formed fibril propagation in mice Check the article Authors : Zhang et al., Neurobiology of aging 2019-09
Modeling Parkinson’s disease in midbrain-like organoids Check the article Authors : Smits et al., NPJ Parkinson's disease 2019-04
miR-34b/c Regulates Wnt1 and Enhances Mesencephalic Dopaminergic Neuron Differentiation Check the article Authors : De Gregorio et al., 2018-03
Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells Check the article Authors : Monzel et al., Step cell reports 2017-05
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