Kynurenic Acid ELISA kit
High Sensitivity – Serum

Ref: IS-I-0200R
Kynurenine pathwayTryptophan metabolismResearch ELISA kits (RUO)ELISA
DatasheetProtocolMSDS

Kynurenic acid (KYNA) is a downstream metabolite produced along the Kynurenine Pathway well-known to possess several neuromodulatory functions, as well as immuno-modulatory properties. Measurement of KYNA in biological samples has been presented as a possible biomarker in several diseases including neurological or psychiatric disorders.

The Kynurenic Acid ELISA kit is optimized for the quantitation of Kynurenic Acid (KYNA) within serum samples. This easy-to-use competitive assay is well-suited for both small and large series of samples. Working with a 50µL sample volume, this assay enables pre-clinical and clinical sample testings.

Sample type Serum
Capacity 96 tests
Sensitivity 2.8nM
Range 10 – 391nM
Assay time Sample derivatization 90 min, ELISA overnight
Reactivity Reacts with all species
References Cited in 5 papers
Size

1 x 96 wells

649.00

30 in stock

Quantity
Total

649.00

Worldwide shipping

Select delivery location

Product overview

Product name Kynurenic Acid ELISA kit
Description Competitive ELISA kit for the quantitative measurement of Kynurenic Acid in serum samples. For research use only
Format 96-well plate
Samples Serum
Minimal sample volume 50µL
Reactivity Reacts with all species
Standard range 1.40 – 74ng/mL
Sensitivity

0.53ng/mL

Specificity No significant cross-reactivity was observed with Kynurenic Acid analogs such as Quinolinic Acid, Xanthurenic acid, Kynurenine, Picolinic acid, 3-Hydroxy-Anthranilic Acid
Assay time Sample derivatization 90 min and ELISA overnight
Storage Store at 2-8°C for up to 6 months
Datasheets Instructions for useMaterial Safety Datasheet

Sample collection & storage Serum: Do not use lipemic, haemolytic samples, as well as samples containing precipitates or fibrin strands

Store samples at 2-8°C for up to 48h or -20°C for longer period (up to 6 months)

Sample preparation Sample derivatization (90 min)
ELISA Kynurenic acid antiserum overnight incubation, revelation and read steps (1h)
Detailed protocol Download instructions for use

Product citations

  • Advances in kynurenine analysis
    Check the article
    Authors : Mrstna et al., Clinica Chimica Acta
    2023-07
  • Atheroma plaque microenvironment stimulates kynurenine production by macrophages to induce endothelial adhesion molecules in the context of atherogenesis
    Check the article
    Authors : Dongen et al., bioRxiv
    2023-07
  • Unlocking the Secrets: Exploring the Biochemical Correlates of Suicidal Thoughts and Behaviors in Adults with Autism Spectrum Conditions
    Check the article
    Authors : Cremone et al., Biomedicines
    2023-04
  • Alzheimer’s-like signaling in brains of COVID-19 patients
    Check the article
    Authors : Reiken et al., Alzheimer's & Dementia
    2022-02
  • Electrochemical Determination of Kynurenine Pathway Metabolites—Challenges and Perspectives
    Check the article
    Authors : Sadok et al., Sensors
    2021-10

You may also like…

L-Kynurenine ELISA kit
High Sensitivity

BA-E-2200

Use In Vitro Diagnostics / Research
Samples ≥ 20µL Biological fluids
Key Feature High Sensitivity

Quinolinic Acid ELISA kit
High Sensitivity, Plasma & Serum

IS-I-0100R

Use Research
Samples Plasma, Serum (25µl)
Feature High Sensitivity

539.00
VIEW PRODUCTADD

Kynurenic acid Antibody – Mouse Monoclonal

IS010

Used for IHC/IF in paraffin-embedded human brain tissues
Cited in literature

 

440.00
VIEW PRODUCTADD

Kynurenic acid Antibody – Rabbit Polyclonal

IS1011

Used for IHC in paraffin-embedded human brain tissues

440.00
VIEW PRODUCTADD

Kynurenine / Tryptophan ratio ELISA pack I High Sensitivity

ISE-2227

Use In Vitro Diagnostics / Research
Samples ≥ 20µL Biological fluids
Key Feature High Sensitivity