Kynurenic acid detection in human caudate putamen by IHC Kynurenic acid detection in human caudate putamen by IHC Affinity & specificity of the Kynurenic acid polyclonal antibody Kynurenic acid (KYNA)

Kynurenic acid detection in human caudate putamen by IHC

Immunohistochemistry (IHC) reveals kynurenic acid accumulation in the cytoplasm of glial cells in human caudate putamen. Paraffin-embedded brain tissue section was subjected to pH=6 antigen retrieval followed by overnight incubation with the primary anti-kynurenic acid polyclonal antibody (dilution 1/2000). After incubation with polymer-conjugated secondary Ab, DAB was used to visualize the staining.

Kynurenic acid polyclonal antibody

Ref: IS1011

 

The anti-Kynurenic acid (KYNA) rabbit polyclonal antibody proved to work at 1/2000 dilution on paraffin-embedded tissues, a single vial thus catering for approximately 400 stainings.

Clonality Polyclonal antibody
Host Rabbit (see anti-KYNA mouse mAb)
Valided applications IHC
Specie reactivity Reacts with all species
References Not yet cited to our knowledge. 
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Product information Protocols References Technical support Reviews

Product overview

 

Product name Kynurenic acid polyclonal antibody
Synonyms

Kinurenic acid polyclonal antibody

4-Hydroxyquinoline-2-carboxylic acid polyclonal antibody

KYNA polyclonal antibody

Immunogen Conjugated kynurenic acid
Specificity When tested in competitive ELISA, the anti-Kynurenic polyclonal antibody did not show any significant cross reactivity with Quinaldic and Xanthurenic conjugates.
Lot number

140401



Storage

 

Form

Liquid

Purity Purified anti-serum
Storage
Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles
Material safety datasheet

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Protocols

Immunohistochemistry (IHC)

Dilute at 1:200-1:2000. Perform heat antigen retrieval (pH=6) before initiating IHC staining protocol on paraffin-embedded and frozen sections

Comments

Optimal working dilutions must be determined by the end-user

Restrictions For research use only
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